Demonstration of physical proximity between the n terminus and the S4-S5 linker of the human ether-à-go-go-related gene (hERG) potassium channel

Journal of Biological Chemistry

Volumn 286, Issue 21, 2011, Pages 19065-19075

  De La Peña, Pilar ^a   Alonso Ron, Carlos ^a,b   Machín, Angeles ^a   Fernández Trillo, Jorge ^a   Carretero, Luis ^a   Domínguez, Pedro ^a   Barros, Francisco ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b Fundacion de Investigacion Oftalmologica   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELL TYPES; CHANNEL GATES; CHANNEL GATING; CLOSE PROXIMITY; CYTOPLASMIC DOMAINS; DISULFIDE BOND FORMATION; DISULFIDE BONDS; DITHIOTHREITOL; ELECTRICAL BEHAVIORS; ESSENTIAL COMPONENT; INTERACTION SITE; MOLECULAR BASIS; OXIDIZING AGENTS; OXIDIZING CONDITIONS; PHYSICAL INTERACTIONS; PHYSICAL PROXIMITY; POTASSIUM CHANNELS; REPOLARIZATION; STATE-DEPENDENT;

COVALENT BONDS; ETHERS; GENES; MACHINERY; ORGANIC COMPOUNDS; POTASSIUM;

AMINO ACIDS;

CYSTEINE DERIVATIVE; DITHIOTHREITOL; OXIDIZING AGENT; POTASSIUM CHANNEL HERG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DNA MODIFICATION; GENE; GENE FUNCTION; GENE SEQUENCE; HERG GENE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN LOCALIZATION; XENOPUS LAEVIS;

AMINO ACID SUBSTITUTION; ANIMALS; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; ION CHANNEL GATING; MUTATION, MISSENSE; PROTEIN STRUCTURE, TERTIARY; XENOPUS LAEVIS;

EID: 79956326492     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.238899     Document Type: Article

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