Site-specific methionine oxidation initiates calmodulin degradation by the 20S proteasome

Biochemistry

Volumn 48, Issue 13, 2009, Pages 3005-3016

  Balog, Edward M ^a,b   Lockamy, Elizabeth L ^a   Thomas, David D ^a   Ferrington, Deborah A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CALMODULIN MUTANTS; CIRCULAR DICHROISMS; EXPERIMENTAL APPROACHES; IN CELLS; INDUCED LOSS; METHIONINE OXIDATIONS; MOLECULAR SIGNALS; N TERMINALS; PROTEASOME; PROTEIN QUALITY CONTROLS; SECONDARY STRUCTURES; SELECTIVE DEGRADATIONS; SITE SPECIFICS; SITE-DIRECTED MUTAGENESIS; SITE-SELECTIVE; SPECTROSCOPIC MEASUREMENTS; WILD TYPES;

DEGRADATION; DICHROISM; ENZYME ACTIVITY; OXIDATION; PROTEINS; QUALITY ASSURANCE; QUALITY FUNCTION DEPLOYMENT; SIGNAL TRANSDUCTION; THERMODYNAMIC STABILITY; TOTAL QUALITY MANAGEMENT;

BIODEGRADATION;

CALMODULIN; LEUCINE; METHIONINE; METHIONINE SULFOXIDE; PROTEASOME;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL ANALYSIS; CIRCULAR DICHROISM; MEASUREMENT; MOLECULAR WEIGHT; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY; SUBSTITUTION REACTION; THERMODYNAMICS;

AMINO ACID SEQUENCE; ANIMALS; CALMODULIN; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; METHIONINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; OXIDATION-REDUCTION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; SUS SCROFA; THERMODYNAMICS;

EID: 65249117450     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi802117k     Document Type: Article

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