IL-1β-induced monocyte chemoattractant protein-1 gene expression in endothelial cells is blocked by proteasome inhibitors

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 18, Issue 6, 1998, Pages 934-940

  Parry, Graham C N ^b   Martin, Teresa ^a   Felts, Katherine A ^a   Cobb, Ronald R ^a  

^a Tanabe Research Laboratories   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Endothelial cells; Monocyte chemoattractant protein 1; Proteasome inhibitors

Indexed keywords

INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEASOME; ACETYLLEUCYL LEUCYL NORLEUCINAL; ACETYLLEUCYL-LEUCYL-NORLEUCINAL; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LEUPEPTIN; MULTIENZYME COMPLEX; SERINE PROTEINASE INHIBITOR; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL MIGRATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY;

CELLS, CULTURED; CHEMOKINE CCL2; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1; LEUPEPTINS; MULTIENZYME COMPLEXES; NF-KAPPA B; PROTEASOME ENDOPEPTIDASE COMPLEX; SERINE PROTEINASE INHIBITORS; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

EID: 0031595185     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.18.6.934     Document Type: Article

References (14)

1. Oppenheim JJ, Zachariae COC, Mukaida N, Matsushima K. Properties of the novel proinflammatory supergene 'intercrine' cytokine family. Annu Rev Immunol. 1991;9:617-648.
2. Schall TJ. Biology of the RANTES/SIS cytokine family. Cytokine. 1991;3:165-183.
3. Leonard EJ, Yoshimura T. Human monocyte chemoattractant protein-1 (MCP-1). Immunol Today. 1990;11:97-101.
4. Collotta F, Borre A, Wang JM, Tattanelli M, Maddalena F, Polentarutti N, Peri G, Mantovani A. Expression of a monocytic cytokine by human mononuclear phagocytes. J Immunol. 1992;148:760-765.
5. Rollins BJ, Stier P, Ernst T, Wong GG. The human homolog of the JE gene encodes a monocyte secretory protein. Mol Cell Biol. 1989;9:4687-4695.
6. Rollins BJ, Pober JS. Interleukin-4 induces the synthesis and secretion of MCP-1/JE by human endothelial cells. Am J Pathol. 1991;138:1315-1319.
7. Rovin BH, Yoshimura T, Tan L. Cytokine-induced production of monocyte chemoattractant protein-1 by cultured human mesangial cells. J Immunol. 1992;148:2148-2153.
8. Shyy Y, Li Y, Kolattukudy PE. Activation of MCP-1 gene expression is mediated through multiple signaling pathways. Biochem Biophys Res Commun. 1993;192:693-699.
9. Sica A, Wang JM, Collotta F, Dejana E, Mantovani A, Oppenheim JJ, Larsen CG, Zachariae COC, Matsushima K. Monocyte chemotactic and activating factor gene expression induced in endothelial cells by IL-1 and tumor necrosis factor. J Immunol. 1990;144:3034-3038.
10. Villiger PM, Terkeltaub R, Lotz M. Production of monocyte chemoattractant protein-1 by inflamed synovial tissue and cultured synoviocytes. J Immunol. 1992;149:722-727.
11. Takeya M, Yoshimura T, Leonard EJ, Takahashi K. Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody. Hum Pathol. 1993;24:534-539.
12. Yla-Herttuala S, Lipton BA, Rosenfeld ME, Sarkioja T, Yoshimura T, Leonard EJ, Witztum JL, Steinberg D. Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc Natl Acad Sci USA. 1991;88:5252-5256.
13. Shyy Y, Li Y, Kolattukudy PE. Structure of human monocyte chemoattractant protein gene and its regulation by TPA. Biochem Biophys Res Commun. 1990;169:346-351.
14. Ueda A, Okuda K, Ohno S, Shirai A, Igarashi T, Matsunaga K, Fukushima J, Kawamoto S, Ishigatsubo Y, Okubo T. NF-κB and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene. J Immunol. 1994;153:2052-2063.