piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells

Development

Volumn 127, Issue 3, 2000, Pages 503-514

  Cox, Daniel N ^a   Chao, Anna ^a   Lin, Haifan ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Asymmetric division; Cell fate; Drosophila melanogaster; Germline; piwi; Stem cell

Indexed keywords

NUCLEAR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIVISION; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA; FEMALE; GENE FUNCTION; GERM CELL; MALE; NONHUMAN; PRIORITY JOURNAL; SOMATIC CELL; STEM CELL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL DIVISION; CELL NUCLEUS; DROSOPHILA; FEMALE; GENES, MYC; INSECT PROTEINS; MALE; OPEN READING FRAMES; OVARY; OVUM; PROTEINS; RECOMBINANT FUSION PROTEINS; STEM CELLS;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0033966406     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Barker, D. D., Wang, C., Moore, J., Dickson, L. K. and Lehmann, R. (1992). pumilio is essential for function but not for distribution of the Drosophila abdominal determinant nanos. Genes Dev. 6, 2312-2326.
2. Benfey, P. N. (1999). Stem cells: A tale of two kingdoms. Curr. Biol. 9, 171-172.
3. Bohmert, K., Camus, I., Bellini, C., Bouchez, D., Caboche, M. and Benning, C. (1998). AGO1 defines a novel locus of Arabidopsis controlling leaf development. EMBO J. 17, 170-180.
4. Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
5. Brown, E. H. and King, R. C. (1962). Oogonial and spermatogonial differentiation within a mosaic gonad of Drosophila melanogaster. Growth 26, 53-70.
6. Brown, E. H. and King, R. C. (1964). Studies on the events resulting in the formation of an egg chamber in Drosophila melanogaster. Growth 28, 41-81.
7. Byers, T. J., Dubreuil, R. R., Branton, D., Kiehart, D. P. and Goldstein, L. S. B. (1987). Drosophila spectrin II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins. J. Cell Biol. 105, 2103-2110.
8. Cox, D. N., Chao, A., Baker, J., Chang, L., Qiao, D. and Lin, H. (1998). A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev. 12, 3715-3727.
9. Deng, W. and Lin, H. (1997). Spectrosomes and fusomes are essential for anchoring mitotic spindles during asymmetric germ cell divisions and for the microtubule-based RNA transport during oocyte specification in Drosophila. Dev. Biol. 189, 79-94.
10. de Cuevas, M. and Spradling, A. C. (1998). Morphogenesis of the Drosophila fusome and its implications for oocyte specification. Development 125, 2781-2789.
11. Evan, G. I., Lewis, G. K., Ramsay, G. and Bishop, J. M. (1985). Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5, 3610-3616.
12. Forbes, A. and Lehmann, R. (1998). Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells. Development 125, 679-690.
13. Fuller, M. (1993). Spermatogenesis. In Drosophila Development. (ed. M. Bate and A. Martinez Arias), pp. 71-148. Cold Spring Harbor, NY: Cold Spring Harbor Press.
14. Gonczy, P. and DiNardo, S. (1996). The germ line regulates somatic cyst cell proliferation and fate during Drosophila spermatogenesis. Development 122, 2437-2447.
15. Hay, B., Jan, L. Y. and Jan, Y. N. (1990). Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity. Development 109, 425-433.
16. King, R. C. (1970). Ovarian development in Drosophila melanogaster. New York, NY: Academic Press.
17. King, F. J. and Lin, H. (1999). Somatic signaling mediated by fs(1)Yb is essential for germline stem cell maintenance during Drosophila oogenesis. Development 126, 1833-1844.
18. Knoblich, J. A. (1997). Mechanisms of asymmetric cell division during animal development. Curr. Opin. Cell Biol. 9, 833-841.
19. Lecuit, T. and Cohen, S. M. (1997). Proximal-distal axis formation in the Drosophila leg. Nature 388, 139-145.
20. Lin, H. (1997). The tao of stem cells in the germline. Annu. Rev. Genet. 31, 455-491.
21. Lin, H. (1998). The self-renewing mechanism of stem cells in the germline. Curr. Opin. Cell Biol. 10, 687-693.
22. Lin, H. and Schagat, T. (1997). Neuroblasts: a model for asymmetric division of stem cells. Trends Genet. 13, 33-39.
23. Lin, H. and Spradling, A. C. (1993). Germline stem cell division and egg chamber development in transplanted Drosophila germaria. Dev. Biol. 159, 140-152.
24. Lin, H. and Spradling, A. C. (1995). Fusome asymmetry and oocyte determination. Dev. Genet. 16, 6-12.
25. Lin, H. and Spradling, A. C. (1997). A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary. Development 124, 2463-2476.
26. Lin, H., Yue, L. and Spradling, A. C. (1994). The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation. Development 120, 947-956.
27. Lindsley, D.L. and Zimm, G. G. (1992). The genome of Drosophila melanogaster. New York, NY: Academic Press Inc.
28. Margolis, J. and Spradling, A. C. (1995). Identification and behavior of epithelial stem cells in the Drosophila ovary. Development 121, 3797-3807.
29. McKearin, D. and Ohlstein, B. (1995). A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells. Development 121, 2937-2947.
30. McKearin, D. and Spradling, A. C. (1990). bag-of-marbles: a Drosophila gene required to initiate both male and female gametogenesis. Genes Dev. 4, 2242-2251.
31. Morrison, S. J., Shah, N. M. and Anderson, D. J. (1997). Regulatory mechanisms in stem cell biology. Cell 88, 287-298.
32. Moussian, B., Schoof, H., Haecker, A., Jurgens, G. and Laux, T. (1998). Role of the ZWILLE gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis. EMBO J. 17, 1799-1809.
33. Murata, Y. and Wharton, R. P. (1995). Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in Drosophila embryos. Cell 80, 747-756.
34. Parisi, M. J. and Lin, H. (1998). The role of the hedgehog/patched signaling pathway in epithelial stem cell proliferation: from fly to human. Cell Res. 8, 15-21.
35. Parisi, M. J. and Lin, H. (1999). The Drosophila pumilio gene encodes two functional protein isoforms that play multiple roles in germline development, gonadogenesis, oogenesis and embryogenesis. Genetics 153, 235-250.
36. Pirrotta, V. (1988). Vectors for P-element transformation in Drosophila. In Vectors. A survey of Molecular Cloning Vectors and Their Uses (ed. R. L. Rodriguez and D. T. Denhardt), pp. 437-456. London, UK: Butterworths.
37. Potten, C. S. (1997). Stem Cells. London, UK: Academic Press.
38. Robertson, H. M., Preston, C. R., Phillis, R. W., Johnson-Schlitz, D. M., Benz, W. K. and Engles, W. R. (1988). A stable source of P element transposase in Drosophila melanogaster. Genetics 118, 461-470.
39. Rorth, P. (1996). A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. Proc. Natl. Acad. Sci. USA 93, 12418-12422.
40. Rorth, P., Szabo, K., Bailey, A., Laverty, T., Rehm, J., Rubin, G. M., Weigmann, K., Milan, M., Benes, V., Ansorge, W. and Cohen, S. M. (1998). Systematic gain-of-function genetics in Drosophila. Development 125, 1049-1057.
41. Rorth, P. (1998). Gal4 in the Drosophila female germline. Mech. Dev. 78, 113-118.
42. Schupbach, T., Wieschaus, E. and Rothiger, R. (1978). A study of the female germ line in mosaics of Drosophila. Willhelm Roux Arch. Dev Biol. 184, 41-56.
43. Spradling, A. (1993). Developmental Genetics of Oogenesis. In Drosophila Development (eds. M. Bate and A. Martinez Arias), pp. 1-70. Cold Spring Harbor, NY: Cold Spring Harbor Press.
44. Spradling, A. C. and Rubin, G. M. (1982). Transposition of cloned P elements into Drosophila germline chromosomes. Science 218, 341-347.
45. Wieschaus, E. and Szabad, J. (1979). The development and function of the female germline in Drosophila melanogaster, a cell lineage study. Dev. Biol. 68, 29-46.
46. Xie, T. and Spradling, A. C. (1998). decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell 94, 251-260.
47. Xu, T. and Rubin, G. M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
48. Zaccai, M. and Lipshitz, H. D. (1996). Differential distributions of two adducin-like protein isoforms in the Drosophila ovary and early embryo. Zygote 4, 159-166.