-
1
-
-
33644891605
-
Phosphorylation and protonation of neighboring MiRP2 sites: Function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis
-
2
-
GW Abbott MH Butler SA Goldstein 2006 Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis FASEB J 20 2 293 301
-
(2006)
FASEB J
, vol.20
, pp. 293-301
-
-
Abbott, G.W.1
Butler, M.H.2
Goldstein, S.A.3
-
2
-
-
44049102683
-
Single particle image reconstruction of the human, recombinant Kv2.1 channel
-
6
-
B Adair R Nunn S Lewis I Dukes L Philipson M Yeager 2008 Single particle image reconstruction of the human, recombinant Kv2.1 channel Biophys J 94 6 2106 2114
-
(2008)
Biophys J
, vol.94
, pp. 2106-2114
-
-
Adair, B.1
Nunn, R.2
Lewis, S.3
Dukes, I.4
Philipson, L.5
Yeager, M.6
-
3
-
-
36248946187
-
Portability of paddle motif function and pharmacology in voltage sensors
-
7168
-
AA Alabi MI Bahamonde HJ Jung JI Kim KJ Swartz 2007 Portability of paddle motif function and pharmacology in voltage sensors Nature 450 7168 370 375
-
(2007)
Nature
, vol.450
, pp. 370-375
-
-
Alabi, A.A.1
Bahamonde, M.I.2
Jung, H.J.3
Kim, J.I.4
Swartz, K.J.5
-
4
-
-
0033816581
-
Tissue-specific effects of sulfonylureas: Lessons from studies of cloned K(ATP) channels
-
4
-
FM Ashcroft FM Gribble 2000 Tissue-specific effects of sulfonylureas: lessons from studies of cloned K(ATP) channels J Diabetes Its Complicat 4 4 192 196
-
(2000)
J Diabetes Its Complicat
, vol.4
, pp. 192-196
-
-
Ashcroft, F.M.1
Gribble, F.M.2
-
5
-
-
38949143719
-
Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels
-
4
-
J Barghaan M Tozakidou H Ehmke R Bähring 2008 Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels Biophys J 94 4 1276 1294
-
(2008)
Biophys J
, vol.94
, pp. 1276-1294
-
-
Barghaan, J.1
Tozakidou, M.2
Ehmke, H.3
Bähring, R.4
-
7
-
-
0028124225
-
Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1
-
DL Browne ST Gancher JG Nutt ER Brunt EA Smith P Kramer 1994 Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1 Nat Genet 8 136 140
-
(1994)
Nat Genet
, vol.8
, pp. 136-140
-
-
Browne, D.L.1
Gancher, S.T.2
Nutt, J.G.3
Brunt, E.R.4
Smith, E.A.5
Kramer, P.6
-
8
-
-
0032567106
-
Crystal structure and functional analysis of the HERG potassium channel N terminus: A eukaryotic PAS domain
-
JHM Cabral A Lee SL Cohen BT Chait M Li R Mackinnon 1998 Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain Cell 95 649 655
-
(1998)
Cell
, vol.95
, pp. 649-655
-
-
Cabral, J.H.M.1
Lee, A.2
Cohen, S.L.3
Chait, B.T.4
Li, M.5
MacKinnon, R.6
-
10
-
-
0036361382
-
Excitability is mediated by the T1 domain of the voltage-gated potassium channel
-
S Choe S Cushman KA Baker P Pfaffinger 2002 Excitability is mediated by the T1 domain of the voltage-gated potassium channel Novartis Found Symp 245 169 175
-
(2002)
Novartis Found Symp
, vol.245
, pp. 169-175
-
-
Choe, S.1
Cushman, S.2
Baker, K.A.3
Pfaffinger, P.4
-
11
-
-
0035907235
-
Analysis of the cyclic nucleotide binding domain of the HERG potassium channel and interactions with KCNE2
-
20
-
J Cui A Kagan D Qin J Mathew YF Melman TV McDonald 2001 Analysis of the cyclic nucleotide binding domain of the HERG potassium channel and interactions with KCNE2 J Biol Chem 276 20 17244 17251
-
(2001)
J Biol Chem
, vol.276
, pp. 17244-17251
-
-
Cui, J.1
Kagan, A.2
Qin, D.3
Mathew, J.4
Melman, Y.F.5
McDonald, T.V.6
-
13
-
-
33751538282
-
Constraints on voltage sensor movement in the shaker K+ channel
-
6
-
RB Darman AA Ivy V Ketty RO Blaustein 2006 Constraints on voltage sensor movement in the shaker K+ channel J Gen Physiol 128 6 687 699
-
(2006)
J Gen Physiol
, vol.128
, pp. 687-699
-
-
Darman, R.B.1
Ivy, A.A.2
Ketty, V.3
Blaustein, R.O.4
-
14
-
-
0028343497
-
The brain Kv1.1 potassium channel: In vitro and in vivo studies on subunit assembly and posttranslational processing
-
3 Pt 2
-
KK Deal DM Lovinger MM Tamkun 1994 The brain Kv1.1 potassium channel: in vitro and in vivo studies on subunit assembly and posttranslational processing J Neurosci 14 3 Pt 2 1666 1676
-
(1994)
J Neurosci
, vol.14
, pp. 1666-1676
-
-
Deal, K.K.1
Lovinger, D.M.2
Tamkun, M.M.3
-
16
-
-
42049108605
-
Calmodulin regulates the trafficking of KCNQ2 potassium channels
-
4
-
A Etxeberria P Aivar JA Rodriguez-Alfaro A Alaimo P Villace JC Gomez-Posada P Areso A Villaroel 2008 Calmodulin regulates the trafficking of KCNQ2 potassium channels FASEB J 22 4 1135 1143
-
(2008)
FASEB J
, vol.22
, pp. 1135-1143
-
-
Etxeberria, A.1
Aivar, P.2
Rodriguez-Alfaro, J.A.3
Alaimo, A.4
Villace, P.5
Gomez-Posada, J.C.6
Areso, P.7
Villaroel, A.8
-
17
-
-
0038502077
-
Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels. Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels
-
1
-
N Gamper MS Shapiro 2003 Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels. Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels J Gen Physiol 122 1 17 31
-
(2003)
J Gen Physiol
, vol.122
, pp. 17-31
-
-
Gamper, N.1
Shapiro, M.S.2
-
18
-
-
33646814436
-
KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin
-
8
-
S Ghosh DA Nunziato GS Pitt 2006 KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin Circ Res 98 8 1048 1054
-
(2006)
Circ Res
, vol.98
, pp. 1048-1054
-
-
Ghosh, S.1
Nunziato, D.A.2
Pitt, G.S.3
-
19
-
-
0034617121
-
Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels
-
5476
-
JM Gulbis M Zhou S Mann R MacKinnon 2000 Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels Science 289 5476 123 127
-
(2000)
Science
, vol.289
, pp. 123-127
-
-
Gulbis, J.M.1
Zhou, M.2
Mann, S.3
MacKinnon, R.4
-
20
-
-
29844437655
-
International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
-
4
-
GA Gutman KG Chandy S Grissmer M Lazdunski D McKinnon LA Pardo 2005 International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels Pharmacol Rev 57 4 473 508
-
(2005)
Pharmacol Rev
, vol.57
, pp. 473-508
-
-
Gutman, G.A.1
Chandy, K.G.2
Grissmer, S.3
Lazdunski, M.4
McKinnon, D.5
Pardo, L.A.6
-
21
-
-
44149126774
-
The C-terminus of Kv7 channels: A multifunctional modules
-
7
-
Y Haitin B Attali 2008 The C-terminus of Kv7 channels: a multifunctional modules J Phisiol 586 7 1803 1810
-
(2008)
J Phisiol
, vol.586
, pp. 1803-1810
-
-
Haitin, Y.1
Attali, B.2
-
22
-
-
33750390132
-
Overexpression of Eag1 potassium channels in clinical tumours
-
B Hemmerlein RM Weseloh F Mello de Queiroz H KnTse Cyrillic signtgen A SCyrillic small letter BEnchez ME Rubio S Martin T Schliephacke M Jenke Heinz-Joachim-Radzun W Sthmer LA Pardo 2006 Overexpression of Eag1 potassium channels in clinical tumours Mol Cancer 5 41
-
(2006)
Mol Cancer
, vol.5
, pp. 41
-
-
Hemmerlein, B.1
Weseloh, R.M.2
Mello De Queiroz, F.3
Kntse Cyrillic Signtgen, H.4
Scyrillic Small Letter Benchez, A.5
Rubio, M.E.6
Martin, S.7
Schliephacke, T.8
Jenke, M.9
Heinz-Joachim-Radzun10
Sthmer, W.11
Pardo, L.A.12
-
24
-
-
0025224223
-
Biophysical and molecular mechanisms of Shaker potassium channel inactivation
-
4980
-
T Hoshi WN Zagotta RW Aldrich 1990 Biophysical and molecular mechanisms of Shaker potassium channel inactivation Science 250 4980 533 538
-
(1990)
Science
, vol.250
, pp. 533-538
-
-
Hoshi, T.1
Zagotta, W.N.2
Aldrich, R.W.3
-
25
-
-
33847091589
-
Structural insight into KCNQ (Kv7) channel assembly and channelopathy
-
5
-
RJ Howard KA Clark JM Holton DL Minor Jr 2007 Structural insight into KCNQ (Kv7) channel assembly and channelopathy Neuron 53 5 663 675
-
(2007)
Neuron
, vol.53
, pp. 663-675
-
-
Howard, R.J.1
Clark, K.A.2
Holton, J.M.3
Minor Jr., D.L.4
-
26
-
-
34848869371
-
Primary episodic ataxias: Diagnosis, pathogenesis and treatment
-
10
-
JC Jen TD Graves EJ Hess MG Hanna RC Griggs RW Baloh 2007 Primary episodic ataxias: diagnosis, pathogenesis and treatment Brain 130 10 2484 2493
-
(2007)
Brain
, vol.130
, pp. 2484-2493
-
-
Jen, J.C.1
Graves, T.D.2
Hess, E.J.3
Hanna, M.G.4
Griggs, R.C.5
Baloh, R.W.6
-
28
-
-
0038752614
-
The principle of gating charge movement in a voltage-dependent K+ channel
-
6935
-
Y Jiang V Ruta J Chen A Lee R MacKinnon 2003 The principle of gating charge movement in a voltage-dependent K+ channel Nature 423 6935 42 48
-
(2003)
Nature
, vol.423
, pp. 42-48
-
-
Jiang, Y.1
Ruta, V.2
Chen, J.3
Lee, A.4
MacKinnon, R.5
-
29
-
-
0035834445
-
Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2
-
PA Jones SJ Tucker FM Ashcroft 2001 Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2 FEBS 508 85 89
-
(2001)
FEBS
, vol.508
, pp. 85-89
-
-
Jones, P.A.1
Tucker, S.J.2
Ashcroft, F.M.3
-
30
-
-
0037205738
-
Molecular identification and characterisation of the human eag2 potassium channel
-
1-3
-
M Ju D Wray 2002 Molecular identification and characterisation of the human eag2 potassium channel FEBS Lett 524 1-3 204 210
-
(2002)
FEBS Lett
, vol.524
, pp. 204-210
-
-
Ju, M.1
Wray, D.2
-
31
-
-
0037968706
-
The roles of N- and C-terminal determinants in the activation of the Kv2.1 potassium channel
-
15
-
M Ju L Stevens E Leadbitter D Wray 2003 The roles of N- and C-terminal determinants in the activation of the Kv2.1 potassium channel J Biol Chem 278 15 12769 12778
-
(2003)
J Biol Chem
, vol.278
, pp. 12769-12778
-
-
Ju, M.1
Stevens, L.2
Leadbitter, E.3
Wray, D.4
-
32
-
-
0035936798
-
Molecular and cellular mechanisms of cardiac arrhythmias
-
4
-
MT Keating MC Sanguinetti 2001 Molecular and cellular mechanisms of cardiac arrhythmias Cell 104 4 569 580
-
(2001)
Cell
, vol.104
, pp. 569-580
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
33
-
-
1342333779
-
Three-dimensional structure of Ito: Kv4.2-KChIP2 ion channels by electron microscopy at 21Ǎ resolution
-
LA Kim J Furst D Gutierrez MH Butler S Xu 2004 Three-dimensional structure of Ito: Kv4.2-KChIP2 ion channels by electron microscopy at 21Ǎ resolution Neuron 4 513 519
-
(2004)
Neuron
, vol.4
, pp. 513-519
-
-
Kim, L.A.1
Furst, J.2
Gutierrez, D.3
Butler, M.H.4
Xu, S.5
-
34
-
-
0032758890
-
K+ channels lacking the 'tetramerization' domain: Implications for pore structure
-
12
-
WR Kobertz C Miller 1999 K+ channels lacking the 'tetramerization' domain: implications for pore structure Nat Struct Biol 6 12 1122 1125
-
(1999)
Nat Struct Biol
, vol.6
, pp. 1122-1125
-
-
Kobertz, W.R.1
Miller, C.2
-
35
-
-
33745838194
-
Molecular rearrangements of the Kv2.1 potassium channel termini associated with voltage gating
-
28
-
E Kobrinsky L Stevens Y Kazmi D Wray NM Soldatov 2006 Molecular rearrangements of the Kv2.1 potassium channel termini associated with voltage gating J Biol Chem 281 28 19233 19240
-
(2006)
J Biol Chem
, vol.281
, pp. 19233-19240
-
-
Kobrinsky, E.1
Stevens, L.2
Kazmi, Y.3
Wray, D.4
Soldatov, N.M.5
-
36
-
-
0032580205
-
Crystal structure of the tetramerization domain of the Shaker potassium channel
-
6679
-
A Kreusch PJ Pfaffinger CF Stevens S Choe 1998 Crystal structure of the tetramerization domain of the Shaker potassium channel Nature 392 6679 945 948
-
(1998)
Nature
, vol.392
, pp. 945-948
-
-
Kreusch, A.1
Pfaffinger, P.J.2
Stevens, C.F.3
Choe, S.4
-
38
-
-
33847081630
-
Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6
-
4
-
Y Kwon T Hofmann C Montell 2007 Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6 Mol Cell 25 4 491 503
-
(2007)
Mol Cell
, vol.25
, pp. 491-503
-
-
Kwon, Y.1
Hofmann, T.2
Montell, C.3
-
39
-
-
33745594600
-
The distribution and targeting of neuronal voltage-gated ion channels
-
7
-
HC Lai LY Jan 2006 The distribution and targeting of neuronal voltage-gated ion channels Nat Rev Neurosci 7 7 548 562
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 548-562
-
-
Lai, H.C.1
Jan, L.Y.2
-
40
-
-
36749038818
-
Voltage-gated ion channels, new targets in anti-cancer research
-
2
-
JY Le Guennec H Ouadid-Ahidouch O Soriani P Besson A Ahidouch C Vandier 2007 Voltage-gated ion channels, new targets in anti-cancer research Recent Patents Anticancer Drug Discov 2 2 189 202
-
(2007)
Recent Patents Anticancer Drug Discov
, vol.2
, pp. 189-202
-
-
Le Guennec, J.Y.1
Ouadid-Ahidouch, H.2
Soriani, O.3
Besson, P.4
Ahidouch, A.5
Vandier, C.6
-
41
-
-
27344442574
-
Structure of the KvAP voltage-dependent K + channel and its dependence on the lipid membrane
-
43
-
SY Lee A Lee J Chen R MacKinnon 2005 Structure of the KvAP voltage-dependent K + channel and its dependence on the lipid membrane Proc Natl Acad Sci USA 102 43 15441 15446
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15441-15446
-
-
Lee, S.Y.1
Lee, A.2
Chen, J.3
MacKinnon, R.4
-
42
-
-
33646586039
-
Voltage-gated potassium channels: Regulation by accessory subunits
-
3
-
Y Li SY Um TV McDonald 2006 Voltage-gated potassium channels: regulation by accessory subunits Neuroscientist 12 3 199 210
-
(2006)
Neuroscientist
, vol.12
, pp. 199-210
-
-
Li, Y.1
Um, S.Y.2
McDonald, T.V.3
-
43
-
-
23244456428
-
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
-
5736
-
SB Long EB Campbell R Mackinnon 2005 Crystal structure of a mammalian voltage-dependent Shaker family K+ channel Science 309 5736 897 903
-
(2005)
Science
, vol.309
, pp. 897-903
-
-
Long, S.B.1
Campbell, E.B.2
MacKinnon, R.3
-
44
-
-
23244441222
-
Voltage sensor of Kv1.2: Structural basis of electromechanical coupling
-
5736
-
SB Long EB Campbell R Mackinnon 2005 Voltage sensor of Kv1.2: structural basis of electromechanical coupling Science 309 5736 903 908
-
(2005)
Science
, vol.309
, pp. 903-908
-
-
Long, S.B.1
Campbell, E.B.2
MacKinnon, R.3
-
45
-
-
36248982122
-
Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment
-
7168
-
SB Long X Tao EB Campbell R MacKinnon 2007 Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment Nature 450 7168 376 382
-
(2007)
Nature
, vol.450
, pp. 376-382
-
-
Long, S.B.1
Tao, X.2
Campbell, E.B.3
MacKinnon, R.4
-
46
-
-
0035909067
-
T1-T1 interactions occur in ER membranes while nascent Kv peptides are still attached to ribosomes
-
J Lu JM Robinson D Edwards C Deutsch 2001 T1-T1 interactions occur in ER membranes while nascent Kv peptides are still attached to ribosomes Biochemistry 40 10934 10946
-
(2001)
Biochemistry
, vol.40
, pp. 10934-10946
-
-
Lu, J.1
Robinson, J.M.2
Edwards, D.3
Deutsch, C.4
-
47
-
-
0030840331
-
Carboxy-terminal domain mediates assembly of the voltage-gated rat ether-a-go-go potassium channel
-
J Ludwig D Owen O Pongs 1997 Carboxy-terminal domain mediates assembly of the voltage-gated rat ether-a-go-go potassium channel EMBO J 16 6337 6345
-
(1997)
EMBO J
, vol.16
, pp. 6337-6345
-
-
Ludwig, J.1
Owen, D.2
Pongs, O.3
-
48
-
-
0034900568
-
Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion
-
8
-
PE MacDonald XF Ha J Wang SR Smukler AM Sun HY Gaisano AM Salapatek PH Backx MB Wheeler 2001 Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion Mol Endocrinol 15 8 1423 1435
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1423-1435
-
-
MacDonald, P.E.1
Ha, X.F.2
Wang, J.3
Smukler, S.R.4
Sun, A.M.5
Gaisano, H.Y.6
Salapatek, A.M.7
Backx, P.H.8
Wheeler, M.B.9
-
49
-
-
0347785490
-
Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion
-
47
-
PE MacDonald S Sewing J Wang JW Joseph SR Smukler G Sakellaropoulos J Wang MC Saleh CB Chan RG Tsushima AM Salapatek MB Wheeler 2002 Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion J Biol Chem 277 47 44938 449345
-
(2002)
J Biol Chem
, vol.277
, pp. 44938-449345
-
-
MacDonald, P.E.1
Sewing, S.2
Wang, J.3
Joseph, J.W.4
Smukler, S.R.5
Sakellaropoulos, G.6
Wang, J.7
Saleh, M.C.8
Chan, C.B.9
Tsushima, R.G.10
Salapatek, A.M.11
Wheeler, M.B.12
-
50
-
-
33745617904
-
Intrinsically disordered C-terminal segments of voltage-activated potassium channels: A possible fishing rod-like mechanism for channel binding to scaffold proteins
-
13
-
E Magidovich SJ Fleishman O Yifrach 2006 Intrinsically disordered C-terminal segments of voltage-activated potassium channels: a possible fishing rod-like mechanism for channel binding to scaffold proteins Bioinformatics 22 13 1546 1550
-
(2006)
Bioinformatics
, vol.22
, pp. 1546-1550
-
-
Magidovich, E.1
Fleishman, S.J.2
Yifrach, O.3
-
51
-
-
34548757819
-
Intrinsic disorder in the C-terminal domain of the Shaker voltage-activated K+ channel modulates its interaction with scaffold proteins
-
32
-
E Magidovich I Orr D Fass U Abdu O Yifrach 2007 Intrinsic disorder in the C-terminal domain of the Shaker voltage-activated K+ channel modulates its interaction with scaffold proteins Proc Natl Acad Sci USA 104 32 13022 13027
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13022-13027
-
-
Magidovich, E.1
Orr, I.2
Fass, D.3
Abdu, U.4
Yifrach, O.5
-
53
-
-
0031835450
-
The N-terminus of the K channel KAT1 controls its voltage-dependent gating by altering the membrane electric field
-
I Marten T Hoshi 1998 The N-terminus of the K channel KAT1 controls its voltage-dependent gating by altering the membrane electric field Biophys J 74 2953 2962
-
(1998)
Biophys J
, vol.74
, pp. 2953-2962
-
-
Marten, I.1
Hoshi, T.2
-
54
-
-
0034268781
-
The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel
-
DL Minor Jr Y-F Lin BC Mobley A Avelar YN Jan LY Jan 2000 The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel Cell 102 657 670
-
(2000)
Cell
, vol.102
, pp. 657-670
-
-
Minor Jr., D.L.1
Lin, Y.-F.2
Mobley, B.C.3
Avelar, A.4
Jan, Y.N.5
Jan, L.Y.6
-
55
-
-
30644461158
-
Calcium- and metabolic state-dependent modulation of the voltage-dependent Kv2.1 channel regulates neuronal excitability in response to ischemia
-
48
-
H Misonou DP Mohapatra M Menegola JS Trimmer 2005 Calcium- and metabolic state-dependent modulation of the voltage-dependent Kv2.1 channel regulates neuronal excitability in response to ischemia J Neurosci 25 48 11184 11193
-
(2005)
J Neurosci
, vol.25
, pp. 11184-11193
-
-
Misonou, H.1
Mohapatra, D.P.2
Menegola, M.3
Trimmer, J.S.4
-
56
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
6943
-
A Miyazawa Y Fujiyoshi N Unwin 2003 Structure and gating mechanism of the acetylcholine receptor pore Nature 23 6943 949 955
-
(2003)
Nature
, vol.23
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
57
-
-
0037184996
-
Structural basis of inward rectification: Cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution
-
M Nishida R MacKinnon 2002 Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution Cell 111 957 965
-
(2002)
Cell
, vol.111
, pp. 957-965
-
-
Nishida, M.1
MacKinnon, R.2
-
58
-
-
34748850615
-
Microfluidic integration of substantially round glass capillaries for lateral patch clamping on chip
-
10
-
WL Ong KC Tang A Agarwal R Nagarajan LW Luo L Yobas 2007 Microfluidic integration of substantially round glass capillaries for lateral patch clamping on chip Lab Chip 7 10 1357 1366
-
(2007)
Lab Chip
, vol.7
, pp. 1357-1366
-
-
Ong, W.L.1
Tang, K.C.2
Agarwal, A.3
Nagarajan, R.4
Luo, L.W.5
Yobas, L.6
-
59
-
-
0037470578
-
Voltage-gated K+ channel from mammalian brain: 3D structure at 18A of the complete (alpha)4(beta)4 complex
-
4
-
EV Orlova M Papakosta FP Booy M Van Heel JO Dolly 2003 Voltage-gated K+ channel from mammalian brain: 3D structure at 18A of the complete (alpha)4(beta)4 complex J Mol Biol 326 4 1005 1012
-
(2003)
J Mol Biol
, vol.326
, pp. 1005-1012
-
-
Orlova, E.V.1
Papakosta, M.2
Booy, F.P.3
Van Heel, M.4
Dolly, J.O.5
-
60
-
-
0037062485
-
Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome
-
12
-
N Ottschytsch A Raes D Van Hoorick DJ Snyders 2002 Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome Proc Natl Acad Sci USA 99 12 7986 7991
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7986-7991
-
-
Ottschytsch, N.1
Raes, A.2
Van Hoorick, D.3
Snyders, D.J.4
-
61
-
-
17644388821
-
Impaired KCNQ1-KCNE1 and phosphatidylinositol-4,5-bisphosphate interaction underlies the long QT syndrome
-
7
-
KH Park J Piron S Dahimene J Merot I Baro D Escande 2005 Impaired KCNQ1-KCNE1 and phosphatidylinositol-4,5-bisphosphate interaction underlies the long QT syndrome Circ Res 96 7 730 739
-
(2005)
Circ Res
, vol.96
, pp. 730-739
-
-
Park, K.H.1
Piron, J.2
Dahimene, S.3
Merot, J.4
Baro, I.5
Escande, D.6
-
64
-
-
33750999596
-
Antidystonic effects of Kv7 (KCNQ) channel openers in the dt sz mutant, an animal model of primary paroxysmal dystonia
-
6
-
A Richter SE Sander C Rundfeldt 2006 Antidystonic effects of Kv7 (KCNQ) channel openers in the dt sz mutant, an animal model of primary paroxysmal dystonia Br J Pharmacol 149 6 747 753
-
(2006)
Br J Pharmacol
, vol.149
, pp. 747-753
-
-
Richter, A.1
Sander, S.E.2
Rundfeldt, C.3
-
65
-
-
33747064405
-
Probing the regulation of M (Kv7) potassium channels in intact neurons with membrane-targeted peptides
-
30
-
J Robbins SJ Marsh DA Brown 2006 Probing the regulation of M (Kv7) potassium channels in intact neurons with membrane-targeted peptides J Neurosci 26 30 7950 7961
-
(2006)
J Neurosci
, vol.26
, pp. 7950-7961
-
-
Robbins, J.1
Marsh, S.J.2
Brown, D.A.3
-
66
-
-
23644450590
-
Genetics of acquired long QT syndrome
-
8
-
DM Roden PC Viswanathan 2005 Genetics of acquired long QT syndrome J Clin Invest 115 8 2025 2032
-
(2005)
J Clin Invest
, vol.115
, pp. 2025-2032
-
-
Roden, D.M.1
Viswanathan, P.C.2
-
67
-
-
0028566355
-
Heterotetramer formation and charybdotoxin sensitivity of two K+ channels cloned from smooth muscle
-
6 Pt 1
-
SN Russell KE Overturf B Horowitz 1994 Heterotetramer formation and charybdotoxin sensitivity of two K+ channels cloned from smooth muscle Am J Physiol 267 6 Pt 1 C1729 C1733
-
(1994)
Am J Physiol
, vol.267
-
-
Russell, S.N.1
Overturf, K.E.2
Horowitz, B.3
-
68
-
-
33644873454
-
TCDB: The Transporter Classification Database for membrane transport protein analyses and information
-
MH Saier Jr CV Tran RD Barabote 2006 TCDB: the Transporter Classification Database for membrane transport protein analyses and information Nucleic Acids Res 34 D181 D186
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Saier Jr., M.H.1
Tran, C.V.2
Barabote, R.D.3
-
69
-
-
0033082093
-
Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes
-
MC Sanguinetti QP Xu 1999 Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes J Physiol 514 667 675
-
(1999)
J Physiol
, vol.514
, pp. 667-675
-
-
Sanguinetti, M.C.1
Xu, Q.P.2
-
70
-
-
0034141999
-
A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly
-
3
-
N Schmitt M Schwarz A Peretz I Abitbol B Attali O Pongs 2000 A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly EMBO J 19 3 332 340
-
(2000)
EMBO J
, vol.19
, pp. 332-340
-
-
Schmitt, N.1
Schwarz, M.2
Peretz, A.3
Abitbol, I.4
Attali, B.5
Pongs, O.6
-
72
-
-
0029787483
-
Intersubunit interaction between amino- and carboxyl-terminal cysteine residues in tetrameric shaker K+ channels
-
37
-
CT Schulteis N Nagaya DM Papazian 1996 Intersubunit interaction between amino- and carboxyl-terminal cysteine residues in tetrameric shaker K+ channels Biochemistry 35 37 12133 12140
-
(1996)
Biochemistry
, vol.35
, pp. 12133-12140
-
-
Schulteis, C.T.1
Nagaya, N.2
Papazian, D.M.3
-
73
-
-
0037219281
-
A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly
-
1
-
M Schwake TJ Jentsch T Friedrich 2003 A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly EMBO Rep 4 1 76 81
-
(2003)
EMBO Rep
, vol.4
, pp. 76-81
-
-
Schwake, M.1
Jentsch, T.J.2
Friedrich, T.3
-
75
-
-
33646810883
-
Calmodulin is essential for cardiac IKS channel gating and assembly: Impaired function in long-QT mutations
-
8
-
L Shamgar L Ma N Schmitt Y Haitin A Peretz R Wiener 2006 Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations Circ Res 98 8 1055 1063
-
(2006)
Circ Res
, vol.98
, pp. 1055-1063
-
-
Shamgar, L.1
Ma, L.2
Schmitt, N.3
Haitin, Y.4
Peretz, A.5
Wiener, R.6
-
76
-
-
33750017572
-
A Kv4.2 truncation mutation in a patient with temporal lobe epilepsy
-
2
-
B Singh I Ogiwara M Kaneda N Tokonami E Mazaki K Baba K Matsuda Y Inoue K Yamakawa 2006 A Kv4.2 truncation mutation in a patient with temporal lobe epilepsy Neurobiol Dis 24 2 245 253
-
(2006)
Neurobiol Dis
, vol.24
, pp. 245-253
-
-
Singh, B.1
Ogiwara, I.2
Kaneda, M.3
Tokonami, N.4
Mazaki, E.5
Baba, K.6
Matsuda, K.7
Inoue, Y.8
Yamakawa, K.9
-
77
-
-
1942500485
-
Structure of cation channels, revealed by single particle electron microscopy
-
3
-
O Sokolova 2004 Structure of cation channels, revealed by single particle electron microscopy FEBS Lett 564 3 251 256
-
(2004)
FEBS Lett
, vol.564
, pp. 251-256
-
-
Sokolova, O.1
-
78
-
-
0035078574
-
Three-dimensional structure of a voltage-gated potassium channel at 2.5 nm resolution
-
3
-
O Sokolova L Kolmakova-Partensky N Grigorieff 2001 Three-dimensional structure of a voltage-gated potassium channel at 2.5 nm resolution Structure 9 3 215 220
-
(2001)
Structure
, vol.9
, pp. 215-220
-
-
Sokolova, O.1
Kolmakova-Partensky, L.2
Grigorieff, N.3
-
80
-
-
19344378895
-
Selective expression of HERG and Kv2 channels influences proliferation of uterine cancer cells
-
1
-
T Suzuki K Takimoto 2004 Selective expression of HERG and Kv2 channels influences proliferation of uterine cancer cells Int J Oncol 25 1 153 159
-
(2004)
Int J Oncol
, vol.25
, pp. 153-159
-
-
Suzuki, T.1
Takimoto, K.2
-
81
-
-
28444436590
-
Novel autoantibodies to a voltage-gated potassium channel Kv1.4 in a severe form of myasthenia gravis
-
1-2
-
S Suzuki T Satoh H Yasuoka Y Hamaguchi K Tanaka Y Kawakami N Suzuki M Kuwana 2005 Novel autoantibodies to a voltage-gated potassium channel Kv1.4 in a severe form of myasthenia gravis J Neuroimmunol 170 1-2 141 149
-
(2005)
J Neuroimmunol
, vol.170
, pp. 141-149
-
-
Suzuki, S.1
Satoh, T.2
Yasuoka, H.3
Hamaguchi, Y.4
Tanaka, K.5
Kawakami, Y.6
Suzuki, N.7
Kuwana, M.8
-
82
-
-
0037373464
-
[K(+)](o)-dependent change in conformation of the HERG1 long QT mutation N629D channel results in partial reversal of the in vitro disease phenotype
-
3
-
GQ Teng JP Lees-Miller Y Duan BT Li P Li HJ Duff 2003 [K(+)](o)-dependent change in conformation of the HERG1 long QT mutation N629D channel results in partial reversal of the in vitro disease phenotype Cardiovasc Res 57 3 642 650
-
(2003)
Cardiovasc Res
, vol.57
, pp. 642-650
-
-
Teng, G.Q.1
Lees-Miller, J.P.2
Duan, Y.3
Li, B.T.4
Li, P.5
Duff, H.J.6
-
83
-
-
0030859332
-
Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment
-
H Terlau SH Heinemann W Stuhmer O Pongs J Ludwig 1997 Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment J Physiol 502 537 543
-
(1997)
J Physiol
, vol.502
, pp. 537-543
-
-
Terlau, H.1
Heinemann, S.H.2
Stuhmer, W.3
Pongs, O.4
Ludwig, J.5
-
84
-
-
0025049953
-
Alteration and restoration of K+ channel function by deletions at the N- and C-termini
-
4
-
AM VanDongen GC Frech JA Drewe RH Joho AM Brown 1990 Alteration and restoration of K+ channel function by deletions at the N- and C-termini Neuron 5 4 433 443
-
(1990)
Neuron
, vol.5
, pp. 433-443
-
-
Vandongen, A.M.1
Frech, G.C.2
Drewe, J.A.3
Joho, R.H.4
Brown, A.M.5
-
85
-
-
0033917883
-
Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating
-
CG Viloria F Barros T Giraldez D Gomez-Varela P de la Pena 2000 Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating Biophys J 79 231 246
-
(2000)
Biophys J
, vol.79
, pp. 231-246
-
-
Viloria, C.G.1
Barros, F.2
Giraldez, T.3
Gomez-Varela, D.4
De La Pena, P.5
-
86
-
-
0031742141
-
Regulation of deactivation by an amino terminal domain in human ether-a-go-go-related gene potassium channels
-
J Wang MC Trudeau AM Zappia GA Robertson 1998 Regulation of deactivation by an amino terminal domain in human ether-a-go-go-related gene potassium channels J Gen Physiol 112 637 647
-
(1998)
J Gen Physiol
, vol.112
, pp. 637-647
-
-
Wang, J.1
Trudeau, M.C.2
Zappia, A.M.3
Robertson, G.A.4
-
87
-
-
33645421783
-
Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes
-
4
-
MF Waters NA Minassian G Stevanin KP Figeueroa JP Bannister D Nolte 2006 Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes Nat Genet 38 4 447 451
-
(2006)
Nat Genet
, vol.38
, pp. 447-451
-
-
Waters, M.F.1
Minassian, N.A.2
Stevanin, G.3
Figeueroa, K.P.4
Bannister, J.P.5
Nolte, D.6
-
88
-
-
0034084333
-
Neurological diseases caused by ion-channel mutations
-
3
-
F Weinreich TJ Jentsch 2000 Neurological diseases caused by ion-channel mutations Curr Opin Neurobiol 10 3 409 415
-
(2000)
Curr Opin Neurobiol
, vol.10
, pp. 409-415
-
-
Weinreich, F.1
Jentsch, T.J.2
-
89
-
-
0037107123
-
Calmodulin is an auxiliary subunit of KCNQ2/3 potassium channels
-
18
-
H Wen IB Levitan 2002 Calmodulin is an auxiliary subunit of KCNQ2/3 potassium channels J Neurosci 22 18 7991 8001
-
(2002)
J Neurosci
, vol.22
, pp. 7991-8001
-
-
Wen, H.1
Levitan, I.B.2
-
90
-
-
41949105973
-
The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction
-
9
-
R Wiener Y Haitin L Shamgar MC Fernández-Alonso A Martos Chomsky-Hecht G Rivas B Attali JA Hirsch 2008 The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction J Biol Chem 283 9 5815 5830
-
(2008)
J Biol Chem
, vol.283
, pp. 5815-5830
-
-
Wiener, R.1
Haitin, Y.2
Shamgar, L.3
Fernández-Alonso, M.C.4
Martos, A.5
Chomsky-Hecht6
Rivas, G.7
Attali, B.8
Hirsch, J.A.9
-
91
-
-
40649085627
-
Cone dystrophy with supernormal rod response is strictly associated with mutations in KCNV2
-
B Wissinger S Dangel H Jangle L Hansen 2008 Cone dystrophy with supernormal rod response is strictly associated with mutations in KCNV2 Invest Ophthalmol Vis Sci 49 751 757
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 751-757
-
-
Wissinger, B.1
Dangel, S.2
Jangle, H.3
Hansen, L.4
-
92
-
-
4344578299
-
The roles of intracellular regions in the activation of voltage-dependent potassium channels
-
D Wray 2004 The roles of intracellular regions in the activation of voltage-dependent potassium channels Eur J Biophys 33 194 200
-
(2004)
Eur J Biophys
, vol.33
, pp. 194-200
-
-
Wray, D.1
-
93
-
-
60549108756
-
Intracellular regions of potassium channels: Kv2.1 and heag
-
doi: 10.1007/s00249-008-0354-4
-
Wray D (2008) Intracellular regions of potassium channels: Kv2.1 and heag. Eur Biophys J, doi: 10.1007/s00249-008-0354-4
-
(2008)
Eur Biophys J
-
-
Wray, D.1
-
94
-
-
34648816542
-
Interaction of syntaxin 1A with the N-terminus of Kv4.2 modulates channel surface expression and gating
-
38
-
T Yamakawa S Saith Y Li X Gao HY Gaisano RG Tsushima 2007 Interaction of syntaxin 1A with the N-terminus of Kv4.2 modulates channel surface expression and gating Biochemistry 46 38 10942 10949
-
(2007)
Biochemistry
, vol.46
, pp. 10942-10949
-
-
Yamakawa, T.1
Saith, S.2
Li, Y.3
Gao, X.4
Gaisano, H.Y.5
Tsushima, R.G.6
-
95
-
-
0037026489
-
The voltage-gated potassium channels and their relatives
-
6902
-
G Yellen 2002 The voltage-gated potassium channels and their relatives Nature 419 6902 35 42
-
(2002)
Nature
, vol.419
, pp. 35-42
-
-
Yellen, G.1
-
96
-
-
0037047394
-
The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels
-
32
-
E Yus-Najera I Santana-Castro A Villarroel 2002 The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels J Biol Chem 277 32 28545 28553
-
(2002)
J Biol Chem
, vol.277
, pp. 28545-28553
-
-
Yus-Najera, E.1
Santana-Castro, I.2
Villarroel, A.3
-
98
-
-
0347154149
-
An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1
-
7
-
N Zerangue YN Jan LY Jan 2000 An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1 Proc Natl Acad Sci USA 97 7 3591 3595
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3591-3595
-
-
Zerangue, N.1
Jan, Y.N.2
Jan, L.Y.3
|