-
1
-
-
0031030057
-
Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum
-
Akopian T.N., Kisselev A.F., Goldberg A.L. Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum. J. Biol. Chem. 272:1997;1791-1798
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1791-1798
-
-
Akopian, T.N.1
Kisselev, A.F.2
Goldberg, A.L.3
-
2
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
Arrasate M., Mitra S., Schweitzer E.S., Segal M.R., Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature. 431:2004;805-810
-
(2004)
Nature
, vol.431
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
3
-
-
0009851133
-
Molecular cloning of a novel ubiquitin-specific protease, UBP41, with isopeptidase activity in chick skeletal muscle
-
Baek S.H., Choi K.S., Yoo Y.J., Cho J.M., Baker R.T., Tanaka K., Chung C.H. Molecular cloning of a novel ubiquitin-specific protease, UBP41, with isopeptidase activity in chick skeletal muscle. J. Biol. Chem. 272:1997;25560-25565
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25560-25565
-
-
Baek, S.H.1
Choi, K.S.2
Yoo, Y.J.3
Cho, J.M.4
Baker, R.T.5
Tanaka, K.6
Chung, C.H.7
-
4
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence N., Sampat R., Kopito R.R. Impairment of the ubiquitin-proteasome system by protein aggregation. Science. 292:2001;1552-1555
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.1
Sampat, R.2
Kopito, R.R.3
-
5
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini M., Giannoni E., Chiti F., Baroni F., Formigli L., Zurdo J., Taddei N., Ramponi G., Dobson C.M., Stefani M. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature. 416:2002;507-511
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
6
-
-
0035878111
-
MAD2B is an inhibitor of the anaphase-promoting complex
-
Chen J., Fang G. MAD2B is an inhibitor of the anaphase-promoting complex. Genes Dev. 15:2001;1765-1770
-
(2001)
Genes Dev.
, vol.15
, pp. 1765-1770
-
-
Chen, J.1
Fang, G.2
-
7
-
-
0035084096
-
Solubilization and disaggregation of polyglutamine peptides
-
Chen S., Wetzel R. Solubilization and disaggregation of polyglutamine peptides. Protein Sci. 10:2001;887-891
-
(2001)
Protein Sci.
, vol.10
, pp. 887-891
-
-
Chen, S.1
Wetzel, R.2
-
8
-
-
0035800572
-
Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity
-
Chen S., Berthelier V., Yang W., Wetzel R. Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity. J. Mol. Biol. 311:2001;173-182
-
(2001)
J. Mol. Biol.
, vol.311
, pp. 173-182
-
-
Chen, S.1
Berthelier, V.2
Yang, W.3
Wetzel, R.4
-
9
-
-
0035291218
-
Regulation of cellular polyamines by antizyme
-
Coffino P. Regulation of cellular polyamines by antizyme. Nat. Rev. Mol. Cell Biol. 2:2001;188-194
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 188-194
-
-
Coffino, P.1
-
10
-
-
0031838352
-
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
-
Cummings C.J., Mancini M.A., Antalffy B., DeFranco D.B., Orr H.T., Zoghbi H.Y. Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat. Genet. 19:1998;148-154
-
(1998)
Nat. Genet.
, vol.19
, pp. 148-154
-
-
Cummings, C.J.1
Mancini, M.A.2
Antalffy, B.3
Defranco, D.B.4
Orr, H.T.5
Zoghbi, H.Y.6
-
12
-
-
0033391428
-
Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice
-
b
-
Cummings C.J., Reinstein E., Sun Y., Antalffy B., Jiang Y., Ciechanover A., Orr H.T., Beaudet A.L., Zoghbi H.Y. Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice. Neuron. 24:1999;879-892. b
-
(1999)
Neuron
, vol.24
, pp. 879-892
-
-
Cummings, C.J.1
Reinstein, E.2
Sun, Y.3
Antalffy, B.4
Jiang, Y.5
Ciechanover, A.6
Orr, H.T.7
Beaudet, A.L.8
Zoghbi, H.Y.9
-
13
-
-
0042808497
-
Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates
-
Donaldson K.M., Li W., Ching K.A., Batalov S., Tsai C.C., Joazeiro C.A. Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates. Proc. Natl. Acad. Sci. USA. 100:2003;8892-8897
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8892-8897
-
-
Donaldson, K.M.1
Li, W.2
Ching, K.A.3
Batalov, S.4
Tsai, C.C.5
Joazeiro, C.A.6
-
14
-
-
0034597833
-
Identification of genes that modify ataxin-1-induced neurodegeneration
-
Fernandez-Funez P., Nino-Rosales M.L., de Gouyon B., She W.C., Luchak J.M., Martinez P., Turiegano E., Benito J., Capovilla M., Skinner P.J., et al. Identification of genes that modify ataxin-1-induced neurodegeneration. Nature. 408:2000;101-106
-
(2000)
Nature
, vol.408
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.L.2
De Gouyon, B.3
She, W.C.4
Luchak, J.M.5
Martinez, P.6
Turiegano, E.7
Benito, J.8
Capovilla, M.9
Skinner, P.J.10
-
15
-
-
0031932169
-
Protein aggregation: Folding aggregates, inclusion bodies and amyloid
-
Fink A.L. Protein aggregation. folding aggregates, inclusion bodies and amyloid Fold. Des. 3:1998;R9-R23
-
(1998)
Fold. Des.
, vol.3
-
-
Fink, A.L.1
-
16
-
-
0029130169
-
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
-
Fischer U., Huber J., Boelens W.C., Mattaj I.W., Lührmann R. The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell. 82:1995;475-483
-
(1995)
Cell
, vol.82
, pp. 475-483
-
-
Fischer, U.1
Huber, J.2
Boelens, W.C.3
Mattaj, I.W.4
Lührmann, R.5
-
17
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
Gunawardena S., Her L.S., Brusch R.G., Laymon R.A., Niesman I.R., Gordesky-Gold B., Sintasath L., Bonini N.M., Goldstein L.S. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron. 40:2003;25-40
-
(2003)
Neuron
, vol.40
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
Sintasath, L.7
Bonini, N.M.8
Goldstein, L.S.9
-
18
-
-
0032946228
-
In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease
-
Hackam A.S., Singaraja R., Zhang T., Gan L., Hayden M.R. In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease. Hum. Mol. Genet. 8:1999;25-33
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 25-33
-
-
Hackam, A.S.1
Singaraja, R.2
Zhang, T.3
Gan, L.4
Hayden, M.R.5
-
19
-
-
0347298778
-
Spongiform degeneration in mahoganoid mutant mice
-
He L., Lu X.Y., Jolly A.F., Eldridge A.G., Watson S.J., Jackson P.K., Barsh G.S., Gunn T.M. Spongiform degeneration in mahoganoid mutant mice. Science. 299:2003;710-712
-
(2003)
Science
, vol.299
, pp. 710-712
-
-
He, L.1
Lu, X.Y.2
Jolly, A.F.3
Eldridge, A.G.4
Watson, S.J.5
Jackson, P.K.6
Barsh, G.S.7
Gunn, T.M.8
-
21
-
-
9144223729
-
Inefficient degradation of truncated polyglutamine proteins by the proteasome
-
Holmberg C.I., Staniszewski K.E., Mensah K.N., Matouschek A., Morimoto R.I. Inefficient degradation of truncated polyglutamine proteins by the proteasome. EMBO J. 23:2004;4307-4318
-
(2004)
EMBO J.
, vol.23
, pp. 4307-4318
-
-
Holmberg, C.I.1
Staniszewski, K.E.2
Mensah, K.N.3
Matouschek, A.4
Morimoto, R.I.5
-
22
-
-
0037072934
-
A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system
-
Illing M.E., Rajan R.S., Bence N.F., Kopito R.R. A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system. J. Biol. Chem. 277:2002;34150-34160
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34150-34160
-
-
Illing, M.E.1
Rajan, R.S.2
Bence, N.F.3
Kopito, R.R.4
-
23
-
-
0035336658
-
Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release
-
Jana N.R., Zemskov E.A., Wang G., Nukina N. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release. Hum. Mol. Genet. 10:2001;1049-1059
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1049-1059
-
-
Jana, N.R.1
Zemskov, E.A.2
Wang, G.3
Nukina, N.4
-
24
-
-
0033749379
-
Formation of high molecular weight complexes of mutant cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
-
Johnston J.A., Dalton M.J., Gurney M.E., Kopito R.R. Formation of high molecular weight complexes of mutant cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA. 97:2000;12571-12576
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12571-12576
-
-
Johnston, J.A.1
Dalton, M.J.2
Gurney, M.E.3
Kopito, R.R.4
-
25
-
-
0021269089
-
Sequence requirements for nuclear location of simian virus 40 large-T antigen
-
Kalderon D., Richardson W.D., Markham A.F., Smith A.E. Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature. 311:1984;33-38
-
(1984)
Nature
, vol.311
, pp. 33-38
-
-
Kalderon, D.1
Richardson, W.D.2
Markham, A.F.3
Smith, A.E.4
-
26
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
Kawaguchi Y., Kovacs J.J., McLaurin A., Vance J.M., Ito A., Yao T.P. The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell. 115:2003;727-738
-
(2003)
Cell
, vol.115
, pp. 727-738
-
-
Kawaguchi, Y.1
Kovacs, J.J.2
McLaurin, A.3
Vance, J.M.4
Ito, A.5
Yao, T.P.6
-
27
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R., Head E., Thompson J.L., McIntire T.M., Milton S.C., Cotman C.W., Glabe C.G. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science. 300:2003;486-489
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
28
-
-
0033613212
-
Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells
-
Kazantsev A., Preisinger E., Dranovsky A., Goldgaber D., Housman D. Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells. Proc. Natl. Acad. Sci. USA. 96:1999;11404-11409
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 11404-11409
-
-
Kazantsev, A.1
Preisinger, E.2
Dranovsky, A.3
Goldgaber, D.4
Housman, D.5
-
29
-
-
0036797242
-
Polyglutamine protein aggregates are dynamic
-
Kim S., Nollen E.A., Kitagawa K., Bindokas V.P., Morimoto R.I. Polyglutamine protein aggregates are dynamic. Nat. Cell Biol. 4:2002;826-831
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 826-831
-
-
Kim, S.1
Nollen, E.A.2
Kitagawa, K.3
Bindokas, V.P.4
Morimoto, R.I.5
-
30
-
-
0032475941
-
Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
-
Klement I.A., Skinner P.J., Kaytor M.D., Yi H., Hersch S.M., Clark H.B., Zoghbi H.Y., Orr H.T. Ataxin-1 nuclear localization and aggregation. role in polyglutamine-induced disease in SCA1 transgenic mice Cell. 95:1998;41-53
-
(1998)
Cell
, vol.95
, pp. 41-53
-
-
Klement, I.A.1
Skinner, P.J.2
Kaytor, M.D.3
Yi, H.4
Hersch, S.M.5
Clark, H.B.6
Zoghbi, H.Y.7
Orr, H.T.8
-
31
-
-
0033621165
-
Amyloid diseases: Abnormal protein aggregation in neurodegeneration
-
Koo E.H., Lansbury P.T. Jr., Kelly J.W. Amyloid diseases. abnormal protein aggregation in neurodegeneration Proc. Natl. Acad. Sci. USA. 96:1999;9989-9990
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9989-9990
-
-
Koo, E.H.1
Lansbury Jr., P.T.2
Kelly, J.W.3
-
32
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito R.R. Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol. 10:2000;524-530
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
33
-
-
0037130174
-
Neurodegenerative disease: Amyloid pores from pathogenic mutations
-
Lashuel H.A., Hartley D., Petre B.M., Walz T., Lansbury P.T. Jr. Neurodegenerative disease. amyloid pores from pathogenic mutations Nature. 418:2002;291
-
(2002)
Nature
, vol.418
, pp. 291
-
-
Lashuel, H.A.1
Hartley, D.2
Petre, B.M.3
Walz, T.4
Lansbury Jr., P.T.5
-
34
-
-
0034895295
-
Parkin and Parkinson's disease
-
Mizuno Y., Hattori N., Mori H., Suzuki T., Tanaka K. Parkin and Parkinson's disease. Curr. Opin. Neurol. 14:2001;477-482
-
(2001)
Curr. Opin. Neurol.
, vol.14
, pp. 477-482
-
-
Mizuno, Y.1
Hattori, N.2
Mori, H.3
Suzuki, T.4
Tanaka, K.5
-
35
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
Nucifora F.C. Jr., Sasaki M., Peters M.F., Huang H., Cooper J.K., Yamada M., Takahashi H., Tsuji S., Troncoso J., Dawson V.L., et al. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science. 291:2001;2423-2428
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora Jr., F.C.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
Yamada, M.6
Takahashi, H.7
Tsuji, S.8
Troncoso, J.9
Dawson, V.L.10
-
36
-
-
0028283985
-
Glutamine repeats as polar zippers: Their possible role in inherited neurodegenerative diseases
-
Perutz M.F., Johnson T., Suzuki M., Finch J.T. Glutamine repeats as polar zippers. their possible role in inherited neurodegenerative diseases Proc. Natl. Acad. Sci. USA. 91:1994;5355-5358
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5355-5358
-
-
Perutz, M.F.1
Johnson, T.2
Suzuki, M.3
Finch, J.T.4
-
37
-
-
0032847708
-
Nuclear targeting of mutant Huntingtin increases toxicity
-
Peters M.F., Nucifora F.C. Jr., Kushi J., Seaman H.C., Cooper J.K., Herring W.J., Dawson V.L., Dawson T.M., Ross C.A. Nuclear targeting of mutant Huntingtin increases toxicity. Mol. Cell. Neurosci. 14:1999;121-128
-
(1999)
Mol. Cell. Neurosci.
, vol.14
, pp. 121-128
-
-
Peters, M.F.1
Nucifora Jr., F.C.2
Kushi, J.3
Seaman, H.C.4
Cooper, J.K.5
Herring, W.J.6
Dawson, V.L.7
Dawson, T.M.8
Ross, C.A.9
-
38
-
-
0037174879
-
Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization
-
Poirier M.A., Li H., Macosko J., Cai S., Amzel M., Ross C.A. Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization. J. Biol. Chem. 277:2002;41032-41037
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41032-41037
-
-
Poirier, M.A.1
Li, H.2
MacOsko, J.3
Cai, S.4
Amzel, M.5
Ross, C.A.6
-
39
-
-
0030703686
-
Dynamics of proteasome distribution in living cells
-
Reits E.A., Benham A.M., Plougastel B., Neefjes J., Trowsdale J. Dynamics of proteasome distribution in living cells. EMBO J. 16:1997;6087-6094
-
(1997)
EMBO J.
, vol.16
, pp. 6087-6094
-
-
Reits, E.A.1
Benham, A.M.2
Plougastel, B.3
Neefjes, J.4
Trowsdale, J.5
-
40
-
-
0032846416
-
Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice
-
Saigoh K., Wang Y.L., Suh J.G., Yamanishi T., Sakai Y., Kiyosawa H., Harada T., Ichihara N., Wakana S., Kikuchi T., Wada K. Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice. Nat. Genet. 23:1999;47-51
-
(1999)
Nat. Genet.
, vol.23
, pp. 47-51
-
-
Saigoh, K.1
Wang, Y.L.2
Suh, J.G.3
Yamanishi, T.4
Sakai, Y.5
Kiyosawa, H.6
Harada, T.7
Ichihara, N.8
Wakana, S.9
Kikuchi, T.10
Wada, K.11
-
41
-
-
0037099080
-
The cellular fate of mutant rhodopsin: Quality control, degradation and aggresome formation
-
Saliba R.S., Munro P.M., Luthert P.J., Cheetham M.E. The cellular fate of mutant rhodopsin. quality control, degradation and aggresome formation J. Cell Sci. 115:2002;2907-2918
-
(2002)
J. Cell Sci.
, vol.115
, pp. 2907-2918
-
-
Saliba, R.S.1
Munro, P.M.2
Luthert, P.J.3
Cheetham, M.E.4
-
42
-
-
0032475931
-
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
-
Saudou F., Finkbeiner S., Devys D., Greenberg M.E. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell. 95:1998;55-66
-
(1998)
Cell
, vol.95
, pp. 55-66
-
-
Saudou, F.1
Finkbeiner, S.2
Devys, D.3
Greenberg, M.E.4
-
43
-
-
3042717240
-
Cellular toxicity of polyglutamine expansion proteins; Mechanism of transcription factor deactivation
-
Schaffar G., Breuer P., Boteva R., Behrends C., Tzvetkov N., Strippel N., Sakahira H., Siegers K., Hayer-Hartl M., Hartl F.U. Cellular toxicity of polyglutamine expansion proteins; mechanism of transcription factor deactivation. Mol. Cell. 15:2004;95-105
-
(2004)
Mol. Cell
, vol.15
, pp. 95-105
-
-
Schaffar, G.1
Breuer, P.2
Boteva, R.3
Behrends, C.4
Tzvetkov, N.5
Strippel, N.6
Sakahira, H.7
Siegers, K.8
Hayer-Hartl, M.9
Hartl, F.U.10
-
44
-
-
0033551063
-
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington's disease pathology
-
Scherzinger E., Sittler A., Schweiger K., Heiser V., Lurz R., Hasenbank R., Bates G.P., Lehrach H., Wanker E.E. Self-assembly of polyglutamine- containing huntingtin fragments into amyloid-like fibrils. implications for Huntington's disease pathology Proc. Natl. Acad. Sci. USA. 96:1999;4604-4609
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4604-4609
-
-
Scherzinger, E.1
Sittler, A.2
Schweiger, K.3
Heiser, V.4
Lurz, R.5
Hasenbank, R.6
Bates, G.P.7
Lehrach, H.8
Wanker, E.E.9
-
45
-
-
0036198110
-
Protein surveillance machinery in brains with spinocerebellar ataxia type 3: Redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions
-
Schmidt T., Lindenberg K.S., Krebs A., Schols L., Laccone F., Herms J., Rechsteiner M., Riess O., Landwehrmeyer G.B. Protein surveillance machinery in brains with spinocerebellar ataxia type 3. redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions Ann. Neurol. 51:2002;302-310
-
(2002)
Ann. Neurol.
, vol.51
, pp. 302-310
-
-
Schmidt, T.1
Lindenberg, K.S.2
Krebs, A.3
Schols, L.4
Laccone, F.5
Herms, J.6
Rechsteiner, M.7
Riess, O.8
Landwehrmeyer, G.B.9
-
46
-
-
0036798685
-
Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components
-
Stenoien D.L., Mielke M., Mancini M.A. Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components. Nat. Cell Biol. 4:2002;806-810
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 806-810
-
-
Stenoien, D.L.1
Mielke, M.2
Mancini, M.A.3
-
47
-
-
1842472483
-
Caspase activation inhibits proteasome function during apoptosis
-
Sun X.M., Butterworth M., MacFarlane M., Dubiel W., Ciechanover A., Cohen G.M. Caspase activation inhibits proteasome function during apoptosis. Mol. Cell. 14:2004;81-93
-
(2004)
Mol. Cell
, vol.14
, pp. 81-93
-
-
Sun, X.M.1
Butterworth, M.2
MacFarlane, M.3
Dubiel, W.4
Ciechanover, A.5
Cohen, G.M.6
-
48
-
-
0027452148
-
Rhodopsin mutations responsible for autosomal dominant retinitis pigmentosa. Clustering of functional classes along the polypeptide chain
-
Sung C.H., Davenport C.M., Nathans J. Rhodopsin mutations responsible for autosomal dominant retinitis pigmentosa. Clustering of functional classes along the polypeptide chain. J. Biol. Chem. 268:1993;26645-26649
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26645-26649
-
-
Sung, C.H.1
Davenport, C.M.2
Nathans, J.3
-
49
-
-
0037077040
-
Toxic proteins in neurodegenerative disease
-
Taylor J.P., Hardy J., Fischbeck K.H. Toxic proteins in neurodegenerative disease. Science. 296:2002;1991-1995
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
50
-
-
0037388418
-
Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein
-
Taylor J.P., Tanaka F., Robitschek J., Sandoval C.M., Taye A., Markovic-Plese S., Fischbeck K.H. Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein. Hum. Mol. Genet. 12:2003;749-757
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 749-757
-
-
Taylor, J.P.1
Tanaka, F.2
Robitschek, J.3
Sandoval, C.M.4
Taye, A.5
Markovic-Plese, S.6
Fischbeck, K.H.7
-
51
-
-
0037415751
-
From Alzheimer to Huntington: Why is a structural understanding so difficult?
-
Temussi P.A., Masino L., Pastore A. From Alzheimer to Huntington. why is a structural understanding so difficult? EMBO J. 22:2003;355-361
-
(2003)
EMBO J.
, vol.22
, pp. 355-361
-
-
Temussi, P.A.1
Masino, L.2
Pastore, A.3
-
52
-
-
0033134869
-
Aggregates in neurodegenerative disease: Crowds and power?
-
Tran P.B., Miller R.J. Aggregates in neurodegenerative disease. crowds and power? Trends Neurosci. 22:1999;194-197
-
(1999)
Trends Neurosci.
, vol.22
, pp. 194-197
-
-
Tran, P.B.1
Miller, R.J.2
-
53
-
-
1842766144
-
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
-
Venkatraman P., Wetzel R., Tanaka M., Nukina N., Goldberg A.L. Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins. Mol. Cell. 14:2004;95-104
-
(2004)
Mol. Cell
, vol.14
, pp. 95-104
-
-
Venkatraman, P.1
Wetzel, R.2
Tanaka, M.3
Nukina, N.4
Goldberg, A.L.5
-
54
-
-
0037108725
-
Aggregate formation inhibits proteasomal degradation of polyglutamine proteins
-
Verhoef L.G., Lindsten K., Masucci M.G., Dantuma N.P. Aggregate formation inhibits proteasomal degradation of polyglutamine proteins. Hum. Mol. Genet. 11:2002;2689-2700
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2689-2700
-
-
Verhoef, L.G.1
Lindsten, K.2
Masucci, M.G.3
Dantuma, N.P.4
-
55
-
-
0033791230
-
Protein aggregation and pathogenesis of Huntington's disease: Mechanisms and correlations
-
Wanker E.E. Protein aggregation and pathogenesis of Huntington's disease. mechanisms and correlations Biol. Chem. 381:2000;937-942
-
(2000)
Biol. Chem.
, vol.381
, pp. 937-942
-
-
Wanker, E.E.1
-
56
-
-
0032879437
-
Membrane filter assay for detection of amyloid-like polyglutamine- containing protein aggregates
-
Wanker E.E., Scherzinger E., Heiser V., Sittler A., Eickhoff H., Lehrach H. Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates. Methods Enzymol. 309:1999;375-386
-
(1999)
Methods Enzymol.
, vol.309
, pp. 375-386
-
-
Wanker, E.E.1
Scherzinger, E.2
Heiser, V.3
Sittler, A.4
Eickhoff, H.5
Lehrach, H.6
|