Curcumin protects retinal cells from light-and oxidant stress-induced cell death

Free Radical Biology and Medicine

Volumn 46, Issue 5, 2009, Pages 672-679

  Mandal, Md Nawajes A ^a,b   Patlolla, Jagan M R ^c   Zheng, Lixin ^a,b   Agbaga, Martin Paul ^a,b   Tran, Julie Thu A ^a,b   Wicker, Lea ^a,b   Kasus Jacobi, Anne ^a,b   Elliott, Michael H ^a,b   Rao, Chinthalapally V ^c   Anderson, Robert E ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

AMD; Curcumin; Light induced retinal degeneration; Photoreceptors; Retina

Indexed keywords

CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE B; THIOREDOXIN; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; LIGHT STRESS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA CELL; RETINA DEGENERATION; UPREGULATION;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CURCUMIN; CYTOPROTECTION; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; GENE EXPRESSION PROFILING; HUMANS; LIGHT; MACULAR DEGENERATION; MICE; NF-KAPPA B; OXIDATIVE STRESS; PHYTOTHERAPY; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, WISTAR; RETINAL CONE PHOTORECEPTOR CELLS; TRANSCRIPTIONAL ACTIVATION;

RATTUS;

EID: 59249104565     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.12.006     Document Type: Article

References (65)

1. Mukherjee P.K., and Wahile A. Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. J. Ethnopharmacol. 103 (2006) 25-35
2. Ammon H.P., and Wahl M.A. Pharmacology of Curcuma longa. Planta Med. 57 (1991) 1-7
3. Hatcher H., Planalp R., Cho J., Torti F.M., and Torti S.V. Curcumin: from ancient medicine to current clinical trials. Cell. Mol. Life Sci. 65 (2008) 1631-1652
4. Goel A., Kunnumakkara A.B., and Aggarwal B.B. Curcumin as "Curecumin": from kitchen to clinic. Biochem. Pharmacol. 75 (2008) 787-809
5. Rao C.V. Regulation of COX and LOX by curcumin. Adv. Exp. Med. Biol. 595 (2007) 213-226
6. Shishodia S., Sethi G., and Aggarwal B.B. Curcumin: getting back to the roots. Ann. N. Y. Acad. Sci. 1056 (2005) 206-217
7. Abe Y., Hashimoto S., and Horie T. Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol. Res. 39 (1999) 41-47
8. Reddy A.C., and Lokesh B.R. Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes. Mol. Cell. Biochem. 111 (1992) 117-124
9. Huang M.T., Lysz T., Ferraro T., Abidi T.F., Laskin J.D., and Conney A.H. Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 51 (1991) 813-819
10. Singh S., and Aggarwal B.B. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J. Biol. Chem. 270 (1995) 24995-25000
11. Woo J.H., Kim Y.H., Choi Y.J., Kim D.G., Lee K.S., Bae J.H., Min D.S., Chang J.S., Jeong Y.J., Lee Y.H., Park J.W., and Kwon T.K. Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt. Carcinogenesis 24 (2003) 1199-1208
12. Susan M., and Rao M.N. Induction of glutathione S-transferase activity by curcumin in mice. Arzneim.-Forsch. 42 (1992) 962-964
13. Scapagnini G., Colombrita C., Amadio M., D'Agata V., Arcelli E., Sapienza M., Quattrone A., and Calabrese V. Curcumin activates defensive genes and protects neurons against oxidative stress. Antioxid. Redox Signal. 8 (2006) 395-403
14. Balogun E., Hoque M., Gong P., Killeen E., Green C.J., Foresti R., Alam J., and Motterlini R. Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem. J. 371 (2003) 887-895
15. Hollyfield J.G., Bonilha V.L., Rayborn M.E., Yang X., Shadrach K.G., Lu L., Ufret R.L., Salomon R.G., and Perez V.L. Oxidative damage-induced inflammation initiates age-related macular degeneration. Nat. Med. 14 (2008) 194-198
16. Donoso L.A., Kim D., Frost A., Callahan A., and Hageman G. The role of inflammation in the pathogenesis of age-related macular degeneration. Surv. Ophthalmol. 51 (2006) 137-152
17. Shen J.K., Dong A., Hackett S.F., Bell W.R., Green W.R., and Campochiaro P.A. Oxidative damage in age-related macular degeneration. Histol. Histopathol. 22 (2007) 1301-1308
18. Madsen-Bouterse S.A., and Kowluru R.A. Oxidative stress and diabetic retinopathy: Pathophysiological mechanisms and treatment perspectives. Rev. Endocr. Metab. Disorders 9 (2008) 315-327
19. Kern T.S. Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Exp. Diabetes Res. 2007 (2007) 95103
20. Kowluru R.A., and Kanwar M. Effects of curcumin on retinal oxidative stress and inflammation in diabetes. Nutr. Metab. 4 (2007) 8
21. Demontis G.C., Longoni B., and Marchiafava P.L. Molecular steps involved in light-induced oxidative damage to retinal rods. Invest. Ophthalmol. Visual Sci. 43 (2002) 2421-2427
22. Wiegand R.D., Giusto N.M., Rapp L.M., and Anderson R.E. Evidence for rod outer segment lipid peroxidation following constant illumination of the rat retina. Invest. Ophthalmol. Visual Sci. 24 (1983) 1433-1435
23. Specht S., Leffak M., Darrow R.M., and Organisciak D.T. Damage to rat retinal DNA induced in vivo by visible light. Photochem. Photobiol. 69 (1999) 91-98
24. Tanito M., Elliott M.H., Kotake Y., and Anderson R.E. Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina. Invest. Ophthalmol. Visual Sci. 46 (2005) 3859-3868
25. Tanito, M.; Brush, R. S.; Elliott, M. H.; Wicker, L. D.; Henry, K. R.; Anderson, R. E. 615 High levels of retinal membrane docosahexaenoic acid increase susceptibility to Q2616 stress-induced degeneration. J. Lipid Res.; in press.
26. Organisciak D.T., Wang H.M., Li Z.Y., and Tso M.O. The protective effect of ascorbate in retinal light damage of rats. Invest. Ophthalmol. Visual Sci. 26 (1985) 1580-1588
27. Organisciak D.T., Darrow R.M., Jiang Y.I., Marak G.E., and Blanks J.C. Protection by dimethylthiourea against retinal light damage in rats. Invest. Ophthalmol. Visual Sci. 33 (1992) 1599-1609
28. Tanito M., Masutani H., Nakamura H., Ohira A., and Yodoi J. Cytoprotective effect of thioredoxin against retinal photic injury in mice. Invest. Ophthalmol. Visual Sci. 43 (2002) 1162-1167
29. Kaldi I., Dittmar M., Pierce P., and Anderson R.E. L-NAME protects against acute light damage in albino rats, but not against retinal degeneration in P23H and S334ter transgenic rats. Exp. Eye Res. 76 (2003) 453-461
30. Ranchon I., LaVail M.M., Kotake Y., and Anderson R.E. Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration. J. Neurosci. 23 (2003) 6050-6057
31. Tanito M., Li F., Elliott M.H., Dittmar M., and Anderson R.E. Protective effect of TEMPOL derivatives against light-induced retinal damage in rats. Invest. Ophthalmol. Visual Sci. 48 (2007) 1900-1905
32. Tan E., Ding X.Q., Saadi A., Agarwal N., Naash M.I., and Al-Ubaidi M.R. Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice. Invest. Ophthalmol. Visual Sci. 45 (2004) 764-768
33. Jaiswal A.S., Marlow B.P., Gupta N., and Narayan S. Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells. Oncogene 21 (2002) 8414-8427
34. Mandal M.N., Vasireddy V., Jablonski M.M., Wang X., Heckenlively J.R., Hughes B.A., Reddy G.B., and Ayyagari R. Spatial and temporal expression of MFRP and its interaction with CTRP5. Invest. Ophthalmol. Visual Sci. 47 (2006) 5514-5521
35. Mandal M.N., Vasireddy V., Reddy G.B., Wang X., Moroi S.E., Pattnaik B.R., Hughes B.A., Heckenlively J.R., Hitchcock P.F., Jablonski M.M., and Ayyagari R. CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion. Invest. Ophthalmol. Visual Sci. 47 (2006) 5505-5513
36. Tanito M., Kaidzu S., Ohira A., and Anderson R.E. Topography of retinal damage in light-exposed albino rats. Exp. Eye Res. 87 (2008) 292-295
37. Catala A. Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions. Chem. Phys. Lipids (2008)
38. Mattson M.P. Dietary factors, hormesis and health. Ageing Res. Rev. 7 (2008) 43-48
39. Mrudula T., Suryanarayana P., Srinivas P.N., and Reddy G.B. Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina. Biochem. Biophys. Res. Commun. 361 (2007) 528-532
40. Matteucci A., Frank C., Domenici M.R., Balduzzi M., Paradisi S., Carnovale-Scalzo G., Scorcia G., and Malchiodi-Albedi F. Curcumin treatment protects rat retinal neurons against excitotoxicity: effect on N-methyl-D-aspartate-induced intracellular Ca(2+) increase. Exp. Brain Res. Exp. Hirnforschung. 167 (2005) 641-648
41. Marc R.E., Jones B.W., Watt C.B., Vazquez-Chona F., Vaughan D.K., and Organisciak D.T. Extreme retinal remodeling triggered by light damage: implications for age related macular degeneration. Mol. Vision 14 (2008) 782-806
42. Yamamoto M., Lidia K., Gong H., Onitsuka S., Kotani T., and Ohira A. Changes in manganese superoxide dismutase expression after exposure of the retina to intense light. Histochem. J. 31 (1999) 81-87
43. Mittag T.W., Bayer A.U., and La V.M. Light-induced retinal damage in mice carrying a mutated SOD I gene. Exp. Eye Res. 69 (1999) 677-683
44. Hashizume K., Hirasawa M., Imamura Y., Noda S., Shimizu T., Shinoda K., Kurihara T., Noda K., Ozawa Y., Ishida S., Miyake Y., Shirasawa T., and Tsubota K. Retinal dysfunction and progressive retinal cell death in SOD1-deficient mice. Am. J. Pathol. 172 (2008) 1325-1331
45. Li Z.L., Lam S., and Tso M.O. Desferrioxamine ameliorates retinal photic injury in albino rats. Curr. Eye Res. 10 (1991) 133-144
46. Rohrer B., Guo Y., Kunchithapautham K., and Gilkeson G.S. Eliminating complement factor D reduces photoreceptor susceptibility to light-induced damage. Invest. Ophthalmol. Visual Sci. 48 (2007) 5282-5289
47. Tanito M., Nishiyama A., Tanaka T., Masutani H., Nakamura H., Yodoi J., and Ohira A. Change of redox status and modulation by thiol replenishment in retinal photooxidative damage. Invest. Ophthalmol. Visual Sci. 43 (2002) 2392-2400
48. Wu T., Chen Y., Chiang S.K., and Tso M.O. NF-kappaB activation in light-induced retinal degeneration in a mouse model. Invest. Ophthalmol. Vis. Sci. 43 (2002) 2834-2840
49. Bhakar A.L., Tannis L.L., Zeindler C., Russo M.P., Jobin C., Park D.S., MacPherson S., and Barker P.A. Constitutive nuclear factor-kappa B activity is required for central neuron survival. J. Neurosci. 22 (2002) 8466-8475
50. Karin M., and Delhase M. The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling. Semin. Immunol. 12 (2000) 85-98
51. Karin M., and Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu. Rev. Immunol. 18 (2000) 621-663
52. Mattson M.P., and Cheng A. Neurohormetic phytochemicals: low-dose toxins that induce adaptive neuronal stress responses. Trends Neurosci. 29 (2006) 632-639
53. Watson J.L., Hill R., Lee P.W., Giacomantonio C.A., and Hoskin D.W. Curcumin induces apoptosis in HCT-116 human colon cancer cells in a p21-independent manner. Exp. Mol. Pathol. 84 (2008) 230-233
54. Tanito M., Agbaga M.P., and Anderson R.E. Upregulation of thioredoxin system via Nrf2-antioxidant responsive element pathway in adaptive-retinal neuroprotection in vivo and in vitro. Free Radic. Biol. Med. 42 (2007) 1838-1850
55. Maltzman J.S., Carmen J.A., and Monroe J.G. Transcriptional regulation of the Icam-1 gene in antigen receptor-and phorbol ester-stimulated B lymphocytes: role for transcription factor EGR1. J. Exp. Med. 183 (1996) 1747-1759
56. Knapska E., and Kaczmarek L. A gene for neuronal plasticity in the mammalian brain: Zif268/Egr-1/NGFI-A/Krox-24/TIS8/ZENK?. Prog. Neurobiol. 74 (2004) 183-211
57. Pendurthi U.R., and Rao L.V. Suppression of transcription factor Egr-1 by curcumin. Thromb. Res. 97 (2000) 179-189
58. Giri R.K., Rajagopal V., and Kalra V.K. Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor. J. Neurochem. 91 (2004) 1199-1210
59. Chen A., Xu J., and Johnson A.C. Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1. Oncogene 25 (2006) 278-287
60. Ravindranath V., and Chandrasekhara N. Absorption and tissue distribution of curcumin in rats. Toxicology 16 (1980) 259-265
61. Ravindranath V., and Chandrasekhara N. Metabolism of curcumin-studies with [3H]curcumin. Toxicology 22 (1981) 337-344
62. Shankar T.N., Shantha N.V., Ramesh H.P., Murthy I.A., and Murthy V.S. Toxicity studies on turmeric (Curcuma longa): acute toxicity studies in rats, guineapigs and monkeys. Indian J. Exp. Biol. 18 (1980) 73-75
63. Wang Q., Sun A.Y., Simonyi A., Jensen M.D., Shelat P.B., Rottinghaus G.E., MacDonald R.S., Miller D.K., Lubahn D.E., Weisman G.A., and Sun G.Y. Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits. J. Neurosci. Res. 82 (2005) 138-148
64. Wu A., Ying Z., and Gomez-Pinilla F. Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition. Exp. Neurol. 197 (2006) 309-317
65. Lim G.P., Chu T., Yang F., Beech W., Frautschy S.A., and Cole G.M. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 21 (2001) 8370-8377