Tight steric closure at the intracellular activation gate of a voltage-gated K+ channel

Neuron

Volumn 32, Issue 4, 2001, Pages 649-656

  Del Camino, Donato ^a   Yellen, Gary ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; POTASSIUM CHANNEL; SILVER;

ARTICLE; CELL ACTIVATION; CHANNEL GATING; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOPLASM; ELECTROSTIMULATION; EXTRACELLULAR SPACE; INTRACELLULAR TRANSPORT; ION TRANSPORT; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY;

EID: 0035923745     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(01)00487-1     Document Type: Article

References (39)

1. +-induced anomalous rectification in squid giant axons
2. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axon
3. Ionic pores, gates, and gating currents
4. The inner quaternary ammonium ion receptor in potassium channels of the node of Ranvier
5. Voltage clamp experiments on internally perfused giant axons
6. Activation-dependent subconductance levels in the drk1 K channel suggest a subunit basis for ion permeation and gating
7. The internal quaternary ammonium receptor site of Shaker potassium channels
8. Blocker protection in the pore of a voltage-gated K+ channel and its structural implications
9. + channel correlate with occupancy of the pore
10. The structure of the potassium channel: Molecular basis of potassium conduction and selectivity
11. Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels
12. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
13. + channel
14. + channels: Evidence for a trap door mechanism of activation gating
15. + channel can be trapped in the open state by an intersubunit metal bridge
16. Biophysical and molecular mechanisms of Shaker potassium channel inactivation
17. The barium site in a potassium channel by x-ray crystallography
18. Visual identification of individual transfected cells for electrophysiology using antibody-coated beads
19. Multiple products of the Drosophila Shaker gene may contribute to potassium channel diversity
20. + channel
21. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels
22. Silver as a probe of pore-forming residues in a potassium channel
23. Potassium blocks barium permeation through a calcium-activated potassium channel
24. + channels
25. + channel studied by EPR spectroscopy
26. Voltage gating of ion channels
27. Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates
28. K+ channels close more slowly in the presence of external K+ and Rb+
29. Anomalous effect of permeant ion concentration on peak open probability of cardiac Na+ channels
30. K channel gating by an affinity switching selectivity filter
31. Position V474 in the S6 of Shaker potassium channels may act as a pivot-point for movements associated with channel opening
32. Immobilisation of gating charge by a substance that simulates inactivation
33. The moving parts of voltage-gated ion channels
34. + channel
35. Selectivity changes during activation of mutant Shaker potassium channels
36. Intermediate conductances during deactivation of heteromultimeric shaker potassium channels
37. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors