Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation

EMBO Journal

Volumn 20, Issue 18, 2001, Pages 5197-5206

  Masson, N ^a   Willam, C ^a   Maxwell, P H ^a   Pugh, C W ^a   Ratcliffe, P J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Destruction domai; Hypoxia inducible factor ; Prolyl hydroxylation; Ubiquitylation; Von Hippel Lindau protein

Indexed keywords

CELL EXTRACT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; PROLINE; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; ENZYME BINDING; ENZYME SUBSTRATE COMPLEX; HYDROXYLATION; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INDUCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATTLE; CELL EXTRACTS; CONSERVED SEQUENCE; CYTOPLASM; DNA-BINDING PROTEINS; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIGASES; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROLINE; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 0035903468     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.18.5197     Document Type: Article

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