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Volumn 292, Issue 5516, 2001, Pages 464-468
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HIFα targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
a a a a a a a a a a |
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Author keywords
[No Author keywords available]
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Indexed keywords
HYDROXYLATION;
IRON;
PROTEINS;
TUMORS;
CELLULAR ADAPTATION;
OXYGEN;
HYPOXIA INDUCIBLE FACTOR 1ALPHA;
OXYGEN;
PROLINE;
TUMOR PROTEIN;
UBIQUITIN PROTEIN LIGASE;
BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR;
COBALT;
COBALT CHLORIDE;
DEFEROXAMINE;
HYBRID PROTEIN;
HYDROXYPROLINE;
HYPOXIA INDUCIBLE FACTOR 2, ALPHA SUBUNIT;
HYPOXIA-INDUCIBLE FACTOR 2, ALPHA SUBUNIT;
LIGASE;
PROTEIN;
TRANSACTIVATOR PROTEIN;
TRANSCRIPTION FACTOR;
TUMOR SUPPRESSOR PROTEIN;
UBIQUITIN;
VHL PROTEIN, HUMAN;
VON HIPPEL LINDAU PROTEIN;
AMINO ACID SUBSTITUTION;
ARTICLE;
HYDROXYLATION;
HYPOXIA;
NONHUMAN;
OXYGEN CONCENTRATION;
PRIORITY JOURNAL;
PROTEIN ANALYSIS;
PROTEIN BINDING;
PROTEIN MODIFICATION;
VON HIPPEL LINDAU DISEASE;
AMINO ACID SEQUENCE;
ANIMAL;
CELL CULTURE;
CELL HYPOXIA;
CELL LINE;
CHEMISTRY;
GENETICS;
HUMAN;
MASS SPECTROMETRY;
METABOLISM;
MOLECULAR GENETICS;
MOUSE;
PHYSIOLOGY;
PROTEIN TERTIARY STRUCTURE;
MAMMALIA;
AMINO ACID SEQUENCE;
ANIMALS;
BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS;
CELL HYPOXIA;
CELL LINE;
COBALT;
DEFEROXAMINE;
HUMANS;
HYDROXYLATION;
HYDROXYPROLINE;
LIGASES;
MASS SPECTROMETRY;
MICE;
MOLECULAR SEQUENCE DATA;
OXYGEN;
PROTEIN STRUCTURE, TERTIARY;
PROTEINS;
RECOMBINANT FUSION PROTEINS;
TRANS-ACTIVATORS;
TRANSCRIPTION FACTORS;
TUMOR CELLS, CULTURED;
TUMOR SUPPRESSOR PROTEINS;
UBIQUITIN-PROTEIN LIGASES;
UBIQUITINS;
VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;
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EID: 0035917313
PISSN: 00368075
EISSN: None
Source Type: Journal
DOI: 10.1126/science.1059817 Document Type: Article |
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Times cited : (4141)
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References (35)
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