메뉴 건너뛰기




Volumn 16, Issue 1, 2010, Pages 43-56

Sorting of drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway

Author keywords

Argonaute; microRNA; miRNA; RNA interference; RNAi; siRNA; Small RNA sorting

Indexed keywords

ARGONAUTE 1 PROTEIN; ARGONAUTE 2 PROTEIN; DICER; MICRORNA; SMALL INTERFERING RNA; URIDINE; ARGONAUTE 2 PROTEIN, DROSOPHILA; ARGONAUTE1 PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; INITIATION FACTOR; RNA INDUCED SILENCING COMPLEX;

EID: 75649129754     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.1972910     Document Type: Article
Times cited : (295)

References (80)
  • 1
    • 34447102459 scopus 로고    scopus 로고
    • Molecular Basis for Target RNA Recognition and Cleavage by Human RISC
    • DOI 10.1016/j.cell.2007.04.037, PII S0092867407005831
    • Ameres SL, Martinez J, Schroeder R. 2007. Molecular basis for target RNA recognition and cleavage by human RISC. Cell 130: 101-112. (Pubitemid 47031315)
    • (2007) Cell , vol.130 , Issue.1 , pp. 101-112
    • Ameres, S.L.1    Martinez, J.2    Schroeder, R.3
  • 2
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • DOI 10.1038/35053110
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366. (Pubitemid 32151243)
    • (2001) Nature , vol.409 , Issue.6818 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 3
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • DOI 10.1261/rna.5167604
    • Bohnsack MT, Czaplinski K, Gorlich D. 2004. Exportin 5 is a Ran GTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10: 185-191. (Pubitemid 38129823)
    • (2004) RNA , vol.10 , Issue.2 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 4
    • 23644433363 scopus 로고    scopus 로고
    • TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
    • DOI 10.1038/nature03868
    • Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R. 2005. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436: 740-744. (Pubitemid 41117280)
    • (2005) Nature , vol.436 , Issue.7051 , pp. 740-744
    • Chendrimada, T.P.1    Gregory, R.I.2    Kumaraswamy, E.3    Norman, J.4    Cooch, N.5    Nishikura, K.6    Shiekhattar, R.7
  • 5
    • 44349174824 scopus 로고    scopus 로고
    • Endogenous RNA interference provides a somatic defense against Drosophila transposons
    • Chung WJ, Okamura K, Martin R, Lai EC. 2008. Endogenous RNA interference provides a somatic defense against Drosophila transposons. Curr Biol 18: 795-802.
    • (2008) Curr Biol , vol.18 , pp. 795-802
    • Chung, W.J.1    Okamura, K.2    Martin, R.3    Lai, E.C.4
  • 7
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • DOI 10.1038/nature03049
    • Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ. 2004. Processing of primary microRNAs by the Microprocessor complex. Nature 432: 231-235. (Pubitemid 39545854)
    • (2004) Nature , vol.432 , Issue.7014 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.J.2    Plasterk, R.H.A.3    Ketting, R.F.4    Hannon, G.J.5
  • 8
    • 22744433240 scopus 로고    scopus 로고
    • Normal micro-RNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
    • doi: 10.1016/j.cell.2007.05.056
    • Förstemann K, Tomari Y, Du T, Vagin VV, Denli AM, Bratu DP, Klattenhoff C, Theurkauf WE, Zamore PD. 2005. Normal micro-RNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol 3: e236. doi: 10.1016/j.cell.2007.05.056.
    • (2005) PLoS Biol , vol.3
    • Förstemann, K.1    Tomari, Y.2    Du, T.3    Vagin, V.V.4    Denli, A.M.5    Bratu, D.P.6    Klattenhoff, C.7    Theurkauf, W.E.8    Zamore, P.D.9
  • 9
    • 34447291764 scopus 로고    scopus 로고
    • Drosophila microRNAs Are Sorted into Functionally Distinct Argonaute Complexes after Production by Dicer-1
    • DOI 10.1016/j.cell.2007.05.056, PII S009286740700760X
    • Förstemann K, Horwich MD, Wee L, Tomari Y, Zamore PD. 2007. Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1. Cell 130: 287-297. (Pubitemid 47086327)
    • (2007) Cell , vol.130 , Issue.2 , pp. 287-297
    • Forstemann, K.1    Horwich, M.D.2    Wee, L.3    Tomari, Y.4    Zamore, P.D.5
  • 10
    • 58449134534 scopus 로고    scopus 로고
    • Small silencing RNAs: An expanding universe
    • Ghildiyal M, Zamore PD. 2009. Small silencing RNAs: An expanding universe. Nat Rev Genet 10: 94-108.
    • (2009) Nat Rev Genet , vol.10 , pp. 94-108
    • Ghildiyal, M.1    Zamore, P.D.2
  • 13
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
    • DOI 10.1016/j.molcel.2007.06.017, PII S1097276507004078
    • Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP. 2007. MicroRNA targeting specificity in mammals: Determinants beyond seed pairing. Mol Cell 27: 91-105. (Pubitemid 46991392)
    • (2007) Molecular Cell , vol.27 , Issue.1 , pp. 91-105
    • Grimson, A.1    Farh, K.K.-H.2    Johnston, W.K.3    Garrett-Engele, P.4    Lim, L.P.5    Bartel, D.P.6
  • 14
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G, Mello CC. 2001. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106: 23-34.
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6    Baillie, D.L.7    Fire, A.8    Ruvkun, G.9    Mello, C.C.10
  • 15
    • 27344456287 scopus 로고    scopus 로고
    • MicroRNA target predictions across seven Drosophila species and comparison to mammalian targets
    • doi: 10.1371/journal.pcbi.0010013
    • Grun D, Wang YL, Langenberger D, Gunsalus KC, Rajewsky N. 2005. microRNA target predictions across seven Drosophila species and comparison to mammalian targets. PLoS Comput Biol 1: e13. doi: 10.1371/journal.pcbi.0010013.
    • (2005) PLoS Comput Biol , vol.1
    • Grun, D.1    Wang, Y.L.2    Langenberger, D.3    Gunsalus, K.C.4    Rajewsky, N.5
  • 16
  • 17
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • DOI 10.1038/35005107
    • Hammond SM, Bernstein E, Beach D, Hannon GJ. 2000. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404: 293-296. (Pubitemid 30163547)
    • (2000) Nature , vol.404 , Issue.6775 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 18
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • DOI 10.1101/gad.1262504
    • Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN. 2004. The Drosha - DGCR8 complex in primary microRNA processing. Genes & Dev 18: 3016-3027. (Pubitemid 39658171)
    • (2004) Genes and Development , vol.18 , Issue.24 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.-H.3    Kim, Y.-K.4    Jin, H.5    Kim, V.N.6
  • 19
    • 33744520104 scopus 로고    scopus 로고
    • Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex
    • DOI 10.1016/j.cell.2006.03.043, PII S0092867406005162
    • Han J, Lee Y, Yeom KH, Nam JW, Heo I, Rhee JK, Sohn SY, Cho Y, Zhang BT, Kim VN. 2006. Molecular basis for the recognition of primary microRNAs by the Drosha - DGCR8 complex. Cell 125: 887-901. (Pubitemid 43810154)
    • (2006) Cell , vol.125 , Issue.5 , pp. 887-901
    • Han, J.1    Lee, Y.2    Yeom, K.-H.3    Nam, J.-W.4    Heo, I.5    Rhee, J.-K.6    Sohn, S.Y.7    Cho, Y.8    Zhang, B.-T.9    Kim, V.N.10
  • 20
    • 34447291602 scopus 로고    scopus 로고
    • The Drosophila RNA Methyltransferase, DmHen1, Modifies Germline piRNAs and Single-Stranded siRNAs in RISC
    • DOI 10.1016/j.cub.2007.06.030, PII S0960982207015679
    • Horwich MD, Li C, Matranga C, Vagin V, Farley G, Wang P, Zamore PD. 2007. The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol 17: 1265-1272. (Pubitemid 47043434)
    • (2007) Current Biology , vol.17 , Issue.14 , pp. 1265-1272
    • Horwich, M.D.1    Li, C.2    Matranga, C.3    Vagin, V.4    Farley, G.5    Wang, P.6    Zamore, P.D.7
  • 21
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA
    • DOI 10.1126/science.1062961
    • Hutvágner G, McLachlan J, Pasquinelli AE, Balint É, Tuschl T, Zamore PD. 2001. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293: 834-838. (Pubitemid 32743968)
    • (2001) Science , vol.293 , Issue.5531 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 22
    • 63649105975 scopus 로고    scopus 로고
    • Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression
    • Iwasaki S, Kawamata T, Tomari Y. 2009. Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression. Mol Cell 34: 58-67.
    • (2009) Mol Cell , vol.34 , pp. 58-67
    • Iwasaki, S.1    Kawamata, T.2    Tomari, Y.3
  • 24
    • 33745612464 scopus 로고    scopus 로고
    • Widespread siRNA 'off-target' transcript silencing mediated by seed region sequence complementarity
    • Jackson AL, Burchard J, Schelter J, Chau BN, Cleary M, Lim L, Linsley PS. 2006. Widespread siRNA 'off-target' transcript silencing mediated by seed region sequence complementarity. RNA 12: 1179-1187.
    • (2006) RNA , vol.12 , pp. 1179-1187
    • Jackson, A.L.1    Burchard, J.2    Schelter, J.3    Chau, B.N.4    Cleary, M.5    Lim, L.6    Linsley, P.S.7
  • 25
    • 23044462450 scopus 로고    scopus 로고
    • Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila
    • DOI 10.1101/gad.1334005
    • Jiang F, Ye X, Liu X, Fincher L, McKearin D, Liu Q. 2005. Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila. Genes & Dev 19: 1674-1679. (Pubitemid 41058362)
    • (2005) Genes and Development , vol.19 , Issue.14 , pp. 1674-1679
    • Jiang, F.1    Ye, X.2    Liu, X.3    Fincher, L.4    McKearin, D.5    Liu, Q.6
  • 26
    • 69949127421 scopus 로고    scopus 로고
    • Structural determinants of miRNAs for RISC loading and slicer-independent unwinding
    • Kawamata T, Seitz H, Tomari Y. 2009. Structural determinants of miRNAs for RISC loading and slicer-independent unwinding. Nat Struct Mol Biol 16: 953-960.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 953-960
    • Kawamata, T.1    Seitz, H.2    Tomari, Y.3
  • 27
    • 44349103084 scopus 로고    scopus 로고
    • Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells
    • DOI 10.1038/nature06938, PII NATURE06938
    • Kawamura Y, Saito K, Kin T, Ono Y, Asai K, Sunohara T, Okada TN, Siomi MC, Siomi H. 2008. Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature 453: 793-797. (Pubitemid 351793781)
    • (2008) Nature , vol.453 , Issue.7196 , pp. 793-797
    • Kawamura, Y.1    Saito, K.2    Kin, T.3    Ono, Y.4    Asai, K.5    Sunohara, T.6    Okada, T.N.7    Siomi, M.C.8    Siomi, H.9
  • 28
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • DOI 10.1101/gad.927801
    • Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH. 2001. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes & Dev 15: 2654-2659. (Pubitemid 32988876)
    • (2001) Genes and Development , vol.15 , Issue.20 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.J.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.A.6
  • 29
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • DOI 10.1016/S0092-8674(03)00801-8
    • Khvorova A, Reynolds A, Jayasena SD. 2003. Functional siRNAs and miRNAs exhibit strand bias. Cell 115: 209-216. (Pubitemid 37329584)
    • (2003) Cell , vol.115 , Issue.2 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 30
    • 33845890037 scopus 로고    scopus 로고
    • Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes
    • DOI 10.1261/rna.283207
    • Kim K, Lee YS, Carthew RW. 2006. Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes. RNA 13: 22-29. (Pubitemid 46026177)
    • (2007) RNA , vol.13 , Issue.1 , pp. 22-29
    • Kim, K.1    Lee, Y.S.2    Carthew, R.W.3
  • 32
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • DOI 10.1126/science.1064921
    • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. 2001. Identification of novel genes coding for small expressed RNAs. Science 294: 853-858. (Pubitemid 33032103)
    • (2001) Science , vol.294 , Issue.5543 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 33
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • doi: 10.1186/gb-2009-10-3-r25
    • Langmead B, Trapnell C, Pop M, Salzberg SL. 2009. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10: R25. doi: 10.1186/gb-2009-10-3-r25.
    • (2009) Genome Biol , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 34
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau NC, Lim LP, Weinstein EG, Bartel DP. 2001. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294: 858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 35
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • DOI 10.1126/science.1065329
    • Lee RC, Ambros V. 2001. An extensive class of small RNAs in Caenorhabditis elegans. Science 294: 862-864. (Pubitemid 33032105)
    • (2001) Science , vol.294 , Issue.5543 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 36
    • 0037711556 scopus 로고    scopus 로고
    • Making a better RNAi vector for Drosophila: Use of intron spacers
    • Lee YS, Carthew RW. 2003. Making a better RNAi vector for Drosophila: Use of intron spacers. Methods 30: 322-329.
    • (2003) Methods , vol.30 , pp. 322-329
    • Lee, Y.S.1    Carthew, R.W.2
  • 38
    • 1842816517 scopus 로고    scopus 로고
    • Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
    • DOI 10.1016/S0092-8674(04)00261-2, PII S0092867404002612
    • Lee YS, Nakahara K, Pham JW, Kim K, He Z, Sontheimer EJ, Carthew RW. 2004. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117: 69-81. (Pubitemid 38469899)
    • (2004) Cell , vol.117 , Issue.1 , pp. 69-81
    • Lee, Y.S.1    Nakahara, K.2    Pham, J.W.3    Kim, K.4    He, Z.5    Sontheimer, E.J.6    Carthew, R.W.7
  • 39
    • 32544460452 scopus 로고    scopus 로고
    • The role of PACT in the RNA silencing pathway
    • DOI 10.1038/sj.emboj.7600942, PII 7600942
    • Lee Y, Hur I, Park SY, Kim YK, Suh MR, Kim VN. 2006. The role of PACT in the RNA silencing pathway. EMBO J 25: 522-532. (Pubitemid 43237659)
    • (2006) EMBO Journal , vol.25 , Issue.3 , pp. 522-532
    • Lee, Y.1    Hur, I.2    Park, S.-Y.3    Kim, Y.-K.4    Mi, R.S.5    Kim, V.N.6
  • 40
    • 33645763485 scopus 로고    scopus 로고
    • Cleavage of the siRNA passenger strand during RISC assembly in human cells
    • Leuschner PJ, Ameres SL, Kueng S, Martinez J. 2006. Cleavage of the siRNA passenger strand during RISC assembly in human cells. EMBO Rep 7: 314-320.
    • (2006) EMBO Rep , vol.7 , pp. 314-320
    • Leuschner, P.J.1    Ameres, S.L.2    Kueng, S.3    Martinez, J.4
  • 42
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. 2005. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 44
    • 66449127376 scopus 로고    scopus 로고
    • MiR-199a, a bone morphogenic protein 2-responsive MicroRNA, regulates chondrogenesis via direct targeting to Smad1
    • Lin EA, Kong L, Bai XH, Luan Y, Liu CJ. 2009. miR-199a, a bone morphogenic protein 2-responsive MicroRNA, regulates chondrogenesis via direct targeting to Smad1. J Biol Chem 284: 11326-11335.
    • (2009) J Biol Chem , vol.284 , pp. 11326-11335
    • Lin, E.A.1    Kong, L.2    Bai, X.H.3    Luan, Y.4    Liu, C.J.5
  • 45
    • 0141868916 scopus 로고    scopus 로고
    • R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
    • DOI 10.1126/science.1088710
    • Liu Q, Rand TA, Kalidas S, Du F, Kim HE, Smith DP, Wang X. 2003. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301: 1921-1925. (Pubitemid 37221400)
    • (2003) Science , vol.301 , Issue.5641 , pp. 1921-1925
    • Liu, Q.1    Rand, T.A.2    Kalidas, S.3    Du, F.4    Kim, H.-E.5    Smith, D.P.6    Wang, X.7
  • 47
    • 15844371219 scopus 로고    scopus 로고
    • Structural basis for 5′ -end-specific recognition of guide RNA by the A. fulgidus Piwi protein
    • DOI 10.1038/nature03514
    • Ma JB, Yuan YR, Meister G, Pei Y, Tuschl T, Patel DJ. 2005. Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature 434: 666-670. (Pubitemid 40488561)
    • (2005) Nature , vol.434 , Issue.7033 , pp. 666-670
    • Ma, J.-B.1    Yuan, Y.-R.2    Meister, G.3    Pei, Y.4    Tuschl, T.5    Patel, D.J.6
  • 48
    • 29144431656 scopus 로고    scopus 로고
    • A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
    • DOI 10.1101/gad.1384005
    • Maniataki E, Mourelatos Z. 2005. A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes & Dev 19: 2979-2990. (Pubitemid 41798114)
    • (2005) Genes and Development , vol.19 , Issue.24 , pp. 2979-2990
    • Maniataki, E.1    Mourelatos, Z.2
  • 49
    • 27744590896 scopus 로고    scopus 로고
    • Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
    • DOI 10.1016/j.cell.2005.08.044, PII S0092867405009220
    • Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD. 2005. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123: 607-620. (Pubitemid 41608464)
    • (2005) Cell , vol.123 , Issue.4 , pp. 607-620
    • Matranga, C.1    Tomari, Y.2    Shin, C.3    Bartel, D.P.4    Zamore, P.D.5
  • 51
    • 41349114789 scopus 로고    scopus 로고
    • Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5′ terminal nucleotide
    • Mi S, Cai T,Hu Y, Chen Y, Hodges E, Ni F, Wu L, Li S, Zhou H, Long C, et al. 2008. Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5′ terminal nucleotide. Cell 133: 116-127.
    • (2008) Cell , vol.133 , pp. 116-127
    • Mi, S.1    Cai, T.2    Hu, Y.3    Chen, Y.4    Hodges, E.5    Ni, F.6    Wu, L.7    Li, S.8    Zhou, H.9    Long, C.10
  • 52
    • 28444437427 scopus 로고    scopus 로고
    • Slicer function of Drosophila Argonautes and its involvement in RISC formation
    • DOI 10.1101/gad.1370605
    • Miyoshi K, Tsukumo H, Nagami T, Siomi H, Siomi MC. 2005. Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes & Dev 19: 2837-2848. (Pubitemid 41739969)
    • (2005) Genes and Development , vol.19 , Issue.23 , pp. 2837-2848
    • Miyoshi, K.1    Tsukumo, H.2    Nagami, T.3    Siomi, H.4    Siomi, M.C.5
  • 54
    • 3142729150 scopus 로고    scopus 로고
    • Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
    • DOI 10.1101/gad.1210204
    • Okamura K, Ishizuka A, Siomi H, Siomi MC. 2004. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes & Dev 18: 1655-1666. (Pubitemid 38938183)
    • (2004) Genes and Development , vol.18 , Issue.14 , pp. 1655-1666
    • Okamura, K.1    Ishizuka, A.2    Siomi, H.3    Siomi, M.C.4
  • 55
    • 34447107760 scopus 로고    scopus 로고
    • The Mirtron Pathway Generates microRNA-Class Regulatory RNAs in Drosophila
    • DOI 10.1016/j.cell.2007.06.028, PII S0092867407007957
    • Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC. 2007. The Mirtron Pathway Generates microRNA-Class Regulatory RNAs in Drosophila. Cell 130: 89-100. (Pubitemid 47031325)
    • (2007) Cell , vol.130 , Issue.1 , pp. 89-100
    • Okamura, K.1    Hagen, J.W.2    Duan, H.3    Tyler, D.M.4    Lai, E.C.5
  • 56
    • 44349101881 scopus 로고    scopus 로고
    • Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster
    • DOI 10.1038/nsmb.1438, PII NSMB1438
    • Okamura K, Balla S, Martin R, Liu N, Lai EC. 2008a. Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nat Struct Mol Biol 15: 581-590. (Pubitemid 351799142)
    • (2008) Nature Structural and Molecular Biology , vol.15 , Issue.6 , pp. 581-590
    • Okamura, K.1    Balla, S.2    Martin, R.3    Liu, N.4    Lai, E.C.5
  • 57
    • 44349084754 scopus 로고    scopus 로고
    • The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs
    • DOI 10.1038/nature07015, PII NATURE07015
    • Okamura K, Chung WJ, Ruby JG, Guo H, Bartel DP, Lai EC. 2008b. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature 453: 803-806. (Pubitemid 351793790)
    • (2008) Nature , vol.453 , Issue.7196 , pp. 803-806
    • Okamura, K.1    Chung, W.-J.2    Ruby, J.G.3    Guo, H.4    Bartel, D.P.5    Lai, E.C.6
  • 58
    • 41649089309 scopus 로고    scopus 로고
    • The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution
    • Okamura K, Phillips MD, Tyler DM, Duan H, Chou YT, Lai EC. 2008c. The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution. Nat Struct Mol Biol 15: 354-363.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 354-363
    • Okamura, K.1    Phillips, M.D.2    Tyler, D.M.3    Duan, H.4    Chou, Y.T.5    Lai, E.C.6
  • 59
    • 15844402005 scopus 로고    scopus 로고
    • Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
    • DOI 10.1038/nature03462
    • Parker JS, Roe SM, Barford D. 2005. Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature 434: 663-666. (Pubitemid 40488560)
    • (2005) Nature , vol.434 , Issue.7033 , pp. 663-666
    • Parker, J.S.1    Roe, S.M.2    Barford, D.3
  • 60
    • 58649113420 scopus 로고    scopus 로고
    • Enhancement of the seed-target recognition step in RNA silencing by a PIWI/MID domain protein
    • Parker JS, Parizotto EA, Wang M, Roe SM, Barford D. 2009. Enhancement of the seed-target recognition step in RNA silencing by a PIWI/MID domain protein. Mol Cell 33: 204-214.
    • (2009) Mol Cell , vol.33 , pp. 204-214
    • Parker, J.S.1    Parizotto, E.A.2    Wang, M.3    Roe, S.M.4    Barford, D.5
  • 61
    • 1542297345 scopus 로고    scopus 로고
    • Computational identification of micro-RNA targets
    • Rajewsky N, Socci ND. 2004. Computational identification of micro-RNA targets. Dev Biol 267: 529-535.
    • (2004) Dev Biol , vol.267 , pp. 529-535
    • Rajewsky, N.1    Socci, N.D.2
  • 63
    • 27744506761 scopus 로고    scopus 로고
    • Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
    • DOI 10.1016/j.cell.2005.10.020, PII S0092867405011074
    • Rand TA, Petersen S, Du F, Wang X. 2005. Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell 123: 621-629. (Pubitemid 41608465)
    • (2005) Cell , vol.123 , Issue.4 , pp. 621-629
    • Rand, T.A.1    Petersen, S.2    Du, F.3    Wang, X.4
  • 65
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • Ruby JG, Jan CH, Bartel DP. 2007a. Intronic microRNA precursors that bypass Drosha processing. Nature 448: 83-86.
    • (2007) Nature , vol.448 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 66
    • 38149071979 scopus 로고    scopus 로고
    • Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    • DOI 10.1101/gr.6597907
    • Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC. 2007b. Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Res 17: 1850-1864. (Pubitemid 351360008)
    • (2007) Genome Research , vol.17 , Issue.12 , pp. 1850-1864
    • Ruby, J.G.1    Stark, A.2    Johnston, W.K.3    Kellis, M.4    Bartel, D.P.5    Lai, E.C.6
  • 67
    • 22744454230 scopus 로고    scopus 로고
    • Processing of premicroRNAs by the Dicer-1-Loquacious complex in Drosophila cells
    • doi: 10.1371/journal.pbio.0030235
    • Saito K, Ishizuka A, Siomi H, Siomi MC. 2005. Processing of premicroRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol 3: e235. doi: 10.1371/journal.pbio.0030235.
    • (2005) PLoS Biol , vol.3
    • Saito, K.1    Ishizuka, A.2    Siomi, H.3    Siomi, M.C.4
  • 68
    • 34347378274 scopus 로고    scopus 로고
    • Pimet, the Drosophila homolog of HEN1, mediates 2′-O-methylation of Piwi-interacting RNAs at their 3′ ends
    • DOI 10.1101/gad.1563607
    • Saito K, Sakaguchi Y, Suzuki T, Suzuki T, Siomi H, Siomi MC. 2007. Pimet, the Drosophila homolog of HEN1, mediates 2′-O-methylation of Piwi- interacting RNAs at their 3′ ends. Genes & Dev 21: 1603-1608. (Pubitemid 47026364)
    • (2007) Genes and Development , vol.21 , Issue.13 , pp. 1603-1608
    • Saito, K.1    Sakaguchi, Y.2    Suzuki, T.3    Suzuki, T.4    Siomi, H.5    Siomi, M.C.6
  • 69
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • DOI 10.1016/S0092-8674(03)00759-1
    • Schwarz DS, Hutvágner G, Du T, Xu Z, Aronin N, Zamore PD. 2003. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115: 199-208. (Pubitemid 37329583)
    • (2003) Cell , vol.115 , Issue.2 , pp. 199-208
    • Schwarz, D.S.1    Hutvagner, G.2    Du, T.3    Xu, Z.4    Aronin, N.5    Zamore, P.D.6
  • 70
    • 38349081145 scopus 로고    scopus 로고
    • Argonaute loading improves the 59 precision of both microRNAs and their miRNA* strands in flies
    • Seitz H, Ghildiyal M, Zamore PD. 2008. Argonaute loading improves the 59 precision of both microRNAs and their miRNA* strands in flies. Curr Biol 18: 147-151.
    • (2008) Curr Biol , vol.18 , pp. 147-151
    • Seitz, H.1    Ghildiyal, M.2    Zamore, P.D.3
  • 74
    • 34447642555 scopus 로고    scopus 로고
    • Sorting of Drosophila Small Silencing RNAs
    • DOI 10.1016/j.cell.2007.05.057, PII S0092867407007611
    • Tomari Y, Du T, Zamore PD. 2007. Sorting of Drosophila small silencing RNAs. Cell 130: 299-308. (Pubitemid 47086328)
    • (2007) Cell , vol.130 , Issue.2 , pp. 299-308
    • Tomari, Y.1    Du, T.2    Zamore, P.D.3
  • 75
    • 0033572660 scopus 로고    scopus 로고
    • Targeted mRNA degradation by double-stranded RNA in vitro
    • DOI 10.1101/gad.13.24.3191
    • Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. 1999. Targeted mRNA degradation by double-stranded RNA in vitro. Genes & Dev 13: 3191-3197. (Pubitemid 30030441)
    • (1999) Genes and Development , vol.13 , Issue.24 , pp. 3191-3197
    • Tuschl, T.1    Zamore, P.D.2    Lehmann, R.3    Bartel, D.P.4    Sharp, P.A.5
  • 76
    • 38149022486 scopus 로고    scopus 로고
    • Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci
    • Tyler DM, Okamura K, Chung WJ, Hagen JW, Berezikov E, Hannon GJ, Lai EC. 2008. Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci. Genes & Dev 22: 26-36.
    • (2008) Genes & Dev , vol.22 , pp. 26-36
    • Tyler, D.M.1    Okamura, K.2    Chung, W.J.3    Hagen, J.W.4    Berezikov, E.5    Hannon, G.J.6    Lai, E.C.7
  • 77
    • 57749206034 scopus 로고    scopus 로고
    • Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex
    • Wang Y, Juranek S, Li H, Sheng G, Tuschl T, Patel DJ. 2008. Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature 456: 921-926.
    • (2008) Nature , vol.456 , pp. 921-926
    • Wang, Y.1    Juranek, S.2    Li, H.3    Sheng, G.4    Tuschl, T.5    Patel, D.J.6
  • 78
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • DOI 10.1101/gad.1158803
    • Yi R, Qin Y, Macara IG, Cullen BR. 2003. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes & Dev 17: 3011-3016. (Pubitemid 38040764)
    • (2003) Genes and Development , vol.17 , Issue.24 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 79
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore PD, Tuschl T, Sharp PA, Bartel DP. 2000. RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101: 25-33.
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 80
    • 12544255565 scopus 로고    scopus 로고
    • Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
    • Zeng Y, Yi R, Cullen BR. 2005. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J 24: 38-48.
    • (2005) EMBO J , vol.24 , pp. 38-48
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.