Inhibition of NF-κB cellular function via specific targeting of the IκB-ubiquitin ligase

EMBO Journal

Volumn 16, Issue 21, 1997, Pages 6486-6494

  Yaron, Avraham ^a   Gonen, Hedva ^b   Alkalay, Irit ^a   Hatzubai, Ada ^a   Jung, Steffen ^a   Beyth, Shaul ^c   Mercurio, Frank ^d   Manning, Anthony M ^d   Ciechanover, Aaron ^b   Ben Neriah, Yinon ^a  

^a HEBREW UNIVERSITY   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^d Signal Pharmaceuticals   (United States)

Author keywords

Degradation; I B phosphorylation; NF B; Ubiquitin; Ubiquitin ligase motif

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOPEPTIDE; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL FUNCTION; CELL STIMULATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MICROINJECTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; CELL NUCLEUS; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; CYTOPLASM; E-SELECTIN; ENDOTHELIUM, VASCULAR; HELA CELLS; HUMANS; JURKAT CELLS; LIGASES; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; NF-KAPPA B; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELB; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS; UMBILICAL VEINS;

EID: 0030731146     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.21.6486     Document Type: Article

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