KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin

Circulation Research

Volumn 98, Issue 8, 2006, Pages 1048-1054

  Ghosh, Smita ^a   Nunziato, Deborah A ^a   Pitt, Geoffrey S ^a  

^a Columbia University ^*  (United States)

Author keywords

Calmodulin; IKs; KvLQT1; KCNQ1; Long QT syndrome

Indexed keywords

CALCIUM ION; CALMODULIN; ION CHANNEL; POTASSIUM CHANNEL KCNQ1;

ANIMAL CELL; ARTICLE; BACTERIUM; BIOSYNTHESIS; CALCIUM CELL LEVEL; CHANNEL GATING; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GENE LOCUS; GENE MUTATION; LONG QT SYNDROME; NONHUMAN; OOCYTE; PATHOGENESIS; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; STOICHIOMETRY; XENOPUS;

ANIMALS; BINDING SITES; CALCIUM; CALMODULIN; CLONING, MOLECULAR; FEMALE; HUMANS; KCNQ1 POTASSIUM CHANNEL; LONG QT SYNDROME; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; XENOPUS;

EID: 33646814436     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000218863.44140.f2     Document Type: Article

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