-
1
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel, D.P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009).
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
2
-
-
78751477191
-
Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
-
Huntzinger, E. & Izaurralde, E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat. Rev. Genet. 12, 99-110 (2011).
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 99-110
-
-
Huntzinger, E.1
Izaurralde, E.2
-
3
-
-
77953629046
-
Regulation of mRNA translation and stability by microRNAs
-
Fabian, M.R., Sonenberg, N. & Filipowicz, W. Regulation of mRNA translation and stability by microRNAs. Annu. Rev. Biochem. 79, 351-379 (2010).
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 351-379
-
-
Fabian, M.R.1
Sonenberg, N.2
Filipowicz, W.3
-
4
-
-
79551627496
-
A parsimonious model for gene regulation by miRNAs
-
Djuranovic, S., Nahvi, A. & Green, R. A parsimonious model for gene regulation by miRNAs. Science 331, 550-553 (2011).
-
(2011)
Science
, vol.331
, pp. 550-553
-
-
Djuranovic, S.1
Nahvi, A.2
Green, R.3
-
5
-
-
65249161794
-
Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila
-
Chekulaeva, M., Filipowicz, W. & Parker, R. Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila. RNA 15, 794-803 (2009).
-
(2009)
RNA
, vol.15
, pp. 794-803
-
-
Chekulaeva, M.1
Filipowicz, W.2
Parker, R.3
-
6
-
-
66049131897
-
The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing
-
Eulalio, A. et al. The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing. Nucleic Acids Res. 37, 2974-2983 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 2974-2983
-
-
Eulalio, A.1
-
7
-
-
71949121493
-
The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of miRNA targets and is required for target release
-
Zekri, L., Huntzinger, E., Heimstadt, S. & Izaurralde, E. The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of miRNA targets and is required for target release. Mol. Cell. Biol. 23, 6220-6231 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.23
, pp. 6220-6231
-
-
Zekri, L.1
Huntzinger, E.2
Heimstadt, S.3
Izaurralde, E.4
-
8
-
-
78650258635
-
Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing
-
Huntzinger, E., Braun, J.E., Heimstadt, S., Zekri, L. & Izaurralde, E. Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing. EMBO J. 29, 4146-4160 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 4146-4160
-
-
Huntzinger, E.1
Braun, J.E.2
Heimstadt, S.3
Zekri, L.4
Izaurralde, E.5
-
9
-
-
65249083468
-
Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression
-
Zipprich, J.T., Bhattacharyya, S., Mathys, H. & Filipowicz, W. Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression. RNA 15, 781-793 (2009).
-
(2009)
RNA
, vol.15
, pp. 781-793
-
-
Zipprich, J.T.1
Bhattacharyya, S.2
Mathys, H.3
Filipowicz, W.4
-
10
-
-
66449123316
-
The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins
-
Lazzaretti, D., Tournier, I. & Izaurralde, E. The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins. RNA 15, 1059-1066 (2009).
-
(2009)
RNA
, vol.15
, pp. 1059-1066
-
-
Lazzaretti, D.1
Tournier, I.2
Izaurralde, E.3
-
11
-
-
67651222298
-
Functional dissection of the human TNRC6 (GW182-related) family of proteins
-
Baillat, D. & Shiekhattar, R. Functional dissection of the human TNRC6 (GW182-related) family of proteins. Mol. Cell. Biol. 29, 4144-4155 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4144-4155
-
-
Baillat, D.1
Shiekhattar, R.2
-
12
-
-
70349177026
-
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABPdependent deadenylation
-
Fabian, M.R. et al. Mammalian miRNA RISC recruits CAF1 and PABP to affect PABPdependent deadenylation. Mol. Cell 35, 868-880 (2009).
-
(2009)
Mol. Cell
, vol.35
, pp. 868-880
-
-
Fabian, M.R.1
-
13
-
-
76349104822
-
Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation
-
Jinek, M., Fabian, M.R., Coyle, S.M., Sonenberg, N. & Doudna, J.A. Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation. Nat. Struct. Mol. Biol. 17, 238-240 (2010).
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 238-240
-
-
Jinek, M.1
Fabian, M.R.2
Coyle, S.M.3
Sonenberg, N.4
Doudna, J.A.5
-
14
-
-
33746055678
-
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
-
DOI 10.1101/gad.1424106
-
Behm-Ansmant, I. et al. mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev. 20, 1885-1898 (2006). (Pubitemid 44079326)
-
(2006)
Genes and Development
, vol.20
, Issue.14
, pp. 1885-1898
-
-
Behm-Ansmant, I.1
Rehwinkel, J.2
Doerks, T.3
Stark, A.4
Bork, P.5
Izaurralde, E.6
-
15
-
-
70350780068
-
Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps
-
Chen, C.Y., Zheng, D., Xia, Z. & Shyu, A.B. Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps. Nat. Struct. Mol. Biol. 16, 1160-1166 (2009).
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1160-1166
-
-
Chen, C.Y.1
Zheng, D.2
Xia, Z.3
Shyu, A.B.4
-
16
-
-
77749334621
-
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
-
Piao, X., Zhang, X., Wu, L. & Belasco, J.G. CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells. Mol. Cell. Biol. 30, 1486-1494 (2010).
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1486-1494
-
-
Piao, X.1
Zhang, X.2
Wu, L.3
Belasco, J.G.4
-
17
-
-
78049393669
-
The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression
-
Chekulaeva, M., Parker, R. & Filipowicz, W. The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression. Nucleic Acids Res. 38, 6673-6683 (2010).
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 6673-6683
-
-
Chekulaeva, M.1
Parker, R.2
Filipowicz, W.3
-
18
-
-
79954610487
-
Divergent GW182 functional domains in the regulation of translational silencing
-
Yao, B. et al. Divergent GW182 functional domains in the regulation of translational silencing. Nucleic Acids Res. 39, 2534-2547 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 2534-2547
-
-
Yao, B.1
-
19
-
-
36049016095
-
Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation
-
DOI 10.1128/MCB.01254-07
-
Ezzeddine, N. et al. Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation. Mol. Cell. Biol. 27, 7791-7801 (2007). (Pubitemid 350086413)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.22
, pp. 7791-7801
-
-
Ezzeddine, N.1
Chang, T.-C.2
Zhu, W.3
Yamashita, A.4
Chen, C.-Y.A.5
Zhong, Z.6
Yamashita, Y.7
Zheng, D.8
Shyu, A.-B.9
-
20
-
-
34548359334
-
Poly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding protein
-
DOI 10.1074/jbc.M701256200
-
Siddiqui, N. et al. Poly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding protein. J. Biol. Chem. 282, 25067-25075 (2007). (Pubitemid 47347518)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.34
, pp. 25067-25075
-
-
Siddiqui, N.1
Mangus, D.A.2
Chang, T.-C.3
Palermino, J.-M.4
Shyu, A.-B.5
Gehring, K.6
-
21
-
-
77951631601
-
Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase
-
Mittag, T. et al. Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase. Structure 18, 494-506 (2010).
-
(2010)
Structure
, vol.18
, pp. 494-506
-
-
Mittag, T.1
-
22
-
-
66449124170
-
A C-terminal silencing domain in GW182 is essential for miRNA function
-
Eulalio, A., Helms, S., Fritzsch, C., Fauser, M. & Izaurralde, E. A C-terminal silencing domain in GW182 is essential for miRNA function. RNA 15, 1067-1077 (2009).
-
(2009)
RNA
, vol.15
, pp. 1067-1077
-
-
Eulalio, A.1
Helms, S.2
Fritzsch, C.3
Fauser, M.4
Izaurralde, E.5
-
23
-
-
35748932681
-
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells
-
DOI 10.1038/sj.embor.7401088, PII 7401088
-
Höck, J. et al. Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO Rep. 8, 1052-1060 (2007). (Pubitemid 350042341)
-
(2007)
EMBO Reports
, vol.8
, Issue.11
, pp. 1052-1060
-
-
Hock, J.1
Weinmann, L.2
Ender, C.3
Rudel, S.4
Kremmer, E.5
Raabe, M.6
Urlaub, H.7
Meister, G.8
-
24
-
-
33947431322
-
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
-
DOI 10.1126/science.1137999
-
Mayr, C., Hemann, M.T. & Bartel, D.P. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315, 1576-1579 (2007). (Pubitemid 46449474)
-
(2007)
Science
, vol.315
, Issue.5818
, pp. 1576-1579
-
-
Mayr, C.1
Hemann, M.T.2
Bartel, D.P.3
-
25
-
-
58149103297
-
Deadenylation is a widespread effect of miRNA regulation
-
Eulalio, A. et al. Deadenylation is a widespread effect of miRNA regulation. RNA 15, 21-32 (2009).
-
(2009)
RNA
, vol.15
, pp. 21-32
-
-
Eulalio, A.1
-
26
-
-
4143055666
-
The Eukaryotic Ccr4-Not Complex: A Regulatory Platform Integrating mRNA Metabolism with Cellular Signaling Pathways?
-
DOI 10.1016/S0079-6603(04)77008-7, PII S0079660304770087
-
Collart, M.A. & Timmers, H.T. The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways? Prog. Nucleic Acid Res. Mol. Biol. 77, 289-322 (2004). (Pubitemid 39752475)
-
(2004)
Progress in Nucleic Acid Research and Molecular Biology
, vol.77
, pp. 289-322
-
-
Collart, M.A.1
Timmers, H.Th.M.2
-
27
-
-
80555150587
-
MiRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT
-
doi:10.1038/nsmb.2149 (published online 7 Oct 2011)
-
Fabian, M.R. et al. miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. Nat. Struct. Mol. Biol. doi:10.1038/nsmb.2149 (published online 7 Oct 2011).
-
Nat. Struct. Mol. Biol.
-
-
Fabian, M.R.1
-
28
-
-
31344448006
-
65 binding sites within SF3b155: Thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors
-
DOI 10.1016/j.jmb.2005.11.067, PII S0022283605014853
-
Thickman, K.R., Swenson, M.C., Kabogo, J.M., Gryczynski, Z. & Kielkopf, C.L. Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors. J. Mol. Biol. 356, 664-683 (2006). (Pubitemid 43139328)
-
(2006)
Journal of Molecular Biology
, vol.356
, Issue.3
, pp. 664-683
-
-
Thickman, K.R.1
Swenson, M.C.2
Kabogo, J.M.3
Gryczynski, Z.4
Kielkopf, C.L.5
-
29
-
-
77956503398
-
Translational repression by deadenylases
-
Cooke, A., Prigge, A. & Wickens, M. Translational repression by deadenylases. J. Biol. Chem. 285, 28506-28513 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 28506-28513
-
-
Cooke, A.1
Prigge, A.2
Wickens, M.3
-
30
-
-
0035674477
-
The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes
-
DOI 10.1017/S135583820101994X
-
Coller, J.M., Tucker, M., Sheth, U., Valencia-Sanchez, M.A. & Parker, R. The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA 7, 1717-1727 (2001). (Pubitemid 34042287)
-
(2001)
RNA
, vol.7
, Issue.12
, pp. 1717-1727
-
-
Coller, J.M.1
Tucker, M.2
Sheth, U.3
Valencia-Sanchez, M.A.4
Parker, R.5
-
31
-
-
77953629665
-
Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation
-
Temme, C. et al. Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation. RNA 16, 1356-1370 (2010).
-
(2010)
RNA
, vol.16
, pp. 1356-1370
-
-
Temme, C.1
-
32
-
-
33745894330
-
Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54
-
Chu, C.Y. & Rana, T.M. Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol. 4, e210 (2006).
-
(2006)
PLoS Biol.
, vol.4
-
-
Chu, C.Y.1
Rana, T.M.2
-
33
-
-
33845445765
-
Staufen- and FMRP-Containing Neuronal RNPs Are Structurally and Functionally Related to Somatic P Bodies
-
DOI 10.1016/j.neuron.2006.10.028, PII S0896627306008270
-
Barbee, S.A. et al. Staufen-and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies. Neuron 52, 997-1009 (2006). (Pubitemid 44909400)
-
(2006)
Neuron
, vol.52
, Issue.6
, pp. 997-1009
-
-
Barbee, S.A.1
Estes, P.S.2
Cziko, A.-M.3
Hillebrand, J.4
Luedeman, R.A.5
Coller, J.M.6
Johnson, N.7
Howlett, I.C.8
Geng, C.9
Ueda, R.10
Brand, A.H.11
Newbury, S.F.12
Wilhelm, J.E.13
Levine, R.B.14
Nakamura, A.15
Parker, R.16
Ramaswami, M.17
-
34
-
-
35348962568
-
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing
-
DOI 10.1101/gad.443107
-
Eulalio, A. et al. Target-specific requirements for enhancers of decapping in miRNAmediated gene silencing. Genes Dev. 21, 2558-2570 (2007). (Pubitemid 47607667)
-
(2007)
Genes and Development
, vol.21
, Issue.20
, pp. 2558-2570
-
-
Eulalio, A.1
Rehwinkel, J.2
Stricker, M.3
Huntzinger, E.4
Yang, S.-F.5
Doerks, T.6
Dorner, S.7
Bork, P.8
Boutros, M.9
Izaurralde, E.10
-
35
-
-
33750490399
-
Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex
-
DOI 10.1038/sj.emboj.7601377, PII 7601377
-
Glavan, F., Behm-Ansmant, I., Izaurralde, E. & Conti, E. Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. EMBO J. 25, 5117-5125 (2006). (Pubitemid 44658529)
-
(2006)
EMBO Journal
, vol.25
, Issue.21
, pp. 5117-5125
-
-
Glavan, F.1
Behm-Ansmant, I.2
Izaurralde, E.3
Conti, E.4
-
36
-
-
65549160545
-
Inducible expression of coding and inhibitory RNAs from retargetable genomic loci
-
Weidenfeld, I. et al. Inducible expression of coding and inhibitory RNAs from retargetable genomic loci. Nucleic Acids Res. 37, e50 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Weidenfeld, I.1
-
37
-
-
35748932681
-
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells
-
DOI 10.1038/sj.embor.7401088, PII 7401088
-
Höck, J. et al. Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO Rep. 8, 1052-1060 (2007). (Pubitemid 350042341)
-
(2007)
EMBO Reports
, vol.8
, Issue.11
, pp. 1052-1060
-
-
Hock, J.1
Weinmann, L.2
Ender, C.3
Rudel, S.4
Kremmer, E.5
Raabe, M.6
Urlaub, H.7
Meister, G.8
-
38
-
-
33947431322
-
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
-
DOI 10.1126/science.1137999
-
Mayr, C., Hemann, M.T. & Bartel, D.P. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315, 1576-1579 (2007). (Pubitemid 46449474)
-
(2007)
Science
, vol.315
, Issue.5818
, pp. 1576-1579
-
-
Mayr, C.1
Hemann, M.T.2
Bartel, D.P.3
-
39
-
-
65249161794
-
Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila
-
Chekulaeva, M., Filipowicz, W. & Parker, R. Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila. RNA 15, 794-803 (2009).
-
(2009)
RNA
, vol.15
, pp. 794-803
-
-
Chekulaeva, M.1
Filipowicz, W.2
Parker, R.3
-
40
-
-
70349177026
-
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABPdependent deadenylation
-
Fabian, M.R. et al. Mammalian miRNA RISC recruits CAF1 and PABP to affect PABPdependent deadenylation. Mol. Cell 35, 868-880 (2009).
-
(2009)
Mol. Cell
, vol.35
, pp. 868-880
-
-
Fabian, M.R.1
|