PIP2 activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents

Neuron

Volumn 37, Issue 6, 2003, Pages 963-975

  Zhang, Hailin ^a,b   Craciun, Liviu C ^a   Mirshahi, Tooraj ^a   Rohács, Tibor ^a   Lopes, Coeli M B ^a   Jin, Taihao ^a   Logothetis, Diomedes E ^a  

^a NEW YORK UNIVERSITY   (United States)

^b HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; MUSCARINIC AGENT; PHOSPHOLIPID; RECEPTOR; TRIPHOSPHOINOSITIDE; WORTMANNIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL SURFACE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIFFUSION; HYDROLYSIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0037468826     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(03)00125-9     Document Type: Article

References (63)

1. Adams P.R., Brown D.A. Luteinizing hormone-releasing factor and muscarinic agonists act on the same voltage-sensitive K+-current inbullfrog sympathetic neurones. Br. J. Pharmacol. 68:1980;353-355.
2. Adams P.R., Brown D.A., Jones S.W. Substance P inhibits the M-current in bullfrog sympathetic neurones. Br. J. Pharmacol. 79:1983;330-333.
3. Aharonovitz O., Zaun H.C., Balla T., York J.D., Orlowski J., Grinstein S. Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. J. Cell Biol. 150:2000;213-224.
4. 2+ current and M current in rat sympathetic neurons. Proc. Natl. Acad. Sci. USA. 88:1991;652-656.
5. Biervert C., Schroeder B.C., Kubisch C., Berkovic S.F., Propping P., Jentsch T.J., Steinlein O.K. A potassium channel mutation in neonatal human epilepsy. Science. 279:1998;403-406.
6. Bosma M.M., Hille B. Protein kinase C is not necessary for peptide-induced suppression of M current or for desensitization of the peptide receptors. Proc. Natl. Acad. Sci. USA. 86:1989;2943-2947.
7. Brown B.S., Yu S.P. Modulation and genetic identification of the M channel. Prog. Biophys. Mol. Biol. 73:2000;135-166.
8. Brown D.A., Adams P.R. Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone. Nature. 283:1980;673-676.
9. 2-mediated inhibition. Nature. 411:2001;957-962.
10. Cooper E.C., Aldape K.D., Abosch A., Barbaro N.M., Berger M.S., Peacock W.S., Jan Y.N., Jan L.Y. Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy. Proc. Natl. Acad. Sci. USA. 97:2000;4914-4919.
11. Cruzblanca H., Koh D.S., Hille B. Bradykinin inhibits M current via phospholipase C and Ca2+ release from IP3-sensitive Ca2+ stores in rat sympathetic neurons. Proc. Natl. Acad. Sci. USA. 95:1998;7151-7156.
12. 3. complex roles at the cell surface Cell. 100:2000;603-606.
13. 2+ mobilisation in rat sympathetic neurones, but this signalling pathway does not mediate M-current inhibition. J. Physiol. 520:1999;101-111.
14. Estacion M., Sinkins W.G., Schilling W.P. Regulation of Drosophila transient receptor potential-like (TrpL) channels by phospholipase C-dependent mechanisms. J. Physiol. 530:2001;1-19.
15. Fan Z., Makielski J.C. Anionic phospholipids activate ATP-sensitive potassium channels. J. Biol. Chem. 272:1997;5388-5395.
16. + currents. J. Neurosci. 18:1998;5170-5179.
17. Hadley J.K., Noda M., Selyanko A.A., Wood I.C., Abogadie F.C., Brown D.A. Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels. Br. J. Pharmacol. 129:2000;413-415.
18. Hamill O.P., Marty A., Neher E., Sakmann B., Sigworth F.J. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391:1981;85-100.
19. + currents in rat ventricular myocytes. Circ. Res. 91:2002;232-239.
20. Hawrot E., Patterson P.H. Long-term culture of dissociated sympathetic neurons. Methods Enzymol. 58:1979;574-584.
21. Higashida H., Brown D.A. Two polyphosphatidylinositide metabolites control two K+ currents in a neuronal cell. Nature. 323:1986;333-335.
22. Hilgemann D.W. Cytoplasmic ATP-dependent regulation of ion transporters and channels. mechanisms and messengers Annu. Rev. Physiol. 59:1997;193-220.
23. 2. Science. 273:1996;956-959.
24. 2 with ion channels and transporters. Sci. STKE. 111:2001;RE19.
25. 2 and its stabilization by Gbetagamma. Nature. 391:1998;803-806.
26. Ikeda S., Kammermeier P. M current mystery messenger revealed? Neuron. 35:2002;411-412.
27. Jentsch T.J. Neuronal KCNQ potassium channels. physiology and role in disease Nat. Rev. Neurosci. 1:2000;21-30.
28. +-current desensitization. Nat. Cell Biol. 2:2000;507-514.
29. Kubisch C., Schroeder B.C., Friedrich T., Lutjohann B., El Amraoui A., Marlin S., Petit C., Jentsch T.J. KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness. Cell. 96:1999;437-446.
30. Lerche C., Scherer C.R., Seebohm G., Derst C., Wei A.D., Busch A.E., Steinmeyer K. Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity. J. Biol. Chem. 275:2000;22395-22400.
31. + channel in heart. Nature. 325:1987;321-326.
32. Logothetis D.E., Movahedi S., Satler C., Lindpaintner K., Nadal-Ginard B. Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge. Neuron. 8:1992;531-540.
33. 2 and Kir channels underlie channelopathies. Neuron. 34:2002;933-944.
34. Lupu V.D., Kaznacheyeva E., Krishna U.M., Falck J.R., Bezprozvanny I. Functional coupling of phosphatidylinositol 4,5-bisphosphate to inositol 1,4,5-trisphosphate receptor. J. Biol. Chem. 273:1998;14067-14070.
35. Ma H.P., Saxena S., Warnock D.G. Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC). J. Biol. Chem. 277:2002;7641-7644.
36. Marrion N.V. Selective reduction of one mode of M-channel gating by muscarine in sympathetic neurons. Neuron. 11:1993;77-84.
37. Marrion N.V. Control of M-current. Annu. Rev. Physiol. 59:1997;483-504.
38. Nakanishi S., Catt K.J., Balla T. A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids. Proc. Natl. Acad. Sci. USA. 92:1995;5317-5321.
39. 2 metabolism in guinea pig ventricular cells. Am. J. Physiol. Heart Circ. Physiol. 282:2002;H757-H765.
40. 2+ transients, but these events do not explain M-current suppression. Neuron. 1:1988;477-484.
41. + channels for phosphoinositides. J. Biol. Chem. 274:1999;36065-36072.
42. 2 regulation of potassium channels. G Protein Pathways. 2002;Academic Press, Inc, Methods in Enzymology, J. Hildebrandt and R. Iyengar, eds. (San Diego, CA. a 71-92.pp.
43. Rohács T., Lopes C.M.B., Ramdya P., Jin T., Logothetis D.E. Specificity of activation by phosphoinositides determines lipid regulation of Kir channels. Proc. Natl. Acad. Sci. USA. 100:2002;745-750. b.
44. 2 hydrolysis. Nat. Cell Biol. 4:2002;329-336.
45. + channels causes epilepsy. Nature. 396:1998;687-690.
46. Selyanko A.A., Brown D.A. Effects of membrane potential and muscarine on potassium M-channel kinetics in rat sympathetic neurones. (1993). J. Physiol. 472:1993;711-724.
47. Selyanko A.A., Stansfeld C.E., Brown D.A. Closure of potassium M-channels by muscarinic acetylcholine-receptor stimulants requires a diffusible messenger. Proc. R. Soc. Lond. B Biol. Sci. 250:1992;119-125.
48. Selyanko A.A., Hadley J.K., Wood I.C., Abogadie F.C., Jentsch T.J., Brown D.A. Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors. J. Physiol. 522:2000;349-355.
49. Selyanko A.A., Hadley J.K., Brown D.A. Properties of single M-type KCNQ2/KCNQ3 potassium channels expressed in mammalian cells. J. Physiol. 534:2001;15-24.
50. Shapiro M.S., Roche J.P., Kaftan E.J., Cruzblanca H., Mackie K., Hille B. Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current. J. Neurosci. 20:2000;1710-1721.
51. +-channel by the muscarinic receptor in rabbit atrial cells. Pflugers Arch. 400:1984;424-431.
52. 2 concentration monitored in living cells. Curr. Biol. 8:1998;343-346.
53. Suh B., Hille B. Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron. 35:2002;507-520.
54. + ions depends on the presence of phosphatidylinositol phosphates. Proc. Natl. Acad. Sci. USA. 95:1998;1307-1312.
55. Tokimasa T., Ito M., Simmons M.A., Schneider C.R., Tanaka T., Nakano T., Akasu T. Inhibition by wortmannin of M-current in bullfrog sympathetic neurones. Br. J. Pharmacol. 114:1995;489-495.
56. Varnai P., Balla T. Visualization of phosphoinositides that bind pleckstrin homology domains. calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositollabeled phosphoinositide pools J. Cell Biol. 143:1998;501-510.
57. ACh channel, using functional homomeric mutants. J. Biol. Chem. 272:1997;31553-31560.
58. Wang H.S., Pan Z., Shi W., Brown B.S., Wymore R.S., Cohen I.S., Dixon J.E., McKinnon D. KCNQ2 and KCNQ3 potassium channel subunits. molecular correlates of the M-channel Science. 282:1998;1890-1893.
59. Wang Q., Curran M.E., Splawski I., Burn T.C., Millholland J.M., VanRaay T.J., Shen J., Timothy K.W., Vincent G.M., de Jager T.et al. Positional cloning of a novel potassium channel gene. KVLQT1 mutations cause cardiac arrhythmias Nat. Genet. 12:1996;17-23.
60. Womack K.B., Gordon S.E., He F., Wensel T.G., Lu C.C., Hilgemann D.W. Do phosphatidylinositides modulate vertebrate phototransduction? J. Neurosci. 20:2000;2792-2799.
61. Xie L.H., Horie M., Takano M. Phospholipase C-linked receptors regulate the ATP-sensitive potassium channel by means of phosphatidylinositol 4,5-bisphosphate metabolism. Proc. Natl. Acad. Sci. USA. 96:1999;15292-15297.
62. 2) stimulates epithelial sodium channel activity in A6 cells. J. Biol. Chem. 277:2002;11965-11969.
63. + channels by distinct PtdIns(4,5)P2 interactions. Nat. Cell Biol. 1:1999;183-188.