Ubiquitin-activating enzyme (E1) isoforms in lens epithelial cells: Origin of translation, E2 specificity and cellular localization determined with novel site-specific antibodies

Experimental Eye Research

Volumn 73, Issue 6, 2001, Pages 827-836

  Shang, Fu ^a   Deng, Gejing ^b   Obin, Martin ^a   Wu, Christina C N ^a   Gong, Xin ^a   Smith, Donald ^a   Laursen, Richard A ^b   Andley, Usha P ^c   Reddan, John R ^d   Taylor, Allen ^a  

^a TUFTS UNIVERSITY   (United States)

^b Boston University   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d OAKLAND UNIVERSITY   (United States)

Author keywords

E1; E2; Translation; Ubiquitin

Indexed keywords

CARRIER PROTEIN; ENZYME ANTIBODY; ISOENZYME; MESSENGER RNA; UBIQUITIN CARRIER PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CODON; CONTROLLED STUDY; ENZYME LOCALIZATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LENS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; TRANSLATION INITIATION; UBIQUITINATION;

EID: 0035701458     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.2001.1091     Document Type: Article

References (32)

1. Histone ubiquitination and chromatin remodeling in mouse spermatogenesis
2. Intracellular protein degradation in cultured bovine epithelial cells
3. A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division
4. Regulation of nuclear transport and degradation of the Xenopus cyclin-dependent kinase inhibitor, p27Xic1
5. The proteasome, a novel protease regulated by multiple mechanisms
6. Mechanism of binding of multivalent immune complexes to Fc receptors. 2. Kinetics of binding
7. Ubiquitin mRNA is a major stress-induced transcript in mammalian cells
8. Immunogenic structure of the influenza virus hemagglutinin
9. Nuclear localization of the ubiquitin-activating enzyme, E1, is cell-cycle-dependent
10. Coordinated induction of the ubiquitin conjugation pathway accompanies the developmentally programmed death of insect skeletal muscle
11. Ubiquitin-activating enzyme, mechanism and role in protein-ubiquitin conjugation
12. Molecular cloning, sequence and tissue distribution of human ubiquitin-activating enzyme E1
13. Human ubiquitin-activating enzyme, E1. Indication of potential nuclear and cytoplasmic subpopulations using epitope-tagged cDNA constructs
14. The ubiquitin system
15. Bovine lens epithelial cells have a ubiquitin-dependent proteolysis system
16. Ubiquitin and the enigma of intracellular protein degradation
17. Changes in the structure and function of the multicatalytic proteinase (proteasome) during programmed cell death in the intersegmental muscles of the hawkmoth, Manduca sexta
18. Resistance to cadmium mediated by ubiquitin-dependent proteolysis
19. The maturation of lens cells: A morphological study
20. Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization
21. Activation of a UBC4-dependent pathway of ubiquitin conjugation during postnatal development of the rat testis
22. The multicatalytic and 26 S proteases
23. Activation of polyubiquitin gene expression during developmentally programmed cell death
24. Ubiquitin-dependent pathway is up-regulated in differentiating lens cells
25. Activity of ubiquitin dependent pathway in response to oxidative stress: Ubiquitin activating enzyme (E1) is transiently up-regulated
26. The ubiquitin-activating enzyme E1 is phosphorylated and localized to the nucleus in a cell cycle-dependent manner
27. Identification of a region within the ubiquitin-activating enzyme required for nuclear targeting and phosphorylation
28. The ubiquitin system and the N-end rule pathway
29. Induction of ubiquitin-conjugating enzymes during terminal erythroid differentiation
30. Ubiquitin-dependent signaling: The role of ubiquitination in the response of cells to their environment
31. Ubiquitin-protein conjugates selectively distribute during early chicken embryogenesis
32. MDM2-dependent ubiquitination of nuclear and cytoplasmic P53