A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila

Science

Volumn 315, Issue 5818, 2007, Pages 1587-1590

  Gunawardane, Lalith S ^a   Saito, Kuniaki ^a   Nishida, Kazumichi M ^a   Miyoshi, Keita ^a   Kawamura, Yoshinori ^a   Nagami, Tomoko ^a   Siomi, Haruhiko ^a   Siomi, Mikiko C ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ANTISENSE OLIGONUCLEOTIDE; AUBERGINE PROTEIN; GENE PRODUCT; NUCLEOTIDE; PROTEIN PIWI; PROTEIN SLICER; REPEAT ASSOCIATION SMALL INTERFERING RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; URACIL;

FLY; GENETIC ANALYSIS; GENETIC ENGINEERING; PROTEIN; RNA;

ARTICLE; DROSOPHILA; GERM LINE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RETROPOSON; RNA SEQUENCE; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE LIBRARY; MALE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; OVARY; PEPTIDE INITIATION FACTORS; PROTEINS; RECOMBINANT FUSION PROTEINS; RETROELEMENTS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TESTIS;

SOLANUM MELONGENA;

EID: 33947390781     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1140494     Document Type: Article

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21. We thank T. Suzuki and V. V. Vagin for technical advice; T. Mori, M. Shinomiya, and A. Kinouchi for assistance with fly husbandry and dissection; and members of the Siomi laboratory for discussions and comments on the manuscript. Supported by the Ministry of Education, Culture, Sports, Science, and Technology of Japan (M.C.S., H.S.) and its 21st Century Centers of Excellence Program (L.S.G., K.S.), the Japan Society for the Promotion of Science (JSPS) (M.C.S. and H.S.), a JSPS research fellowship (K.M.), and the New Energy and Industrial Technology Development Organization (M.C.S).