-
1
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M, (2012) An integrated encyclopedia of DNA elements in the human genome. Nature 489: 57-74
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Bernstein, B.E.1
Birney, E.2
Dunham, I.3
Green, E.D.4
Gunter, C.5
Snyder, M.6
-
2
-
-
79960433506
-
Hfq and its constellation of RNA
-
Vogel J, Luisi BF, (2011) Hfq and its constellation of RNA. Nat Rev Microbiol 9: 578-589
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 578-589
-
-
Vogel, J.1
Luisi, B.F.2
-
3
-
-
33847187076
-
Non-coding RNAs: Lessons from the small nuclear and small nucleolar RNAs
-
Matera AG, Terns RM, Terns MP, (2007) Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs. Nat Rev Mol Cell Biol 8: 209-220
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 209-220
-
-
Matera, A.G.1
Terns, R.M.2
Terns, M.P.3
-
4
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. Elegans
-
Wightman B, Ha I, Ruvkun G, (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. Elegans. Cell 75: 855-862
-
(1993)
Cell
, vol.75
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
5
-
-
0027751663
-
The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V, (1993) The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
6
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
7
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB, (2003) Prediction of mammalian microRNA targets. Cell 115: 787-798
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
8
-
-
77955475953
-
Expanding the microRNA targeting code: Functional sites with centered pairing
-
Shin C, Nam JW, Farh KK, Chiang HR, Shkumatava A, Bartel DP, (2010) Expanding the microRNA targeting code: functional sites with centered pairing. Mol Cell 38: 789-802
-
(2010)
Mol Cell
, vol.38
, pp. 789-802
-
-
Shin, C.1
Nam, J.W.2
Farh, K.K.3
Chiang, H.R.4
Shkumatava, A.5
Bartel, D.P.6
-
9
-
-
84876935138
-
Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding
-
Helwak A, Kudla G, Dudnakova T, Tollervey D, (2013) Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding. Cell 153: 654-665
-
(2013)
Cell
, vol.153
, pp. 654-665
-
-
Helwak, A.1
Kudla, G.2
Dudnakova, T.3
Tollervey, D.4
-
10
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP, (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
11
-
-
49949117302
-
Widespread changes in protein synthesis induced by microRNAs
-
Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N, (2008) Widespread changes in protein synthesis induced by microRNAs. Nature 455: 58-63
-
(2008)
Nature
, vol.455
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
12
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D, Villen J, Shin C, Camargo FD, Gygi SP, Bartel DP, (2008) The impact of microRNAs on protein output. Nature 455: 64-71
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
13
-
-
0024963695
-
A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. Elegans
-
Ambros V, (1989) A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. Elegans. Cell 57: 49-57
-
(1989)
Cell
, vol.57
, pp. 49-57
-
-
Ambros, V.1
-
14
-
-
67349123973
-
Redefining microRNA targets
-
Seitz H, (2009) Redefining microRNA targets. Curr Biol 19: 870-873
-
(2009)
Curr Biol
, vol.19
, pp. 870-873
-
-
Seitz, H.1
-
15
-
-
0037009364
-
MicroRNA maturation: Stepwise processing and subcellular localization
-
Lee Y, Jeon K, Lee JT, Kim S, Kim VN, (2002) MicroRNA maturation: stepwise processing and subcellular localization. EMBO J 21: 4663-4670
-
(2002)
EMBO J
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
16
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH, Kim VN, (2004) MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23: 4051-4060
-
(2004)
EMBO J
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
17
-
-
9344235449
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
-
Cai X, Hagedorn CH, Cullen BR, (2004) Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10: 1957-1966
-
(2004)
RNA
, vol.10
, pp. 1957-1966
-
-
Cai, X.1
Hagedorn, C.H.2
Cullen, B.R.3
-
18
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
-
Han J, Lee Y, Yeom KH, Nam JW, Heo I, Rhee JK, Sohn SY, Cho Y, Zhang BT, Kim VN, (2006) Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125: 887-901
-
(2006)
Cell
, vol.125
, pp. 887-901
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Nam, J.W.4
Heo, I.5
Rhee, J.K.6
Sohn, S.Y.7
Cho, Y.8
Zhang, B.T.9
Kim, V.N.10
-
19
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Radmark O, Kim S, et al (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425: 415-419
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
-
20
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN, (2004) The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 18: 3016-3027
-
(2004)
Genes Dev
, vol.18
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
21
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ, (2004) Processing of primary microRNAs by the Microprocessor complex. Nature 432: 231-235
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
22
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R, (2004) The Microprocessor complex mediates the genesis of microRNAs. Nature 432: 235-240
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
Shiekhattar, R.7
-
23
-
-
10344248903
-
The human DiGeorge syndrome critical region gene 8 and Its D. Melanogaster homolog are required for miRNA biogenesis
-
Landthaler M, Yalcin A, Tuschl T, (2004) The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 14: 2162-2167
-
(2004)
Curr Biol
, vol.14
, pp. 2162-2167
-
-
Landthaler, M.1
Yalcin, A.2
Tuschl, T.3
-
24
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, Cullen BR, (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17: 3011-3016
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
MacAra, I.G.3
Cullen, B.R.4
-
25
-
-
1642499415
-
Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
-
Bohnsack MT, Czaplinski K, Gorlich D, (2004) Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10: 185-191
-
(2004)
RNA
, vol.10
, pp. 185-191
-
-
Bohnsack, M.T.1
Czaplinski, K.2
Gorlich, D.3
-
26
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U, (2004) Nuclear export of microRNA precursors. Science 303: 95-98
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
27
-
-
4444230672
-
Structural requirements for pre-microRNA binding and nuclear export by Exportin 5
-
Zeng Y, Cullen BR, (2004) Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. Nucleic Acids Res 32: 4776-4785
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 4776-4785
-
-
Zeng, Y.1
Cullen, B.R.2
-
28
-
-
29144431656
-
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
-
Maniataki E, Mourelatos Z, (2005) A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev 19: 2979-2990
-
(2005)
Genes Dev
, vol.19
, pp. 2979-2990
-
-
Maniataki, E.1
Mourelatos, Z.2
-
29
-
-
27744537851
-
Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
-
Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R, (2005) Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123: 631-640
-
(2005)
Cell
, vol.123
, pp. 631-640
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Cooch, N.3
Shiekhattar, R.4
-
30
-
-
27144550559
-
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
-
Haase AD, Jaskiewicz L, Zhang H, Laine S, Sack R, Gatignol A, Filipowicz W, (2005) TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep 6: 961-967
-
(2005)
EMBO Rep
, vol.6
, pp. 961-967
-
-
Haase, A.D.1
Jaskiewicz, L.2
Zhang, H.3
Laine, S.4
Sack, R.5
Gatignol, A.6
Filipowicz, W.7
-
31
-
-
32544460452
-
The role of PACT in the RNA silencing pathway
-
Lee Y, Hur I, Park SY, Kim YK, Suh MR, Kim VN, (2006) The role of PACT in the RNA silencing pathway. EMBO J 25: 522-532
-
(2006)
EMBO J
, vol.25
, pp. 522-532
-
-
Lee, Y.1
Hur, I.2
Park, S.Y.3
Kim, Y.K.4
Suh, M.R.5
Kim, V.N.6
-
32
-
-
1842816517
-
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
-
Lee YS, Nakahara K, Pham JW, Kim K, He Z, Sontheimer EJ, Carthew RW, (2004) Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117: 69-81
-
(2004)
Cell
, vol.117
, pp. 69-81
-
-
Lee, Y.S.1
Nakahara, K.2
Pham, J.W.3
Kim, K.4
He, Z.5
Sontheimer, E.J.6
Carthew, R.W.7
-
33
-
-
22744433240
-
Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
-
Forstemann K, Tomari Y, Du T, Vagin VV, Denli AM, Bratu DP, Klattenhoff C, Theurkauf WE, Zamore PD, (2005) Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol 3: e236
-
(2005)
PLoS Biol
, vol.3
-
-
Forstemann, K.1
Tomari, Y.2
Du, T.3
Vagin, V.V.4
Denli, A.M.5
Bratu, D.P.6
Klattenhoff, C.7
Theurkauf, W.E.8
Zamore, P.D.9
-
34
-
-
22744454230
-
Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells
-
Saito K, Ishizuka A, Siomi H, Siomi MC, (2005) Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol 3: e235
-
(2005)
PLoS Biol
, vol.3
-
-
Saito, K.1
Ishizuka, A.2
Siomi, H.3
Siomi, M.C.4
-
35
-
-
23044462450
-
Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila
-
Jiang F, Ye X, Liu X, Fincher L, McKearin D, Liu Q, (2005) Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila. Genes Dev 19: 1674-1679
-
(2005)
Genes Dev
, vol.19
, pp. 1674-1679
-
-
Jiang, F.1
Ye, X.2
Liu, X.3
Fincher, L.4
McKearin, D.5
Liu, Q.6
-
36
-
-
34447097693
-
Intronic microRNA precursors that bypass Drosha processing
-
Ruby JG, Jan CH, Bartel DP, (2007) Intronic microRNA precursors that bypass Drosha processing. Nature 448: 83-86
-
(2007)
Nature
, vol.448
, pp. 83-86
-
-
Ruby, J.G.1
Jan, C.H.2
Bartel, D.P.3
-
37
-
-
34447107760
-
The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
-
Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC, (2007) The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 130: 89-100
-
(2007)
Cell
, vol.130
, pp. 89-100
-
-
Okamura, K.1
Hagen, J.W.2
Duan, H.3
Tyler, D.M.4
Lai, E.C.5
-
38
-
-
77953183812
-
A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
-
Cheloufi S, Dos Santos CO, Chong MM, Hannon GJ, (2010) A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature 465: 584-589
-
(2010)
Nature
, vol.465
, pp. 584-589
-
-
Cheloufi, S.1
Dos Santos, C.O.2
Chong, M.M.3
Hannon, G.J.4
-
39
-
-
77953897182
-
A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity
-
Cifuentes D, Xue H, Taylor DW, Patnode H, Mishima Y, Cheloufi S, Ma E, Mane S, Hannon GJ, Lawson ND, et al (2010) A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science 328: 1694-1698
-
(2010)
Science
, vol.328
, pp. 1694-1698
-
-
Cifuentes, D.1
Xue, H.2
Taylor, D.W.3
Patnode, H.4
Mishima, Y.5
Cheloufi, S.6
Ma, E.7
Mane, S.8
Hannon, G.J.9
Lawson, N.D.10
-
40
-
-
69949127421
-
Structural determinants of miRNAs for RISC loading and slicer-independent unwinding
-
Kawamata T, Seitz H, Tomari Y, (2009) Structural determinants of miRNAs for RISC loading and slicer-independent unwinding. Nat Struct Mol Biol 16: 953-960
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 953-960
-
-
Kawamata, T.1
Seitz, H.2
Tomari, Y.3
-
41
-
-
77449128456
-
ATP-dependent human RISC assembly pathways
-
Yoda M, Kawamata T, Paroo Z, Ye X, Iwasaki S, Liu Q, Tomari Y, (2010) ATP-dependent human RISC assembly pathways. Nat Struct Mol Biol 17: 17-23
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 17-23
-
-
Yoda, M.1
Kawamata, T.2
Paroo, Z.3
Ye, X.4
Iwasaki, S.5
Liu, Q.6
Tomari, Y.7
-
42
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu J, Carmell MA, Rivas FV, Marsden CG, Thomson JM, Song JJ, Hammond SM, Joshua-Tor L, Hannon GJ, (2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science 305: 1437-1441
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
43
-
-
3242736704
-
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
-
Meister G, Landthaler M, Patkaniowska A, Dorsett Y, Teng G, Tuschl T, (2004) Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell 15: 185-197
-
(2004)
Mol Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
44
-
-
3142729150
-
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
-
Okamura K, Ishizuka A, Siomi H, Siomi MC, (2004) Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev 18: 1655-1666
-
(2004)
Genes Dev
, vol.18
, pp. 1655-1666
-
-
Okamura, K.1
Ishizuka, A.2
Siomi, H.3
Siomi, M.C.4
-
45
-
-
34447291764
-
Drosophila microRNAs are sorted into functionally distinct Argonaute complexes after production by Dicer-1
-
Forstemann K, Horwich MD, Wee L, Tomari Y, Zamore PD, (2007) Drosophila microRNAs are sorted into functionally distinct Argonaute complexes after production by Dicer-1. Cell 130: 287-297
-
(2007)
Cell
, vol.130
, pp. 287-297
-
-
Forstemann, K.1
Horwich, M.D.2
Wee, L.3
Tomari, Y.4
Zamore, P.D.5
-
46
-
-
34447642555
-
Sorting of Drosophila small silencing RNAs
-
Tomari Y, Du T, Zamore PD, (2007) Sorting of Drosophila small silencing RNAs. Cell 130: 299-308
-
(2007)
Cell
, vol.130
, pp. 299-308
-
-
Tomari, Y.1
Du, T.2
Zamore, P.D.3
-
47
-
-
70449127022
-
Hierarchical rules for Argonaute loading in Drosophila
-
Czech B, Zhou R, Erlich Y, Brennecke J, Binari R, Villalta C, Gordon A, Perrimon N, Hannon GJ, (2009) Hierarchical rules for Argonaute loading in Drosophila. Mol Cell 36: 445-456
-
(2009)
Mol Cell
, vol.36
, pp. 445-456
-
-
Czech, B.1
Zhou, R.2
Erlich, Y.3
Brennecke, J.4
Binari, R.5
Villalta, C.6
Gordon, A.7
Perrimon, N.8
Hannon, G.J.9
-
48
-
-
70449122099
-
Distinct mechanisms for microRNA strand selection by Drosophila Argonautes
-
Okamura K, Liu N, Lai EC, (2009) Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Mol Cell 36: 431-444
-
(2009)
Mol Cell
, vol.36
, pp. 431-444
-
-
Okamura, K.1
Liu, N.2
Lai, E.C.3
-
49
-
-
75649129754
-
Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
-
Ghildiyal M, Xu J, Seitz H, Weng Z, Zamore PD, (2010) Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway. RNA 16: 43-56
-
(2010)
RNA
, vol.16
, pp. 43-56
-
-
Ghildiyal, M.1
Xu, J.2
Seitz, H.3
Weng, Z.4
Zamore, P.D.5
-
50
-
-
77953479619
-
Structural basis for 5′nucleotide base-specific recognition of guide RNA by human AGO2
-
Frank F, Sonenberg N, Nagar B, (2010) Structural basis for 5′nucleotide base-specific recognition of guide RNA by human AGO2. Nature 465: 818-822
-
(2010)
Nature
, vol.465
, pp. 818-822
-
-
Frank, F.1
Sonenberg, N.2
Nagar, B.3
-
51
-
-
77955478739
-
Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes
-
Iwasaki S, Kobayashi M, Yoda M, Sakaguchi Y, Katsuma S, Suzuki T, Tomari Y, (2010) Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes. Mol Cell 39: 292-299
-
(2010)
Mol Cell
, vol.39
, pp. 292-299
-
-
Iwasaki, S.1
Kobayashi, M.2
Yoda, M.3
Sakaguchi, Y.4
Katsuma, S.5
Suzuki, T.6
Tomari, Y.7
-
52
-
-
77951712353
-
HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells
-
Johnston M, Geoffroy MC, Sobala A, Hay R, Hutvagner G, (2010) HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells. Mol Biol Cell 21: 1462-1469
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1462-1469
-
-
Johnston, M.1
Geoffroy, M.C.2
Sobala, A.3
Hay, R.4
Hutvagner, G.5
-
53
-
-
77955479987
-
In vitro assembly of plant RNA-induced silencing complexes facilitated by molecular chaperone HSP90
-
Iki T, Yoshikawa M, Nishikiori M, Jaudal MC, Matsumoto-Yokoyama E, Mitsuhara I, Meshi T, Ishikawa M, (2010) In vitro assembly of plant RNA-induced silencing complexes facilitated by molecular chaperone HSP90. Mol Cell 39: 282-291
-
(2010)
Mol Cell
, vol.39
, pp. 282-291
-
-
Iki, T.1
Yoshikawa, M.2
Nishikiori, M.3
Jaudal, M.C.4
Matsumoto-Yokoyama, E.5
Mitsuhara, I.6
Meshi, T.7
Ishikawa, M.8
-
55
-
-
56249145105
-
Structure of the guide-strand-containing Argonaute silencing complex
-
Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ, (2008) Structure of the guide-strand-containing Argonaute silencing complex. Nature 456: 209-213
-
(2008)
Nature
, vol.456
, pp. 209-213
-
-
Wang, Y.1
Sheng, G.2
Juranek, S.3
Tuschl, T.4
Patel, D.J.5
-
56
-
-
84862558196
-
Structure of yeast Argonaute with guide RNA
-
Nakanishi K, Weinberg DE, Bartel DP, Patel DJ, (2012) Structure of yeast Argonaute with guide RNA. Nature 486: 368-374
-
(2012)
Nature
, vol.486
, pp. 368-374
-
-
Nakanishi, K.1
Weinberg, D.E.2
Bartel, D.P.3
Patel, D.J.4
-
57
-
-
84861451595
-
The crystal structure of human Argonaute2
-
Schirle NT, MacRae IJ, (2012) The crystal structure of human Argonaute2. Science 336: 1037-1040
-
(2012)
Science
, vol.336
, pp. 1037-1040
-
-
Schirle, N.T.1
MacRae, I.J.2
-
58
-
-
84863624199
-
The structure of human Argonaute-2 in complex with miR-20a
-
Elkayam E, Kuhn CD, Tocilj A, Haase AD, Greene EM, Hannon GJ, Joshua-Tor L, (2012) The structure of human Argonaute-2 in complex with miR-20a. Cell 150: 100-110
-
(2012)
Cell
, vol.150
, pp. 100-110
-
-
Elkayam, E.1
Kuhn, C.D.2
Tocilj, A.3
Haase, A.D.4
Greene, E.M.5
Hannon, G.J.6
Joshua-Tor, L.7
-
59
-
-
33746055678
-
MRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
-
Behm-Ansmant I, Rehwinkel J, Doerks T, Stark A, Bork P, Izaurralde E, (2006) mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev 20: 1885-1898
-
(2006)
Genes Dev
, vol.20
, pp. 1885-1898
-
-
Behm-Ansmant, I.1
Rehwinkel, J.2
Doerks, T.3
Stark, A.4
Bork, P.5
Izaurralde, E.6
-
60
-
-
41649115420
-
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay
-
Eulalio A, Huntzinger E, Izaurralde E, (2008) GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nat Struct Mol Biol 15: 346-353
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 346-353
-
-
Eulalio, A.1
Huntzinger, E.2
Izaurralde, E.3
-
61
-
-
80053580757
-
GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets
-
Braun JE, Huntzinger E, Fauser M, Izaurralde E, (2011) GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. Mol Cell 44: 120-133
-
(2011)
Mol Cell
, vol.44
, pp. 120-133
-
-
Braun, J.E.1
Huntzinger, E.2
Fauser, M.3
Izaurralde, E.4
-
62
-
-
80555131046
-
MiRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs
-
Chekulaeva M, Mathys H, Zipprich JT, Attig J, Colic M, Parker R, Filipowicz W, (2011) miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs. Nat Struct Mol Biol 18: 1218-1226
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1218-1226
-
-
Chekulaeva, M.1
Mathys, H.2
Zipprich, J.T.3
Attig, J.4
Colic, M.5
Parker, R.6
Filipowicz, W.7
-
63
-
-
80555150587
-
MiRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT
-
Fabian MR, Cieplak MK, Frank F, Morita M, Green J, Srikumar T, Nagar B, Yamamoto T, Raught B, Duchaine TF, et al (2011) miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. Nat Struct Mol Biol 18: 1211-1217
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1211-1217
-
-
Fabian, M.R.1
Cieplak, M.K.2
Frank, F.3
Morita, M.4
Green, J.5
Srikumar, T.6
Nagar, B.7
Yamamoto, T.8
Raught, B.9
Duchaine, T.F.10
-
64
-
-
28044457883
-
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function
-
Humphreys DT, Westman BJ, Martin DI, Preiss T, (2005) MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function. Proc Natl Acad Sci USA 102: 16961-16966
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16961-16966
-
-
Humphreys, D.T.1
Westman, B.J.2
Martin, D.I.3
Preiss, T.4
-
65
-
-
24644480213
-
Inhibition of translational initiation by let-7 MicroRNA in human cells
-
Pillai RS, Bhattacharyya SN, Artus CG, Zoller T, Cougot N, Basyuk E, Bertrand E, Filipowicz W, (2005) Inhibition of translational initiation by let-7 MicroRNA in human cells. Science 309: 1573-1576
-
(2005)
Science
, vol.309
, pp. 1573-1576
-
-
Pillai, R.S.1
Bhattacharyya, S.N.2
Artus, C.G.3
Zoller, T.4
Cougot, N.5
Basyuk, E.6
Bertrand, E.7
Filipowicz, W.8
-
66
-
-
33645119514
-
MicroRNAs direct rapid deadenylation of mRNA
-
Wu L, Fan J, Belasco JG, (2006) MicroRNAs direct rapid deadenylation of mRNA. Proc Natl Acad Sci USA 103: 4034-4039
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 4034-4039
-
-
Wu, L.1
Fan, J.2
Belasco, J.G.3
-
67
-
-
84856375470
-
Translational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish
-
Mishima Y, Fukao A, Kishimoto T, Sakamoto H, Fujiwara T, Inoue K, (2012) Translational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish. Proc Natl Acad Sci USA 109: 1104-1109
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1104-1109
-
-
Mishima, Y.1
Fukao, A.2
Kishimoto, T.3
Sakamoto, H.4
Fujiwara, T.5
Inoue, K.6
-
68
-
-
83555161676
-
PABP is not essential for microRNA-mediated translational repression and deadenylation in vitro
-
Fukaya T, Tomari Y, (2011) PABP is not essential for microRNA-mediated translational repression and deadenylation in vitro. EMBO J 30: 4998-5009
-
(2011)
EMBO J
, vol.30
, pp. 4998-5009
-
-
Fukaya, T.1
Tomari, Y.2
-
69
-
-
84871681585
-
MicroRNAs Mediate Gene Silencing via Multiple Different Pathways in Drosophila
-
Fukaya T, Tomari Y, (2012) MicroRNAs Mediate Gene Silencing via Multiple Different Pathways in Drosophila. Mol Cell 48: 825-836
-
(2012)
Mol Cell
, vol.48
, pp. 825-836
-
-
Fukaya, T.1
Tomari, Y.2
-
70
-
-
84859632747
-
MiRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay
-
Djuranovic S, Nahvi A, Green R, (2012) miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Science 336: 237-240
-
(2012)
Science
, vol.336
, pp. 237-240
-
-
Djuranovic, S.1
Nahvi, A.2
Green, R.3
-
71
-
-
84862778053
-
Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish
-
Bazzini AA, Lee MT, Giraldez AJ, (2012) Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish. Science 336: 233-237
-
(2012)
Science
, vol.336
, pp. 233-237
-
-
Bazzini, A.A.1
Lee, M.T.2
Giraldez, A.J.3
-
72
-
-
84864872623
-
Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells
-
Bethune J, Artus-Revel CG, Filipowicz W, (2012) Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells. EMBO Rep 13: 716-723
-
(2012)
EMBO Rep
, vol.13
, pp. 716-723
-
-
Bethune, J.1
Artus-Revel, C.G.2
Filipowicz, W.3
-
73
-
-
58449134534
-
Small silencing RNAs: An expanding universe
-
Ghildiyal M, Zamore PD, (2009) Small silencing RNAs: an expanding universe. Nat Rev Genet 10: 94-108
-
(2009)
Nat Rev Genet
, vol.10
, pp. 94-108
-
-
Ghildiyal, M.1
Zamore, P.D.2
-
74
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC, (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
75
-
-
34547587566
-
Antiviral immunity directed by small RNAs
-
Ding SW, Voinnet O, (2007) Antiviral immunity directed by small RNAs. Cell 130: 413-426
-
(2007)
Cell
, vol.130
, pp. 413-426
-
-
Ding, S.W.1
Voinnet, O.2
-
76
-
-
84885583303
-
Antiviral RNA interference in mammalian cells
-
Maillard PV, Ciaudo C, Marchais A, Li Y, Jay F, Ding SW, Voinnet O, (2013) Antiviral RNA interference in mammalian cells. Science 342: 235-238
-
(2013)
Science
, vol.342
, pp. 235-238
-
-
Maillard, P.V.1
Ciaudo, C.2
Marchais, A.3
Li, Y.4
Jay, F.5
Ding, S.W.6
Voinnet, O.7
-
77
-
-
84885635441
-
RNA interference functions as an antiviral immunity mechanism in mammals
-
Li Y, Lu J, Han Y, Fan X, Ding SW, (2013) RNA interference functions as an antiviral immunity mechanism in mammals. Science 342: 231-234
-
(2013)
Science
, vol.342
, pp. 231-234
-
-
Li, Y.1
Lu, J.2
Han, Y.3
Fan, X.4
Ding, S.W.5
-
78
-
-
50149095122
-
Endogenous small interfering RNAs in animals
-
Okamura K, Lai EC, (2008) Endogenous small interfering RNAs in animals. Nat Rev Mol Cell Biol 9: 673-678
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 673-678
-
-
Okamura, K.1
Lai, E.C.2
-
79
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ, (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
80
-
-
1842766252
-
A Dicer-2-dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila
-
Pham JW, Pellino JL, Lee YS, Carthew RW, Sontheimer EJ, (2004) A Dicer-2-dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117: 83-94
-
(2004)
Cell
, vol.117
, pp. 83-94
-
-
Pham, J.W.1
Pellino, J.L.2
Lee, Y.S.3
Carthew, R.W.4
Sontheimer, E.J.5
-
81
-
-
0141868916
-
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
-
Liu Q, Rand TA, Kalidas S, Du F, Kim HE, Smith DP, Wang X, (2003) R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301: 1921-1925
-
(2003)
Science
, vol.301
, pp. 1921-1925
-
-
Liu, Q.1
Rand, T.A.2
Kalidas, S.3
Du, F.4
Kim, H.E.5
Smith, D.P.6
Wang, X.7
-
82
-
-
70350569212
-
Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences
-
Hartig JV, Esslinger S, Bottcher R, Saito K, Forstemann K, (2009) Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences. EMBO J 28: 2932-2944
-
(2009)
EMBO J
, vol.28
, pp. 2932-2944
-
-
Hartig, J.V.1
Esslinger, S.2
Bottcher, R.3
Saito, K.4
Forstemann, K.5
-
83
-
-
70349147889
-
Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform
-
Zhou R, Czech B, Brennecke J, Sachidanandam R, Wohlschlegel JA, Perrimon N, Hannon GJ, (2009) Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA 15: 1886-1895
-
(2009)
RNA
, vol.15
, pp. 1886-1895
-
-
Zhou, R.1
Czech, B.2
Brennecke, J.3
Sachidanandam, R.4
Wohlschlegel, J.A.5
Perrimon, N.6
Hannon, G.J.7
-
84
-
-
77149173174
-
Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila
-
Miyoshi K, Miyoshi T, Hartig JV, Siomi H, Siomi MC, (2010) Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila. RNA 16: 506-515
-
(2010)
RNA
, vol.16
, pp. 506-515
-
-
Miyoshi, K.1
Miyoshi, T.2
Hartig, J.V.3
Siomi, H.4
Siomi, M.C.5
-
85
-
-
79954630204
-
Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila
-
Hartig JV, Forstemann K, (2011) Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila. Nucleic Acids Res 39: 3836-3851
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 3836-3851
-
-
Hartig, J.V.1
Forstemann, K.2
-
86
-
-
0036845374
-
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
-
Zhang H, Kolb FA, Brondani V, Billy E, Filipowicz W, (2002) Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J 21: 5875-5885
-
(2002)
EMBO J
, vol.21
, pp. 5875-5885
-
-
Zhang, H.1
Kolb, F.A.2
Brondani, V.3
Billy, E.4
Filipowicz, W.5
-
87
-
-
0036847540
-
Ribonuclease activity and RNA binding of recombinant human Dicer
-
Provost P, Dishart D, Doucet J, Frendewey D, Samuelsson B, Radmark O, (2002) Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J 21: 5864-5874
-
(2002)
EMBO J
, vol.21
, pp. 5864-5874
-
-
Provost, P.1
Dishart, D.2
Doucet, J.3
Frendewey, D.4
Samuelsson, B.5
Radmark, O.6
-
88
-
-
34547115237
-
Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA
-
Kok KH, Ng MH, Ching YP, Jin DY, (2007) Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA. J Biol Chem 282: 17649-17657
-
(2007)
J Biol Chem
, vol.282
, pp. 17649-17657
-
-
Kok, K.H.1
Ng, M.H.2
Ching, Y.P.3
Jin, D.Y.4
-
89
-
-
44649136660
-
Autoinhibition of human dicer by its internal helicase domain
-
Ma E, MacRae IJ, Kirsch JF, Doudna JA, (2008) Autoinhibition of human dicer by its internal helicase domain. J Mol Biol 380: 237-243
-
(2008)
J Mol Biol
, vol.380
, pp. 237-243
-
-
Ma, E.1
MacRae, I.J.2
Kirsch, J.F.3
Doudna, J.A.4
-
90
-
-
84887865235
-
A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes
-
Flemr M, Malik R, Franke V, Nejepinska J, Sedlacek R, Vlahovicek K, Svoboda P, (2013) A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes. Cell 155: 807-816
-
(2013)
Cell
, vol.155
, pp. 807-816
-
-
Flemr, M.1
Malik, R.2
Franke, V.3
Nejepinska, J.4
Sedlacek, R.5
Vlahovicek, K.6
Svoboda, P.7
-
91
-
-
84881611871
-
A truncated form of dicer tilts the balance of RNA interference pathways
-
Sawh AN, Duchaine TF, (2013) A truncated form of dicer tilts the balance of RNA interference pathways. Cell Rep 4: 454-463
-
(2013)
Cell Rep
, vol.4
, pp. 454-463
-
-
Sawh, A.N.1
Duchaine, T.F.2
-
92
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T, (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
93
-
-
0035798415
-
ATP requirements and small interfering RNA structure in the RNA interference pathway
-
Nykanen A, Haley B, Zamore PD, (2001) ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107: 309-321
-
(2001)
Cell
, vol.107
, pp. 309-321
-
-
Nykanen, A.1
Haley, B.2
Zamore, P.D.3
-
94
-
-
77955426711
-
A direct role for Hsp90 in pre-RISC formation in Drosophila
-
Miyoshi T, Takeuchi A, Siomi H, Siomi MC, (2010) A direct role for Hsp90 in pre-RISC formation in Drosophila. Nat Struct Mol Biol 17: 1024-1026
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1024-1026
-
-
Miyoshi, T.1
Takeuchi, A.2
Siomi, H.3
Siomi, M.C.4
-
95
-
-
1642603943
-
RISC assembly defects in the Drosophila RNAi mutant armitage
-
Tomari Y, Du T, Haley B, Schwarz DS, Bennett R, Cook HA, Koppetsch BS, Theurkauf WE, Zamore PD, (2004) RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116: 831-841
-
(2004)
Cell
, vol.116
, pp. 831-841
-
-
Tomari, Y.1
Du, T.2
Haley, B.3
Schwarz, D.S.4
Bennett, R.5
Cook, H.A.6
Koppetsch, B.S.7
Theurkauf, W.E.8
Zamore, P.D.9
-
96
-
-
84876059864
-
MiRNA-like duplexes as RNAi triggers with improved specificity
-
Betancur JG, Yoda M, Tomari Y, (2012) miRNA-like duplexes as RNAi triggers with improved specificity. Front Genet 3: 127
-
(2012)
Front Genet
, vol.3
, pp. 127
-
-
Betancur, J.G.1
Yoda, M.2
Tomari, Y.3
-
97
-
-
79958825213
-
Structure of C3PO and mechanism of human RISC activation
-
Ye X, Huang N, Liu Y, Paroo Z, Huerta C, Li P, Chen S, Liu Q, Zhang H, (2011) Structure of C3PO and mechanism of human RISC activation. Nat Struct Mol Biol 18: 650-657
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 650-657
-
-
Ye, X.1
Huang, N.2
Liu, Y.3
Paroo, Z.4
Huerta, C.5
Li, P.6
Chen, S.7
Liu, Q.8
Zhang, H.9
-
98
-
-
84876591872
-
Multiple sensors ensure guide strand selection in human RNAi pathways
-
Noland CL, Doudna JA, (2013) Multiple sensors ensure guide strand selection in human RNAi pathways. RNA 19: 639-648
-
(2013)
RNA
, vol.19
, pp. 639-648
-
-
Noland, C.L.1
Doudna, J.A.2
-
99
-
-
27744590896
-
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
-
Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD, (2005) Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123: 607-620
-
(2005)
Cell
, vol.123
, pp. 607-620
-
-
Matranga, C.1
Tomari, Y.2
Shin, C.3
Bartel, D.P.4
Zamore, P.D.5
-
100
-
-
28444437427
-
Slicer function of Drosophila Argonautes and its involvement in RISC formation
-
Miyoshi K, Tsukumo H, Nagami T, Siomi H, Siomi MC, (2005) Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes Dev 19: 2837-2848
-
(2005)
Genes Dev
, vol.19
, pp. 2837-2848
-
-
Miyoshi, K.1
Tsukumo, H.2
Nagami, T.3
Siomi, H.4
Siomi, M.C.5
-
101
-
-
33645763485
-
Cleavage of the siRNA passenger strand during RISC assembly in human cells
-
Leuschner PJ, Ameres SL, Kueng S, Martinez J, (2006) Cleavage of the siRNA passenger strand during RISC assembly in human cells. EMBO Rep 7: 314-320
-
(2006)
EMBO Rep
, vol.7
, pp. 314-320
-
-
Leuschner, P.J.1
Ameres, S.L.2
Kueng, S.3
Martinez, J.4
-
102
-
-
27744506761
-
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
-
Rand TA, Petersen S, Du F, Wang X, (2005) Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell 123: 621-629
-
(2005)
Cell
, vol.123
, pp. 621-629
-
-
Rand, T.A.1
Petersen, S.2
Du, F.3
Wang, X.4
-
103
-
-
68449090733
-
C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation
-
Liu Y, Ye X, Jiang F, Liang C, Chen D, Peng J, Kinch LN, Grishin NV, Liu Q, (2009) C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation. Science 325: 750-753
-
(2009)
Science
, vol.325
, pp. 750-753
-
-
Liu, Y.1
Ye, X.2
Jiang, F.3
Liang, C.4
Chen, D.5
Peng, J.6
Kinch, L.N.7
Grishin, N.V.8
Liu, Q.9
-
104
-
-
79959366354
-
Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes
-
Gu S, Jin L, Zhang F, Huang Y, Grimm D, Rossi JJ, Kay MA, (2011) Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes. Proc Natl Acad Sci USA 108: 9208-9213
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9208-9213
-
-
Gu, S.1
Jin, L.2
Zhang, F.3
Huang, Y.4
Grimm, D.5
Rossi, J.J.6
Kay, M.A.7
-
105
-
-
34447291602
-
The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC
-
Horwich MD, Li C, Matranga C, Vagin V, Farley G, Wang P, Zamore PD, (2007) The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol 17: 1265-1272
-
(2007)
Curr Biol
, vol.17
, pp. 1265-1272
-
-
Horwich, M.D.1
Li, C.2
Matranga, C.3
Vagin, V.4
Farley, G.5
Wang, P.6
Zamore, P.D.7
-
106
-
-
77953801618
-
Target RNA-directed trimming and tailing of small silencing RNAs
-
Ameres SL, Horwich MD, Hung JH, Xu J, Ghildiyal M, Weng Z, Zamore PD, (2010) Target RNA-directed trimming and tailing of small silencing RNAs. Science 328: 1534-1539
-
(2010)
Science
, vol.328
, pp. 1534-1539
-
-
Ameres, S.L.1
Horwich, M.D.2
Hung, J.H.3
Xu, J.4
Ghildiyal, M.5
Weng, Z.6
Zamore, P.D.7
-
107
-
-
5144225452
-
Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity
-
Rand TA, Ginalski K, Grishin NV, Wang X, (2004) Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity. Proc Natl Acad Sci USA 101: 14385-14389
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14385-14389
-
-
Rand, T.A.1
Ginalski, K.2
Grishin, N.V.3
Wang, X.4
-
109
-
-
59949096548
-
Essential and overlapping functions for mammalian Argonautes in microRNA silencing
-
Su H, Trombly MI, Chen J, Wang X, (2009) Essential and overlapping functions for mammalian Argonautes in microRNA silencing. Genes Dev 23: 304-317
-
(2009)
Genes Dev
, vol.23
, pp. 304-317
-
-
Su, H.1
Trombly, M.I.2
Chen, J.3
Wang, X.4
-
110
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner G, Zamore PD, (2002) A microRNA in a multiple-turnover RNAi enzyme complex. Science 297: 2056-2060
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
111
-
-
2142654329
-
MicroRNA-directed cleavage of HOXB8 mRNA
-
Yekta S, Shih IH, Bartel DP, (2004) MicroRNA-directed cleavage of HOXB8 mRNA. Science 304: 594-596
-
(2004)
Science
, vol.304
, pp. 594-596
-
-
Yekta, S.1
Shih, I.H.2
Bartel, D.P.3
-
112
-
-
33846527241
-
Distinct populations of primary and secondary effectors during RNAi in C. Elegans
-
Pak J, Fire A, (2007) Distinct populations of primary and secondary effectors during RNAi in C. Elegans. Science 315: 241-244
-
(2007)
Science
, vol.315
, pp. 241-244
-
-
Pak, J.1
Fire, A.2
-
113
-
-
37149049127
-
In vitro analyses of the production and activity of secondary small interfering RNAs in C. Elegans
-
Aoki K, Moriguchi H, Yoshioka T, Okawa K, Tabara H, (2007) In vitro analyses of the production and activity of secondary small interfering RNAs in C. Elegans. EMBO J 26: 5007-5019
-
(2007)
EMBO J
, vol.26
, pp. 5007-5019
-
-
Aoki, K.1
Moriguchi, H.2
Yoshioka, T.3
Okawa, K.4
Tabara, H.5
-
114
-
-
33846524902
-
Secondary siRNAs result from unprimed RNA synthesis and form a distinct class
-
Sijen T, Steiner FA, Thijssen KL, Plasterk RH, (2007) Secondary siRNAs result from unprimed RNA synthesis and form a distinct class. Science 315: 244-247
-
(2007)
Science
, vol.315
, pp. 244-247
-
-
Sijen, T.1
Steiner, F.A.2
Thijssen, K.L.3
Plasterk, R.H.4
-
115
-
-
17444430392
-
MicroRNA-directed phasing during trans-acting siRNA biogenesis in plants
-
Allen E, Xie Z, Gustafson AM, Carrington JC, (2005) microRNA-directed phasing during trans-acting siRNA biogenesis in plants. Cell 121: 207-221
-
(2005)
Cell
, vol.121
, pp. 207-221
-
-
Allen, E.1
Xie, Z.2
Gustafson, A.M.3
Carrington, J.C.4
-
116
-
-
84863624978
-
C. Elegans piRNAs mediate the genome-wide surveillance of germline transcripts
-
Lee HC, Gu W, Shirayama M, Youngman E, Conte DJ, Mello CC, (2012) C. Elegans piRNAs mediate the genome-wide surveillance of germline transcripts. Cell 150: 78-87
-
(2012)
Cell
, vol.150
, pp. 78-87
-
-
Lee, H.C.1
Gu, W.2
Shirayama, M.3
Youngman, E.4
Conte, D.J.5
Mello, C.C.6
-
117
-
-
84864781042
-
Function, targets, and evolution of Caenorhabditis elegans piRNAs
-
Bagijn MP, Goldstein LD, Sapetschnig A, Weick EM, Bouasker S, Lehrbach NJ, Simard MJ, Miska EA, (2012) Function, targets, and evolution of Caenorhabditis elegans piRNAs. Science 337: 574-578
-
(2012)
Science
, vol.337
, pp. 574-578
-
-
Bagijn, M.P.1
Goldstein, L.D.2
Sapetschnig, A.3
Weick, E.M.4
Bouasker, S.5
Lehrbach, N.J.6
Simard, M.J.7
Miska, E.A.8
-
118
-
-
36749037521
-
The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race
-
Aravin AA, Hannon GJ, Brennecke J, (2007) The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science 318: 761-764
-
(2007)
Science
, vol.318
, pp. 761-764
-
-
Aravin, A.A.1
Hannon, G.J.2
Brennecke, J.3
-
119
-
-
60149098474
-
Small RNAs as guardians of the genome
-
Malone CD, Hannon GJ, (2009) Small RNAs as guardians of the genome. Cell 136: 656-668
-
(2009)
Cell
, vol.136
, pp. 656-668
-
-
Malone, C.D.1
Hannon, G.J.2
-
120
-
-
84880917068
-
PIWI-interacting RNAs: From generation to transgenerational epigenetics
-
Luteijn MJ, Ketting RF, (2013) PIWI-interacting RNAs: from generation to transgenerational epigenetics. Nat Rev Genet 14: 523-534
-
(2013)
Nat Rev Genet
, vol.14
, pp. 523-534
-
-
Luteijn, M.J.1
Ketting, R.F.2
-
121
-
-
0041941514
-
The small RNA profile during Drosophila melanogaster development
-
Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T, (2003) The small RNA profile during Drosophila melanogaster development. Dev Cell 5: 337-350
-
(2003)
Dev Cell
, vol.5
, pp. 337-350
-
-
Aravin, A.A.1
Lagos-Quintana, M.2
Yalcin, A.3
Zavolan, M.4
Marks, D.5
Snyder, B.6
Gaasterland, T.7
Meyer, J.8
Tuschl, T.9
-
122
-
-
33746502166
-
A distinct small RNA pathway silences selfish genetic elements in the germline
-
Vagin VV, Sigova A, Li C, Seitz H, Gvozdev V, Zamore PD, (2006) A distinct small RNA pathway silences selfish genetic elements in the germline. Science 313: 320-324
-
(2006)
Science
, vol.313
, pp. 320-324
-
-
Vagin, V.V.1
Sigova, A.2
Li, C.3
Seitz, H.4
Gvozdev, V.5
Zamore, P.D.6
-
123
-
-
33745402414
-
A novel class of small RNAs bind to MILI protein in mouse testes
-
Aravin A, Gaidatzis D, Pfeffer S, Lagos-Quintana M, Landgraf P, Iovino N, Morris P, Brownstein MJ, Kuramochi-Miyagawa S, Nakano T, et al (2006) A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442: 203-207
-
(2006)
Nature
, vol.442
, pp. 203-207
-
-
Aravin, A.1
Gaidatzis, D.2
Pfeffer, S.3
Lagos-Quintana, M.4
Landgraf, P.5
Iovino, N.6
Morris, P.7
Brownstein, M.J.8
Kuramochi-Miyagawa, S.9
Nakano, T.10
-
124
-
-
33745336617
-
A germline-specific class of small RNAs binds mammalian Piwi proteins
-
Girard A, Sachidanandam R, Hannon GJ, Carmell MA, (2006) A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 442: 199-202
-
(2006)
Nature
, vol.442
, pp. 199-202
-
-
Girard, A.1
Sachidanandam, R.2
Hannon, G.J.3
Carmell, M.A.4
-
125
-
-
33947273235
-
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila
-
Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ, (2007) Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 128: 1089-1103
-
(2007)
Cell
, vol.128
, pp. 1089-1103
-
-
Brennecke, J.1
Aravin, A.A.2
Stark, A.3
Dus, M.4
Kellis, M.5
Sachidanandam, R.6
Hannon, G.J.7
-
126
-
-
33947390781
-
A slicer-mediated mechanism for repeat-associated siRNA 5′end formation in Drosophila
-
Gunawardane LS, Saito K, Nishida KM, Miyoshi K, Kawamura Y, Nagami T, Siomi H, Siomi MC, (2007) A slicer-mediated mechanism for repeat-associated siRNA 5′end formation in Drosophila. Science 315: 1587-1590
-
(2007)
Science
, vol.315
, pp. 1587-1590
-
-
Gunawardane, L.S.1
Saito, K.2
Nishida, K.M.3
Miyoshi, K.4
Kawamura, Y.5
Nagami, T.6
Siomi, H.7
Siomi, M.C.8
-
127
-
-
34047154356
-
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish
-
Houwing S, Kamminga LM, Berezikov E, Cronembold D, Girard A, van den Elst H, Filippov DV, Blaser H, Raz E, Moens CB, et al (2007) A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell 129: 69-82
-
(2007)
Cell
, vol.129
, pp. 69-82
-
-
Houwing, S.1
Kamminga, L.M.2
Berezikov, E.3
Cronembold, D.4
Girard, A.5
Van Den Elst, H.6
Filippov, D.V.7
Blaser, H.8
Raz, E.9
Moens, C.B.10
-
128
-
-
84891923717
-
Homeland security in the germ line: Insights into the biogenesis and function of piRNAs
-
Kasper DM, Gardner KE, Reinke V, (2013) Homeland security in the germ line: insights into the biogenesis and function of piRNAs. Epigenetics 9: 62-74
-
(2013)
Epigenetics
, vol.9
, pp. 62-74
-
-
Kasper, D.M.1
Gardner, K.E.2
Reinke, V.3
-
129
-
-
33947720638
-
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline
-
Carmell MA, Girard A, van de Kant HJ, Bourc'is D, Bestor TH, de Rooij DG, Hannon GJ, (2007) MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell 12: 503-514
-
(2007)
Dev Cell
, vol.12
, pp. 503-514
-
-
Carmell, M.A.1
Girard, A.2
Van De Kant, H.J.3
Bourc'Is, D.4
Bestor, T.H.5
De Rooij, D.G.6
Hannon, G.J.7
-
130
-
-
34248160438
-
Developmentally regulated piRNA clusters implicate MILI in transposon control
-
Aravin AA, Sachidanandam R, Girard A, Fejes-Toth K, Hannon GJ, (2007) Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 316: 744-747
-
(2007)
Science
, vol.316
, pp. 744-747
-
-
Aravin, A.A.1
Sachidanandam, R.2
Girard, A.3
Fejes-Toth, K.4
Hannon, G.J.5
-
131
-
-
17144417381
-
Argonaute protein PIWI controls mobilization of retrotransposons in the Drosophila male germline
-
Kalmykova AI, Klenov MS, Gvozdev VA, (2005) Argonaute protein PIWI controls mobilization of retrotransposons in the Drosophila male germline. Nucleic Acids Res 33: 2052-2059
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2052-2059
-
-
Kalmykova, A.I.1
Klenov, M.S.2
Gvozdev, V.A.3
-
132
-
-
33947641533
-
Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila
-
Chen Y, Pane A, Schupbach T, (2007) Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila. Curr Biol 17: 637-642
-
(2007)
Curr Biol
, vol.17
, pp. 637-642
-
-
Chen, Y.1
Pane, A.2
Schupbach, T.3
-
133
-
-
84876070120
-
An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes
-
Li XZ, Roy CK, Dong X, Bolcun-Filas E, Wang J, Han BW, Xu J, Moore MJ, Schimenti JC, Weng Z, et al (2013) An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Mol Cell 50: 67-81
-
(2013)
Mol Cell
, vol.50
, pp. 67-81
-
-
Li, X.Z.1
Roy, C.K.2
Dong, X.3
Bolcun-Filas, E.4
Wang, J.5
Han, B.W.6
Xu, J.7
Moore, M.J.8
Schimenti, J.C.9
Weng, Z.10
-
134
-
-
78149478349
-
Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila
-
Saito K, Ishizu H, Komai M, Kotani H, Kawamura Y, Nishida KM, Siomi H, Siomi MC, (2010) Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila. Genes Dev 24: 2493-2498
-
(2010)
Genes Dev
, vol.24
, pp. 2493-2498
-
-
Saito, K.1
Ishizu, H.2
Komai, M.3
Kotani, H.4
Kawamura, Y.5
Nishida, K.M.6
Siomi, H.7
Siomi, M.C.8
-
135
-
-
77957793321
-
An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila
-
Olivieri D, Sykora MM, Sachidanandam R, Mechtler K, Brennecke J, (2010) An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila. EMBO J 29: 3301-3317
-
(2010)
EMBO J
, vol.29
, pp. 3301-3317
-
-
Olivieri, D.1
Sykora, M.M.2
Sachidanandam, R.3
Mechtler, K.4
Brennecke, J.5
-
136
-
-
79952525007
-
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline
-
Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, et al (2011) MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell 20: 364-375
-
(2011)
Dev Cell
, vol.20
, pp. 364-375
-
-
Watanabe, T.1
Chuma, S.2
Yamamoto, Y.3
Kuramochi-Miyagawa, S.4
Totoki, Y.5
Toyoda, A.6
Hoki, Y.7
Fujiyama, A.8
Shibata, T.9
Sado, T.10
-
137
-
-
84868626090
-
Structure and function of Zucchini endoribonuclease in piRNA biogenesis
-
Nishimasu H, Ishizu H, Saito K, Fukuhara S, Kamatani MK, Bonnefond L, Matsumoto N, Nishizawa T, Nakanaga K, Aoki J, et al (2012) Structure and function of Zucchini endoribonuclease in piRNA biogenesis. Nature 491: 284-287
-
(2012)
Nature
, vol.491
, pp. 284-287
-
-
Nishimasu, H.1
Ishizu, H.2
Saito, K.3
Fukuhara, S.4
Kamatani, M.K.5
Bonnefond, L.6
Matsumoto, N.7
Nishizawa, T.8
Nakanaga, K.9
Aoki, J.10
-
138
-
-
84868613084
-
The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis
-
Ipsaro JJ, Haase AD, Knott SR, Joshua-Tor L, Hannon GJ, (2012) The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature 491: 279-283
-
(2012)
Nature
, vol.491
, pp. 279-283
-
-
Ipsaro, J.J.1
Haase, A.D.2
Knott, S.R.3
Joshua-Tor, L.4
Hannon, G.J.5
-
139
-
-
84878827621
-
The genetic makeup of the Drosophila piRNA pathway
-
Handler D, Meixner K, Pizka M, Lauss K, Schmied C, Gruber FS, Brennecke J, (2013) The genetic makeup of the Drosophila piRNA pathway. Mol Cell 50: 762-777
-
(2013)
Mol Cell
, vol.50
, pp. 762-777
-
-
Handler, D.1
Meixner, K.2
Pizka, M.3
Lauss, K.4
Schmied, C.5
Gruber, F.S.6
Brennecke, J.7
-
140
-
-
84878851966
-
A transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway
-
Czech B, Preall JB, McGinn J, Hannon GJ, (2013) A transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway. Mol Cell 50: 749-761
-
(2013)
Mol Cell
, vol.50
, pp. 749-761
-
-
Czech, B.1
Preall, J.B.2
McGinn, J.3
Hannon, G.J.4
-
141
-
-
69249225196
-
The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters
-
Klattenhoff C, Xi H, Li C, Lee S, Xu J, Khurana JS, Zhang F, Schultz N, Koppetsch BS, Nowosielska A, et al (2009) The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters. Cell 138: 1137-1149
-
(2009)
Cell
, vol.138
, pp. 1137-1149
-
-
Klattenhoff, C.1
Xi, H.2
Li, C.3
Lee, S.4
Xu, J.5
Khurana, J.S.6
Zhang, F.7
Schultz, N.8
Koppetsch, B.S.9
Nowosielska, A.10
-
142
-
-
84869016142
-
UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery
-
Zhang F, Wang J, Xu J, Zhang Z, Koppetsch BS, Schultz N, Vreven T, Meignin C, Davis I, Zamore PD, et al (2012) UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell 151: 871-884
-
(2012)
Cell
, vol.151
, pp. 871-884
-
-
Zhang, F.1
Wang, J.2
Xu, J.3
Zhang, Z.4
Koppetsch, B.S.5
Schultz, N.6
Vreven, T.7
Meignin, C.8
Davis, I.9
Zamore, P.D.10
-
143
-
-
34249849029
-
Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster
-
Lim AK, Kai T, (2007) Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster. Proc Natl Acad Sci USA 104: 6714-6719
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 6714-6719
-
-
Lim, A.K.1
Kai, T.2
-
144
-
-
0035960716
-
MRNA export: Travelling with DEAD box proteins
-
Linder P, Stutz F, (2001) mRNA export: travelling with DEAD box proteins. Curr Biol 11: R961-R963
-
(2001)
Curr Biol
, vol.11
-
-
Linder, P.1
Stutz, F.2
-
145
-
-
84866285309
-
Promoters recognized by forkhead proteins exist for individual 21U-RNAs
-
Cecere G, Zheng GX, Mansisidor AR, Klymko KE, Grishok A, (2012) Promoters recognized by forkhead proteins exist for individual 21U-RNAs. Mol Cell 47: 734-745
-
(2012)
Mol Cell
, vol.47
, pp. 734-745
-
-
Cecere, G.1
Zheng, G.X.2
Mansisidor, A.R.3
Klymko, K.E.4
Grishok, A.5
-
146
-
-
84898661166
-
Transcriptional properties and splicing of the flamenco piRNA cluster
-
doi: 10.1002/embr.201337898
-
Goriaux C, Desset S, Renaud Y, Vaury C, Brasset E, (2014) Transcriptional properties and splicing of the flamenco piRNA cluster. EMBO Rep doi: 10.1002/embr.201337898
-
(2014)
EMBO Rep
-
-
Goriaux, C.1
Desset, S.2
Renaud, Y.3
Vaury, C.4
Brasset, E.5
-
147
-
-
70449519397
-
A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila
-
Saito K, Inagaki S, Mituyama T, Kawamura Y, Ono Y, Sakota E, Kotani H, Asai K, Siomi H, Siomi MC, (2009) A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila. Nature 461: 1296-1299
-
(2009)
Nature
, vol.461
, pp. 1296-1299
-
-
Saito, K.1
Inagaki, S.2
Mituyama, T.3
Kawamura, Y.4
Ono, Y.5
Sakota, E.6
Kotani, H.7
Asai, K.8
Siomi, H.9
Siomi, M.C.10
-
148
-
-
72649094955
-
A broadly conserved pathway generates 3′UTR-directed primary piRNAs
-
Robine N, Lau NC, Balla S, Jin Z, Okamura K, Kuramochi-Miyagawa S, Blower MD, Lai EC, (2009) A broadly conserved pathway generates 3′UTR-directed primary piRNAs. Curr Biol 19: 2066-2076
-
(2009)
Curr Biol
, vol.19
, pp. 2066-2076
-
-
Robine, N.1
Lau, N.C.2
Balla, S.3
Jin, Z.4
Okamura, K.5
Kuramochi-Miyagawa, S.6
Blower, M.D.7
Lai, E.C.8
-
149
-
-
84879414849
-
Argonaute proteins: Functional insights and emerging roles
-
Meister G, (2013) Argonaute proteins: functional insights and emerging roles. Nat Rev Genet 14: 447-459
-
(2013)
Nat Rev Genet
, vol.14
, pp. 447-459
-
-
Meister, G.1
-
150
-
-
80052991624
-
3′end formation of PIWI-interacting RNAs in vitro
-
Kawaoka S, Izumi N, Katsuma S, Tomari Y, (2011) 3′end formation of PIWI-interacting RNAs in vitro. Mol Cell 43: 1015-1022
-
(2011)
Mol Cell
, vol.43
, pp. 1015-1022
-
-
Kawaoka, S.1
Izumi, N.2
Katsuma, S.3
Tomari, Y.4
-
151
-
-
84884681157
-
Mitochondrial protein BmPAPI modulates the length of mature piRNAs
-
Honda S, Kirino Y, Maragkakis M, Alexiou P, Ohtaki A, Murali R, Mourelatos Z, Kirino Y, (2013) Mitochondrial protein BmPAPI modulates the length of mature piRNAs. RNA 19: 1405-1418
-
(2013)
RNA
, vol.19
, pp. 1405-1418
-
-
Honda, S.1
Kirino, Y.2
Maragkakis, M.3
Alexiou, P.4
Ohtaki, A.5
Murali, R.6
Mourelatos, Z.7
Kirino, Y.8
-
152
-
-
84880220867
-
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline
-
Saxe JP, Chen M, Zhao H, Lin H, (2013) Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J 32: 1869-1885
-
(2013)
EMBO J
, vol.32
, pp. 1869-1885
-
-
Saxe, J.P.1
Chen, M.2
Zhao, H.3
Lin, H.4
-
153
-
-
34548366485
-
The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs
-
Kirino Y, Mourelatos Z, (2007) The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs. RNA 13: 1397-1401
-
(2007)
RNA
, vol.13
, pp. 1397-1401
-
-
Kirino, Y.1
Mourelatos, Z.2
-
154
-
-
34347378274
-
Pimet, the Drosophila homolog of HEN1, mediates 2′O-methylation of Piwi-interacting RNAs at their 3′ends
-
Saito K, Sakaguchi Y, Suzuki T, Suzuki T, Siomi H, Siomi MC, (2007) Pimet, the Drosophila homolog of HEN1, mediates 2′O-methylation of Piwi-interacting RNAs at their 3′ends. Genes Dev 21: 1603-1608
-
(2007)
Genes Dev
, vol.21
, pp. 1603-1608
-
-
Saito, K.1
Sakaguchi, Y.2
Suzuki, T.3
Suzuki, T.4
Siomi, H.5
Siomi, M.C.6
-
155
-
-
33747369856
-
Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome
-
Saito K, Nishida KM, Mori T, Kawamura Y, Miyoshi K, Nagami T, Siomi H, Siomi MC, (2006) Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev 20: 2214-2222
-
(2006)
Genes Dev
, vol.20
, pp. 2214-2222
-
-
Saito, K.1
Nishida, K.M.2
Mori, T.3
Kawamura, Y.4
Miyoshi, K.5
Nagami, T.6
Siomi, H.7
Siomi, M.C.8
-
156
-
-
77951804331
-
MVH in piRNA processing and gene silencing of retrotransposons
-
Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, et al (2010) MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev 24: 887-892
-
(2010)
Genes Dev
, vol.24
, pp. 887-892
-
-
Kuramochi-Miyagawa, S.1
Watanabe, T.2
Gotoh, K.3
Takamatsu, K.4
Chuma, S.5
Kojima-Kita, K.6
Shiromoto, Y.7
Asada, N.8
Toyoda, A.9
Fujiyama, A.10
-
157
-
-
77950488501
-
How does the royal family of Tudor rule the PIWI-interacting RNA pathway?
-
Siomi MC, Mannen T, Siomi H, (2010) How does the royal family of Tudor rule the PIWI-interacting RNA pathway? Genes Dev 24: 636-646
-
(2010)
Genes Dev
, vol.24
, pp. 636-646
-
-
Siomi, M.C.1
Mannen, T.2
Siomi, H.3
-
158
-
-
34548784928
-
Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline
-
Klenov MS, Lavrov SA, Stolyarenko AD, Ryazansky SS, Aravin AA, Tuschl T, Gvozdev VA, (2007) Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline. Nucleic Acids Res 35: 5430-5438
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5430-5438
-
-
Klenov, M.S.1
Lavrov, S.A.2
Stolyarenko, A.D.3
Ryazansky, S.S.4
Aravin, A.A.5
Tuschl, T.6
Gvozdev, V.A.7
-
159
-
-
80455178787
-
Mechanism of the piRNA-mediated silencing of Drosophila telomeric retrotransposons
-
Shpiz S, Olovnikov I, Sergeeva A, Lavrov S, Abramov Y, Savitsky M, Kalmykova A, (2011) Mechanism of the piRNA-mediated silencing of Drosophila telomeric retrotransposons. Nucleic Acids Res 39: 8703-8711
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 8703-8711
-
-
Shpiz, S.1
Olovnikov, I.2
Sergeeva, A.3
Lavrov, S.4
Abramov, Y.5
Savitsky, M.6
Kalmykova, A.7
-
160
-
-
84862907807
-
Drosophila Piwi functions downstream of piRNA production mediating a chromatin-based transposon silencing mechanism in female germ line
-
Wang SH, Elgin SC, (2011) Drosophila Piwi functions downstream of piRNA production mediating a chromatin-based transposon silencing mechanism in female germ line. Proc Natl Acad Sci USA 108: 21164-21169
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 21164-21169
-
-
Wang, S.H.1
Elgin, S.C.2
-
161
-
-
84870060785
-
Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression
-
Sienski G, Donertas D, Brennecke J, (2012) Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression. Cell 151: 964-980
-
(2012)
Cell
, vol.151
, pp. 964-980
-
-
Sienski, G.1
Donertas, D.2
Brennecke, J.3
-
162
-
-
52049098967
-
A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice
-
Aravin AA, Sachidanandam R, Bourc'is D, Schaefer C, Pezic D, Toth KF, Bestor T, Hannon GJ, (2008) A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell 31: 785-799
-
(2008)
Mol Cell
, vol.31
, pp. 785-799
-
-
Aravin, A.A.1
Sachidanandam, R.2
Bourc'Is, D.3
Schaefer, C.4
Pezic, D.5
Toth, K.F.6
Bestor, T.7
Hannon, G.J.8
-
163
-
-
41649116098
-
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes
-
Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M, Asada N, Kojima K, Yamaguchi Y, Ijiri TW, et al (2008) DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev 22: 908-917
-
(2008)
Genes Dev
, vol.22
, pp. 908-917
-
-
Kuramochi-Miyagawa, S.1
Watanabe, T.2
Gotoh, K.3
Totoki, Y.4
Toyoda, A.5
Ikawa, M.6
Asada, N.7
Kojima, K.8
Yamaguchi, Y.9
Ijiri, T.W.10
-
164
-
-
0033966406
-
Piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells
-
Cox DN, Chao A, Lin H, (2000) piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells. Development 127: 503-514
-
(2000)
Development
, vol.127
, pp. 503-514
-
-
Cox, D.N.1
Chao, A.2
Lin, H.3
-
165
-
-
0942279615
-
Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery
-
Pal-Bhadra M, Leibovitch BA, Gandhi SG, Chikka MR, Bhadra U, Birchler JA, Elgin SC, (2004) Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science 303: 669-672
-
(2004)
Science
, vol.303
, pp. 669-672
-
-
Pal-Bhadra, M.1
Leibovitch, B.A.2
Gandhi, S.G.3
Chikka, M.R.4
Bhadra, U.5
Birchler, J.A.6
Elgin, S.C.7
-
166
-
-
34548822460
-
Drosophila PIWI associates with chromatin and interacts directly with HP1a
-
Brower-Toland B, Findley SD, Jiang L, Liu L, Yin H, Dus M, Zhou P, Elgin SC, Lin H, (2007) Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev 21: 2300-2311
-
(2007)
Genes Dev
, vol.21
, pp. 2300-2311
-
-
Brower-Toland, B.1
Findley, S.D.2
Jiang, L.3
Liu, L.4
Yin, H.5
Dus, M.6
Zhou, P.7
Elgin, S.C.8
Lin, H.9
-
167
-
-
84881045635
-
DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary
-
Ohtani H, Iwasaki YW, Shibuya A, Siomi H, Siomi MC, Saito K, (2013) DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary. Genes Dev 27: 1656-1661
-
(2013)
Genes Dev
, vol.27
, pp. 1656-1661
-
-
Ohtani, H.1
Iwasaki, Y.W.2
Shibuya, A.3
Siomi, H.4
Siomi, M.C.5
Saito, K.6
-
168
-
-
84881081955
-
Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex
-
Donertas D, Sienski G, Brennecke J, (2013) Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex. Genes Dev 27: 1693-1705
-
(2013)
Genes Dev
, vol.27
, pp. 1693-1705
-
-
Donertas, D.1
Sienski, G.2
Brennecke, J.3
-
169
-
-
84878847013
-
A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila
-
Muerdter F, Guzzardo PM, Gillis J, Luo Y, Yu Y, Chen C, Fekete R, Hannon GJ, (2013) A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila. Mol Cell 50: 736-748
-
(2013)
Mol Cell
, vol.50
, pp. 736-748
-
-
Muerdter, F.1
Guzzardo, P.M.2
Gillis, J.3
Luo, Y.4
Yu, Y.5
Chen, C.6
Fekete, R.7
Hannon, G.J.8
-
170
-
-
79956157571
-
Evolution and classification of the CRISPR-Cas systems
-
Makarova KS, Haft DH, Barrangou R, Brouns SJ, Charpentier E, Horvath P, Moineau S, Mojica FJ, Wolf YI, Yakunin AF, et al (2011) Evolution and classification of the CRISPR-Cas systems. Nat Rev Microbiol 9: 467-477
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 467-477
-
-
Makarova, K.S.1
Haft, D.H.2
Barrangou, R.3
Brouns, S.J.4
Charpentier, E.5
Horvath, P.6
Moineau, S.7
Mojica, F.J.8
Wolf, Y.I.9
Yakunin, A.F.10
-
171
-
-
74249095519
-
CRISPR/Cas, the immune system of bacteria and archaea
-
Horvath P, Barrangou R, (2010) CRISPR/Cas, the immune system of bacteria and archaea. Science 327: 167-170
-
(2010)
Science
, vol.327
, pp. 167-170
-
-
Horvath, P.1
Barrangou, R.2
-
172
-
-
0036267740
-
Identification of genes that are associated with DNA repeats in prokaryotes
-
Jansen R, Embden JD, Gaastra W, Schouls LM, (2002) Identification of genes that are associated with DNA repeats in prokaryotes. Mol Microbiol 43: 1565-1575
-
(2002)
Mol Microbiol
, vol.43
, pp. 1565-1575
-
-
Jansen, R.1
Embden, J.D.2
Gaastra, W.3
Schouls, L.M.4
-
173
-
-
23844505202
-
Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin
-
Bolotin A, Quinquis B, Sorokin A, Ehrlich SD, (2005) Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin. Microbiology 151: 2551-2561
-
(2005)
Microbiology
, vol.151
, pp. 2551-2561
-
-
Bolotin, A.1
Quinquis, B.2
Sorokin, A.3
Ehrlich, S.D.4
-
174
-
-
16444385662
-
Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements
-
Mojica FJ, Diez-Villasenor C, Garcia-Martinez J, Soria E, (2005) Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements. J Mol Evol 60: 174-182
-
(2005)
J Mol Evol
, vol.60
, pp. 174-182
-
-
Mojica, F.J.1
Diez-Villasenor, C.2
Garcia-Martinez, J.3
Soria, E.4
-
175
-
-
15844390228
-
CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies
-
Pourcel C, Salvignol G, Vergnaud G, (2005) CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies. Microbiology 151: 653-663
-
(2005)
Microbiology
, vol.151
, pp. 653-663
-
-
Pourcel, C.1
Salvignol, G.2
Vergnaud, G.3
-
176
-
-
64049118040
-
Short motif sequences determine the targets of the prokaryotic CRISPR defence system
-
Mojica FJ, Diez-Villasenor C, Garcia-Martinez J, Almendros C, (2009) Short motif sequences determine the targets of the prokaryotic CRISPR defence system. Microbiology 155: 733-740
-
(2009)
Microbiology
, vol.155
, pp. 733-740
-
-
Mojica, F.J.1
Diez-Villasenor, C.2
Garcia-Martinez, J.3
Almendros, C.4
-
177
-
-
38949214103
-
Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus
-
Horvath P, Romero DA, Coute-Monvoisin AC, Richards M, Deveau H, Moineau S, Boyaval P, Fremaux C, Barrangou R, (2008) Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus. J Bacteriol 190: 1401-1412
-
(2008)
J Bacteriol
, vol.190
, pp. 1401-1412
-
-
Horvath, P.1
Romero, D.A.2
Coute-Monvoisin, A.C.3
Richards, M.4
Deveau, H.5
Moineau, S.6
Boyaval, P.7
Fremaux, C.8
Barrangou, R.9
-
178
-
-
78149261827
-
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
-
Garneau JE, Dupuis ME, Villion M, Romero DA, Barrangou R, Boyaval P, Fremaux C, Horvath P, Magadan AH, Moineau S, (2010) The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature 468: 67-71
-
(2010)
Nature
, vol.468
, pp. 67-71
-
-
Garneau, J.E.1
Dupuis, M.E.2
Villion, M.3
Romero, D.A.4
Barrangou, R.5
Boyaval, P.6
Fremaux, C.7
Horvath, P.8
Magadan, A.H.9
Moineau, S.10
-
179
-
-
34047118522
-
CRISPR provides acquired resistance against viruses in prokaryotes
-
Barrangou R, Fremaux C, Deveau H, Richards M, Boyaval P, Moineau S, Romero DA, Horvath P, (2007) CRISPR provides acquired resistance against viruses in prokaryotes. Science 315: 1709-1712
-
(2007)
Science
, vol.315
, pp. 1709-1712
-
-
Barrangou, R.1
Fremaux, C.2
Deveau, H.3
Richards, M.4
Boyaval, P.5
Moineau, S.6
Romero, D.A.7
Horvath, P.8
-
180
-
-
84864864464
-
Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system
-
Datsenko KA, Pougach K, Tikhonov A, Wanner BL, Severinov K, Semenova E, (2012) Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system. Nat Commun 3: 945
-
(2012)
Nat Commun
, vol.3
, pp. 945
-
-
Datsenko, K.A.1
Pougach, K.2
Tikhonov, A.3
Wanner, B.L.4
Severinov, K.5
Semenova, E.6
-
181
-
-
77956628107
-
Transcription, processing and function of CRISPR cassettes in Escherichia coli
-
Pougach K, Semenova E, Bogdanova E, Datsenko KA, Djordjevic M, Wanner BL, Severinov K, (2010) Transcription, processing and function of CRISPR cassettes in Escherichia coli. Mol Microbiol 77: 1367-1379
-
(2010)
Mol Microbiol
, vol.77
, pp. 1367-1379
-
-
Pougach, K.1
Semenova, E.2
Bogdanova, E.3
Datsenko, K.A.4
Djordjevic, M.5
Wanner, B.L.6
Severinov, K.7
-
182
-
-
57849137502
-
CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA
-
Marraffini LA, Sontheimer EJ, (2008) CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA. Science 322: 1843-1845
-
(2008)
Science
, vol.322
, pp. 1843-1845
-
-
Marraffini, L.A.1
Sontheimer, E.J.2
-
183
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E, (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337: 816-821
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
184
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM, (2013) RNA-guided human genome engineering via Cas9. Science 339: 823-826
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
Dicarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
185
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, et al (2013) Multiplex genome engineering using CRISPR/Cas systems. Science 339: 819-823
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
-
186
-
-
84884856342
-
Cas9 as a versatile tool for engineering biology
-
Mali P, Esvelt KM, Church GM, (2013) Cas9 as a versatile tool for engineering biology. Nat Methods 10: 957-963
-
(2013)
Nat Methods
, vol.10
, pp. 957-963
-
-
Mali, P.1
Esvelt, K.M.2
Church, G.M.3
-
187
-
-
49649114086
-
Small CRISPR RNAs guide antiviral defense in prokaryotes
-
Brouns SJ, Jore MM, Lundgren M, Westra ER, Slijkhuis RJ, Snijders AP, Dickman MJ, Makarova KS, Koonin EV, van der Oost J, (2008) Small CRISPR RNAs guide antiviral defense in prokaryotes. Science 321: 960-964
-
(2008)
Science
, vol.321
, pp. 960-964
-
-
Brouns, S.J.1
Jore, M.M.2
Lundgren, M.3
Westra, E.R.4
Slijkhuis, R.J.5
Snijders, A.P.6
Dickman, M.J.7
Makarova, K.S.8
Koonin, E.V.9
Van Der Oost, J.10
-
188
-
-
77956498326
-
Sequence- and structure-specific RNA processing by a CRISPR endonuclease
-
Haurwitz RE, Jinek M, Wiedenheft B, Zhou K, Doudna JA, (2010) Sequence- and structure-specific RNA processing by a CRISPR endonuclease. Science 329: 1355-1358
-
(2010)
Science
, vol.329
, pp. 1355-1358
-
-
Haurwitz, R.E.1
Jinek, M.2
Wiedenheft, B.3
Zhou, K.4
Doudna, J.A.5
-
189
-
-
79958848350
-
Recognition and maturation of effector RNAs in a CRISPR interference pathway
-
Gesner EM, Schellenberg MJ, Garside EL, George MM, Macmillan AM, (2011) Recognition and maturation of effector RNAs in a CRISPR interference pathway. Nat Struct Mol Biol 18: 688-692
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 688-692
-
-
Gesner, E.M.1
Schellenberg, M.J.2
Garside, E.L.3
George, M.M.4
MacMillan, A.M.5
-
190
-
-
58049191229
-
Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes
-
Carte J, Wang R, Li H, Terns RM, Terns MP, (2008) Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes. Genes Dev 22: 3489-3496
-
(2008)
Genes Dev
, vol.22
, pp. 3489-3496
-
-
Carte, J.1
Wang, R.2
Li, H.3
Terns, R.M.4
Terns, M.P.5
-
191
-
-
78149355930
-
Binding and cleavage of CRISPR RNA by Cas6
-
Carte J, Pfister NT, Compton MM, Terns RM, Terns MP, (2010) Binding and cleavage of CRISPR RNA by Cas6. RNA 16: 2181-2188
-
(2010)
RNA
, vol.16
, pp. 2181-2188
-
-
Carte, J.1
Pfister, N.T.2
Compton, M.M.3
Terns, R.M.4
Terns, M.P.5
-
192
-
-
79953250082
-
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
-
Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E, (2011) CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature 471: 602-607
-
(2011)
Nature
, vol.471
, pp. 602-607
-
-
Deltcheva, E.1
Chylinski, K.2
Sharma, C.M.3
Gonzales, K.4
Chao, Y.5
Pirzada, Z.A.6
Eckert, M.R.7
Vogel, J.8
Charpentier, E.9
-
193
-
-
79959963663
-
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
-
Semenova E, Jore MM, Datsenko KA, Semenova A, Westra ER, Wanner B, van der Oost J, Brouns SJ, Severinov K, (2011) Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence. Proc Natl Acad Sci USA 108: 10098-10103
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 10098-10103
-
-
Semenova, E.1
Jore, M.M.2
Datsenko, K.A.3
Semenova, A.4
Westra, E.R.5
Wanner, B.6
Van Der Oost, J.7
Brouns, S.J.8
Severinov, K.9
-
194
-
-
79955574254
-
Structural basis for CRISPR RNA-guided DNA recognition by Cascade
-
Jore MM, Lundgren M, van Duijn E, Bultema JB, Westra ER, Waghmare SP, Wiedenheft B, Pul U, Wurm R, Wagner R, et al (2011) Structural basis for CRISPR RNA-guided DNA recognition by Cascade. Nat Struct Mol Biol 18: 529-536
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 529-536
-
-
Jore, M.M.1
Lundgren, M.2
Van Duijn, E.3
Bultema, J.B.4
Westra, E.R.5
Waghmare, S.P.6
Wiedenheft, B.7
Pul, U.8
Wurm, R.9
Wagner, R.10
-
195
-
-
81255160844
-
Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference
-
Beloglazova N, Petit P, Flick R, Brown G, Savchenko A, Yakunin AF, (2011) Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference. EMBO J 30: 4616-4627
-
(2011)
EMBO J
, vol.30
, pp. 4616-4627
-
-
Beloglazova, N.1
Petit, P.2
Flick, R.3
Brown, G.4
Savchenko, A.5
Yakunin, A.F.6
-
196
-
-
79953779608
-
Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system
-
Sinkunas T, Gasiunas G, Fremaux C, Barrangou R, Horvath P, Siksnys V, (2011) Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system. EMBO J 30: 1335-1342
-
(2011)
EMBO J
, vol.30
, pp. 1335-1342
-
-
Sinkunas, T.1
Gasiunas, G.2
Fremaux, C.3
Barrangou, R.4
Horvath, P.5
Siksnys, V.6
-
197
-
-
84866859751
-
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
-
Gasiunas G, Barrangou R, Horvath P, Siksnys V, (2012) Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc Natl Acad Sci USA 109: E2579-E2586
-
(2012)
Proc Natl Acad Sci USA
, vol.109
-
-
Gasiunas, G.1
Barrangou, R.2
Horvath, P.3
Siksnys, V.4
-
198
-
-
84890935599
-
Genetic characterization of anti-plasmid immunity by a Type III-A CRISPR-Cas system
-
doi: 10.1128/JB.01130-13
-
Hatoum-Aslan A, Maniv I, Samai P, Marraffini LA, (2013) Genetic characterization of anti-plasmid immunity by a Type III-A CRISPR-Cas system. J Bacteriol doi: 10.1128/JB.01130-13
-
(2013)
J Bacteriol
-
-
Hatoum-Aslan, A.1
Maniv, I.2
Samai, P.3
Marraffini, L.A.4
-
199
-
-
70449753811
-
RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex
-
Hale CR, Zhao P, Olson S, Duff MO, Graveley BR, Wells L, Terns RM, Terns MP, (2009) RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex. Cell 139: 945-956
-
(2009)
Cell
, vol.139
, pp. 945-956
-
-
Hale, C.R.1
Zhao, P.2
Olson, S.3
Duff, M.O.4
Graveley, B.R.5
Wells, L.6
Terns, R.M.7
Terns, M.P.8
-
200
-
-
84856792673
-
Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNAs
-
Hale CR, Majumdar S, Elmore J, Pfister N, Compton M, Olson S, Resch AM, Glover CV, Graveley BR, Terns RM, et al (2012) Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNAs. Mol Cell 45: 292-302
-
(2012)
Mol Cell
, vol.45
, pp. 292-302
-
-
Hale, C.R.1
Majumdar, S.2
Elmore, J.3
Pfister, N.4
Compton, M.5
Olson, S.6
Resch, A.M.7
Glover, C.V.8
Graveley, B.R.9
Terns, R.M.10
-
201
-
-
62549134121
-
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
-
Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS, (2009) Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 324: 218-223
-
(2009)
Science
, vol.324
, pp. 218-223
-
-
Ingolia, N.T.1
Ghaemmaghami, S.2
Newman, J.R.3
Weissman, J.S.4
-
202
-
-
81055155799
-
Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes
-
Ingolia NT, Lareau LF, Weissman JS, (2011) Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell 147: 789-802
-
(2011)
Cell
, vol.147
, pp. 789-802
-
-
Ingolia, N.T.1
Lareau, L.F.2
Weissman, J.S.3
-
203
-
-
34249021370
-
Peptides encoded by short ORFs control development and define a new eukaryotic gene family
-
Galindo MI, Pueyo JI, Fouix S, Bishop SA, Couso JP, (2007) Peptides encoded by short ORFs control development and define a new eukaryotic gene family. PLoS Biol 5: e106
-
(2007)
PLoS Biol
, vol.5
-
-
Galindo, M.I.1
Pueyo, J.I.2
Fouix, S.3
Bishop, S.A.4
Couso, J.P.5
-
204
-
-
33746736922
-
A segmentation gene in tribolium produces a polycistronic mRNA that codes for multiple conserved peptides
-
Savard J, Marques-Souza H, Aranda M, Tautz D, (2006) A segmentation gene in tribolium produces a polycistronic mRNA that codes for multiple conserved peptides. Cell 126: 559-569
-
(2006)
Cell
, vol.126
, pp. 559-569
-
-
Savard, J.1
Marques-Souza, H.2
Aranda, M.3
Tautz, D.4
-
205
-
-
34447573973
-
Small peptide regulators of actin-based cell morphogenesis encoded by a polycistronic mRNA
-
Kondo T, Hashimoto Y, Kato K, Inagaki S, Hayashi S, Kageyama Y, (2007) Small peptide regulators of actin-based cell morphogenesis encoded by a polycistronic mRNA. Nat Cell Biol 9: 660-665
-
(2007)
Nat Cell Biol
, vol.9
, pp. 660-665
-
-
Kondo, T.1
Hashimoto, Y.2
Kato, K.3
Inagaki, S.4
Hayashi, S.5
Kageyama, Y.6
-
206
-
-
84891749518
-
Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors
-
Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, et al (2014) Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors. Science 343: 1248636
-
(2014)
Science
, vol.343
, pp. 1248636
-
-
Pauli, A.1
Norris, M.L.2
Valen, E.3
Chew, G.L.4
Gagnon, J.A.5
Zimmerman, S.6
Mitchell, A.7
Ma, J.8
Dubrulle, J.9
Reyon, D.10
-
207
-
-
84879969127
-
Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins
-
Guttman M, Russell P, Ingolia NT, Weissman JS, Lander ES, (2013) Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. Cell 154: 240-251
-
(2013)
Cell
, vol.154
, pp. 240-251
-
-
Guttman, M.1
Russell, P.2
Ingolia, N.T.3
Weissman, J.S.4
Lander, E.S.5
-
208
-
-
84865727393
-
The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
-
Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, Guernec G, Martin D, Merkel A, Knowles DG, et al (2012) The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res 22: 1775-1789
-
(2012)
Genome Res
, vol.22
, pp. 1775-1789
-
-
Derrien, T.1
Johnson, R.2
Bussotti, G.3
Tanzer, A.4
Djebali, S.5
Tilgner, H.6
Guernec, G.7
Martin, D.8
Merkel, A.9
Knowles, D.G.10
-
209
-
-
84875418596
-
Noncoding RNA and Polycomb recruitment
-
Brockdorff N, (2013) Noncoding RNA and Polycomb recruitment. RNA 19: 429-442
-
(2013)
RNA
, vol.19
, pp. 429-442
-
-
Brockdorff, N.1
-
210
-
-
84883816842
-
Guided by RNAs: X-inactivation as a model for lncRNA function
-
Froberg JE, Yang L, Lee JT, (2013) Guided by RNAs: X-inactivation as a model for lncRNA function. J Mol Biol 425: 3698-3706
-
(2013)
J Mol Biol
, vol.425
, pp. 3698-3706
-
-
Froberg, J.E.1
Yang, L.2
Lee, J.T.3
-
211
-
-
84861904178
-
Genome regulation by long noncoding RNAs
-
Rinn JL, Chang HY, (2012) Genome regulation by long noncoding RNAs. Annu Rev Biochem 81: 145-166
-
(2012)
Annu Rev Biochem
, vol.81
, pp. 145-166
-
-
Rinn, J.L.1
Chang, H.Y.2
-
212
-
-
77954572735
-
Long noncoding RNA as modular scaffold of histone modification complexes
-
Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, Shi Y, Segal E, Chang HY, (2010) Long noncoding RNA as modular scaffold of histone modification complexes. Science 329: 689-693
-
(2010)
Science
, vol.329
, pp. 689-693
-
-
Tsai, M.C.1
Manor, O.2
Wan, Y.3
Mosammaparast, N.4
Wang, J.K.5
Lan, F.6
Shi, Y.7
Segal, E.8
Chang, H.Y.9
-
213
-
-
78650253763
-
Genome-wide identification of polycomb-associated RNAs by RIP-seq
-
Zhao J, Ohsumi TK, Kung JT, Ogawa Y, Grau DJ, Sarma K, Song JJ, Kingston RE, Borowsky M, Lee JT, (2010) Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell 40: 939-953
-
(2010)
Mol Cell
, vol.40
, pp. 939-953
-
-
Zhao, J.1
Ohsumi, T.K.2
Kung, J.T.3
Ogawa, Y.4
Grau, D.J.5
Sarma, K.6
Song, J.J.7
Kingston, R.E.8
Borowsky, M.9
Lee, J.T.10
-
214
-
-
56549111129
-
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin
-
Nagano T, Mitchell JA, Sanz LA, Pauler FM, Ferguson-Smith AC, Feil R, Fraser P, (2008) The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin. Science 322: 1717-1720
-
(2008)
Science
, vol.322
, pp. 1717-1720
-
-
Nagano, T.1
Mitchell, J.A.2
Sanz, L.A.3
Pauler, F.M.4
Ferguson-Smith, A.C.5
Feil, R.6
Fraser, P.7
-
215
-
-
54049138948
-
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation
-
Pandey RR, Mondal T, Mohammad F, Enroth S, Redrup L, Komorowski J, Nagano T, Mancini-Dinardo D, Kanduri C, (2008) Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation. Mol Cell 32: 232-246
-
(2008)
Mol Cell
, vol.32
, pp. 232-246
-
-
Pandey, R.R.1
Mondal, T.2
Mohammad, F.3
Enroth, S.4
Redrup, L.5
Komorowski, J.6
Nagano, T.7
Mancini-Dinardo, D.8
Kanduri, C.9
-
216
-
-
80052972698
-
The noncoding RNA Mistral activates Hoxa6 and Hoxa7 expression and stem cell differentiation by recruiting MLL1 to chromatin
-
Bertani S, Sauer S, Bolotin E, Sauer F, (2011) The noncoding RNA Mistral activates Hoxa6 and Hoxa7 expression and stem cell differentiation by recruiting MLL1 to chromatin. Mol Cell 43: 1040-1046
-
(2011)
Mol Cell
, vol.43
, pp. 1040-1046
-
-
Bertani, S.1
Sauer, S.2
Bolotin, E.3
Sauer, F.4
-
217
-
-
79953748673
-
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
-
Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, et al (2011) A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 472: 120-124
-
(2011)
Nature
, vol.472
, pp. 120-124
-
-
Wang, K.C.1
Yang, Y.W.2
Liu, B.3
Sanyal, A.4
Corces-Zimmerman, R.5
Chen, Y.6
Lajoie, B.R.7
Protacio, A.8
Flynn, R.A.9
Gupta, R.A.10
-
218
-
-
84874368349
-
Activating RNAs associate with Mediator to enhance chromatin architecture and transcription
-
Lai F, Orom UA, Cesaroni M, Beringer M, Taatjes DJ, Blobel GA, Shiekhattar R, (2013) Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature 494: 497-501
-
(2013)
Nature
, vol.494
, pp. 497-501
-
-
Lai, F.1
Orom, U.A.2
Cesaroni, M.3
Beringer, M.4
Taatjes, D.J.5
Blobel, G.A.6
Shiekhattar, R.7
-
219
-
-
84888057006
-
DNMT1-interacting RNAs block gene-specific DNA methylation
-
Di Ruscio A, Ebralidze AK, Benoukraf T, Amabile G, Goff LA, Terragni J, Figueroa ME, De Figueiredo Pontes LL, Alberich-Jorda M, Zhang P, et al (2013) DNMT1-interacting RNAs block gene-specific DNA methylation. Nature 503: 371-376
-
(2013)
Nature
, vol.503
, pp. 371-376
-
-
Di Ruscio, A.1
Ebralidze, A.K.2
Benoukraf, T.3
Amabile, G.4
Goff, L.A.5
Terragni, J.6
Figueroa, M.E.7
De Figueiredo Pontes, L.L.8
Alberich-Jorda, M.9
Zhang, P.10
-
220
-
-
80052869283
-
LincRNAs act in the circuitry controlling pluripotency and differentiation
-
Guttman M, Donaghey J, Carey BW, Garber M, Grenier JK, Munson G, Young G, Lucas AB, Ach R, Bruhn L, et al (2011) lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature 477: 295-300
-
(2011)
Nature
, vol.477
, pp. 295-300
-
-
Guttman, M.1
Donaghey, J.2
Carey, B.W.3
Garber, M.4
Grenier, J.K.5
Munson, G.6
Young, G.7
Lucas, A.B.8
Ach, R.9
Bruhn, L.10
-
221
-
-
80054719512
-
The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization
-
Duszczyk MM, Wutz A, Rybin V, Sattler M, (2011) The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization. RNA 17: 1973-1982
-
(2011)
RNA
, vol.17
, pp. 1973-1982
-
-
Duszczyk, M.M.1
Wutz, A.2
Rybin, V.3
Sattler, M.4
-
222
-
-
55349109963
-
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome
-
Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT, (2008) Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science 322: 750-756
-
(2008)
Science
, vol.322
, pp. 750-756
-
-
Zhao, J.1
Sun, B.K.2
Erwin, J.A.3
Song, J.J.4
Lee, J.T.5
-
223
-
-
77955418467
-
The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation
-
Royce-Tolland ME, Andersen AA, Koyfman HR, Talbot DJ, Wutz A, Tonks ID, Kay GF, Panning B, (2010) The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation. Nat Struct Mol Biol 17: 948-954
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 948-954
-
-
Royce-Tolland, M.E.1
Andersen, A.A.2
Koyfman, H.R.3
Talbot, D.J.4
Wutz, A.5
Tonks, I.D.6
Kay, G.F.7
Panning, B.8
-
224
-
-
79959948197
-
YY1 tethers Xist RNA to the inactive X nucleation center
-
Jeon Y, Lee JT, (2011) YY1 tethers Xist RNA to the inactive X nucleation center. Cell 146: 119-133
-
(2011)
Cell
, vol.146
, pp. 119-133
-
-
Jeon, Y.1
Lee, J.T.2
-
225
-
-
0033515637
-
A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex
-
Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY, Tsai MJ, O'Malley BW, (1999) A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell 97: 17-27
-
(1999)
Cell
, vol.97
, pp. 17-27
-
-
Lanz, R.B.1
McKenna, N.J.2
Onate, S.A.3
Albrecht, U.4
Wong, J.5
Tsai, S.Y.6
Tsai, M.J.7
O'Malley, B.W.8
-
226
-
-
77951638287
-
Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor
-
Kino T, Hurt DE, Ichijo T, Nader N, Chrousos GP, (2010) Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Sci Signal 3: ra8
-
(2010)
Sci Signal
, vol.3
-
-
Kino, T.1
Hurt, D.E.2
Ichijo, T.3
Nader, N.4
Chrousos, G.P.5
-
227
-
-
46649093597
-
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
-
Wang X, Arai S, Song X, Reichart D, Du K, Pascual G, Tempst P, Rosenfeld MG, Glass CK, Kurokawa R, (2008) Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature 454: 126-130
-
(2008)
Nature
, vol.454
, pp. 126-130
-
-
Wang, X.1
Arai, S.2
Song, X.3
Reichart, D.4
Du, K.5
Pascual, G.6
Tempst, P.7
Rosenfeld, M.G.8
Glass, C.K.9
Kurokawa, R.10
-
228
-
-
0037058999
-
Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA)
-
Lanz RB, Razani B, Goldberg AD, O'Malley BW, (2002) Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA). Proc Natl Acad Sci USA 99: 16081-16086
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16081-16086
-
-
Lanz, R.B.1
Razani, B.2
Goldberg, A.D.3
O'Malley, B.W.4
-
229
-
-
33847234974
-
Pus3p- and Pus1p-dependent pseudouridylation of steroid receptor RNA activator controls a functional switch that regulates nuclear receptor signaling
-
Zhao X, Patton JR, Ghosh SK, Fischel-Ghodsian N, Shen L, Spanjaard RA, (2007) Pus3p- and Pus1p-dependent pseudouridylation of steroid receptor RNA activator controls a functional switch that regulates nuclear receptor signaling. Mol Endocrinol 21: 686-699
-
(2007)
Mol Endocrinol
, vol.21
, pp. 686-699
-
-
Zhao, X.1
Patton, J.R.2
Ghosh, S.K.3
Fischel-Ghodsian, N.4
Shen, L.5
Spanjaard, R.A.6
-
230
-
-
62549117314
-
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles
-
Clemson CM, Hutchinson JN, Sara SA, Ensminger AW, Fox AH, Chess A, Lawrence JB, (2009) An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol Cell 33: 717-726
-
(2009)
Mol Cell
, vol.33
, pp. 717-726
-
-
Clemson, C.M.1
Hutchinson, J.N.2
Sara, S.A.3
Ensminger, A.W.4
Fox, A.H.5
Chess, A.6
Lawrence, J.B.7
-
231
-
-
62449319486
-
MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles
-
Sasaki YT, Ideue T, Sano M, Mituyama T, Hirose T, (2009) MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles. Proc Natl Acad Sci USA 106: 2525-2530
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2525-2530
-
-
Sasaki, Y.T.1
Ideue, T.2
Sano, M.3
Mituyama, T.4
Hirose, T.5
-
232
-
-
61849113891
-
MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles
-
Sunwoo H, Dinger ME, Wilusz JE, Amaral PP, Mattick JS, Spector DL, (2009) MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res 19: 347-359
-
(2009)
Genome Res
, vol.19
, pp. 347-359
-
-
Sunwoo, H.1
Dinger, M.E.2
Wilusz, J.E.3
Amaral, P.P.4
Mattick, J.S.5
Spector, D.L.6
-
233
-
-
84867575580
-
Alternative 3′end processing of long noncoding RNA initiates construction of nuclear paraspeckles
-
Naganuma T, Nakagawa S, Tanigawa A, Sasaki YF, Goshima N, Hirose T, (2012) Alternative 3′end processing of long noncoding RNA initiates construction of nuclear paraspeckles. EMBO J 31: 4020-4034
-
(2012)
EMBO J
, vol.31
, pp. 4020-4034
-
-
Naganuma, T.1
Nakagawa, S.2
Tanigawa, A.3
Sasaki, Y.F.4
Goshima, N.5
Hirose, T.6
-
234
-
-
78649637489
-
Highly ordered spatial organization of the structural long noncoding NEAT1 RNAs within paraspeckle nuclear bodies
-
Souquere S, Beauclair G, Harper F, Fox A, Pierron G, (2010) Highly ordered spatial organization of the structural long noncoding NEAT1 RNAs within paraspeckle nuclear bodies. Mol Biol Cell 21: 4020-4027
-
(2010)
Mol Biol Cell
, vol.21
, pp. 4020-4027
-
-
Souquere, S.1
Beauclair, G.2
Harper, F.3
Fox, A.4
Pierron, G.5
-
235
-
-
84891800602
-
NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies
-
Hirose T, Virnicchi G, Tanigawa A, Naganuma T, Li R, Kimura H, Yokoi T, Nakagawa S, Benard M, Fox AH, et al (2014) NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies. Mol Biol Cell 25: 169-183
-
(2014)
Mol Biol Cell
, vol.25
, pp. 169-183
-
-
Hirose, T.1
Virnicchi, G.2
Tanigawa, A.3
Naganuma, T.4
Li, R.5
Kimura, H.6
Yokoi, T.7
Nakagawa, S.8
Benard, M.9
Fox, A.H.10
-
236
-
-
26844440157
-
Regulating gene expression through RNA nuclear retention
-
Prasanth KV, Prasanth SG, Xuan Z, Hearn S, Freier SM, Bennett CF, Zhang MQ, Spector DL, (2005) Regulating gene expression through RNA nuclear retention. Cell 123: 249-263
-
(2005)
Cell
, vol.123
, pp. 249-263
-
-
Prasanth, K.V.1
Prasanth, S.G.2
Xuan, Z.3
Hearn, S.4
Freier, S.M.5
Bennett, C.F.6
Zhang, M.Q.7
Spector, D.L.8
-
237
-
-
39149127591
-
Transcription of Satellite III non-coding RNAs is a general stress response in human cells
-
Valgardsdottir R, Chiodi I, Giordano M, Rossi A, Bazzini S, Ghigna C, Riva S, Biamonti G, (2008) Transcription of Satellite III non-coding RNAs is a general stress response in human cells. Nucleic Acids Res 36: 423-434
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 423-434
-
-
Valgardsdottir, R.1
Chiodi, I.2
Giordano, M.3
Rossi, A.4
Bazzini, S.5
Ghigna, C.6
Riva, S.7
Biamonti, G.8
-
238
-
-
84863012035
-
Immobilization of proteins in the nucleolus by ribosomal intergenic spacer noncoding RNA
-
Audas TE, Jacob MD, Lee S, (2012) Immobilization of proteins in the nucleolus by ribosomal intergenic spacer noncoding RNA. Mol Cell 45: 147-157
-
(2012)
Mol Cell
, vol.45
, pp. 147-157
-
-
Audas, T.E.1
Jacob, M.D.2
Lee, S.3
-
239
-
-
84884482165
-
Environmental cues induce a long noncoding RNA-dependent remodeling of the nucleolus
-
Jacob MD, Audas TE, Uniacke J, Trinkle-Mulcahy L, Lee S, (2013) Environmental cues induce a long noncoding RNA-dependent remodeling of the nucleolus. Mol Biol Cell 24: 2943-2953
-
(2013)
Mol Biol Cell
, vol.24
, pp. 2943-2953
-
-
Jacob, M.D.1
Audas, T.E.2
Uniacke, J.3
Trinkle-Mulcahy, L.4
Lee, S.5
-
240
-
-
68949212914
-
Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA
-
Chen LL, Carmichael GG, (2009) Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA. Mol Cell 35: 467-478
-
(2009)
Mol Cell
, vol.35
, pp. 467-478
-
-
Chen, L.L.1
Carmichael, G.G.2
-
241
-
-
79955506825
-
Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice
-
Nakagawa S, Naganuma T, Shioi G, Hirose T, (2011) Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice. J Cell Biol 193: 31-39
-
(2011)
J Cell Biol
, vol.193
, pp. 31-39
-
-
Nakagawa, S.1
Naganuma, T.2
Shioi, G.3
Hirose, T.4
-
242
-
-
56349113455
-
3′end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA
-
Wilusz JE, Freier SM, Spector DL, (2008) 3′end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. Cell 135: 919-932
-
(2008)
Cell
, vol.135
, pp. 919-932
-
-
Wilusz, J.E.1
Freier, S.M.2
Spector, D.L.3
-
243
-
-
84869846717
-
Formation of triple-helical structures by the 3′end sequences of MALAT1 and MENbeta noncoding RNAs
-
Brown JA, Valenstein ML, Yario TA, Tycowski KT, Steitz JA, (2012) Formation of triple-helical structures by the 3′end sequences of MALAT1 and MENbeta noncoding RNAs. Proc Natl Acad Sci USA 109: 19202-19207
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 19202-19207
-
-
Brown, J.A.1
Valenstein, M.L.2
Yario, T.A.3
Tycowski, K.T.4
Steitz, J.A.5
-
244
-
-
84868519473
-
A triple helix stabilizes the 3′ends of long noncoding RNAs that lack poly(A) tails
-
Wilusz JE, Jnbaptiste CK, Lu LY, Kuhn CD, Joshua-Tor L, Sharp PA, (2012) A triple helix stabilizes the 3′ends of long noncoding RNAs that lack poly(A) tails. Genes Dev 26: 2392-2407
-
(2012)
Genes Dev
, vol.26
, pp. 2392-2407
-
-
Wilusz, J.E.1
Jnbaptiste, C.K.2
Lu, L.Y.3
Kuhn, C.D.4
Joshua-Tor, L.5
Sharp, P.A.6
-
245
-
-
33845662140
-
Identification of a rapid mammalian deadenylation-dependent decay pathway and its inhibition by a viral RNA element
-
Conrad NK, Mili S, Marshall EL, Shu MD, Steitz JA, (2006) Identification of a rapid mammalian deadenylation-dependent decay pathway and its inhibition by a viral RNA element. Mol Cell 24: 943-953
-
(2006)
Mol Cell
, vol.24
, pp. 943-953
-
-
Conrad, N.K.1
Mili, S.2
Marshall, E.L.3
Shu, M.D.4
Steitz, J.A.5
-
246
-
-
78649422018
-
Poly(A) tail recognition by a viral RNA element through assembly of a triple helix
-
Mitton-Fry RM, DeGregorio SJ, Wang J, Steitz TA, Steitz JA, (2010) Poly(A) tail recognition by a viral RNA element through assembly of a triple helix. Science 330: 1244-1247
-
(2010)
Science
, vol.330
, pp. 1244-1247
-
-
Mitton-Fry, R.M.1
Degregorio, S.J.2
Wang, J.3
Steitz, T.A.4
Steitz, J.A.5
-
247
-
-
84864295521
-
Conservation of a triple-helix-forming RNA stability element in noncoding and genomic RNAs of diverse viruses
-
Tycowski KT, Shu MD, Borah S, Shi M, Steitz JA, (2012) Conservation of a triple-helix-forming RNA stability element in noncoding and genomic RNAs of diverse viruses. Cell Rep 2: 26-32
-
(2012)
Cell Rep
, vol.2
, pp. 26-32
-
-
Tycowski, K.T.1
Shu, M.D.2
Borah, S.3
Shi, M.4
Steitz, J.A.5
-
248
-
-
80052716635
-
Cellular toxicity of expanded RNA repeats: Focus on RNA foci
-
Wojciechowska M, Krzyzosiak WJ, (2011) Cellular toxicity of expanded RNA repeats: focus on RNA foci. Hum Mol Genet 20: 3811-3821
-
(2011)
Hum Mol Genet
, vol.20
, pp. 3811-3821
-
-
Wojciechowska, M.1
Krzyzosiak, W.J.2
-
250
-
-
79951495822
-
LncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′UTRs via Alu elements
-
Gong C, Maquat LE, (2011) lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′UTRs via Alu elements. Nature 470: 284-288
-
(2011)
Nature
, vol.470
, pp. 284-288
-
-
Gong, C.1
Maquat, L.E.2
-
251
-
-
84893725356
-
Staufen1 senses overall transcript secondary structure to regulate translation
-
Ricci EP, Kucukural A, Cenik C, Mercier BC, Singh G, Heyer EE, Ashar-Patel A, Peng L, Moore MJ, (2014) Staufen1 senses overall transcript secondary structure to regulate translation. Nat Struct Mol Biol 21: 26-35
-
(2014)
Nat Struct Mol Biol
, vol.21
, pp. 26-35
-
-
Ricci, E.P.1
Kucukural, A.2
Cenik, C.3
Mercier, B.C.4
Singh, G.5
Heyer, E.E.6
Ashar-Patel, A.7
Peng, L.8
Moore, M.J.9
-
252
-
-
84872135457
-
Control of somatic tissue differentiation by the long non-coding RNA TINCR
-
Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, et al (2013) Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature 493: 231-235
-
(2013)
Nature
, vol.493
, pp. 231-235
-
-
Kretz, M.1
Siprashvili, Z.2
Chu, C.3
Webster, D.E.4
Zehnder, A.5
Qu, K.6
Lee, C.S.7
Flockhart, R.J.8
Groff, A.F.9
Chow, J.10
-
253
-
-
84875372911
-
Natural RNA circles function as efficient microRNA sponges
-
Hansen TB, Jensen TI, Clausen BH, Bramsen JB, Finsen B, Damgaard CK, Kjems J, (2013) Natural RNA circles function as efficient microRNA sponges. Nature 495: 384-388
-
(2013)
Nature
, vol.495
, pp. 384-388
-
-
Hansen, T.B.1
Jensen, T.I.2
Clausen, B.H.3
Bramsen, J.B.4
Finsen, B.5
Damgaard, C.K.6
Kjems, J.7
-
254
-
-
84875369248
-
Circular RNAs are a large class of animal RNAs with regulatory potency
-
Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, et al (2013) Circular RNAs are a large class of animal RNAs with regulatory potency. Nature 495: 333-338
-
(2013)
Nature
, vol.495
, pp. 333-338
-
-
Memczak, S.1
Jens, M.2
Elefsinioti, A.3
Torti, F.4
Krueger, J.5
Rybak, A.6
Maier, L.7
MacKowiak, S.D.8
Gregersen, L.H.9
Munschauer, M.10
-
255
-
-
77956306662
-
Genome-wide measurement of RNA secondary structure in yeast
-
Kertesz M, Wan Y, Mazor E, Rinn JL, Nutter RC, Chang HY, Segal E, (2010) Genome-wide measurement of RNA secondary structure in yeast. Nature 467: 103-107
-
(2010)
Nature
, vol.467
, pp. 103-107
-
-
Kertesz, M.1
Wan, Y.2
Mazor, E.3
Rinn, J.L.4
Nutter, R.C.5
Chang, H.Y.6
Segal, E.7
-
256
-
-
84893351549
-
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo
-
Rouskin S, Zubradt M, Washietl S, Kellis M, Weissman JS, (2013) Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature 505: 701-705
-
(2013)
Nature
, vol.505
, pp. 701-705
-
-
Rouskin, S.1
Zubradt, M.2
Washietl, S.3
Kellis, M.4
Weissman, J.S.5
-
257
-
-
84893427735
-
In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features
-
Ding Y, Tang Y, Kwok CK, Zhang Y, Bevilacqua PC, Assmann SM, (2013) In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features. Nature 505: 696-700
-
(2013)
Nature
, vol.505
, pp. 696-700
-
-
Ding, Y.1
Tang, Y.2
Kwok, C.K.3
Zhang, Y.4
Bevilacqua, P.C.5
Assmann, S.M.6
-
258
-
-
84860779086
-
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
-
Dominissini D, Moshitch-Moshkovitz S, Schwartz S, Salmon-Divon M, Ungar L, Osenberg S, Cesarkas K, Jacob-Hirsch J, Amariglio N, Kupiec M, et al (2012) Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature 485: 201-206
-
(2012)
Nature
, vol.485
, pp. 201-206
-
-
Dominissini, D.1
Moshitch-Moshkovitz, S.2
Schwartz, S.3
Salmon-Divon, M.4
Ungar, L.5
Osenberg, S.6
Cesarkas, K.7
Jacob-Hirsch, J.8
Amariglio, N.9
Kupiec, M.10
-
259
-
-
84862649489
-
Comprehensive analysis of mRNA methylation reveals enrichment in 3′UTRs and near stop codons
-
Meyer KD, Saletore Y, Zumbo P, Elemento O, Mason CE, Jaffrey SR, (2012) Comprehensive analysis of mRNA methylation reveals enrichment in 3′UTRs and near stop codons. Cell 149: 1635-1646
-
(2012)
Cell
, vol.149
, pp. 1635-1646
-
-
Meyer, K.D.1
Saletore, Y.2
Zumbo, P.3
Elemento, O.4
Mason, C.E.5
Jaffrey, S.R.6
-
260
-
-
84860751168
-
Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA
-
Squires JE, Patel HR, Nousch M, Sibbritt T, Humphreys DT, Parker BJ, Suter CM, Preiss T, (2012) Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA. Nucleic Acids Res 40: 5023-5033
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 5023-5033
-
-
Squires, J.E.1
Patel, H.R.2
Nousch, M.3
Sibbritt, T.4
Humphreys, D.T.5
Parker, B.J.6
Suter, C.M.7
Preiss, T.8
-
261
-
-
84877350071
-
Identification of direct targets and modified bases of RNA cytosine methyltransferases
-
Khoddami V, Cairns BR, (2013) Identification of direct targets and modified bases of RNA cytosine methyltransferases. Nat Biotechnol 31: 458-464
-
(2013)
Nat Biotechnol
, vol.31
, pp. 458-464
-
-
Khoddami, V.1
Cairns, B.R.2
-
262
-
-
84880791572
-
NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs
-
Hussain S, Sajini AA, Blanco S, Dietmann S, Lombard P, Sugimoto Y, Paramor M, Gleeson JG, Odom DT, Ule J, et al (2013) NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs. Cell Rep 4: 255-261
-
(2013)
Cell Rep
, vol.4
, pp. 255-261
-
-
Hussain, S.1
Sajini, A.A.2
Blanco, S.3
Dietmann, S.4
Lombard, P.5
Sugimoto, Y.6
Paramor, M.7
Gleeson, J.G.8
Odom, D.T.9
Ule, J.10
-
263
-
-
84895523999
-
A biochemical landscape of A-to-I RNA editing in the human brain transcriptome
-
Sakurai M, Ueda H, Yano T, Okada S, Terajima H, Mitsuyama T, Toyoda A, Fujiyama A, Kawabata H, Suzuki T, (2014) A biochemical landscape of A-to-I RNA editing in the human brain transcriptome. Genome Res 24: 522-534
-
(2014)
Genome Res
, vol.24
, pp. 522-534
-
-
Sakurai, M.1
Ueda, H.2
Yano, T.3
Okada, S.4
Terajima, H.5
Mitsuyama, T.6
Toyoda, A.7
Fujiyama, A.8
Kawabata, H.9
Suzuki, T.10
-
264
-
-
56549105330
-
HITS-CLIP yields genome-wide insights into brain alternative RNA processing
-
Licatalosi DD, Mele A, Fak JJ, Ule J, Kayikci M, Chi SW, Clark TA, Schweitzer AC, Blume JE, Wang X, et al (2008) HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature 456: 464-469
-
(2008)
Nature
, vol.456
, pp. 464-469
-
-
Licatalosi, D.D.1
Mele, A.2
Fak, J.J.3
Ule, J.4
Kayikci, M.5
Chi, S.W.6
Clark, T.A.7
Schweitzer, A.C.8
Blume, J.E.9
Wang, X.10
-
265
-
-
77950920903
-
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
-
Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano MJ, Jungkamp AC, Munschauer M, et al (2010) Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 141: 129-141
-
(2010)
Cell
, vol.141
, pp. 129-141
-
-
Hafner, M.1
Landthaler, M.2
Burger, L.3
Khorshid, M.4
Hausser, J.5
Berninger, P.6
Rothballer, A.7
Ascano, M.J.8
Jungkamp, A.C.9
Munschauer, M.10
-
266
-
-
84861969926
-
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
-
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, et al (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149: 1393-1406
-
(2012)
Cell
, vol.149
, pp. 1393-1406
-
-
Castello, A.1
Fischer, B.2
Eichelbaum, K.3
Horos, R.4
Beckmann, B.M.5
Strein, C.6
Davey, N.E.7
Humphreys, D.T.8
Preiss, T.9
Steinmetz, L.M.10
|