Rapid component IKr of the guinea-pig cardiac delayed rectifier K+ current is inhibited by β1-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways

Cardiovascular Research

Volumn 53, Issue 2, 2002, Pages 355-362

  Karle, Christoph A ^a   Zitron, Edgar ^a   Zhang, Wei ^a   Kathöfer, Sven ^a   Schoels, Wolfgang ^a   Kiehn, Johann ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Adrenergic (ant)agonists; Antiarrhythmic agents; K channel; Protein kinases

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CGP 207120A; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; FORSKOLIN; ISOPRENALINE; KT 5720; POTASSIUM ION; UNCLASSIFIED DRUG; XAMOTEROL;

ANIMAL CELL; ANTIARRHYTHMIC ACTIVITY; ARRHYTHMOGENESIS; ARTICLE; CATALYST; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GUINEA PIG; HEART DISEASE; HEART VENTRICLE; IC 50; MUSCLE CELL; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RECEPTOR BLOCKING;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CARBAZOLES; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEPRESSION, CHEMICAL; ENZYME INHIBITORS; FORSKOLIN; GUINEA PIGS; IMIDAZOLES; INDOLES; ISOPROTERENOL; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PYRROLES; XAMOTEROL;

EID: 0036164699     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(01)00509-0     Document Type: Article

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