The voltage-gated potassium channels and their relatives

Nature

Volumn 419, Issue 6902, 2002, Pages 35-42

  Yellen, Gary ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IONS; MATERIALS; POTASSIUM; PROTEINS;

ARCHITECTURAL MODULES;

ELECTRIC POTENTIAL;

CALCIUM ION; ION CHANNEL; POTASSIUM CHANNEL; POTASSIUM ION; SODIUM ION; VOLTAGE GATED POTASSIUM CHANNEL;

PROTEIN;

BINDING SITE; MEMBRANE CHANNEL; MEMBRANE CONDUCTANCE; MEMBRANE PERMEABILITY; NERVE CELL; PRIORITY JOURNAL; REVIEW; SENSOR;

ANIMALS; CALCIUM; ELECTRIC CONDUCTIVITY; ION CHANNEL GATING; LIGANDS; MODELS, MOLECULAR; POTASSIUM; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; SODIUM; SUBSTRATE SPECIFICITY;

EID: 0037026489     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature00978     Document Type: Review

References (81)

1. A quantitative description of membrane current and its application to conduction and excitation in nerve
2. Conduction and selectivity in potassium channels
3. The structure of the potassium channel: Molecular basis of potassium conduction and selectivity
4. + channel-Fab complex at 2.0 Å resolution
5. + selectivity filter
6. The open pore conformation of potassium channels
7. + channel: Electrostatic stabilization of monovalent cations
8. X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity
9. Ionic pores, gates, and gating currents
10. The potassium permeability of a giant nerve fibre
11. Potassium channels as multi-ion single-file pores
12. + channel
13. + channel
14. + channel
15. + channel and its structural implications
16. + channel can be trapped in the open state by an intersubunit metal bridge
17. + channel activation gating
18. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axon
19. + channels: Evidence for a trap door mechanism of activation gating
20. Biophysical and molecular mechanisms of Shaker potassium channel inactivation
21. + channels altered by presence of β-subunit
22. + channels by a peptide derived from ShB
23. Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides
24. Energetics of Shaker K channels block by inactivation peptides
25. + channels
26. + channel behaves like an open-channel blocker
27. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors
28. K(A) channels by cysteine oxidation
29. NIP domain prevents N-type inactivation in voltage-gated potassium channels
30. + channel beta subunit
31. + channel
32. Three-dimensional structure of a voltage-gated potassium channel at 2.5 nm resolution
33. + channels: Effects of alterations in the carboxy terminal region
34. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels
35. + channel allows inactivation to be modulated by metal binding
36. + channel during gating
37. + channel
38. +]: A tale of two inactivation mechanisms
39. Contribution of the selectivity filter to inactivation in potassium channels
40. + channel suggest a subunit basis for ion permeation and gating
41. Selectivity changes during activation of mutant Shaker potassium channels
42. Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels
43. Voltage-controlled gating at the intracellular entrance to a hyperpolarization-activated cation channel
44. Rotational movement during cyclic nucleotide-gated channel opening
45. + channel and demonstration of its presence in the human BK channel
46. Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers
47. Crystal structure and mechanism of a calcium-gated potassium channel
48. Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 Å resolution
49. Functional characterization of a potassium-selective prokaryaric glutamate receptor
50. Mechanism of glutamate receptor desensitization
51. Mechanism of calcium gating in small-conductance calcium-activated potassium channels
52. 2+/calmodulin
53. Voltage gating of ion channels
54. Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence
55. + channel
56. + channel
57. + channel
58. Electrostatics and the gating pore of Shaker potassium channels
59. Molecular basis of charge movement in voltage-gated sodium channels
60. + channel S4
61. + channels in open, closed, and inactivated conformations
62. + channel
63. + channel
64. + channel
65. Molecular model of the action potential sodium channel
66. Voltage-dependent gating of sodium channels: Correlating structure and function
67. Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel
68. Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy
69. S4 charges move close to residues in the pore domain during activation in a K channel
70. + channels
71. + channels
72. A prokaryotic voltage-gated sodium channel
73. Crystal structure of the tetramerization domain of the Shaker potassium channel
74. + channels
75. + channel subunit proteins
76. Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain
77. Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
78. + channels: An additional transmembrane region at the N terminus
79. Crystal structure and functional analysis of the HERG potassium channel N terminus: A eukaryotic PAS domain
80. + channel. Identification of the site of incorporation and implications for channel topology
81. Location and orientation of minK within the I(Ks) potassium channel complex