Impaired KCNQ1-KCNE1 and phosphatidylinositol-4,5-bisphosphate interaction underlies the long QT syndrome

Circulation Research

Volumn 96, Issue 7, 2005, Pages 730-739

  Park, Kyu Ho ^a,b   Piron, Julien ^a   Dahimene, Shehrazade ^a   Mérot, Jean ^a   Baró, Isabelle ^a   Escande, Denis ^a   Loussouarn, Gildas ^a  

^a L INSTITUT DU THORAX   (France)

^b INST DE BIOLOGIE PHYSICO CHIMIQUE   (France)

Author keywords

KCNE1; KCNQ1; Long QT syndrome; Phosphatidylinositol 4,5 bisphosphate

Indexed keywords

AMMONIUM DERIVATIVE; METHANETHIOSULFONATE ETHYLAMMONIUM; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POTASSIUM CHANNEL KCNQ1; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; DISSOCIATION CONSTANT; EQUILIBRIUM CONSTANT; GENE MUTATION; LONG QT SYNDROME; MEMBRANE BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; POTASSIUM CHANNEL KCNE1; PRIORITY JOURNAL; QT PROLONGATION; REGULATORY MECHANISM; WHOLE CELL; WILD TYPE;

EID: 17644388821     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000161451.04649.a8     Document Type: Article

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