hERG gating microdomains defi ned by s6 mutagenesis and molecular modeling

Journal of General Physiology

Volumn 132, Issue 5, 2008, Pages 507-520

  Sarah, L Wynia Smith ^a   Anne, Lynn Gillian Daniel ^a,b   Satyshur, Kenneth A ^a   Robertson, Gail A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYSTEINE; POTASSIUM CHANNEL HERG; S6 KINASE;

ARTICLE; CELL MEMBRANE CONDUCTANCE; CHANNEL GATING; CRYSTAL STRUCTURE; DRUG BINDING; MOLECULAR MODEL; MUTAGENESIS; NONHUMAN; OOCYTE; PROTEIN DOMAIN; RNA SYNTHESIS; STEADY STATE; XENOPUS LAEVIS; AMINO ACID SUBSTITUTION; ANIMAL; CELL MEMBRANE POTENTIAL; CHEMICAL STRUCTURE; CHEMISTRY; ENERGY TRANSFER; ENZYME ACTIVE SITE; GENETICS; HUMAN; HYDROPHOBICITY; KINETICS; METABOLISM; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

AMINO ACID SUBSTITUTION; ANIMALS; CATALYTIC DOMAIN; ENERGY TRANSFER; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; HYDROPHOBICITY; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PROTEIN INTERACTION DOMAINS AND MOTIFS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 59449096598     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.200810083     Document Type: Article

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