Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 29, 2004, Pages 10810-10814

  Yao, Dongdong ^a   Gu, Zezong ^a   Nakamura, Tomohiro ^a   Shi, Zhong Qing ^a   Ma, Yuliang ^a   Gaston, Benjamin ^b   Palmer, Lisa A ^b   Rockenstein, Edward M ^c   Zhang, Zhuohua ^a   Masliah, Eliezer ^c   Uehara, Takashi ^a   Lipton, Stuart A ^a  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PARKIN; PROTEASOME; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; GENE FUNCTION; GENE MUTATION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOTOR DYSFUNCTION; NERVE CELL NECROSIS; NEUROPATHOLOGY; NITROSATION; NITROSYLATION; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN MODIFICATION; STRESS; UBIQUITINATION; WILD TYPE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; AMINO ACID SEQUENCE; ANIMALS; HUMANS; MICE; MICE, KNOCKOUT; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NITROSATION; OXIDATIVE STRESS; PARKINSON DISEASE; PEPTIDE MAPPING; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; ROTENONE; S-NITROSOTHIOLS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UNCOUPLING AGENTS;

EID: 3242733689     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0404161101     Document Type: Article

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