Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: Implications in the pathogenesis of age-related macular degeneration

Molecular Aspects of Medicine

Volumn 33, Issue 4, 2012, Pages 446-466

  Shang, Fu ^a   Taylor, Allen ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Aging; Inflammation; Macula; Oxidative stress; Protein quality control; Proteolysis; Retina degeneration; Signal transduction

Indexed keywords

ANGIOGENIC FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEASOME; UBIQUITIN;

AGING; CELL CYCLE REGULATION; HUMAN; LYSOSOME MEMBRANE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; MOLECULAR RECOGNITION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN UNFOLDING; RETINA DEVELOPMENT; RETINA MACULA AGE RELATED DEGENERATION; REVIEW; SIGNAL TRANSDUCTION; UBIQUITIN PROTEASOME PATHWAY; UBIQUITINATION; VISUAL ACUITY; VISUAL FEEDBACK;

ANIMALS; GLYCOPROTEINS; HUMANS; MACULAR DEGENERATION; NEOVASCULARIZATION, PHYSIOLOGIC; NF-KAPPA B; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; RETINA; SIGNAL TRANSDUCTION; UBIQUITIN;

EID: 84863723478     PISSN: 00982997     EISSN: 18729452     Source Type: Journal    
DOI: 10.1016/j.mam.2012.04.001     Document Type: Review

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