Trapping of organic blockers by closing of voltage-dependent K+ channels: Evidence for a trap door mechanism of activation gating

Journal of General Physiology

Volumn 109, Issue 5, 1997, Pages 527-535

  Holmgren, Miguel ^a   Smith, Paula L ^a   Yellen, Gary ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

ion channel gating; open channel blockade; potassium channels; tetraethylammonium compounds; use dependent blockade

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; QUATERNARY AMMONIUM DERIVATIVE; TETRYLAMMONIUM;

ARTICLE; CHANNEL GATING; ENERGY TRANSFER; HUMAN; HUMAN CELL; KINETICS; MEMBRANE POTENTIAL; POINT MUTATION;

ANIMALS; CELL LINE; ELECTROPHYSIOLOGY; ENERGY METABOLISM; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MICE; POTASSIUM CHANNELS; RECOMBINANT PROTEINS; TETRAETHYLAMMONIUM COMPOUNDS;

EID: 0030956162     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.109.5.527     Document Type: Article

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