A foldable CFTRΔF508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase

Journal of Cell Biology

Volumn 167, Issue 6, 2004, Pages 1075-1085

  Younger, J Michael ^a   Ren, Hong Yu ^a   Chen, Liling ^a   Fan, Chun Yang ^a   Fields, Andrea ^a   Patterson, Cam ^a   Cyr, Douglas M ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; HEAT SHOCK COGNATE PROTEIN 70; PROTEASOME; PROTEIN CFTRDELTAF508; PROTEIN CHIP; PROTEIN HDJ2; TRANSMEMBRANE CONDUCTANCE REGULATOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CYSTIC FIBROSIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; TEMPERATURE; UBIQUITINATION;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; HSC70 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IRON-BINDING PROTEINS; MOLECULAR CHAPERONES; PROTEIN FOLDING; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES;

EID: 11244349206     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200410065     Document Type: Article

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