Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

Journal of Biological Chemistry

Volumn 278, Issue 4, 2003, Pages 2396-2402

  Stewart, Daniel ^a,b   Killeen, Erin ^a   Naquin, Ryan ^a   Alam, Safdar ^a   Alam, Jawed ^a,b,c  

^a OCHSNER CLINIC FOUNDATION   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; BIOSYNTHESIS; ENZYME INHIBITION; PROTEINS; RNA;

PROTEASOME INHIBITION;

GENES;

CADMIUM; HEME OXYGENASE 1; MESSENGER RNA; PROTEASOME; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; UBIQUITIN; UNCLASSIFIED DRUG; CYCLOHEXIMIDE; CYSTEINE PROTEINASE; DNA BINDING PROTEIN; MULTIENZYME COMPLEX; NFE2L2 PROTEIN, MOUSE; PROTEIN SYNTHESIS INHIBITOR; RNA; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; DNA BINDING; ENZYME ASSAY; GENE ACTIVATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HEPATOMA CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; CHEMISTRY; DOSE RESPONSE; METABOLISM; PROTEIN BINDING; TIME; WESTERN BLOTTING;

ANIMALIA;

ANIMALS; BLOTTING, WESTERN; CADMIUM; CYCLOHEXIMIDE; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MULTIENZYME COMPLEXES; NF-E2-RELATED FACTOR 2; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN SYNTHESIS INHIBITORS; RNA; RNA, MESSENGER; TIME FACTORS; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; UBIQUITIN;

EID: 0037462651     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209195200     Document Type: Article

References (48)

1. Morano, K. A., and Thiele, D. J. (1999) Gene Expr. 7, 271-282
2. Karin, M., Liu, Z., and Zandi, E. (1997) Curr. Opin. Cell Biol. 9, 240-246
3. Karin, M., Takahashi, T., Kapahi, P., Delhase, M., Chen, Y., Makris, C., Rothwarf, D., Baud, V., Natoli, G., Guido, F., and Li, N. (2001) Biofactors 15, 87-89
4. Moi, P., Chan, K., Asunis, I., Cao, A., and Kan, Y. W. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9926-9930
5. Itoh, K., Igarashi, K., Hayashi, N., Nishizawa, M., and Yamamoto, M. (1995) Mol. Cell. Biol. 15, 4184-4193
6. Marini, M. G., Chan, K., Casula, L., Kan, Y. W., Cao, A., and Moi, P. (1997) J. Biol. Chem. 272, 16490-16497
7. Venugopal, R., and Jaiswal, A. K. (1998) Oncogene 17, 3145-3156
8. He, C. H., Gong, P., Hu, B., Stewart, D., Choi, M. E., Choi, A. M., and Alam, J. (2001) J. Biol. Chem. 276, 20858-20865
9. Kataoka, K., Noda, M., and Nishizawa, M. (1994) Mol. Cell. Biol. 14, 700-712
10. Rushmore, T. H., Morton, M. R., and Pickett, C. B. (1991) J. Biol. Chem. 266, 11632-11639
11. Choi, A. M., and Alam, J. (1996) Am. J. Respir. Cell Mol. Biol. 15, 9-19
12. Venugopal, R., and Jaiswal, A. K. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14960-14965
13. Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., Yamamoto, M., and Nabeshima, Y. (1997) Biochem. Biophys. Res. Commun. 236, 313-322
14. Moinova, H. R., and Mulcahy, R. T. (1999) Biochem. Biophys. Res. Commun. 261, 661-668
15. Wild, A. C., Moinova, H. R., and Mulcahy, R. T. (1999) J. Biol. Chem. 274, 33627-33636
16. Huang, H. C., Nguyen, T., and Pickett, C. B. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 12475-12480
17. Nguyen, T., Huang, H. C., and Pickett, C. B. (2000) J. Biol. Chem. 275, 15466-15473
18. Alam, J., Stewart, D., Touchard, C., Boinapally, S., Choi, A. M., and Cook, J. L. (1999) J. Biol. Chem. 274, 26071-26078
19. Kim, Y. C., Masutani, H., Yamaguchi, Y., Itoh, K., Yamamoto, M., and Yodoi, J. (2001) J. Biol. Chem. 276, 18399-18406
20. Chan, K., and Kan, Y. W. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 12731-12736
21. Chan, K., Han, X. D., and Kan, Y. W. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 4611-4616
22. Enomoto, A., Itoh, K., Nagayoshi, E., Haruta, J., Kimura, T., O'Connor, T., Harada, T., and Yamamoto, M. (2001) Toxicol. Sci. 59, 169-177
23. Ramos-Gomez, M., Kwak, M. K., Dolan, P. M., Itoh, K., Yamamoto, M., Talalay, P., and Kensler, T. W. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 3410-3415
24. Ishii, T., Itoh, K., Takahashi, S., Sato, H., Yanagawa, T., Katoh, Y., Bannai, S., and Yamamoto, M. (2000) J. Biol. Chem. 275, 16023-16029
25. Kobayashi, M., Itoh, K., Suzuki, T., Osanai, H., Nishikawa, K., Katoh, Y., Takagi, Y., and Yamamoto, M. (2002) Genes Cells 7, 807-820
26. Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D., and Yamamoto, M. (1999) Genes Dev. 13, 76-86
27. Zipper, L. M., and Mulcahy, R. T. (2002) J. Biol. Chem. 277, 36544-36552
28. Sekhar, K. R., Spitz, D. R., Harris, S., Nguyen, T. T., Meredith, M. J., Holt, J. T., Guis, D., Marnett, L. J., Summar, M. L., and Freeman, M. L. (2002) Free Radic. Biol. Med. 32, 650-662
29. Dinkova-Kostova, A. T., Holtzclaw, W. D., Cole, R. N., Itoh, K., Wakabayashi, N., Katoh, Y., Yamamoto, M., and Talalay, P. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 11908-11913
30. Dhakshinamoorthy, S., and Jaiswal, A. K. (2001) Oncogene 20, 3906-3917
31. Jeyapaul, J., and Jaiswal, A. K. (2000) Biochem. Pharmacol. 59, 1433-1439
32. Kwak, M. K., Itoh, K., Yamamoto, M., and Kensler, T. W. (2002) Mol. Cell. Biol. 22, 2883-2892
33. Chomczynski, P., and Sacchi, N. (1987) Anal. Biochem. 162, 156-159
34. Alam, J., Shibahara, S., and Smith, A. (1989) J. Biol. Chem. 264, 6371-6375
35. Alam, J., Wicks, C., Stewart, D., Gong, P., Touchard, C., Otterbein, S., Choi, A. M., Burow, M. E., and Tou, J. (2000) J. Biol. Chem. 275, 27694-27702
36. Gong, P., Hu, B., Stewart, D., Ellerbe, M., Figueroa, Y. G., Blank, V., Beckman, B. S., and Alam, J. (2001) J. Biol. Chem. 276, 27018-27025
37. Treier, M., Staszewski, L. M., and Bohmann, D. (1994) Cell 78, 787-798
38. Alam, J. (2000) Functional Analysis of the Heme Oxygenase-1 Gene Promoter: Vol. 1. Current Protocols in Toxicology (Maines, M. D., Costa, L. G., Reed, D. J., Sassa, S., and Sipes, I. G., eds) pp. 9.7.1-9.7.21, John Wiley & Sons, Inc., New York
39. Gong, P., Stewart, D., Hu, B., Li, N., Cook, J., Nel, A., and Alam, J. (2002) Antioxid. Redox Signal. 4, 249-257
40. Hershko, A., and Ciechanover, A. (1998) Annu. Rev. Biochem. 67, 425-479
41. Sutter, C. H., Laughner, E., and Semenza, G. L. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4748-4753
42. Campanero, M. R., and Flemington, E. K. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2221-2226
43. Molinari, E., Gilman, M., and Natesan, S. (1999) EMBO J. 18, 6439-6447
44. Rechsteiner, M., and Rogers, S. W. (1996) Trends Biochem. Sci. 21, 267-271
45. Rogers, S., Wells, R., and Rechsteiner, M. (1986) Science 234, 364-368
46. Alkalay, I., Yaron, A., Hatzubai, A., Orian, A., Ciechanover, A., and Ben-Neriah, Y. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10599-10603
47. Chen, Z., Hagler, J., Palombella, V. J., Melandri, F., Scherer, D., Ballard, D., and Maniatis, T. (1995) Genes Dev. 9, 1586-1597
48. Takeda, K., Ishizawa, S., Sato, M., Yoshida, T., and Shibahara, S. (1994) J. Biol. Chem. 269, 22858-22867