-
1
-
-
44049102683
-
Single particle image reconstruction of the human recombinant Kv2 1 channel
-
Adair, B., Nunn, R., Lewis, S., Dukes, I, Philipson, L., and Yeager, M. (2008). Single particle image reconstruction of the human recombinant Kv2.1 channel. Biophys. J. 94, 2106-2114.
-
(2008)
Biophys. J.
, vol.94
, pp. 2106-2114
-
-
Adair, B.1
Nunn, R.2
Lewis, S.3
Dukes, I.4
Philipson, L.5
Yeager, M.6
-
2
-
-
0033769083
-
The A-type potassium channel Kv4 2 is a substrate for the mitogen-activated protein kinase ERK
-
Adams, J. P., Anderson, A. E., Varga, A. W., Dineley, K. T., Cook, R. G., Pfaffinger, P. J., and Sweatt, J. D. (2000). The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK. J. Neurochem. 75, 2277-2287.
-
(2000)
J. Neurochem.
, vol.75
, pp. 2277-2287
-
-
Adams, J.P.1
Anderson, A.E.2
Varga, A.W.3
Dineley, K.T.4
Cook, R.G.5
Pfaffinger, P.J.6
Sweatt, J.D.7
-
3
-
-
68949094086
-
+ channel exit from the endoplasmic reticulum
-
+ channel exit from the endoplasmic reticulum. J. Biol. Chem. 284, 20668-20675.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 20668-20675
-
-
Alaimo, A.1
Gómez-Posada, J.C.2
Aivar, P.3
Etxeberría, A.4
Rodriguez-Alfaro, J.A.5
Areso, P.6
Villarroel, A.7
-
4
-
-
62549108644
-
Participation of HERG channel cytoplasmic structures on regulation by the G proteincoupled TRH receptor
-
Alonso-Ron, C., Barros, F., Manso, D. G., Gómez-Varela, D., Miranda, P., Carretero, L., Domínguez, P., and de la Peña, P. (2009). Participation of HERG channel cytoplasmic structures on regulation by the G proteincoupled TRH receptor. Pflügers Arch. 457, 1237-1252.
-
(2009)
Pflügers Arch
, vol.457
, pp. 1237-1252
-
-
Alonso-Ron, C.1
Barros, F.2
Manso, D.G.3
Gómez-Varela, D.4
Miranda, P.5
Carretero, L.6
Domínguez, P.7
de la Peña, P.8
-
5
-
-
43849103812
-
Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions
-
Alonso-Ron, C., de la Peña, P., Miranda, P., Domínguez, P., and Barros, F. (2008). Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions. Biophys. J. 94, 3893-3911.
-
(2008)
Biophys. J.
, vol.94
, pp. 3893-3911
-
-
Alonso-Ron, C.1
de la Peña, P.2
Miranda, P.3
Domínguez, P.4
Barros, F.5
-
6
-
-
67349135030
-
Role of intracellular domains in the function of the herg potassium channel
-
Al-Owais, M., Bracey, K., and Wray, D. (2009). Role of intracellular domains in the function of the herg potassium channel. Eur. Biophys. J. 38, 569-576.
-
(2009)
Eur. Biophys. J.
, vol.38
, pp. 569-576
-
-
Al-Owais, M.1
Bracey, K.2
Wray, D.3
-
7
-
-
0034007077
-
Kv4 2 phosphorylation by cyclic AMP-dependent protein kinase
-
Anderson, A. E., Adams, J. P., Qian, Y., Cook, R. G., Pfaffinger, P. J., and Sweatt, J. D. (2000). Kv4.2 phosphorylation by cyclic AMP-dependent protein kinase. J. Biol. Chem. 275, 5337-5346.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5337-5346
-
-
Anderson, A.E.1
Adams, J.P.2
Qian, Y.3
Cook, R.G.4
Pfaffinger, P.J.5
Sweatt, J.D.6
-
8
-
-
0026597932
-
Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cerevisiae
-
Anderson,J. A.,Huprikar,S. S.,Kochian, L. V., Lucas, W. J., and Gaber, R. F. (1992). Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cerevisiae. Proc. Natl.Acad. Sci. U.S.A. 89, 3736-3740.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 3736-3740
-
-
Anderson, J.A.1
Huprikar, S.S.2
Kochian, L.V.3
Lucas, W.J.4
Gaber, R.F.5
-
9
-
-
0032906376
-
+ channel gating by protein phosphorylation: structural switches of the inactivation gate
-
+ channel gating by protein phosphorylation: structural switches of the inactivation gate. Nat. Struct. Biol. 6, 146-150.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 146-150
-
-
Antz, C.1
Bauer, T.2
Kalbacher, H.3
Frank, R.4
Covarrubias, M.5
Kalbitzer, H.R.6
Ruppersberg, J.P.7
Baukrowitz, T.8
Fakler, B.9
-
10
-
-
0031030766
-
NMR structure of inactivation gates from mammalian voltage-dependent potassium channels
-
Antz, C., Geyer, M., Fakler, B., Schott, M. K., Guy, H. R., Frank, R., Ruppersberg, J. P., and Kalbitzer, H. R. (1997). NMR structure of inactivation gates from mammalian voltage-dependent potassium channels. Nature 385, 272-275.
-
(1997)
Nature
, vol.385
, pp. 272-275
-
-
Antz, C.1
Geyer, M.2
Fakler, B.3
Schott, M.K.4
Guy, H.R.5
Frank, R.6
Ruppersberg, J.P.7
Kalbitzer, H.R.8
-
11
-
-
61949377514
-
Targeting ion channels in cancer: a novel frontier in antineoplastic therapy
-
Arcangeli,A., Crociani, O., Lastraioli, E., Masi, A., Pilozzi, S., and Becchetti, A. (2009). Targeting ion channels in cancer: a novel frontier in antineoplastic therapy. Curr. Med. Chem. 16, 66-93.
-
(2009)
Curr. Med. Chem.
, vol.16
, pp. 66-93
-
-
Arcangeli, A.1
Crociani, O.2
Lastraioli, E.3
Masi, A.4
Pilozzi, S.5
Becchetti, A.6
-
12
-
-
0015142234
-
Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons
-
Armstrong, C. M. (1971). Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons. J. Gen. Physiol. 58, 413-437.
-
(1971)
J. Gen. Physiol.
, vol.58
, pp. 413-437
-
-
Armstrong, C.M.1
-
13
-
-
0017743723
-
Inactivation of the sodium channel II. Gating current experiments
-
Armstrong, C. M., and Bezanilla, F. (1977). Inactivation of the sodium channel. II. Gating current experiments. J. Gen. Physiol. 70, 567-590.
-
(1977)
J. Gen. Physiol.
, vol.70
, pp. 567-590
-
-
Armstrong, C.M.1
Bezanilla, F.2
-
14
-
-
0015902531
-
Destruction of sodium conductance inactivation in squid axons perfused with pronase
-
Armstrong, C. M., Bezanilla, F., and Rojas, E. (1973). Destruction of sodium conductance inactivation in squid axons perfused with pronase. J. Gen. Physiol. 62, 375-391.
-
(1973)
J. Gen. Physiol.
, vol.62
, pp. 375-391
-
-
Armstrong, C.M.1
Bezanilla, F.2
Rojas, E.3
-
15
-
-
33645300737
-
From molecule to malady
-
Ashcroft, F. M. (2006). From molecule to malady. Nature 440, 440-447.
-
(2006)
Nature
, vol.440
, pp. 440-447
-
-
Ashcroft, F.M.1
-
16
-
-
78650589673
-
Eag and HERG potassium channels as novel therapeutic targets in cancer
-
Asher, V., Sowter, H., Shaw, R., Bali, A., and Khan, R. (2010). Eag and HERG potassium channels as novel therapeutic targets in cancer. World J. Surg. Oncol. 8, 113.
-
(2010)
World J. Surg. Oncol.
, vol.8
, pp. 113
-
-
Asher, V.1
Sowter, H.2
Shaw, R.3
Bali, A.4
Khan, R.5
-
18
-
-
79952419012
-
Mass spectrometry-based phosphoproteomics reveals multisite phosphorylation of mammalian brain voltage-gated sodium and potassium channels
-
Baek, J.-H., Cerda, O., and Trimmer, J. S. (2011). Mass spectrometry-based phosphoproteomics reveals multisite phosphorylation of mammalian brain voltage-gated sodium and potassium channels. Semin. Cell Dev. Biol. 22, 153-159.
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 153-159
-
-
Baek, J.-H.1
Cerda, O.2
Trimmer, J.S.3
-
19
-
-
32344440232
-
NMR-derived dynamic aspects of N-type inactivation of a Kv channel suggest a transient interaction with the T1 domain
-
Baker,K.A.,Hilty,C.,Peti,W.,Prince,A., Pfaffinger, P. J., Wider, G., Wüthrich, K., and Choe, S. (2006). NMR-derived dynamic aspects of N-type inactivation of a Kv channel suggest a transient interaction with the T1 domain. Biochemistry 45, 1663-1672.
-
(2006)
Biochemistry
, vol.45
, pp. 1663-1672
-
-
Baker, K.A.1
Hilty, C.2
Peti, W.3
Prince, A.4
Pfaffinger, P.J.5
Wider, G.6
Wüthrich, K.7
Choe, S.8
-
22
-
-
62349098199
-
Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of Kv4 2 channels
-
Barghaan, J., and Bähring, R. (2009). Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of Kv4.2 channels. J. Gen. Physiol. 133, 205-224.
-
(2009)
J. Gen. Physiol.
, vol.133
, pp. 205-224
-
-
Barghaan, J.1
Bähring, R.2
-
23
-
-
38949143719
-
Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4 2 channels
-
Barghaan, J., Tozakidou, M., Ehmke, H., and Bähring, R. (2008). Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels. Biophys. J. 94, 1276-1294.
-
(2008)
Biophys. J.
, vol.94
, pp. 1276-1294
-
-
Barghaan, J.1
Tozakidou, M.2
Ehmke, H.3
Bähring, R.4
-
27
-
-
0028195054
-
+ current in resting potential and thyrotropin-releasing hormone-induced changes in cell excitability of GH3 rat anterior pituitary cells
-
+ current in resting potential and thyrotropin-releasing hormone-induced changes in cell excitability of GH3 rat anterior pituitary cells. Pflügers Arch. 426, 221-230.
-
(1994)
Pflügers Arch
, vol.426
, pp. 221-230
-
-
Barros, F.1
Villalobos, C.2
García-Sancho, J.3
del Camino, D.4
de la Peña, P.5
-
30
-
-
0032929808
-
Determinants of potassium channel assembly localized within the cytoplasmic C-terminal domain of Kv2
-
Bentley, G. N., Brooks, M. A., O'Neill, C. A., and Findlay, J. B. (1999). Determinants of potassium channel assembly localized within the cytoplasmic C-terminal domain of Kv2.1. Biochim. Biophys. Acta 1418, 176-184.
-
(1999)
1. Biochim. Biophys. Acta
, vol.1418
, pp. 176-184
-
-
Bentley, G.N.1
Brooks, M.A.2
O'Neill, C.A.3
Findlay, J.B.4
-
31
-
-
39449113300
-
+ channel-drug interactions by ancillary subunits
-
+ channel-drug interactions by ancillary subunits. J. Physiol. 586, 929-950.
-
(2008)
J. Physiol.
, vol.586
, pp. 929-950
-
-
Bett, G.C.L.1
Rasmusson, R.L.2
-
32
-
-
41149095488
-
How membrane proteins sense voltage
-
Bezanilla, F. (2008). How membrane proteins sense voltage. Nat. Rev. Mol. Cell Biol. 9, 323-332.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 323-332
-
-
Bezanilla, F.1
-
33
-
-
0033930875
-
Potassium channel structure: domain by domain
-
Biggin, P. C., Roosild, T., and Choe, S. (2000). Potassium channel structure: domain by domain. Curr. Opin. Struct. Biol. 10, 456-461.
-
(2000)
Curr. Opin. Struct. Biol.
, vol.10
, pp. 456-461
-
-
Biggin, P.C.1
Roosild, T.2
Choe, S.3
-
34
-
-
0032589790
-
+ channels
-
+ channels. Nat. Struct. Biol. 6, 38-43.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 38-43
-
-
Bixby, K.A.1
Nanao, M.H.2
Shen, N.V.3
Kreusch, A.4
Bellamy, H.5
Pfaffinger, P.J.6
Choe, S.7
-
35
-
-
36649017644
-
Role of the S6 C-terminus in KCNQ1 channel gating
-
Boulet, I. R., Labro, A. J., Raes, A. L., and Snyders, D. J. (2007). Role of the S6 C-terminus in KCNQ1 channel gating. J. Physiol. 585, 325-337.
-
(2007)
J. Physiol.
, vol.585
, pp. 325-337
-
-
Boulet, I.R.1
Labro, A.J.2
Raes, A.L.3
Snyders, D.J.4
-
37
-
-
27644491039
-
Contribution of N-and C-terminal Kv4.2 channel domains to KChIP interaction
-
Callsen, B., Isbrandt, D., Sauter, K., Hartmann, L. S., Pongs, O., and Bähring, R. (2005). Contribution of N-and C-terminal Kv4.2 channel domains to KChIP interaction. J. Physiol. 568, 397-412.
-
(2005)
J. Physiol.
, vol.568
, pp. 397-412
-
-
Callsen, B.1
Isbrandt, D.2
Sauter, K.3
Hartmann, L.S.4
Pongs, O.5
Bähring, R.6
-
38
-
-
78650907529
-
Mining recent brain proteomic databases for ion channel phosphosite nuggets
-
Cerda, O., Baek, J.-Y., and Trimmer, J. S. (2010). Mining recent brain proteomic databases for ion channel phosphosite nuggets. J. Gen. Physiol. 137, 3-16.
-
(2010)
J. Gen. Physiol.
, vol.137
, pp. 3-16
-
-
Cerda, O.1
Baek, J.-Y.2
Trimmer, J.S.3
-
39
-
-
78049405427
-
Analysis and functional implications of phosphorylation of neuronal voltage-gated potassium channels
-
Cerda, O., and Trimmer, J. S. (2010). Analysis and functional implications of phosphorylation of neuronal voltage-gated potassium channels. Neurosci. Lett. 486, 60-67.
-
(2010)
Neurosci. Lett.
, vol.486
, pp. 60-67
-
-
Cerda, O.1
Trimmer, J.S.2
-
40
-
-
0035949603
-
The S4- S5 linker couples voltage sensing and activation of pacemaker channels
-
Chen, J., Mitcheson, J. S., Tristani-Firouzi, M., Lin, M., and San-guinetti, M. C. (2001). The S4- S5 linker couples voltage sensing and activation of pacemaker channels. Proc. Natl. Acad. Sci. U.S.A. 98, 11277-11282.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 11277-11282
-
-
Chen, J.1
Mitcheson, J.S.2
Tristani-Firouzi, M.3
Lin, M.4
San-guinetti, M.C.5
-
41
-
-
0033537885
-
Long QT syndrome-associated mutations in the Per-Arnt-sim (PAS) domain of HERG potassium channels accelerate deactivation
-
Chen, J., Zou, A., Splawski, I., Keating, M. T., and Sanguinetti, M. C. (1999). Long QT syndrome-associated mutations in the Per-Arnt-sim (PAS) domain of HERG potassium channels accelerate deactivation. J. Biol. Chem. 274, 10113-10118.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10113-10118
-
-
Chen, J.1
Zou, A.2
Splawski, I.3
Keating, M.T.4
Sanguinetti, M.C.5
-
42
-
-
17744393426
-
HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometrium
-
Cherubini, A., Taddei, G. L., Crociani, O., Paglierani, M., Buccoliero, A. M., Fontana, L., Noci, I., Borri, P., Borrani, E., Giachi, M., Becchetti, A., Rosati, B., Wanke, E., Olivotto, M., and Arcangeli, A. (2000). HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometrium. Br. J. Cancer 83, 1722-1729.
-
(2000)
Br. J. Cancer
, vol.83
, pp. 1722-1729
-
-
Cherubini, A.1
Taddei, G.L.2
Crociani, O.3
Paglierani, M.4
Buccoliero, A.M.5
Fontana, L.6
Noci, I.7
Borri, P.8
Borrani, E.9
Giachi, M.10
Becchetti, A.11
Rosati, B.12
Wanke, E.13
Olivotto, M.14
Arcangeli, A.15
-
44
-
-
24044494280
-
Kv1 5 surface expression is modulated by retrograde trafficking of newly endocytosed channels by the dynein motor
-
Choi, W. S., Khurana, A., Mathur, R., Viswanathan, V., Steele, D. F., and Fedida, D. (2005). Kv1.5 surface expression is modulated by retrograde trafficking of newly endocytosed channels by the dynein motor. Circ. Res. 97, 363-371.
-
(2005)
Circ. Res.
, vol.97
, pp. 363-371
-
-
Choi, W.S.1
Khurana, A.2
Mathur, R.3
Viswanathan, V.4
Steele, D.F.5
Fedida, D.6
-
45
-
-
78650939755
-
KCNQ1 channels voltage dependency through a voltagedependent binding of the S4-S5 linker to the pore domain
-
Choveau, F. S., Rodriguez, N., Ali, F. A., Labro, A. J., Rose, T., Dahimene, S., Boudin, H., Le Henaff, C., Escande, D., Snyders, D. J., Charpentier, F., Merot, J., Baro, I., and Loussouarn, G. (2011). KCNQ1 channels voltage dependency through a voltagedependent binding of the S4-S5 linker to the pore domain. J. Biol. Chem. 286, 707-716.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 707-716
-
-
Choveau, F.S.1
Rodriguez, N.2
Ali, F.A.3
Labro, A.J.4
Rose, T.5
Dahimene, S.6
Boudin, H.7
Le Henaff, C.8
Escande, D.9
Snyders, D.J.10
Charpentier, F.11
Merot, J.12
Baro, I.13
Loussouarn, G.14
-
46
-
-
77953714921
-
Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels
-
Clarke, O. B., Caputo, A. T., Hill, A. P., Vandenberg, J. I., Smith, B. J., and Gulbis, J. M. (2010). Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels. Cell 141, 1018-1029.
-
(2010)
Cell
, vol.141
, pp. 1018-1029
-
-
Clarke, O.B.1
Caputo, A.T.2
Hill, A.P.3
Vandenberg, J.I.4
Smith, B.J.5
Gulbis, J.M.6
-
47
-
-
34249731333
-
Modulation of hERG potassium currents in HEK-293 cells by protein kinase C
-
Cockerill, S. L., Tobin, A. B., Torrecilla, I., Willars, G. B., Standen, N. B., and Mitcheson,J. S. (2007). Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits. J. Physiol. 581, 479-493.
-
(2007)
Evidence for direct phosphorylation of pore forming subunits. J. Physiol.
, vol.581
, pp. 479-493
-
-
Cockerill, S.L.1
Tobin, A.B.2
Torrecilla, I.3
Willars, G.B.4
Standen, N.B.5
Mitcheson, J.S.6
-
48
-
-
0033041656
-
+ channels
-
+ channels. Ann. N. Y. Acad. Sci. 868, 233-2865.
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.868
, pp. 233-2865
-
-
Coetze, W.A.1
Amarillo, Y.2
Chiu, J.3
Chow, A.4
Lau, D.5
McCormack, T.6
Moreno, H.7
Nadal, M.S.8
Ozaita, A.9
Poutney, D.10
Saganich, M.11
VegaSaenz de Miera, E.12
Rudy, B.13
-
49
-
-
0034797512
-
The role of protein phosphorylation in human health and disease
-
Cohen, P. (2001). The role of protein phosphorylation in human health and disease. Eur. J. Biochem. 268, 5001-5010.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 5001-5010
-
-
Cohen, P.1
-
50
-
-
0028605349
-
Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate
-
Covarrubias, M., Wei, A., Salkoff, L., and Vyas, T. B. (1994). Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate. Neuron 13, 1403-1412.
-
(1994)
Neuron
, vol.13
, pp. 1403-1412
-
-
Covarrubias, M.1
Wei, A.2
Salkoff, L.3
Vyas, T.B.4
-
51
-
-
79961111359
-
Where's the gate? Gating in the deep pore of the BKCa channel
-
Cox, D. H., and Hoshi, T. (2011). Where's the gate? Gating in the deep pore of the BKCa channel. J. Gen. Physiol. 238, 133-136.
-
(2011)
J. Gen. Physiol.
, vol.238
, pp. 133-136
-
-
Cox, D.H.1
Hoshi, T.2
-
52
-
-
77954515664
-
+ channels
-
+ channels. Nature 466, 272-275.
-
(2010)
Nature
, vol.466
, pp. 272-275
-
-
Cuello, L.G.1
Joginin, V.2
Cortes, D.M.3
Pan, A.C.4
Gagnon, D.G.5
Dalmas, O.6
Cordero-Morales, J.F.7
Chakrapani, S.8
Roux, B.9
Perozo, E.10
-
53
-
-
0035907235
-
Analysis of the cyclic nucleotide binding domain on the HERG potassium channel and interactions with KCNE2
-
Cui, J., Kagan, A., Qin, D., Mathew, J., Melman, Y., and McDonald, T. V. (2001). Analysis of the cyclic nucleotide binding domain on the HERG potassium channel and interactions with KCNE2. J. Biol. Chem. 276, 17244-17251.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17244-17251
-
-
Cui, J.1
Kagan, A.2
Qin, D.3
Mathew, J.4
Melman, Y.5
McDonald, T.V.6
-
55
-
-
0035370622
-
A discrete amino terminal domain of Kv1 5 and Kv1. 4 potassium channels interacts with the spectrin repeats of alpha-actinin-2
-
Cukovic, D., Lu, G. W., Wible, B., Steele, D. F., and Fedida, D. (2001). A discrete amino terminal domain of Kv1.5 and Kv1.4 potassium channels interacts with the spectrin repeats of alpha-actinin-2. FEBS Lett. 498, 87-92.
-
(2001)
FEBS Lett
, vol.498
, pp. 87-92
-
-
Cukovic, D.1
Lu, G.W.2
Wible, B.3
Steele, D.F.4
Fedida, D.5
-
56
-
-
0034059198
-
Voltage dependent activation of potassium channels is coupled to T1 domain structure
-
Cushman, S. J., Nanao, M. H., Jahng, A. W., DeRubeis, D., Choe, S., and Pfaffinger, P. J. (2000). Voltage dependent activation of potassium channels is coupled to T1 domain structure. Nat. Struct. Biol. 7, 403-407.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 403-407
-
-
Cushman, S.J.1
Nanao, M.H.2
Jahng, A.W.3
DeRubeis, D.4
Choe, S.5
Pfaffinger, P.J.6
-
57
-
-
79956326492
-
Demonstration of physical proximity between the amino terminus and the S4-S5 linker of the hERG potassium channel
-
De la Peña, P., Alonso-Ron, C., Machín, A., Fernández-Trillo, J., Carretero, L., Domínguez, P., and Barros, F. (2011). Demonstration of physical proximity between the amino terminus and the S4-S5 linker of the hERG potassium channel. J. Biol. Chem. 286, 19065-19075.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 19065-19075
-
-
De la Peña, P.1
Alonso-Ron, C.2
Machín, A.3
Fernández-Trillo, J.4
Carretero, L.5
Domínguez, P.6
Barros, F.7
-
58
-
-
1842740890
-
Voltage-dependent gating of hyperpolarization-activated, cyclic nucleotide-gated pacemaker channels. molecular coupling between the S4-S5 and C-linkers
-
Decher,N.,Chen,J.,and Sanguinetti,M. C. (2004). Voltage-dependent gating of hyperpolarization-activated, cyclic nucleotide-gated pacemaker channels. molecular coupling between the S4-S5 and C-linkers. J. Biol. Chem. 279, 13859-13865.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13859-13865
-
-
Decher, N.1
Chen, J.2
Sanguinetti, M.C.3
-
61
-
-
0026757484
-
Okadaic acid and calyculin A enhance the effect of thyrotropinreleasing hormone on GH3 rat anterior pituitary cells excitability
-
Delgado, L. M., de la Peña, P., del Camino, D., and Barros, F. (1992). Okadaic acid and calyculin A enhance the effect of thyrotropinreleasing hormone on GH3 rat anterior pituitary cells excitability. FEBS Lett. 311, 41-45.
-
(1992)
FEBS Lett
, vol.311
, pp. 41-45
-
-
Delgado, L.M.1
de la Peña, P.2
del Camino, D.3
Barros, F.4
-
62
-
-
0026045545
-
+ channel behaves like an openchannel blocker
-
+ channel behaves like an openchannel blocker. Neuron 7, 743-753.
-
(1991)
Neuron
, vol.7
, pp. 743-753
-
-
Demo, S.D.1
Yellen, G.2
-
63
-
-
0037214636
-
Effect of S6 tail mutations on charge movement in Shaker potassium channels
-
Ding, S., and Horn, R. (2003). Effect of S6 tail mutations on charge movement in Shaker potassium channels. Biophys. J. 84, 295-305.
-
(2003)
Biophys. J.
, vol.84
, pp. 295-305
-
-
Ding, S.1
Horn, R.2
-
64
-
-
0028321838
-
+ channel inactivation gating by the cAMP-dependent protein kinase
-
+ channel inactivation gating by the cAMP-dependent protein kinase. Neuron 12, 1097-1109.
-
(1994)
Neuron
, vol.12
, pp. 1097-1109
-
-
Drain, P.1
Dubin, A.E.2
Aldrich, R.W.3
-
65
-
-
0034657769
-
Do glia have heart? Expression and functional role for ether-a-go-go currents in hippocampal astrocytes
-
Emmi, A., Wenzel, H. J., Schwartzkroin, P. A., Taglialatela, M., Castaldo, P., Bianchi, L., Nerbonne, J., Robertson, G. A., and Janigro, D. (2000). Do glia have heart? Expression and functional role for ether-a-go-go currents in hippocampal astrocytes. J. Neurosci. 20, 3915-3925.
-
(2000)
J. Neurosci.
, vol.20
, pp. 3915-3925
-
-
Emmi, A.1
Wenzel, H.J.2
Schwartzkroin, P.A.3
Taglialatela, M.4
Castaldo, P.5
Bianchi, L.6
Nerbonne, J.7
Robertson, G.A.8
Janigro, D.9
-
66
-
-
42049108605
-
Calmodulin regulates the trafficking of KCNQ2 potassium channels
-
Etxeberria, A., Aivar, P., Rodriguez-Alfaro, J. A., Alaimo, A., Villacé, P., Gómez-Posada, J. C., Areso, P., and Villarroel, A. (2007). Calmodulin regulates the trafficking of KCNQ2 potassium channels. FASEB J. 22, 1135-1143.
-
(2007)
FASEB J
, vol.22
, pp. 1135-1143
-
-
Etxeberria, A.1
Aivar, P.2
Rodriguez-Alfaro, J.A.3
Alaimo, A.4
Villacé, P.5
Gómez-Posada, J.C.6
Areso, P.7
Villarroel, A.8
-
67
-
-
80054974935
-
Electrostatic int. 4 channel
-
Fan, Z., Ji, X., Zhang, D., and Xiao, Z. (2012). Electrostatic interaction between inactivation ball and T1-S1 linker region of Kv1.4 channel. Biochim. Biophys. Acta 1818, 55-63.
-
(2012)
Biochim. Biophys. Acta
, vol.1818
, pp. 55-63
-
-
Fan, Z.1
Ji, X.2
Zhang, D.3
Xiao, Z.4
-
68
-
-
33748741544
-
Potassium channels: new targets in cancer therapy
-
Felipe, A., Vicente, R., Villalonga, N., Roura-Ferrer, M., Martínez-Mármol, R., Solé, L., Ferreres, J. C., and Condom, E. (2006). Potassium channels: new targets in cancer therapy. Cancer Detect. Prev. 30, 375-385.
-
(2006)
Cancer Detect. Prev.
, vol.30
, pp. 375-385
-
-
Felipe, A.1
Vicente, R.2
Villalonga, N.3
Roura-Ferrer, M.4
Martínez-Mármol, R.5
Solé, L.6
Ferreres, J.C.7
Condom, E.8
-
71
-
-
4644276334
-
Acquired QT interval prolongation and HERG: implications for drug discovery and development
-
Finlayson, K., Witchel, H. J., McCulloch, J., and Sharkey, J. (2004). Acquired QT interval prolongation and HERG: implications for drug discovery and development. Eur. J. Pharmacol. 500, 129-142.
-
(2004)
Eur. J. Pharmacol.
, vol.500
, pp. 129-142
-
-
Finlayson, K.1
Witchel, H.J.2
McCulloch, J.3
Sharkey, J.4
-
74
-
-
36348965431
-
Regulation of ion transport proteins by membrane phosphoinositides
-
Gamper, N., and Shapiro, M. S. (2007). Regulation of ion transport proteins by membrane phosphoinositides. Nat. Rev. Neurosci. 8, 921-934.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 921-934
-
-
Gamper, N.1
Shapiro, M.S.2
-
75
-
-
64549108500
-
Divide and conquer: high resolution structural information on TRP channel fragments
-
Gaudet, R. (2009). Divide and conquer: high resolution structural information on TRP channel fragments. J. Gen. Physiol. 133, 231-237.
-
(2009)
J. Gen. Physiol.
, vol.133
, pp. 231-237
-
-
Gaudet, R.1
-
76
-
-
0347949634
-
N-type inactivation features of Kv2 4 channel gating
-
Gebauer, M., Isbrandt, D., Sauter, K., Callsen, B., and Nolting, A. (2004). N-type inactivation features of Kv2.4 channel gating. Biophys. J. 86, 210-223.
-
(2004)
Biophys. J.
, vol.86
, pp. 210-223
-
-
Gebauer, M.1
Isbrandt, D.2
Sauter, K.3
Callsen, B.4
Nolting, A.5
-
77
-
-
33646814436
-
KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin
-
Ghosh, S., Nunziato, D. A., and Pitt, G. S. (2006). KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin. Circ. Res. 98, 1048-1054.
-
(2006)
Circ. Res.
, vol.98
, pp. 1048-1054
-
-
Ghosh, S.1
Nunziato, D.A.2
Pitt, G.S.3
-
79
-
-
0037472735
-
Relevance of the proximal domain in the aminoterminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor
-
Gómez-Varela, D., Barros, F., Viloria, C. G., Giráldez, T., Manso, D. G., Dupuy, S. G., Miranda, P., and de la Peña, P. (2003). Relevance of the proximal domain in the aminoterminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor. FEBS Lett. 535, 125-130.
-
(2003)
FEBS Lett
, vol.535
, pp. 125-130
-
-
Gómez-Varela, D.1
Barros, F.2
Viloria, C.G.3
Giráldez, T.4
Manso, D.G.5
Dupuy, S.G.6
Miranda, P.7
de la Peña, P.8
-
81
-
-
80052425130
-
Editing of human Kv1
-
doi:10.1038/ncomms1446
-
Gonzalez, C., Lopez-Rodriguez, A., Srikumar, D., Rosenthal, J. J. C., and Holmgren, M. (2011). Editing of human Kv1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity. Nat. Commun. 2:436. doi:10.1038/ncomms1446
-
(2011)
1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity. Nat. Commun.
, vol.2
-
-
Gonzalez, C.1
Lopez-Rodriguez, A.2
Srikumar, D.3
Rosenthal, J.J.C.4
Holmgren, M.5
-
82
-
-
33846694346
-
Structure prediction for the down state of a potassium channel voltage sensor
-
Grabe, M., Lai, H. C., Jain, M., Jan,Y. N., and Jan, L. Y. (2007). Structure prediction for the down state of a potassium channel voltage sensor. Nature 445, 550-553.
-
(2007)
Nature
, vol.445
, pp. 550-553
-
-
Grabe, M.1
Lai, H.C.2
Jain, M.3
Jan, Y.N.4
Jan, L.Y.5
-
84
-
-
69149108876
-
A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels
-
Gustina, A. S., and Trudeau, M. C. (2009). A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels. Proc. Natl.Acad. Sci. U.S.A. 106, 13082-13087.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 13082-13087
-
-
Gustina, A.S.1
Trudeau, M.C.2
-
85
-
-
79952120982
-
hERG potassium channel gating is mediated by N-and C-terminal region interactions
-
Gustina, A. S., and Trudeau, M. C. (2011). hERG potassium channel gating is mediated by N-and C-terminal region interactions. J. Gen. Physiol. 137, 315-325.
-
(2011)
J. Gen. Physiol.
, vol.137
, pp. 315-325
-
-
Gustina, A.S.1
Trudeau, M.C.2
-
86
-
-
29844437655
-
International Union of Pharmacology LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
-
Gutman, G. A., Chandy, K. G., Grissmer, S., Lazdunski, M., McKinnon, D., Pardo, L. A., Robertson, G. A., Rudy, B., Sanguinetti, M. C., Stühmer, W., and Wang, X. (2005). International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol. Rev. 57, 473-508.
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 473-508
-
-
Gutman, G.A.1
Chandy, K.G.2
Grissmer, S.3
Lazdunski, M.4
McKinnon, D.5
Pardo, L.A.6
Robertson, G.A.7
Rudy, B.8
Sanguinetti, M.C.9
Stühmer, W.10
Wang, X.11
-
88
-
-
44149126774
-
The C-terminus of Kv7 channels: a multifunctional module
-
Haitin, Y., and Attali, B. (2008). The C-terminus of Kv7 channels: a multifunctional module. J. Physiol. 586, 1803-1810.
-
(2008)
J. Physiol.
, vol.586
, pp. 1803-1810
-
-
Haitin, Y.1
Attali, B.2
-
89
-
-
67651151053
-
Intracellular domains interactions and gated motions of IKS potassium channel subunits
-
Haitin, Y., Wiener, R., Shaham, D., Peretz, A., Cohen, E. B., Shamgar, L., Pongs, O., Hirsch, J. A., and Attali, B. (2009). Intracellular domains interactions and gated motions of IKS potassium channel subunits. EMBO J. 28, 1994-2005.
-
(2009)
EMBO J
, vol.28
, pp. 1994-2005
-
-
Haitin, Y.1
Wiener, R.2
Shaham, D.3
Peretz, A.4
Cohen, E.B.5
Shamgar, L.6
Pongs, O.7
Hirsch, J.A.8
Attali, B.9
-
91
-
-
33744800245
-
Modulation of Kv2 1 channel gating and TEA sensitivity by distinct domains of SNAP-25
-
He, Y., Kang, Y., Leung, Y., Xia, F., Gao, X., Xie, H., Gaisano, H. Y., and Tsushima, R. G. (2006). Modulation of Kv2.1 channel gating and TEA sensitivity by distinct domains of SNAP-25. Biochem. J. 396, 363-369.
-
(2006)
Biochem. J.
, vol.396
, pp. 363-369
-
-
He, Y.1
Kang, Y.2
Leung, Y.3
Xia, F.4
Gao, X.5
Xie, H.6
Gaisano, H.Y.7
Tsushima, R.G.8
-
92
-
-
45549107093
-
Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications
-
Hernandez, C. C., Zaika, O., Tolstykh, G. P., and Shapiro, M. S. (2008). Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications. J. Physiol. 586, 1811-1821.
-
(2008)
J. Physiol.
, vol.586
, pp. 1811-1821
-
-
Hernandez, C.C.1
Zaika, O.2
Tolstykh, G.P.3
Shapiro, M.S.4
-
93
-
-
84866027699
-
-
Hille, B. (1992). Ionic Channels of Excitable Membranes. Sunderland, MA: Sinauer.
-
(1992)
-
-
Hille, B.1
-
94
-
-
0033040717
-
N-terminal deletions of rKv1.4 channels affect the voltage dependence of channel availability
-
Höllerer-Beitz, G., Schönherr, R., Koenen, M., and Heinemann, S. H. (1999). N-terminal deletions of rKv1.4 channels affect the voltage dependence of channel availability. Pflügers Arch. 438, 141-146.
-
(1999)
Pflügers Arch
, vol.438
, pp. 141-146
-
-
Höllerer-Beitz, G.1
Schönherr, R.2
Koenen, M.3
Heinemann, S.H.4
-
95
-
-
0029783095
-
N-type inactivation and the S4-S5 region of the Shaker channel
-
Holmgren, M., Jurman, M. E., and Yellen, G. (1996). N-type inactivation and the S4-S5 region of the Shaker channel. J. Gen. Physiol. 108, 195-206.
-
(1996)
J. Gen. Physiol.
, vol.108
, pp. 195-206
-
-
Holmgren, M.1
Jurman, M.E.2
Yellen, G.3
-
96
-
-
0032168179
-
+ channel can be trapped in the open state by an intersubunit metal bridge
-
+ channel can be trapped in the open state by an intersubunit metal bridge. Neuron 21, 617-621.
-
(1998)
Neuron
, vol.21
, pp. 617-621
-
-
Holmgren, M.1
Shin, K.S.2
Yellen, G.3
-
97
-
-
0030956162
-
+ channels: evidence for a trap door mechanism of activation gating
-
+ channels: evidence for a trap door mechanism of activation gating. J. Gen. Physiol. 109, 527-535.
-
(1997)
J. Gen. Physiol.
, vol.109
, pp. 527-535
-
-
Holmgren, M.1
Smith, P.L.2
Yellen, G.3
-
99
-
-
0025224223
-
Biophysical and molecular mechanisms of Shaker potassium channel inactivation
-
Hoshi, T., Zagotta, W. N., and Aldrich, R. W. (1990). Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 250, 533-538.
-
(1990)
Science
, vol.250
, pp. 533-538
-
-
Hoshi, T.1
Zagotta, W.N.2
Aldrich, R.W.3
-
100
-
-
33847091589
-
Structural insight into KCNQ (Kv7) channel assembly and channelopathy
-
Howard, R. J., Clark, K., Holton, J. M., and Minor, D. L. Jr. (2007). Structural insight into KCNQ (Kv7) channel assembly and channelopathy. Neuron 53, 663-675.
-
(2007)
Neuron
, vol.53
, pp. 663-675
-
-
Howard, R.J.1
Clark, K.2
Holton, J.M.3
Minor Jr., D.L.4
-
101
-
-
0027146670
-
Tyrosine kinasedependent suppression of a potassium channel by the G proteincoupled m1 muscarinic acetylcholine receptor
-
Huang, X.-Y., Morielli, A. D., and Peralta, E. G. (1993). Tyrosine kinasedependent suppression of a potassium channel by the G proteincoupled m1 muscarinic acetylcholine receptor. Cell 75,1145-1156.
-
(1993)
Cell
, vol.75
, pp. 1145-1156
-
-
Huang, X.-Y.1
Morielli, A.D.2
Peralta, E.G.3
-
103
-
-
0031038307
-
+ channel inactivation mediated b the concerted action of the cytoplasmic N-and C-terminal domains
-
+ channel inactivation mediated b the concerted action of the cytoplasmic N-and C-terminal domains. Biophys. J. 72, 163-174.
-
(1997)
Biophys. J.
, vol.72
, pp. 163-174
-
-
Jern, H.H.1
Covarrubias, M.2
-
104
-
-
0038076054
-
+ channel
-
+ channel. Nature 423, 33-41.
-
(2003)
Nature
, vol.423
, pp. 33-41
-
-
Jian, Y.1
Lee, A.2
Chen, J.3
Ruta, V.4
Cadene, M.5
Chait, B.T.6
MacKinnon, R.7
-
106
-
-
0030176232
-
Regulation of potassium channels by protein kinases
-
Jonas, E. A., and Kaczmarek, L. K. (1996). Regulation of potassium channels by protein kinases. Curr. Opin. Neurobiol. 6, 318-323.
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 318-323
-
-
Jonas, E.A.1
Kaczmarek, L.K.2
-
107
-
-
0037968706
-
The roles of N-and C-terminal determinants in the activation of the Kv2 1 potassium channel
-
Ju, M., Stevens, L., Leadbitter, E., and Wray, D. (2003). The roles of N-and C-terminal determinants in the activation of the Kv2.1 potassium channel. J. Biol. Chem. 278, 12769-12778.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12769-12778
-
-
Ju, M.1
Stevens, L.2
Leadbitter, E.3
Wray, D.4
-
109
-
-
0036164699
-
+ current is inhibited by beta1adrenoreceptor activation, via protein kinase A-dependent pathways
-
+ current is inhibited by beta1adrenoreceptor activation, via protein kinase A-dependent pathways. Cardiovasc. Res. 53, 355-362.
-
(2002)
Cardiovasc. Res.
, vol.53
, pp. 355-362
-
-
Karle, C.A.1
Zitron, E.2
Zhang, W.3
Kathöfer, S.4
Schoels, W.5
Kiehn, J.6
-
110
-
-
0037314677
-
Leucine/isoleucine zipper coordination of ion channel macromolecular signaling complexes in the heart: roles in inherited arrhythmias
-
Kass, R. S., Kurokawa, J., Marx, S. O., and Marks, A. R. (2003). Leucine/isoleucine zipper coordination of ion channel macromolecular signaling complexes in the heart: roles in inherited arrhythmias. Trends Cardiovasc. Med. 13, 52-56.
-
(2003)
Trends Cardiovasc. Med.
, vol.13
, pp. 52-56
-
-
Kass, R.S.1
Kurokawa, J.2
Marx, S.O.3
Marks, A.R.4
-
111
-
-
0035936798
-
Molecular and cellular mechanisms of cardiac arrhythmias
-
Keating, M. T., and Sanguinetti, M. C. (2001). Molecular and cellular mechanisms of cardiac arrhythmias. Cell 104, 569-580.
-
(2001)
Cell
, vol.104
, pp. 569-580
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
112
-
-
0034468569
-
Regulation of the cardiac repolarizing HERG potassium channel by protein kinase A
-
Kiehn, J. (2000). Regulation of the cardiac repolarizing HERG potassium channel by protein kinase A. Trends Cardiovasc. Med. 10, 205-209.
-
(2000)
Trends Cardiovasc. Med.
, vol.10
, pp. 205-209
-
-
Kiehn, J.1
-
113
-
-
1342333779
-
Three-dimensional structure of Ito: Kv4 2-KChIP2 ion channels by electron microscopy at 21 Å resolution
-
Kim, L. A., Furat, J., Gutierrez, D., Butler, M. H., Xu, S., Golstein, S. A. N., and Grigorieff, N. (2004). Three-dimensional structure of Ito: Kv4.2-KChIP2 ion channels by electron microscopy at 21 Å resolution. Neuron 41, 513-519.
-
(2004)
Neuron
, vol.41
, pp. 513-519
-
-
Kim, L.A.1
Furat, J.2
Gutierrez, D.3
Butler, M.H.4
Xu, S.5
Golstein, S.A.N.6
Grigorieff, N.7
-
116
-
-
33745838194
-
Molecular rearrangements of the Kv2 1 potassium channel termini associated with voltage gating
-
Kobrinsky, E., Stevens, L., Kazmi, Y., and Soldatov, N. M. (2006). Molecular rearrangements of the Kv2.1 potassium channel termini associated with voltage gating. J. Biol. Chem. 281, 19233-19240.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 19233-19240
-
-
Kobrinsky, E.1
Stevens, L.2
Kazmi, Y.3
Soldatov, N.M.4
-
117
-
-
77955731294
-
Cysteine 723 in the C-linker segment confers oxidative inhibition of hERG1 potassium channels
-
Kolbe, K., Schönherr, R., Gessner, G., Sahoo, N., Hoshi, T., and Heinemann, S. H. (2010). Cysteine 723 in the C-linker segment confers oxidative inhibition of hERG1 potassium channels. J. Physiol. 588, 2999-3009.
-
(2010)
J. Physiol.
, vol.588
, pp. 2999-3009
-
-
Kolbe, K.1
Schönherr, R.2
Gessner, G.3
Sahoo, N.4
Hoshi, T.5
Heinemann, S.H.6
-
118
-
-
0030742577
-
+ channel, rat Kv1.4, has two potential domains that could produce rapid inactivation
-
+ channel, rat Kv1.4, has two potential domains that could produce rapid inactivation. J. Biol. Chem. 272, 19333-19338.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19333-19338
-
-
Kondoh, S.1
Ishii, K.2
Nakamura, Y.3
Taira, N.4
-
119
-
-
0032580205
-
Crystal structure of the tetramerization domain of the Shaker potassium channel
-
Kreusch, A., Pfaffinger, P. J., Stevens, C. F.,and Choe,S. (1998). Crystal structure of the tetramerization domain of the Shaker potassium channel. Nature 392, 945-948.
-
(1998)
Nature
, vol.392
, pp. 945-948
-
-
Kreusch, A.1
Pfaffinger, P.J.2
Stevens, C.F.3
Choe, S.4
-
120
-
-
11144245528
-
KChIP3 rescues the functional expression of Shal channel tetramerization mutants
-
Kunjilwar, K., Strang, C., DeRubeis, D., and Pfaffinger, P. J. (2004). KChIP3 rescues the functional expression of Shal channel tetramerization mutants. J. Biol. Chem. 279, 54542-54551.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 54542-54551
-
-
Kunjilwar, K.1
Strang, C.2
DeRubeis, D.3
Pfaffinger, P.J.4
-
121
-
-
0032538558
-
+ channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current
-
+ channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current. J. Biol. Chem. 273, 27231-27235.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27231-27235
-
-
Kupershmidt, S.1
Snyders, D.J.2
Raes, A.3
Roden, D.M.4
-
122
-
-
78650959213
-
The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure
-
Labro, A. J., Boulet, I. R., Choveau, F., Mayeur, E., Bruyns, T., Loussouarn, G., Raes, A. L., and Snyders, D. J. (2011). The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. J. Biol. Chem. 286, 717-725
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 717-725
-
-
Labro, A.J.1
Boulet, I.R.2
Choveau, F.3
Mayeur, E.4
Bruyns, T.5
Loussouarn, G.6
Raes, A.L.7
Snyders, D.J.8
-
123
-
-
59649096789
-
Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by noninteracting residues
-
Labro, A. J., Raes, A. L., Grottesi, A., Van Hoorick, D., Sansom, M. S. P., and Snyders, D. J. (2008). Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by noninteracting residues. J. Gen. Physiol. 132, 667-680.
-
(2008)
J. Gen. Physiol.
, vol.132
, pp. 667-680
-
-
Labro, A.J.1
Raes, A.L.2
Grottesi, A.3
Van Hoorick, D.4
Sansom, M.S.P.5
Snyders, D.J.6
-
124
-
-
0141954276
-
+ channel
-
+ channel. J. Gen. Physiol. 122, 459-469.
-
(2003)
J. Gen. Physiol.
, vol.122
, pp. 459-469
-
-
Latorre, R.1
Olcese, R.2
Basso, C.3
Gonzalez, C.4
Muñoz, F.5
Cosmelli, D.6
Alvarez, O.7
-
125
-
-
0038305443
-
Syntaxin 1A binds to the cytoplasmic C terminus of Kv2 1 to regulate channel gating and trafficking
-
Leung, Y. M., Kang, Y., Gao, X., Xia, F., Xie, H., Sheu, L., Tsuk, S., Lotan, I., Tsushima, R. G., and Gaisano, H. Y. (2003). Syntaxin 1A binds to the cytoplasmic C terminus of Kv2.1 to regulate channel gating and trafficking. J. Biol. Chem. 278,17532-17538
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17532-17538
-
-
Leung, Y.M.1
Kang, Y.2
Gao, X.3
Xia, F.4
Xie, H.5
Sheu, L.6
Tsuk, S.7
Lotan, I.8
Tsushima, R.G.9
Gaisano, H.Y.10
-
126
-
-
0028324395
-
Modulation of ion channels by protein phosphorylation and de phosphorylation
-
Levitan, I. B. (1994). Modulation of ion channels by protein phosphorylation and de phosphorylation. Annu. Rev. Physiol. 56, 193-212.
-
(1994)
Annu. Rev. Physiol.
, vol.56
, pp. 193-212
-
-
Levitan, I.B.1
-
128
-
-
78649713129
-
NMR solution structure of the N-terminal domain of hERG and its interaction with the S4-S5 linker
-
Li, Q., Gayen, S., Chen, A. S., Huang, Q., Raida, M., and Kang, C. (2010). NMR solution structure of the N-terminal domain of hERG and its interaction with the S4-S5 linker. Biochem. Biophys. Res. Commun. 403, 126-132.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.403
, pp. 126-132
-
-
Li, Q.1
Gayen, S.2
Chen, A.S.3
Huang, Q.4
Raida, M.5
Kang, C.6
-
129
-
-
78651392569
-
Intracellular regions of the eag potassium channel play a critical role in generation of voltage-dependent currents
-
Li, Y., Liu, X., Wu, Y., Xu, Z., Li, H., Griffith,L. C.,and Zhou,Y. (2011). Intracellular regions of the eag potassium channel play a critical role in generation of voltage-dependent currents. J. Biol. Chem. 286, 1389-1399.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 1389-1399
-
-
Li, Y.1
Liu, X.2
Wu, Y.3
Xu, Z.4
Li, H.5
Griffith, L.C.6
Zhou, Y.7
-
130
-
-
33646586039
-
Voltage-gated potassium channels: regulation by accessory subunits
-
Li, Y., Um, S. Y., and McDonald, T. V. (2006). Voltage-gated potassium channels: regulation by accessory subunits. Neuroscientist. 12, 199-210.
-
(2006)
Neuroscientist
, vol.12
, pp. 199-210
-
-
Li, Y.1
Um, S.Y.2
McDonald, T.V.3
-
131
-
-
0038580641
-
Negative charges in the transmembrane domains of the HERG K channel are involved in the activation and deactivation gating processes
-
Liu, J., Zhang, M., Jiang, M., and Tseng, G.-N. (2003). Negative charges in the transmembrane domains of the HERG K channel are involved in the activation and deactivation gating processes. J. Gen. Physiol. 121, 599-614.
-
(2003)
J. Gen. Physiol.
, vol.121
, pp. 599-614
-
-
Liu, J.1
Zhang, M.2
Jiang, M.3
Tseng, G.-N.4
-
134
-
-
23244441222
-
Voltage sensor of Kv1 2: structural basis of electromechanical coupling
-
Long, S. B., Campbell, E. B., and Mackinnon, R. (2005b). Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science 309, 903-908.
-
(2005)
Science
, vol.309
, pp. 903-908
-
-
Long, S.B.1
Campbell, E.B.2
Mackinnon, R.3
-
136
-
-
60549089871
-
The voltage dependence of hEag currents is not determined solely by membranespanning domains
-
Lörinczi, E., Napp, J., Contreras-Jurado, C., Pardo, L. A., and Stühmer, W. (2009). The voltage dependence of hEag currents is not determined solely by membranespanning domains. Eur. Biophys. J. 38, 279-284.
-
(2009)
Eur. Biophys. J.
, vol.38
, pp. 279-284
-
-
Lörinczi, E.1
Napp, J.2
Contreras-Jurado, C.3
Pardo, L.A.4
Stühmer, W.5
-
140
-
-
70350502080
-
Rearrangements in the relative orientation of cytoplasmic domains induced by a membraneanchored protein mediate modulations in Kv channel gating
-
Lvov, A., Greitzer, D., Berlin, S., Chikvashvili, D., Tsuk, S., and Lotan, I. (2009). Rearrangements in the relative orientation of cytoplasmic domains induced by a membraneanchored protein mediate modulations in Kv channel gating. J. Biol. Chem. 284, 28276-28291.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28276-28291
-
-
Lvov, A.1
Greitzer, D.2
Berlin, S.3
Chikvashvili, D.4
Tsuk, S.5
Lotan, I.6
-
141
-
-
77955568987
-
Kava7 channelopathies
-
Maljevic, S., Wuttke, T. V., Seebohm, G., and Lerche, H. (2010). Kava7 channelopathies. Pflügers Arch. 460, 277-288.
-
(2010)
Pflügers Arch
, vol.460
, pp. 277-288
-
-
Maljevic, S.1
Wuttke, T.V.2
Seebohm, G.3
Lerche, H.4
-
142
-
-
0037167878
-
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages
-
Männikkö, R., Elinder, F., and Larsson, H. P. (2002). Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages. Nature 419, 837-841.
-
(2002)
Nature
, vol.419
, pp. 837-841
-
-
Männikkö, R.1
Elinder, F.2
Larsson, H.P.3
-
144
-
-
0031835450
-
The N-terminus of the K channel KAT1 controls its voltage-dependent gating by altering the membrane electric field
-
Marten, I., and Hoshi, T. (1998). The N-terminus of the K channel KAT1 controls its voltage-dependent gating by altering the membrane electric field. Biophys. J. 74, 2953-2962.
-
(1998)
Biophys. J.
, vol.74
, pp. 2953-2962
-
-
Marten, I.1
Hoshi, T.2
-
145
-
-
0037127028
-
Requirement of a macromolecular signaling complex for b-adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel
-
Marx, S. O., Kurokawa, J., Reiken, S., Motoike, H., D'Armiento, J., Marks, A. R.,and Kass,R. S. (2002). Requirement of a macromolecular signaling complex for b-adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science 295, 496-499.
-
(2002)
Science
, vol.295
, pp. 496-499
-
-
Marx, S.O.1
Kurokawa, J.2
Reiken, S.3
Motoike, H.4
D'Armiento, J.5
Marks, A.R.6
Kass, R.S.7
-
146
-
-
0037144502
-
+ channel by syntaxin 1A requires the physical interaction of Gβγ with the channel
-
+ channel by syntaxin 1A requires the physical interaction of Gβγ with the channel. J. Biol. Chem. 277, 34909-34917.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34909-34917
-
-
Michaelevski, I.1
Chikvashvili, D.2
Tsuk, S.3
Fili, O.4
Lohse, M.J.5
Singer-Lahat, D.6
Lotan, I.7
-
147
-
-
0035425497
-
Potassium channels: life in the post-structural world
-
Minor, D. L. Jr. (2001). Potassium channels: life in the post-structural world. Curr. Opin. Struct. Biol. 11, 408-414.
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 408-414
-
-
Minor Jr., D.L.1
-
148
-
-
0034268781
-
The polar T1 interface is linked to conformational changes that open the voltagegated potassium channel
-
Minor, D. L., Lin, Y.-F., Mobley, B. C., Avelar, A., Jan, Y. N., Jan, L. Y., and Berger, J. M. (2000). The polar T1 interface is linked to conformational changes that open the voltagegated potassium channel. Cell 102, 657-670.
-
(2000)
Cell
, vol.102
, pp. 657-670
-
-
Minor, D.L.1
Lin, Y.-F.2
Mobley, B.C.3
Avelar, A.4
Jan, Y.N.5
Jan, L.Y.6
Berger, J.M.7
-
149
-
-
23744481306
-
+ channels in GH3 rat anterior pituitary cells
-
+ channels in GH3 rat anterior pituitary cells. J. Physiol. 566, 717-736.
-
(2005)
J. Physiol.
, vol.566
, pp. 717-736
-
-
Miranda, P.1
Giráldez, T.2
de la Peña, P.3
Manso, D.G.4
Alonso-Ron, C.5
Gómez-Varela, D.6
Domínguez, P.7
Barros, F.8
-
150
-
-
51049115964
-
+ channels as a reporter of the in vivo coarse architecture of the cytoplasmic domains
-
+ channels as a reporter of the in vivo coarse architecture of the cytoplasmic domains. Biochim. Biophys. Acta 1783, 1681-1699.
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 1681-1699
-
-
Miranda, P.1
Manso, D.G.2
Barros, F.3
Carretero, L.4
Hughes, T.E.5
Alonso-Ron, C.6
Domínguez, P.7
de la Peña, P.8
-
151
-
-
44949210432
-
Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2 1 channel
-
Mohapatra, D. P., Siino, D. F., and Trimmer, J. S. (2008). Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel. J. Neurosci. 28, 4982-4994.
-
(2008)
J. Neurosci.
, vol.28
, pp. 4982-4994
-
-
Mohapatra, D.P.1
Siino, D.F.2
Trimmer, J.S.3
-
152
-
-
32544451419
-
The Kv2.1 C terminus can autonomously transfer Kv2.1-like phosphorylation-dependent localization, voltage-dependent gating, and muscarinic modulation to diverse Kv channels
-
Mohapatra, D. P., and Trimmer, J. S. (2006). The Kv2.1 C terminus can autonomously transfer Kv2.1-like phosphorylation-dependent localization, voltage-dependent gating, and muscarinic modulation to diverse Kv channels. J. Neurosci. 26, 685-695.
-
(2006)
J. Neurosci.
, vol.26
, pp. 685-695
-
-
Mohapatra, D.P.1
Trimmer, J.S.2
-
153
-
-
0032567106
-
Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain
-
Morais-Cabral, J. H., Lee, A., Cohen, S. L., Chait, B. T., Li, M., and MacKinnon, R. (1998). Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain. Cell 95, 649-655.
-
(1998)
Cell
, vol.95
, pp. 649-655
-
-
Morais-Cabral, J.H.1
Lee, A.2
Cohen, S.L.3
Chait, B.T.4
Li, M.5
MacKinnon, R.6
-
154
-
-
0030729834
-
Phosphorylation of the Kv2 1 channel alters voltage-dependent activation
-
Murakoshi,H.,Shi,G.,Scannevin,R. H., and Trimmer, J. S. (1997). Phosphorylation of the Kv2.1 channel alters voltage-dependent activation. Mol. Pharmacol. 52, 821-828.
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 821-828
-
-
Murakoshi, H.1
Shi, G.2
Scannevin, R.H.3
Trimmer, J.S.4
-
156
-
-
79251559440
-
The N-terminal tail of hERG contains an amphipathic α-helix that regulates channel deactivation
-
doi:10.1371/journal.pone.0016191
-
Ng, C. A., Hunter, M. J., Perry, M. D., Mobli, M., Ke, Y., Kuchel, P. W., King, G. F., Stock, D., and Vandenberg, J. I. (2011). The N-terminal tail of hERG contains an amphipathic α-helix that regulates channel deactivation. PLoS ONE 6, e16191. doi:10.1371/journal.pone.0016191
-
(2011)
PLoS ONE
, vol.6
-
-
Ng, C.A.1
Hunter, M.J.2
Perry, M.D.3
Mobli, M.4
Ke, Y.5
Kuchel, P.W.6
King, G.F.7
Stock, D.8
Vandenberg, J.I.9
-
157
-
-
68949118408
-
Coupling of S4 helix translocation and S6 gating analyzed by molecular-dynamics simulations and mutated Kv channels
-
Nishizawa, M., and Nishizawa, K. (2009). Coupling of S4 helix translocation and S6 gating analyzed by molecular-dynamics simulations and mutated Kv channels. Biophys. J. 97, 90-100.
-
(2009)
Biophys. J.
, vol.97
, pp. 90-100
-
-
Nishizawa, M.1
Nishizawa, K.2
-
158
-
-
77952403905
-
Potassium channel gating: not an open and shut case
-
Norton, R. S., and Gulbis, J. M. (2010). Potassium channel gating: not an open and shut case. Proc. Natl. Acad. Sci. U.S.A. 107, 7623-7624.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 7623-7624
-
-
Norton, R.S.1
Gulbis, J.M.2
-
160
-
-
0034100735
-
HERG-like potassium current regulates the resting membrane potential in glomus cells of the rabbit carotid body
-
Overholt, J. L., Ficker, E., Yang, T., Shams, H., Bright, G. R., and Prabhakar, N. R. (2000). HERG-like potassium current regulates the resting membrane potential in glomus cells of the rabbit carotid body. J. Neurophysiol. 83, 1150-1157.
-
(2000)
J. Neurophysiol.
, vol.83
, pp. 1150-1157
-
-
Overholt, J.L.1
Ficker, E.2
Yang, T.3
Shams, H.4
Bright, G.R.5
Prabhakar, N.R.6
-
162
-
-
17644388821
-
Impaired KCNQ1-KCNE1 and Phosphatidylinositol-4 5-bisphosphate interaction underlies the long QT syndrome
-
Park, K. H., Piron, J., Dahimene, S., Merot, J., Baro, I., Escande, D., and Loussouarn, G. (2005). Impaired KCNQ1-KCNE1 and Phosphatidylinositol-4,5-bisphosphate interaction underlies the long QT syndrome. Circ. Res. 96, 730-739.
-
(2005)
Circ. Res.
, vol.96
, pp. 730-739
-
-
Park, K.H.1
Piron, J.2
Dahimene, S.3
Merot, J.4
Baro, I.5
Escande, D.6
Loussouarn, G.7
-
163
-
-
36749003075
-
Proteomic analysis of Kv2 1 channel phosphorylation sites determining cell background specific differences in function
-
Park, K.-S., Mohapatra, D. P., and Trimmer, J. S. (2007). Proteomic analysis of Kv2.1 channel phosphorylation sites determining cell background specific differences in function. Channels 1, 59-61.
-
(2007)
Channels
, vol.1
, pp. 59-61
-
-
Park, K.-S.1
Mohapatra, D.P.2
Trimmer, J.S.3
-
164
-
-
40349089867
-
Potassium channel phosphorylation in excitable cells: providing dynamic functional variability to a diverse family of ion channels
-
Park, K.-S., Yang, J.-W., Seikel, E., and Trimmer, J. S. (2008). Potassium channel phosphorylation in excitable cells: providing dynamic functional variability to a diverse family of ion channels. Physiology 23, 49-57.
-
(2008)
Physiology
, vol.23
, pp. 49-57
-
-
Park, K.-S.1
Yang, J.-W.2
Seikel, E.3
Trimmer, J.S.4
-
165
-
-
0031306025
-
Contribution of the NH2 terminus of Kv2 1 to channel activation
-
Pascual, J. M., Shieh, C.-C. Kirsch, G. E., and Brown, A. M. (1997). Contribution of the NH2 terminus of Kv2.1 to channel activation. Am. J. Physiol. 273, C1849-C1858.
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Pascual, J.M.1
Shieh, C.-C.2
Kirsch, G.E.3
Brown, A.M.4
-
167
-
-
33750594842
-
Three-dimensional structure of the KchIP1-Kv4 3 T1 complex reveals a cross-shaped octamer
-
Pioletti, M., Findeisen, F., Hura, G. L., and Minor, D. L. Jr. (2006). Three-dimensional structure of the KchIP1-Kv4.3 T1 complex reveals a cross-shaped octamer. Nat. Struct. Mol. Biol. 13, 987-995.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 987-995
-
-
Pioletti, M.1
Findeisen, F.2
Hura, G.L.3
Minor Jr., D.L.4
-
168
-
-
0041836223
-
Gating currents associated with intramembrane charge displacement in HERG potassium channels
-
Piper, D. R., Varghese, A., Sanguinetti, M. C., and Tristani-Firouzi, M. (2003). Gating currents associated with intramembrane charge displacement in HERG potassium channels. Proc. Natl.Acad. Sci. U.S.A. 100, 10534-10539.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 10534-10539
-
-
Piper, D.R.1
Varghese, A.2
Sanguinetti, M.C.3
Tristani-Firouzi, M.4
-
169
-
-
60549107301
-
The domain and conformational organization in potassium voltage-gated ion channels
-
Pischalnikova, A. V., and Sokolova, O. S. (2009). The domain and conformational organization in potassium voltage-gated ion channels. J. Neuroimmune Pharmacol. 4, 71-82.
-
(2009)
J. Neuroimmune Pharmacol.
, vol.4
, pp. 71-82
-
-
Pischalnikova, A.V.1
Sokolova, O.S.2
-
172
-
-
33748125213
-
Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and post-S6
-
Prole, D.L., and Yellen,G. (2006). Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and post-S6. J. Gen. Physiol. 128, 273-282.
-
(2006)
J. Gen. Physiol.
, vol.128
, pp. 273-282
-
-
Prole, D.L.1
Yellen, G.2
-
173
-
-
0032550274
-
+ channels
-
+ channels. Circ. Res. 82, 739-750.
-
(1998)
Circ. Res.
, vol.82
, pp. 739-750
-
-
Rasmusson, R.L.1
Morales, M.J.2
Wang, S.3
Liu, S.4
Campbell, D.L.5
Brahmajothi, M.V.6
Strauss, H.C.7
-
174
-
-
0344492207
-
Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
-
Redfern, W. S., Carlsson, L., Davis, A. S., Lynch, W. G., MacKenzie, I., Palethorpe, S., Siegl, P. K. S., Strang, I., Sullivan, A. T., Wallis, R., Camm, A. J., and Hammond, T. G. (2002). Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. Cardiovasc. Res. 58, 32-45.
-
(2002)
Cardiovasc. Res.
, vol.58
, pp. 32-45
-
-
Redfern, W.S.1
Carlsson, L.2
Davis, A.S.3
Lynch, W.G.4
MacKenzie, I.5
Palethorpe, S.6
Siegl, P.K.S.7
Strang, I.8
Sullivan, A.T.9
Wallis, R.10
Camm, A.J.11
Hammond, T.G.12
-
175
-
-
23644450590
-
Genetics of acquired long QT syndrome
-
Roden, D. M., and Viswanathan, P. C. (2005). Genetics of acquired long QT syndrome. J. Clin. Invest. 115, 2025-2032.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2025-2032
-
-
Roden, D.M.1
Viswanathan, P.C.2
-
176
-
-
0032556879
-
NIP domain prevents N-type inactivation in voltage-gated potassium channels
-
Roeper, J., Sewing, S., Zhang, Y., Sommer, T., Wanner, S. G., and Pongs, O. (1998). NIP domain prevents N-type inactivation in voltage-gated potassium channels. Nature 391, 390-393.
-
(1998)
Nature
, vol.391
, pp. 390-393
-
-
Roeper, J.1
Sewing, S.2
Zhang, Y.3
Sommer, T.4
Wanner, S.G.5
Pongs, O.6
-
178
-
-
0033670058
-
+ channels in firing and release
-
+ channels in firing and release. FASEB J. 14, 2601-2610.
-
(2000)
FASEB J
, vol.14
, pp. 2601-2610
-
-
Rosati, B.1
Marchetti, P.2
Crociani, O.3
Lecchi, M.4
Lupi, R.5
Arcangeli, A.6
Olivotto, M.7
Wanke, E.8
-
179
-
-
0025925342
-
Cloned neuronal IK(A) channels reopen during recovery from inactivation
-
Ruppersberg, J. P., Frank, R., Pongs, O., and Stocker, M. (1991). Cloned neuronal IK(A) channels reopen during recovery from inactivation. Nature 353, 657-660.
-
(1991)
Nature
, vol.353
, pp. 657-660
-
-
Ruppersberg, J.P.1
Frank, R.2
Pongs, O.3
Stocker, M.4
-
180
-
-
33845383109
-
Modulation of HERG gating by a charge cluster in the N-terminal proximal domain
-
Saenen, J. B., Labro, A. J., Raes, A., and Snyders, D. J. (2006). Modulation of HERG gating by a charge cluster in the N-terminal proximal domain. Biophys. J. 91, 4381-4391.
-
(2006)
Biophys. J.
, vol.91
, pp. 4381-4391
-
-
Saenen, J.B.1
Labro, A.J.2
Raes, A.3
Snyders, D.J.4
-
181
-
-
0029002969
-
A mechanistic link between an inherited and an acquired cardiac arrhythmia
-
Sanguinetti, M. C, Jiang, C, Curran, M. E., and Keating, M. T. (1995). A mechanistic link between an inherited and an acquired cardiac arrhythmia. Cell 81, 299-307.
-
(1995)
Cell
, vol.81
, pp. 299-307
-
-
Sanguinetti, M.C.1
Jiang, C.2
Curran, M.E.3
Keating, M.T.4
-
182
-
-
28544432686
-
N type rapid inactivation in human Kv1 4 channels: functional role of a putative C-terminal helx
-
Sankaranarayanan, K.,Varshney,A., and Mathew, M. K. (2005). N type rapid inactivation in human Kv1.4 channels: functional role of a putative C-terminal helx. Mol. Membr. Biol. 22, 389-400.
-
(2005)
Mol. Membr. Biol.
, vol.22
, pp. 389-400
-
-
Sankaranarayanan, K.1
Varshney, A.2
Mathew, M.K.3
-
183
-
-
10744231205
-
+ channels regulate binding to and modulation by KchIP1
-
+ channels regulate binding to and modulation by KchIP1. Neuron 41, 587-598.
-
(2004)
Neuron
, vol.41
, pp. 587-598
-
-
Scannevin, R.H.1
Wang, K.2
Jow, F.3
Megules, J.4
Kopsco, D.C.5
Edris, W.6
Carroll, K.C.7
Lü, Q.8
Xu, W.9
Xu, Z.10
Katz, A.H.11
Olland, S.12
Lin, L.13
Taylor, M.14
Stahl, M.15
Malakian, K.16
Somers, W.17
Mosyak, L.18
Bowlby, M.R.19
Chanda, P.20
Rhodes, K.J.21
more..
-
184
-
-
0342992842
-
The erg-like current in rat lactotrophs
-
Schäfer, R., Wulfsen, I., Behrens, S., Weinsberg, F., Bauer, C. K., and Schwarz, J. R. (1999). The erg-like current in rat lactotrophs. J. Physiol. 518, 401-416.
-
(1999)
J. Physiol.
, vol.518
, pp. 401-416
-
-
Schäfer, R.1
Wulfsen, I.2
Behrens, S.3
Weinsberg, F.4
Bauer, C.K.5
Schwarz, J.R.6
-
185
-
-
4143106715
-
Effects of Kv1 2 intracellular regions on activation of Kv2. 1 channels
-
Scholle, A., Zimmer, T., Koopmann, R., Engeland, B., Pongs, O., and Benndorf, K. (2004). Effects of Kv1.2 intracellular regions on activation of Kv2.1 channels. Biophys. J. 87, 873-882.
-
(2004)
Biophys. J.
, vol.87
, pp. 873-882
-
-
Scholle, A.1
Zimmer, T.2
Koopmann, R.3
Engeland, B.4
Pongs, O.5
Benndorf, K.6
-
186
-
-
0030054878
-
Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel
-
Schönherr, R., and Heinemann, S. H. (1996). Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel. J. Physiol. 493, 635-642.
-
(1996)
J. Physiol.
, vol.493
, pp. 635-642
-
-
Schönherr, R.1
Heinemann, S.H.2
-
188
-
-
59849086876
-
Kv4 2 is a locus for PKC and ERK/MAPK cross-talk
-
Schrader, L. A., Ren, Y., Cheng, F., Bui, D., Sweatt, J. D., and Anderson, A. E. (2009). Kv4.2 is a locus for PKC and ERK/MAPK cross-talk. Biochem. J. 417, 705-715.
-
(2009)
Biochem. J.
, vol.417
, pp. 705-715
-
-
Schrader, L.A.1
Ren, Y.2
Cheng, F.3
Bui, D.4
Sweatt, J.D.5
Anderson, A.E.6
-
189
-
-
0032476018
-
Subunit folding and assembly steps are interspersed during Shaker potassium channel biogenesis
-
Schulteis, C. T., Nagaya, N., and Papazian, D. M. (1998). Subunit folding and assembly steps are interspersed during Shaker potassium channel biogenesis. J. Biol. Chem. 273, 26210-26217.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26210-26217
-
-
Schulteis, C.T.1
Nagaya, N.2
Papazian, D.M.3
-
190
-
-
79955011398
-
Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel
-
Schünke, S., Stoldt, M., Lecher, J., Kaupp, U. B., and Willbold, D. (2011). Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel. Proc. Natl. Acad. Sci. U.S.A. 108, 6121-6126.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 6121-6126
-
-
Schünke, S.1
Stoldt, M.2
Lecher, J.3
Kaupp, U.B.4
Willbold, D.5
-
191
-
-
0026579591
-
Cloning and expression in yeast of a plant potassium ion transport system
-
Sentenac, H., Bonneaud, N., Minet, M., Lacroute,F.,Salmon,J. M.,Gaymard, F., and Grignon, C. (1992). Cloning and expression in yeast of a plant potassium ion transport system. Science 256, 663-665.
-
(1992)
Science
, vol.256
, pp. 663-665
-
-
Sentenac, H.1
Bonneaud, N.2
Minet, M.3
Lacroute, F.4
Salmon, J.M.5
Gaymard, F.6
Grignon, C.7
-
192
-
-
28044453940
-
Expression of a calmodulinbinding KCNQ2 potassium channel fragment modulates neuronal M-current and membrane excitability
-
Shahidullah, M., Santarelli, L. C., Wen, H., and Levitan, I. B. (2005). Expression of a calmodulinbinding KCNQ2 potassium channel fragment modulates neuronal M-current and membrane excitability. Proc. Natl. Acad. Sci. U.S.A. 102, 16454-16459.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 16454-16459
-
-
Shahidullah, M.1
Santarelli, L.C.2
Wen, H.3
Levitan, I.B.4
-
193
-
-
33646810883
-
Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations
-
Shamgar, L., Ma, L., Schmitt, N., Haitin, Y., Peretz, A., Wiener, R., Hirsch, J., Pongs, O., and Atali, B. (2006). Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations. Circ. Res. 98, 1055-1063.
-
(2006)
Circ. Res.
, vol.98
, pp. 1055-1063
-
-
Shamgar, L.1
Ma, L.2
Schmitt, N.3
Haitin, Y.4
Peretz, A.5
Wiener, R.6
Hirsch, J.7
Pongs, O.8
Atali, B.9
-
194
-
-
0030025308
-
The inward rectification mechanism of the HERG cardiac potassium channel
-
Smith, P. L., Baukrowitz, T., and Yellen, G. (1996). The inward rectification mechanism of the HERG cardiac potassium channel. Nature 379, 833-836.
-
(1996)
Nature
, vol.379
, pp. 833-836
-
-
Smith, P.L.1
Baukrowitz, T.2
Yellen, G.3
-
195
-
-
0036097030
-
Fast and slow voltage sensor movements in HERG potassium channels
-
Smith, P. L., and Yellen, G. (2002). Fast and slow voltage sensor movements in HERG potassium channels. J. Gen. Physiol. 119, 275-293.
-
(2002)
J. Gen. Physiol.
, vol.119
, pp. 275-293
-
-
Smith, P.L.1
Yellen, G.2
-
197
-
-
0035078574
-
Threedimensional structure of a voltagegated potassium channel at 2 5 nm resolution
-
Sokolova, O., Kolmakova-Partensky, L., and Grigorieff, N. (2001). Threedimensional structure of a voltagegated potassium channel at 2.5 nm resolution. Structure 9, 215-220.
-
(2001)
Structure
, vol.9
, pp. 215-220
-
-
Sokolova, O.1
Kolmakova-Partensky, L.2
Grigorieff, N.3
-
198
-
-
0029926887
-
Fast inactivation causes rectification of the IKr channel
-
Spector, P. S., Curran, M. E., Zou, A., Keating, M. T., and Sanguinetti, M. C. (1996). Fast inactivation causes rectification of the IKr channel. J. Gen. Physiol. 107, 611-619.
-
(1996)
J. Gen. Physiol.
, vol.107
, pp. 611-619
-
-
Spector, P.S.1
Curran, M.E.2
Zou, A.3
Keating, M.T.4
Sanguinetti, M.C.5
-
199
-
-
62949118937
-
Roles of surface residues of intracellular domains of heag potassium channels
-
Stevens, L., Ju, M., and Wray, D. (2009). Roles of surface residues of intracellular domains of heag potassium channels. Eur. Biophys. J. 38, 523-532.
-
(2009)
Eur. Biophys. J.
, vol.38
, pp. 523-532
-
-
Stevens, L.1
Ju, M.2
Wray, D.3
-
200
-
-
4344686915
-
Molecular basis of slow activation of the human ether-á-go-go related gene potassium channel
-
Subbiah, R. N., Clarke, C. E., Smith, D. J., Zhao, J., Campbell, T. J., and Vandenberg, J. I. (2004). Molecular basis of slow activation of the human ether-á-go-go related gene potassium channel. J. Physiol. 558, 417-431.
-
(2004)
J. Physiol.
, vol.558
, pp. 417-431
-
-
Subbiah, R.N.1
Clarke, C.E.2
Smith, D.J.3
Zhao, J.4
Campbell, T.J.5
Vandenberg, J.I.6
-
202
-
-
20444428008
-
Regulation of ion channels by phosphatidylinositol 4
-
Suh, B., and Hille, B. (2005). Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate. Curr. Opin. Neurobiol. 15, 1-9.
-
(2005)
5-bisphosphate. Curr. Opin. Neurobiol.
, vol.15
, pp. 1-9
-
-
Suh, B.1
Hille, B.2
-
203
-
-
29144477159
-
Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels
-
Surti, T. S., Huang, L., Jan, Y. N., Jan, L. Y., and Cooper, E. C. (2005). Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels. Proc. Natl. Acad. Sci. U.S.A. 102, 17828-17833.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 17828-17833
-
-
Surti, T.S.1
Huang, L.2
Jan, Y.N.3
Jan, L.Y.4
Cooper, E.C.5
-
204
-
-
9944226711
-
Towards a structural view of gating in potassium channels
-
Swartz, K. J. (2004). Towards a structural view of gating in potassium channels. Nat. Rev. Neurosci. 5, 905-916.
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 905-916
-
-
Swartz, K.J.1
-
205
-
-
57749196006
-
Sensing voltage across lipid membranes
-
Swartz, K. J. (2008). Sensing voltage across lipid membranes. Nature 456, 891-897.
-
(2008)
Nature
, vol.456
, pp. 891-897
-
-
Swartz, K.J.1
-
206
-
-
34548499865
-
Structural dynamics in the gating ring of cyclic nucleotidegated ion channels
-
Taraska, J. W., and Zagotta, W. N. (2007). Structural dynamics in the gating ring of cyclic nucleotidegated ion channels. Nat. Struct. Mol. Biol. 14, 854-860.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 854-860
-
-
Taraska, J.W.1
Zagotta, W.N.2
-
207
-
-
0030859332
-
Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment
-
Terlau, H., Heinemann, S. H., Stühmer, W., Pongs, O., and Ludwig, J. (1997). Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment. J. Physiol. 502, 537-543.
-
(1997)
J. Physiol.
, vol.502
, pp. 537-543
-
-
Terlau, H.1
Heinemann, S.H.2
Stühmer, W.3
Pongs, O.4
Ludwig, J.5
-
208
-
-
19944433529
-
Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by α1Aadrenoreceptors
-
Thomas, D., Wu, K., Wimmer, A.B., Zitron, E., Hammerling, B. C., Kathöfer, S., Lueck, S., Bloehs, R., Kreye, V. A. W., Kiehn, J., Katus, H. A., Schoels, W., and Karle, C. A. (2004). Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by α1Aadrenoreceptors. J. Mol. Med. 82, 826-837.
-
(2004)
J. Mol. Med.
, vol.82
, pp. 826-837
-
-
Thomas, D.1
Wu, K.2
Wimmer, A.B.3
Zitron, E.4
Hammerling, B.C.5
Kathöfer, S.6
Lueck, S.7
Bloehs, R.8
Kreye, V.A.W.9
Kiehn, J.10
Katus, H.A.11
Schoels, W.12
Karle, C.A.13
-
209
-
-
0033600758
-
Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A
-
Thomas, D., Zhang, W., Karle, C. A., Kathöfer, S., Schöls, W., Kübler, W., and Kiehn, J. (1999). Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A. J. Biol. Chem. 274, 27457-27462.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27457-27462
-
-
Thomas, D.1
Zhang, W.2
Karle, C.A.3
Kathöfer, S.4
Schöls, W.5
Kübler, W.6
Kiehn, J.7
-
210
-
-
0038771923
-
Regulation of potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein
-
Thomas, D., Zhang, W., Wu, K., Wimmer, A.-B., Gut, B., Wendt-Nordahl, G., Kathöfer, S., Kreye, V. A. W., Katus, H. A., Schoels, W., Kiehn, J., and Karle, C. A. (2003). Regulation of potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein. Cardiovasc. Res. 59, 14-26.
-
(2003)
Cardiovasc. Res.
, vol.59
, pp. 14-26
-
-
Thomas, D.1
Zhang, W.2
Wu, K.3
Wimmer, A.-B.4
Gut, B.5
Wendt-Nordahl, G.6
Kathöfer, S.7
Kreye, V.A.W.8
Katus, H.A.9
Schoels, W.10
Kiehn, J.11
Karle, C.A.12
-
212
-
-
0029007356
-
HERG, a human inward rectifier in the voltage-gated potassium channel family
-
Trudeau, M. C., Warmke, J. W., Ganetzky, B., and Robertson, G. A. (1995). HERG, a human inward rectifier in the voltage-gated potassium channel family. Science 269, 92-95.
-
(1995)
Science
, vol.269
, pp. 92-95
-
-
Trudeau, M.C.1
Warmke, J.W.2
Ganetzky, B.3
Robertson, G.A.4
-
213
-
-
0033521647
-
Receptor protein tyrosine phosphatase α participates in the m1 muscarinic acetylcholine receptordependent regulation of Kv1 2 channel activity
-
Tsai, W., Morielli, A. D., Cachero, T. G., and Peralta, E. G. (1999). Receptor protein tyrosine phosphatase α participates in the m1 muscarinic acetylcholine receptordependent regulation of Kv1.2 channel activity. EMBO J. 18, 109-118.
-
(1999)
EMBO J
, vol.18
, pp. 109-118
-
-
Tsai, W.1
Morielli, A.D.2
Cachero, T.G.3
Peralta, E.G.4
-
215
-
-
80054717695
-
Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels
-
Vacher, H., and Trimmer, J. S. (2011). Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels. Pflügers Arch. 462, 631-643.
-
(2011)
Pflügers Arch
, vol.462
, pp. 631-643
-
-
Vacher, H.1
Trimmer, J.S.2
-
217
-
-
3142704245
-
Arranging the elements of the potassium channel: the T1 domain occludes the cytoplasmic face of the channel
-
Varhsney, A., Chanda, B., and Mathew, M. K. (2004). Arranging the elements of the potassium channel: the T1 domain occludes the cytoplasmic face of the channel. Eur. Biophys. J. 33, 370-376.
-
(2004)
Eur. Biophys. J.
, vol.33
, pp. 370-376
-
-
Varhsney, A.1
Chanda, B.2
Mathew, M.K.3
-
219
-
-
0346041553
-
S4 movement in a mammalian HCN channel
-
Vemana, S., Pandey, S., and Larsson, H. P. (2004). S4 movement in a mammalian HCN channel. J. Gen. Physiol. 123, 21-32.
-
(2004)
J. Gen. Physiol.
, vol.123
, pp. 21-32
-
-
Vemana, S.1
Pandey, S.2
Larsson, H.P.3
-
221
-
-
0033530381
-
Long QT syndromes and torsade de pointes
-
Viskin, S. (1999). Long QT syndromes and torsade de pointes. Lancet 354, 1625-1633.
-
(1999)
Lancet
, vol.354
, pp. 1625-1633
-
-
Viskin, S.1
-
222
-
-
78650973241
-
Mapping the sequence of conformational changes underlying selectivity filter gating in the Kv11 1 potassium channel
-
Wang, D. T., Hill, A. P., Mann, S. A., Tan, P. S., and Vandenberg, J. I. (2011). Mapping the sequence of conformational changes underlying selectivity filter gating in the Kv11.1 potassium channel. Nat. Struct. Mol. Biol. 18, 35-41.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 35-41
-
-
Wang, D.T.1
Hill, A.P.2
Mann, S.A.3
Tan, P.S.4
Vandenberg, J.I.5
-
224
-
-
22244469050
-
Functionally active T1-T1 interfaces revealed by the accessibility of intracellular thiolate groups in Kv4 channels
-
Wang, G., Shahidullah, M., Rocha, C. A., Strang, C., Pfaffinger, P. J., and Covarrubias, M. (2005). Functionally active T1-T1 interfaces revealed by the accessibility of intracellular thiolate groups in Kv4 channels. J. Gen. Physiol. 126, 55-69.
-
(2005)
J. Gen. Physiol.
, vol.126
, pp. 55-69
-
-
Wang, G.1
Shahidullah, M.2
Rocha, C.A.3
Strang, C.4
Pfaffinger, P.J.5
Covarrubias, M.6
-
226
-
-
0031742141
-
Regulation of deactivation by an amino terminal domain in human ether-a-gogo-related gene potassium channels
-
Wang, J., Trudeau, M. C., Zappia, A. M., and Robertson,G.A. (1998). Regulation of deactivation by an amino terminal domain in human ether-a-gogo-related gene potassium channels. J. Gen. Physiol. 112, 637-647.
-
(1998)
J. Gen. Physiol.
, vol.112
, pp. 637-647
-
-
Wang, J.1
Trudeau, M.C.2
Zappia, A.M.3
Robertson, G.A.4
-
227
-
-
70249124205
-
Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy
-
Wang, L., and Sigworth, F. J. (2009). Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy. Nature 461, 242-245.
-
(2009)
Nature
, vol.461
, pp. 242-245
-
-
Wang, L.1
Sigworth, F.J.2
-
228
-
-
0028292927
-
A family of potassium channel genes related to eag in Drosophila and mammals
-
Warmke, J. W., and Ganetzky, B. (1994). A family of potassium channel genes related to eag in Drosophila and mammals. Proc. Natl. Acad. Sci. U.S.A. 91, 3438-3442.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 3438-3442
-
-
Warmke, J.W.1
Ganetzky, B.2
-
230
-
-
0037107123
-
Calmodulin is an auxiliary subunit of KCNQ2/3 potassium channels
-
Wen, H., and Levitan, I. B. (2002). Calmodulin is an auxiliary subunit of KCNQ2/3 potassium channels. J. Neurosci. 22, 7991-8001.
-
(2002)
J. Neurosci.
, vol.22
, pp. 7991-8001
-
-
Wen, H.1
Levitan, I.B.2
-
231
-
-
0037025337
-
Calcium/calmodulindependent protein kinase II phosphorylates and regulates the Drosophila eag potassium channel
-
Whang, Z., Wilson, G. F., and Griffith, L. C. (2002). Calcium/calmodulindependent protein kinase II phosphorylates and regulates the Drosophila eag potassium channel. J. Biol. Chem. 277, 24022-24029.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24022-24029
-
-
Whang, Z.1
Wilson, G.F.2
Griffith, L.C.3
-
232
-
-
41949105973
-
The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction
-
Wiener, R., Haitin, Y., Shamgar, L., Fernández-Alonso, M. C., Martos, A., Chomsky-Hecht, O., Rivas, G., Attali, B., and Hirsch, J. A. (2008). The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction. J. Biol. Chem. 283, 5815-5830.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5815-5830
-
-
Wiener, R.1
Haitin, Y.2
Shamgar, L.3
Fernández-Alonso, M.C.4
Martos, A.5
Chomsky-Hecht, O.6
Rivas, G.7
Attali, B.8
Hirsch, J.A.9
-
233
-
-
0038182556
-
Solution structure and function of the " tandem inactivation domain" of the neuronal A-type potassium channel Kv1
-
Wissmann, R., Bildl, W., Oliver, D., Beyermann, M., Kalbitzer, H. R., Bentrop, D., and Fakler, B. (2003). Solution structure and function of the " tandem inactivation domain" of the neuronal A-type potassium channel Kv1.4. J. Biol. Chem. 278, 16142-16150.
-
(2003)
4. J. Biol. Chem.
, vol.278
, pp. 16142-16150
-
-
Wissmann, R.1
Bildl, W.2
Oliver, D.3
Beyermann, M.4
Kalbitzer, H.R.5
Bentrop, D.6
Fakler, B.7
-
234
-
-
60549108756
-
Intracellular regions of potassium channels: Kv2 1 and heag
-
Wray, D. (2009). Intracellular regions of potassium channels: Kv2.1 and heag. Eur. Biophys. J. 38, 285-292.
-
(2009)
Eur. Biophys. J.
, vol.38
, pp. 285-292
-
-
Wray, D.1
-
235
-
-
73449119314
-
Voltage-gated potassium channels as therapeutic targets
-
Wulff, H., Castle, N. A., and Pardo, L. A. (2009). Voltage-gated potassium channels as therapeutic targets. Nat. Rev. Drug Disc. 8, 982-1001.
-
(2009)
Nat. Rev. Drug Disc.
, vol.8
, pp. 982-1001
-
-
Wulff, H.1
Castle, N.A.2
Pardo, L.A.3
-
236
-
-
59449096598
-
hERG gating micro domains defined by S6 mutagenesis and molecular modeling
-
Wynia-Smith,S. L.,Gillian-Daniel,A. L., Satyshur, K. A., and Robertson, G. A. (2008). hERG gating micro domains defined by S6 mutagenesis and molecular modeling. J. Gen. Physiol. 132, 507-520.
-
(2008)
J. Gen. Physiol.
, vol.132
, pp. 507-520
-
-
Wynia-Smith, S.L.1
Gillian-Daniel, A.L.2
Satyshur, K.A.3
Robertson, G.A.4
-
237
-
-
0028844541
-
Assembly of voltage-gated potassium channels
-
Xu, J., Yu, W., Jan, Y. N., Jan, L. Y., and Li, M. (1995). Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specific interactions between the alpha-subunits. J. Biol. Chem. 270, 24761-24768.
-
(1995)
Conserved hydrophilic motifs determine subfamily-specific interactions between the alpha-subunits. J. Biol. Chem.
, vol.270
, pp. 24761-24768
-
-
Xu, J.1
Yu, W.2
Jan, Y.N.3
Jan, L.Y.4
Li, M.5
-
238
-
-
78649403213
-
Kinesin I transports tetramerized Kv3 channels through the axon initial segment via direct binding
-
Xu, M., Gu, Y., Barry, J., and Gu, C. (2010). Kinesin I transports tetramerized Kv3 channels through the axon initial segment via direct binding. J. Neurosci. 30, 15987-16001.
-
(2010)
J. Neurosci.
, vol.30
, pp. 15987-16001
-
-
Xu, M.1
Gu, Y.2
Barry, J.3
Gu, C.4
-
239
-
-
0035895886
-
Kvbeta subunits increase expression of Kv4
-
Yang, E. K., Alvira, M. R., Levitan, E. S., and Takimoto, K. (2001). Kvbeta subunits increase expression of Kv4.3 channels by interacting with their C termini. J. Biol. Chem. 276, 4839-4844.
-
(2001)
3 channels by interacting with their C termini. J. Biol. Chem.
, vol.276
, pp. 4839-4844
-
-
Yang, E.K.1
Alvira, M.R.2
Levitan, E.S.3
Takimoto, K.4
-
240
-
-
0032417420
-
The moving parts of voltage-gated ion channels
-
Yellen, G. (1998). The moving parts of voltage-gated ion channels. Q. Rev. Biophys. 31, 239-295.
-
(1998)
Q. Rev. Biophys.
, vol.31
, pp. 239-295
-
-
Yellen, G.1
-
241
-
-
0037026489
-
The voltage-gated potassium channels and their relatives
-
Yellen, G. (2002). The voltage-gated potassium channels and their relatives. Nature 419, 35-42.
-
(2002)
Nature
, vol.419
, pp. 35-42
-
-
Yellen, G.1
-
242
-
-
29844433234
-
Overview of molecular relationships in the voltage-gated ion channel superfamily
-
Yu, F. H., Yarov-Yarovoy, V., Gutman, G. A., and Catterall, W. A. (2005). Overview of molecular relationships in the voltage-gated ion channel superfamily. Pharmacol. Rev. 57, 387-395.
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 387-395
-
-
Yu, F.H.1
Yarov-Yarovoy, V.2
Gutman, G.A.3
Catterall, W.A.4
-
243
-
-
0037047394
-
The identification and characterization of noncontinuous calmodulinbinding site in noninactivating voltage-dependent KCNQ potassium channels
-
Yus-Nájera, E., Santana-Castro, I., and Villarroel, A. (2002). The identification and characterization of noncontinuous calmodulinbinding site in noninactivating voltage-dependent KCNQ potassium channels. J. Biol. Chem. 277, 28545-28553.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28545-28553
-
-
Yus-Nájera, E.1
Santana-Castro, I.2
Villarroel, A.3
-
245
-
-
0141831003
-
Structural basis for modulation and agonist specificity of HCN pacemaker channels
-
Zagotta, W. N., Olivier, N. B., Black, K. D., Young, E. C., Olson, R., and Gouaux, E. (2003). Structural basis for modulation and agonist specificity of HCN pacemaker channels. Nature 425, 200-205.
-
(2003)
Nature
, vol.425
, pp. 200-205
-
-
Zagotta, W.N.1
Olivier, N.B.2
Black, K.D.3
Young, E.C.4
Olson, R.5
Gouaux, E.6
-
246
-
-
0037468826
-
PIP2 activates KCNQ channels, and its hydrolysis underlies receptormediated inhibition of M currents
-
Zhang, H., Craciun, L. C., Mirshahi, T., Rohács, T., Lopes, C. M. B., Jin, T., and Logothetis, D. E. (2003). PIP2 activates KCNQ channels, and its hydrolysis underlies receptormediated inhibition of M currents. Neuron 37, 963-975.
-
(2003)
Neuron
, vol.37
, pp. 963-975
-
-
Zhang, H.1
Craciun, L.C.2
Mirshahi, T.3
Rohács, T.4
Lopes, C.M.B.5
Jin, T.6
Logothetis, D.E.7
-
247
-
-
33645122652
-
Interactions between charged residues in the transmembrane segments of the voltage-sensing domain in the hERG channel
-
Zhang, M., Liu, J., Jiang, M., Wu, D.-M., Sonawane, K., Guy, H. R., and Tseng, G.-N. (2005). Interactions between charged residues in the transmembrane segments of the voltage-sensing domain in the hERG channel. J. Membr. Biol. 207, 169-181.
-
(2005)
J. Membr. Biol.
, vol.207
, pp. 169-181
-
-
Zhang, M.1
Liu, J.2
Jiang, M.3
Wu, D.-M.4
Sonawane, K.5
Guy, H.R.6
Tseng, G.-N.7
-
248
-
-
10344246598
-
Gating charges in the activation and inactivation processes of the HERG channel
-
Zhang, M., Liu, J., and Tseng, G.-N. (2004). Gating charges in the activation and inactivation processes of the HERG channel. J. Gen. Physiol. 124, 703-718.
-
(2004)
J. Gen. Physiol.
, vol.124
, pp. 703-718
-
-
Zhang, M.1
Liu, J.2
Tseng, G.-N.3
-
249
-
-
61349135465
-
Length-dependent regulation of the Kv1 2 channel activation by its C-terminus
-
Zhao, L.-L., Wu, A., Bi, L.-J., Liu, P., Zhang, X.-E., Jiang, T., Jin, G., and Qi, Z. (2009). Length-dependent regulation of the Kv1.2 channel activation by its C-terminus. Mol. Membr. Biol. 26, 186-193.
-
(2009)
Mol. Membr. Biol.
, vol.26
, pp. 186-193
-
-
Zhao, L.-L.1
Wu, A.2
Bi, L.-J.3
Liu, P.4
Zhang, X.-E.5
Jiang, T.6
Jin, G.7
Qi, Z.8
-
250
-
-
77953412214
-
Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits
-
Zheng, R., Thompson, K., Obeng-Gymah, E., Alessi, D., Chen, J., Cheng, H., and McDonald, T. V. (2010). Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits. Biochem. J. 428, 75-84.
-
(2010)
Biochem. J.
, vol.428
, pp. 75-84
-
-
Zheng, R.1
Thompson, K.2
Obeng-Gymah, E.3
Alessi, D.4
Chen, J.5
Cheng, H.6
McDonald, T.V.7
-
251
-
-
0035822048
-
Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors
-
Zhou, M., Morais-Cabral, J. H., Mann, S., and MacKinnon, R. (2001). Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature 411, 657-661.
-
(2001)
Nature
, vol.411
, pp. 657-661
-
-
Zhou, M.1
Morais-Cabral, J.H.2
Mann, S.3
MacKinnon, R.4
-
252
-
-
77953722106
-
A twist on potassium channel gating
-
Zhou, W., and Jan, L. (2010). A twist on potassium channel gating. Cell 141, 920-922.
-
(2010)
Cell
, vol.141
, pp. 920-922
-
-
Zhou, W.1
Jan, L.2
-
253
-
-
33644961982
-
+/calmodulin binding to the cytosolic N-and C-termini
-
+/calmodulin binding to the cytosolic N-and C-termini. FEBS J. 273, 1074-1086.
-
(2006)
FEBS J
, vol.273
, pp. 1074-1086
-
-
Ziechner, U.1
Schönherr, R.2
Born, A.3
Gavrilova-Ruch, O.4
Glaser, R.W.5
Malesevic, M.6
Küllertz, G.7
Heinemann, S.H.8
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