The S4-S5 linker couples voltage sensing and activation of pacemaker channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 20, 2001, Pages 11277-11282

  Chen, J ^a   Mitcheson, J S ^a   Tristani Firouzi, M ^a   Lin, M ^a   Sanguinetti, M C ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Ih; Ion channels; Mutagenesis; Xenopus

Indexed keywords

ALANINE; CYCLIC NUCLEOTIDE; GENE PRODUCT; ION CHANNEL; MUTANT PROTEIN; POTASSIUM CHANNEL; PROTEIN HERG; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC POTENTIAL; MEMBRANE DEPOLARIZATION; MUTAGENESIS; NONHUMAN; PACEMAKER; PRIORITY JOURNAL; PROTEIN DOMAIN; REPOLARIZATION; SENSOR; SEQUENCE HOMOLOGY;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BRAIN; CLONING, MOLECULAR; FEMALE; HUMANS; ION CHANNEL GATING; ION CHANNELS; MEMBRANE POTENTIALS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PATCH-CLAMP TECHNIQUES; POINT MUTATION; POTASSIUM CHANNELS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SEQUENCE DELETION; XENOPUS LAEVIS;

ANIMALIA;

EID: 0035949603     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.201250598     Document Type: Article

References (36)