Pivotal involvement of Fcγ receptor IIA in the neutralization of lipopolysaccharide signaling via a potent novel anti-TLR4 monoclonal antibody 15C1

Journal of Biological Chemistry

Volumn 282, Issue 48, 2007, Pages 34817-34827

  Dunn Siegrist, Irene ^b   Leger, Olivier ^a   Daubeuf, Bruno ^a   Poitevin, Yves ^a   Dépis, Fabien ^a   Herren, Suzanne ^a   Kosco Vilbois, Marie ^a   Dean, Yann ^a   Pugin, Jérôme ^b   Elson, Greg ^a  

^a NOVIMMUNE SA   (Switzerland)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPES; LIPOPOLYSACCHARIDE; NEUTRALIZATION;

CELLS; CHEMICAL ACTIVATION; ENZYME INHIBITION; MONOCLONAL ANTIBODIES;

POLYSACCHARIDES;

FC RECEPTOR IIA; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 15C1; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; EPITOPE; FC RECEPTOR; LEUKOCYTE ANTIGEN; TLR4 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; GENOTYPE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL CULTURE; CELL LINE; CHEMISTRY; DOSE RESPONSE; GENETIC POLYMORPHISM; METABOLISM; MOLECULAR CLONING; MOUSE; VASCULAR ENDOTHELIUM;

MAMMALIA; NEGIBACTERIA;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; CELL LINE; CELLS, CULTURED; CLONING, MOLECULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; EPITOPES; HUMANS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; POLYMORPHISM, GENETIC; RECEPTORS, IGG; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 36849069342     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706440200     Document Type: Article

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