Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: A possible mechanism for RPE aging and age-related macular degeneration

Experimental Eye Research

Volumn 76, Issue 4, 2003, Pages 397-403

  Liang, Fong Qi ^a,b   Godley, Bernard F ^a,b  

^a RETINA FOUNDATION OF THE SOUTHWEST   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Aging; AMD; DNA damage; Mitochondria; Oxidative stress; RPE

Indexed keywords

CELL NUCLEUS DNA; HYDROGEN PEROXIDE; MITOCHONDRIAL DNA;

ANTIOXIDANT ACTIVITY; APOPTOSIS; CELL AGING; CORRELATION ANALYSIS; DISEASE COURSE; DNA DAMAGE; DNA REPAIR; HUMAN; MEASUREMENT; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PIGMENT EPITHELIUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETINA MACULA AGE RELATED DEGENERATION; RETINA ROD OUTER SEGMENT; REVIEW; THEORY; AGING; GENETICS; PATHOLOGY; RETINA MACULA DEGENERATION;

AGING; DNA DAMAGE; DNA REPAIR; DNA, MITOCHONDRIAL; HUMANS; MACULAR DEGENERATION; OXIDATIVE STRESS; PIGMENT EPITHELIUM OF EYE;

EID: 0037375044     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4835(03)00023-X     Document Type: Review

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