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Volumn 13, Issue 1, 1999, Pages 76-86

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Author keywords

ARE; Electrophile; Keap1; Nrf2; Oxidative stress

Indexed keywords

REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR;

EID: 0032953192     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.1.76     Document Type: Article
Times cited : (3056)

References (41)
  • 1
    • 0029019008 scopus 로고
    • Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcriptional enhancer
    • Alam, J., S. Camhi, and A.M.K. Choi. 1995. Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcriptional enhancer. J. Biol. Chem. 270: 11977-11984.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11977-11984
    • Alam, J.1    Camhi, S.2    Choi, A.M.K.3
  • 2
    • 0029099016 scopus 로고
    • The BTB/POZ domain: A new protein-protein interaction motif common to DNA- and actin-binding proteins
    • Albagli, O., P. Dhordain, C. Deweindt, G. Lecocq, and D. Leprince. 1995. The BTB/POZ domain: A new protein-protein interaction motif common to DNA- and actin-binding proteins. Cell Growth Differ. 6: 1193-1198.
    • (1995) Cell Growth Differ. , vol.6 , pp. 1193-1198
    • Albagli, O.1    Dhordain, P.2    Deweindt, C.3    Lecocq, G.4    Leprince, D.5
  • 3
    • 0020508747 scopus 로고
    • Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative disease
    • Ames, B.N. 1983. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative disease. Science 221: 1256-1264.
    • (1983) Science , vol.221 , pp. 1256-1264
    • Ames, B.N.1
  • 4
    • 0021348393 scopus 로고
    • Induction of cystine and glutamate transport activity in human fibroblasts by diethylmaleate and other electrophilic agents
    • Bannai, S. 1984. Induction of cystine and glutamate transport activity in human fibroblasts by diethylmaleate and other electrophilic agents. J. Biol. Chem. 264: 2435-2440.
    • (1984) J. Biol. Chem. , vol.264 , pp. 2435-2440
    • Bannai, S.1
  • 5
    • 0028040875 scopus 로고
    • The POZ domain: A conserved protein-protein interaction motif
    • Bardwell, V.J. and R. Treisman. 1994. The POZ domain: A conserved protein-protein interaction motif. Genes & Dev. 8: 1664-1677.
    • (1994) Genes & Dev. , vol.8 , pp. 1664-1677
    • Bardwell, V.J.1    Treisman, R.2
  • 6
    • 0020021436 scopus 로고
    • Erythroblast cell lines transformed by a ts mutant of avian erythroblastosis virus: A model system to study erythroid differentiation in vitro
    • Beug, H., G. Doederlien, C. Freudenstein, and T. Graf. 1982. Erythroblast cell lines transformed by a ts mutant of avian erythroblastosis virus: A model system to study erythroid differentiation in vitro. J. Cell. Physiol. (Suppl.) 1: 195-207.
    • (1982) J. Cell. Physiol. (Suppl.) , vol.1 , pp. 195-207
    • Beug, H.1    Doederlien, G.2    Freudenstein, C.3    Graf, T.4
  • 7
    • 0030698250 scopus 로고    scopus 로고
    • The Maf transcription factors: Regulators of differentiation
    • Blank, V. and N.C. Andrews. 1997. The Maf transcription factors: Regulators of differentiation. Trends. Biochem. Sci. 22: 437-441.
    • (1997) Trends. Biochem. Sci. , vol.22 , pp. 437-441
    • Blank, V.1    Andrews, N.C.2
  • 8
    • 0028231273 scopus 로고
    • Drosophila Kelch motif is derived from a common enzyme fold
    • Bork, P. and R.F. Doolittle. 1994. Drosophila Kelch motif is derived from a common enzyme fold. J. Mol. Biol. 236: 1277-1282.
    • (1994) J. Mol. Biol. , vol.236 , pp. 1277-1282
    • Bork, P.1    Doolittle, R.F.2
  • 9
    • 0027209420 scopus 로고
    • The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos
    • Bowerman, B., B.W. Draper, C.C. Mello, and J.R. Priess. 1993. The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos. Cell 74: 443-452.
    • (1993) Cell , vol.74 , pp. 443-452
    • Bowerman, B.1    Draper, B.W.2    Mello, C.C.3    Priess, J.R.4
  • 10
    • 0028856209 scopus 로고
    • Induction of phase I and phase II drug metabolizing enzyme mRNA, protein and activity by BHA, ethoxyquin and oltipraz
    • Buetler, T.M., E.P. Gallagher, C. Wang, D.L. Stahl, J.D. Hayes, and D.L. Eaton. 1995. Induction of phase I and phase II drug metabolizing enzyme mRNA, protein and activity by BHA, ethoxyquin and oltipraz. Toxicol. Appl. Pharmacol. 135: 45-57.
    • (1995) Toxicol. Appl. Pharmacol. , vol.135 , pp. 45-57
    • Buetler, T.M.1    Gallagher, E.P.2    Wang, C.3    Stahl, D.L.4    Hayes, J.D.5    Eaton, D.L.6
  • 11
    • 0024280908 scopus 로고
    • Developmental regulation of β-globin switching
    • Choi, O.R. and J.D. Engel. 1988. Developmental regulation of β-globin switching. Cell 55: 17-26.
    • (1988) Cell , vol.55 , pp. 17-26
    • Choi, O.R.1    Engel, J.D.2
  • 12
    • 0028947208 scopus 로고
    • cDNA cloning of murine Nrf2 gene, coding for a p45 NF-E2 related transcription factor
    • Chui, D.H.K., W. Tang, and S.H. Orkin. 1995. cDNA cloning of murine Nrf2 gene, coding for a p45 NF-E2 related transcription factor. Biochem. Biophys. Res. Commun. 209: 40-46.
    • (1995) Biochem. Biophys. Res. Commun. , vol.209 , pp. 40-46
    • Chui, D.H.K.1    Tang, W.2    Orkin, S.H.3
  • 13
    • 0025145723 scopus 로고
    • Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element
    • Friling, R.S., S. Bensimon, and V. Daniel. 1990. Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element. Proc. Natl. Acad. Sci. 87: 6258-6262.
    • (1990) Proc. Natl. Acad. Sci. , vol.87 , pp. 6258-6262
    • Friling, R.S.1    Bensimon, S.2    Daniel, V.3
  • 15
    • 0029561598 scopus 로고
    • The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isozymes to cancer chemoprevcntion and drug resistance
    • Hayes, J.D. and J.D. Pulford. 1995. The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isozymes to cancer chemoprevcntion and drug resistance. Crit. Rev. Biochem. Mol. Biol. 30: 445-600.
    • (1995) Crit. Rev. Biochem. Mol. Biol. , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, J.D.2
  • 16
    • 0030989488 scopus 로고    scopus 로고
    • ENC-1: A novel mammalian Kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein
    • Hernandez, M-C., P.J. Andres-Barquin, S. Martinez, A. Bulfone, J.L.R. Rubenstein, and M.A. Israel. 1997. ENC-1: A novel mammalian Kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein. J. Neuroscience 17: 3038-3051.
    • (1997) J. Neuroscience , vol.17 , pp. 3038-3051
    • Hernandez, M.-C.1    Andres-Barquin, P.J.2    Martinez, S.3    Bulfone, A.4    Rubenstein, J.L.R.5    Israel, M.A.6
  • 17
    • 0028118492 scopus 로고
    • Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins
    • Igarashi, K., K. Kataoka, K. Itoh, N. Hayashi, M. Nishizawa, and M. Yamamoto. 1994. Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 367: 568-572.
    • (1994) Nature , vol.367 , pp. 568-572
    • Igarashi, K.1    Kataoka, K.2    Itoh, K.3    Hayashi, N.4    Nishizawa, M.5    Yamamoto, M.6
  • 18
    • 0028290823 scopus 로고
    • Crystal structure of a free radical enzyme, galactose oxidase
    • Ito, N., S.E.V. Phillips, K.D.S. Yadav, and P.E. Knowles. 1994. Crystal structure of a free radical enzyme, galactose oxidase. J. Mol. Biol. 238: 794-814.
    • (1994) J. Mol. Biol. , vol.238 , pp. 794-814
    • Ito, N.1    Phillips, S.E.V.2    Yadav, K.D.S.3    Knowles, P.E.4
  • 19
    • 0029043995 scopus 로고
    • Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small maf family proteins
    • Itoh, K., K. Igarashi, N. Hayashi, M. Nishizawa, and M. Yamamoto. 1995. Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small maf family proteins. Mol. Cell. Biol. 15: 4184-4193.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4184-4193
    • Itoh, K.1    Igarashi, K.2    Hayashi, N.3    Nishizawa, M.4    Yamamoto, M.5
  • 21
    • 0027954409 scopus 로고
    • Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun
    • Kataoka, K., M. Noda, and M. Nishizawa. 1994. Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun. Mol. Cell. Biol. 14: 700-712.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 700-712
    • Kataoka, K.1    Noda, M.2    Nishizawa, M.3
  • 23
    • 0023649184 scopus 로고
    • A new class of yeast transcriptional activators
    • Ma, J. and M. Ptashne. 1987. A new class of yeast transcriptional activators. Cell 51: 113-119.
    • (1987) Cell , vol.51 , pp. 113-119
    • Ma, J.1    Ptashne, M.2
  • 24
    • 0014757218 scopus 로고
    • Carcinogenesis by chemicals: An overview. G.H.A. Clowes memorial lecture
    • Miller, J.A. 1970. Carcinogenesis by chemicals: An overview. G.H.A. Clowes Memorial Lecture. Cancer Res. 39: 559-576.
    • (1970) Cancer Res. , vol.39 , pp. 559-576
    • Miller, J.A.1
  • 25
    • 0000742893 scopus 로고
    • pEF-BOS, a powerful mammalian expression vector
    • Mizushima, S. and S. Nagata. 1994. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18: 5332.
    • (1994) Nucleic Acids Res. , vol.18 , pp. 5332
    • Mizushima, S.1    Nagata, S.2
  • 26
    • 0028061444 scopus 로고
    • Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the β-globin locus control region
    • Moi, P., K. Chan, I. Asunis, A. Cao, and Y.W. Kan. 1994. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the β-globin locus control region. Proc. Natl. Acad. Sci. 91: 9926-9930.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 9926-9930
    • Moi, P.1    Chan, K.2    Asunis, I.3    Cao, A.4    Kan, Y.W.5
  • 27
    • 0017645084 scopus 로고    scopus 로고
    • Continuous tissue cell lines derived from chemically induced tumors of Japanese quail
    • Moscovici, C., M. Giovannella, M.H. Jimenez, M.M.C. Lai, M.J. Haman, and P.K. Vogt. 1997. Continuous tissue cell lines derived from chemically induced tumors of Japanese quail. Cell 11: 95-103.
    • (1997) Cell , vol.11 , pp. 95-103
    • Moscovici, C.1    Giovannella, M.2    Jimenez, M.H.3    Lai, M.M.C.4    Haman, M.J.5    Vogt, P.K.6
  • 29
    • 0029655169 scopus 로고
    • Prediction of the coding sequences of unidentified human genes, IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1
    • Nagase, T., N. Seki, A. Tanaka, K. Ishikawa, and N. Nomura. 1995. Prediction of the coding sequences of unidentified human genes, IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 2: 164-174.
    • (1995) DNA Res. , vol.2 , pp. 164-174
    • Nagase, T.1    Seki, N.2    Tanaka, A.3    Ishikawa, K.4    Nomura, N.5
  • 30
    • 0027988156 scopus 로고
    • Interaction between collagen-binding stress protein HSP47 and collagen
    • Natsume, T., T. Koide, S. Yokota, K. Hirayoshi, and K. Nagata. 1994. Interaction between collagen-binding stress protein HSP47 and collagen. J. Biol. Chem. 269: 31224-31228.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31224-31228
    • Natsume, T.1    Koide, T.2    Yokota, S.3    Hirayoshi, K.4    Nagata, K.5
  • 31
    • 0027487416 scopus 로고
    • The elcctrophile counterattack response: Protection against neoplasia and toxicity
    • Prestera, T., Y. Zhang, R.S. Spencer, A.C. Wilczak, and P. Talalay. 1993a. The elcctrophile counterattack response: Protection against neoplasia and toxicity. Adv. Enzyme Regul. 33: 281-296.
    • (1993) Adv. Enzyme Regul. , vol.33 , pp. 281-296
    • Prestera, T.1    Zhang, Y.2    Spencer, R.S.3    Wilczak, A.C.4    Talalay, P.5
  • 32
    • 0027394238 scopus 로고
    • Chemical and molecular regulation of enzymes that detoxify carcinogens
    • Prestera, T., W.D. Holtzclaw, Y. Zhang, and P. Talalay. 1993b. Chemical and molecular regulation of enzymes that detoxify carcinogens. Proc. Natl. Acad. Sci. 90: 2965-2969.
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 2965-2969
    • Prestera, T.1    Holtzclaw, W.D.2    Zhang, Y.3    Talalay, P.4
  • 34
    • 0030838880 scopus 로고    scopus 로고
    • Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein Costal2
    • Robbins, D.J., K.E. Nybakken, R. Kobayashi, J.C. Sisson, J.M. Bishop, and P.P. Therond. 1997. Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein Costal2. Cell 90: 225-234.
    • (1997) Cell , vol.90 , pp. 225-234
    • Robbins, D.J.1    Nybakken, K.E.2    Kobayashi, R.3    Sisson, J.C.4    Bishop, J.M.5    Therond, P.P.6
  • 37
    • 0016328890 scopus 로고
    • Metabolic activation of benzo(a)pyrene proceeds by a diolepoxide
    • Sims, P., P. L. Grover, A. Swaisland, K. Pal, and A. Hewer. 1974. Metabolic activation of benzo(a)pyrene proceeds by a diolepoxide. Nature 252: 326-329.
    • (1974) Nature , vol.252 , pp. 326-329
    • Sims, P.1    Grover, P.L.2    Swaisland, A.3    Pal, K.4    Hewer, A.5
  • 38
    • 0030754171 scopus 로고    scopus 로고
    • Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway
    • Sisson, J.C., K.S. Ho, K. Suyama, and M.P. Scott. 1997. Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway. Cell 90: 235-245.
    • (1997) Cell , vol.90 , pp. 235-245
    • Sisson, J.C.1    Ho, K.S.2    Suyama, K.3    Scott, M.P.4
  • 40
    • 0017917866 scopus 로고
    • Inhibitors of chemical carcinogenesis
    • Wattenberg, L.W. 1978. Inhibitors of chemical carcinogenesis. Adv. Cancer Res. 26: 197-226.
    • (1978) Adv. Cancer Res. , vol.26 , pp. 197-226
    • Wattenberg, L.W.1
  • 41
    • 0027403024 scopus 로고
    • Kelch encodes a component of intracellular bridges in Drosophila egg chambers
    • Xue, F. and L. Cooley. 1993. Kelch encodes a component of intracellular bridges in Drosophila egg chambers. Cell 72: 681-693.
    • (1993) Cell , vol.72 , pp. 681-693
    • Xue, F.1    Cooley, L.2


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