Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

Journal of Biological Chemistry

Volumn 272, Issue 36, 1997, Pages 22642-22647

  Salceda, Susana ^a   Caro, Jaime ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; LUCIFERASE; PROTEASOME;

ANIMAL CELL; ARTICLE; DNA FLANKING REGION; ENZYME ACTIVITY; HYPOXIA; MAMMAL; NONHUMAN; OXIDATION REDUCTION REACTION; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION;

CELL LINE; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; HYDROLYSIS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MULTIENZYME COMPLEXES; NUCLEAR PROTEINS; OXIDATION-REDUCTION; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; TRANSCRIPTION FACTORS; UBIQUITINS;

ANIMALIA; MAMMALIA;

EID: 0030961006     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.36.22642     Document Type: Article

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