Developmentally regulated piRNA clusters implicate MILI in transposon control

Science

Volumn 316, Issue 5825, 2007, Pages 744-747

  Aravin, Alexei A ^a   Sachidanandam, Ravi ^a   Girard, Angelique ^a   Fejes Toth, Katalin ^a   Hannon, Gregory J ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; RNA;

DNA; FLY; GENOME; PROTEIN; RNA;

ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; DNA METHYLATION; DROSOPHILA; GENE AMPLIFICATION; GENE CONTROL; GENE LOCUS; GENE REPRESSION; MAMMAL; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; REGULATORY RNA SEQUENCE; TRANSPOSON;

3' UNTRANSLATED REGIONS; ANIMALS; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; DNA METHYLATION; GENES, INTRACISTERNAL A-PARTICLE; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MALE; MEIOSIS; MICE; MUTATION; PROTEINS; RETROELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, ANTISENSE; RNA, UNTRANSLATED; SHORT INTERSPERSED NUCLEOTIDE ELEMENTS; SPERMATOCYTES; SPERMATOGENESIS; SUPPRESSION, GENETIC;

INTRACISTERNAL A-PARTICLES; MAMMALIA; MURINAE;

EID: 34248160438     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1142612     Document Type: Article

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21. piRNA sequences are available in the Gene Expression Omnibus (GEO) database (accession # GSE7414). We thank H. Lin (Yale University) for the Mili knockout mouse. AAA. is supported by a Cold Spring Harbor Laboratory Association fellowship. A.G. is a Florence Gould Fellow of the Watson School of Biological Sciences. G.J.H. is an HHMI investigator. This work was supported by grants from NIH and from Katherine W. Davis (G.J.H.).