메뉴 건너뛰기




Volumn 98, Issue C, 2011, Pages 85-131

Therapeutic targets for neuroprotection and/or enhancement of functional recovery following traumatic brain injury

Author keywords

Clinical; Preclinical; Primary injury; Secondary injury

Indexed keywords


EID: 78650896188     PISSN: 18771173     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385506-0.00003-X     Document Type: Chapter
Times cited : (12)

References (286)
  • 3
    • 0142247196 scopus 로고    scopus 로고
    • National estimates of hospitalization charges for the acute care of traumatic brain injuries
    • M. Schootman, T.G. Buchman, and L.M. Lewis National estimates of hospitalization charges for the acute care of traumatic brain injuries Brain Inj 17 2003 983 990
    • (2003) Brain Inj , vol.17 , pp. 983-990
    • Schootman, M.1    Buchman, T.G.2    Lewis, L.M.3
  • 5
    • 38949126991 scopus 로고    scopus 로고
    • Using a cost-benefit analysis to estimate outcomes of a clinical treatment guideline: Testing the Brain Trauma Foundation guidelines for the treatment of severe traumatic brain injury
    • M. Faul, M.M. Wald, W. Rutland-Brown, E.E. Sullivent, and R.W. Sattin Using a cost-benefit analysis to estimate outcomes of a clinical treatment guideline: testing the Brain Trauma Foundation guidelines for the treatment of severe traumatic brain injury J Trauma 63 2007 1271 1278
    • (2007) J Trauma , vol.63 , pp. 1271-1278
    • Faul, M.1    Wald, M.M.2    Rutland-Brown, W.3    Sullivent, E.E.4    Sattin, R.W.5
  • 6
    • 45949098091 scopus 로고    scopus 로고
    • Ten-year outcomes following traumatic brain injury: A population-based cohort
    • C.M. Cameron, D.M. Purdie, E.V. Kliewer, and R.J. McClure Ten-year outcomes following traumatic brain injury: a population-based cohort Brain Inj 22 2008 437 449
    • (2008) Brain Inj , vol.22 , pp. 437-449
    • Cameron, C.M.1    Purdie, D.M.2    Kliewer, E.V.3    McClure, R.J.4
  • 7
    • 0037312746 scopus 로고    scopus 로고
    • Characterization and correlates of medical and rehabilitation charges for traumatic brain injury during acute rehabilitation hospitalization
    • N.H. Mayer, J. Pelensky, J. Whyte, and R. Fidler-Sheppard Characterization and correlates of medical and rehabilitation charges for traumatic brain injury during acute rehabilitation hospitalization Arch Phys Med Rehabil 84 2003 242 248
    • (2003) Arch Phys Med Rehabil , vol.84 , pp. 242-248
    • Mayer, N.H.1    Pelensky, J.2    Whyte, J.3    Fidler-Sheppard, R.4
  • 8
    • 0033536483 scopus 로고    scopus 로고
    • Trends in hospitalization associated with traumatic brain injury
    • DOI 10.1001/jama.282.10.954
    • D. Thurman, and J. Guerrero Trends in hospitalization associated with traumatic brain injury Jama 282 1999 954 957 (Pubitemid 29420314)
    • (1999) Journal of the American Medical Association , vol.282 , Issue.10 , pp. 954-957
    • Thurman, D.1    Guerrero, J.2
  • 9
    • 84875382219 scopus 로고    scopus 로고
    • Consensus conference. Rehabilitation of persons with traumatic brain injury. NIH Consensus Development Panel on Rehabilitation of Persons with Traumatic Brain Injury
    • Consensus conference. Rehabilitation of persons with traumatic brain injury. NIH Consensus Development Panel on Rehabilitation of Persons With Traumatic Brain Injury Jama 282 1999 974 983
    • (1999) Jama , vol.282 , pp. 974-983
  • 11
    • 18844408996 scopus 로고    scopus 로고
    • National Institute of Health Bethesda, MD
    • National Institute of Neurological Disorders and Stroke Traumatic brain injury: hope through research 2002 National Institute of Health Bethesda, MD
    • (2002) Traumatic Brain Injury: Hope Through Research
  • 12
    • 28244479761 scopus 로고    scopus 로고
    • Subjective well-being and quality of life following traumatic brain injury in adults: A long-term population-based follow-up
    • T.W. Teasdale, and A.W. Engberg Subjective well-being and quality of life following traumatic brain injury in adults: a long-term population-based follow-up Brain Inj 19 2005 1041 1048
    • (2005) Brain Inj , vol.19 , pp. 1041-1048
    • Teasdale, T.W.1    Engberg, A.W.2
  • 13
    • 34548744669 scopus 로고    scopus 로고
    • Perceived self-efficacy and life satisfaction after traumatic brain injury
    • K.D. Cicerone, and J. Azulay Perceived self-efficacy and life satisfaction after traumatic brain injury J Head Trauma Rehabil 22 2007 257 266
    • (2007) J Head Trauma Rehabil , vol.22 , pp. 257-266
    • Cicerone, K.D.1    Azulay, J.2
  • 15
    • 33751373600 scopus 로고    scopus 로고
    • Patients with mild traumatic brain injury: Immediate and long-term outcome compared to intra-cranial injuries on CT scan
    • C. Sadowski-Cron, J. Schneider, P. Senn, B.P. Radanov, P. Ballinari, and H. Zimmermann Patients with mild traumatic brain injury: immediate and long-term outcome compared to intra-cranial injuries on CT scan Brain Inj 20 2006 1131 1137
    • (2006) Brain Inj , vol.20 , pp. 1131-1137
    • Sadowski-Cron, C.1    Schneider, J.2    Senn, P.3    Radanov, B.P.4    Ballinari, P.5    Zimmermann, H.6
  • 17
    • 39549118756 scopus 로고    scopus 로고
    • Neurocognitive performance of concussed athletes when symptom free
    • S.P. Broglio, S.N. Macciocchi, and M.S. Ferrara Neurocognitive performance of concussed athletes when symptom free J Athl Train 42 2007 504 508
    • (2007) J Athl Train , vol.42 , pp. 504-508
    • Broglio, S.P.1    MacCiocchi, S.N.2    Ferrara, M.S.3
  • 18
    • 33947671368 scopus 로고    scopus 로고
    • Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury
    • D.L. Warden, B. Gordon, T.W. McAllister, J.M. Silver, J.T. Barth, and J. Bruns Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury J Neurotrauma 23 2006 1468 1501
    • (2006) J Neurotrauma , vol.23 , pp. 1468-1501
    • Warden, D.L.1    Gordon, B.2    McAllister, T.W.3    Silver, J.M.4    Barth, J.T.5    Bruns, J.6
  • 19
    • 0141849462 scopus 로고    scopus 로고
    • Outcome following moderate traumatic brain injury
    • T.W. Vitaz, J. Jenks, G.H. Raque, and C.B. Shields Outcome following moderate traumatic brain injury Surg Neurol 60 2003 285 291 discussion 291
    • (2003) Surg Neurol , vol.60 , pp. 285-291
    • Vitaz, T.W.1    Jenks, J.2    Raque, G.H.3    Shields, C.B.4
  • 22
    • 0141676771 scopus 로고    scopus 로고
    • Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?
    • C. Ikonomidou, and L. Turski Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? Lancet Neurol 1 2002 383 386
    • (2002) Lancet Neurol , vol.1 , pp. 383-386
    • Ikonomidou, C.1    Turski, L.2
  • 23
    • 67849135779 scopus 로고    scopus 로고
    • Combination therapies for traumatic brain injury: Prospective considerations
    • S. Margulies, and R. Hicks Combination therapies for traumatic brain injury: prospective considerations J Neurotrauma 26 2009 925 939
    • (2009) J Neurotrauma , vol.26 , pp. 925-939
    • Margulies, S.1    Hicks, R.2
  • 26
    • 29044447857 scopus 로고    scopus 로고
    • Experimental models of traumatic brain injury: Do we really need to build a better mousetrap?
    • D.M. Morales, N. Marklund, D. Lebold, H.J. Thompson, A. Pitkanen, and W.L. Maxwell Experimental models of traumatic brain injury: do we really need to build a better mousetrap? Neuroscience 136 2005 971 989
    • (2005) Neuroscience , vol.136 , pp. 971-989
    • Morales, D.M.1    Marklund, N.2    Lebold, D.3    Thompson, H.J.4    Pitkanen, A.5    Maxwell, W.L.6
  • 27
    • 0027396850 scopus 로고
    • Mechanisms of brain injury
    • T.A. Gennarelli Mechanisms of brain injury J Emerg Med 11 Suppl. 1 1993 5 11
    • (1993) J Emerg Med , vol.11 , Issue.SUPPL. 1 , pp. 5-11
    • Gennarelli, T.A.1
  • 28
    • 0347990376 scopus 로고    scopus 로고
    • The neurophysiology of brain injury
    • M. Gaetz The neurophysiology of brain injury Clin Neurophysiol 115 2004 4 18
    • (2004) Clin Neurophysiol , vol.115 , pp. 4-18
    • Gaetz, M.1
  • 29
    • 26844501218 scopus 로고    scopus 로고
    • Animal models of head trauma
    • I. Cernak Animal models of head trauma NeuroRx 2 2005 410 422
    • (2005) NeuroRx , vol.2 , pp. 410-422
    • Cernak, I.1
  • 30
    • 0023807637 scopus 로고
    • Controlled cortical impact: A new experimental brain injury model
    • J.W. Lighthall Controlled cortical impact: a new experimental brain injury model J Neurotrauma 5 1988 1 15
    • (1988) J Neurotrauma , vol.5 , pp. 1-15
    • Lighthall, J.W.1
  • 32
    • 0029054671 scopus 로고
    • A model of parasagittal controlled cortical impact in the mouse: Cognitive and histopathologic effects
    • D.H. Smith, H.D. Soares, J.S. Pierce, K.G. Perlman, K.E. Saatman, and D.F. Meaney A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effects J Neurotrauma 12 1995 169 178
    • (1995) J Neurotrauma , vol.12 , pp. 169-178
    • Smith, D.H.1    Soares, H.D.2    Pierce, J.S.3    Perlman, K.G.4    Saatman, K.E.5    Meaney, D.F.6
  • 33
    • 0037884982 scopus 로고    scopus 로고
    • The induction of N-methyl-D-aspartate receptor-dependent long-term potentiation
    • G.L. Collingridge The induction of N-methyl-D-aspartate receptor-dependent long-term potentiation Philos Trans R Soc Lond B Biol Sci 358 2003 635 641
    • (2003) Philos Trans R Soc Lond B Biol Sci , vol.358 , pp. 635-641
    • Collingridge, G.L.1
  • 34
    • 33747627893 scopus 로고    scopus 로고
    • Molecular mechanism of neuronal plasticity: Induction and maintenance of long-term potentiation in the hippocampus
    • E. Miyamoto Molecular mechanism of neuronal plasticity: induction and maintenance of long-term potentiation in the hippocampus J Pharmacol Sci 100 2006 433 442
    • (2006) J Pharmacol Sci , vol.100 , pp. 433-442
    • Miyamoto, E.1
  • 37
    • 0028586835 scopus 로고
    • Increased transmitter amino acid concentration in human ventricular CSF after brain trauma
    • A.M. Palmer, D.W. Marion, M.L. Botscheller, D.M. Bowen, and S.T. DeKosky Increased transmitter amino acid concentration in human ventricular CSF after brain trauma NeuroReport 6 1994 153 156
    • (1994) NeuroReport , vol.6 , pp. 153-156
    • Palmer, A.M.1    Marion, D.W.2    Botscheller, M.L.3    Bowen, D.M.4    Dekosky, S.T.5
  • 38
    • 0027295901 scopus 로고
    • Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans
    • A.J. Baker, R.J. Moulton, V.H. MacMillan, and P.M. Shedden Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans J Neurosurg 79 1993 369 372
    • (1993) J Neurosurg , vol.79 , pp. 369-372
    • Baker, A.J.1    Moulton, R.J.2    MacMillan, V.H.3    Shedden, P.M.4
  • 39
    • 0034923108 scopus 로고    scopus 로고
    • Excitatory amino acids in cerebrospinal fluid of patients with acute head injuries
    • H. Zhang, X. Zhang, T. Zhang, and L. Chen Excitatory amino acids in cerebrospinal fluid of patients with acute head injuries Clin Chem 47 2001 1458 1462
    • (2001) Clin Chem , vol.47 , pp. 1458-1462
    • Zhang, H.1    Zhang, X.2    Zhang, T.3    Chen, L.4
  • 40
    • 41149168714 scopus 로고    scopus 로고
    • Endogenous melatonin increases in cerebrospinal fluid of patients after severe traumatic brain injury and correlates with oxidative stress and metabolic disarray
    • M.A. Seifman, A.A. Adamides, P.N. Nguyen, S.A. Vallance, D.J. Cooper, and T. Kossmann Endogenous melatonin increases in cerebrospinal fluid of patients after severe traumatic brain injury and correlates with oxidative stress and metabolic disarray J Cereb Blood Flow Metab 28 2008 684 696
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 684-696
    • Seifman, M.A.1    Adamides, A.A.2    Nguyen, P.N.3    Vallance, S.A.4    Cooper, D.J.5    Kossmann, T.6
  • 41
    • 85009295914 scopus 로고    scopus 로고
    • Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans
    • J.I. Brown, A.J. Baker, S.J. Konasiewicz, and R.J. Moulton Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans J Neurotrauma 15 1998 253 263
    • (1998) J Neurotrauma , vol.15 , pp. 253-263
    • Brown, J.I.1    Baker, A.J.2    Konasiewicz, S.J.3    Moulton, R.J.4
  • 42
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • A.I. Faden, P. Demediuk, S.S. Panter, and R. Vink The role of excitatory amino acids and NMDA receptors in traumatic brain injury Science 244 1989 798 800
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 45
    • 77952999203 scopus 로고    scopus 로고
    • Diffuse brain injury elevates tonic glutamate levels and potassium-evoked glutamate release in discrete brain regions at two days post-injury: An enzyme-based microelectrode array study
    • J.M. Hinzman, T.C. Thomas, J.J. Burmeister, J.E. Quintero, P. Huettl, and F. Pomerleau Diffuse brain injury elevates tonic glutamate levels and potassium-evoked glutamate release in discrete brain regions at two days post-injury: an enzyme-based microelectrode array study J Neurotrauma 27 2010 889 899
    • (2010) J Neurotrauma , vol.27 , pp. 889-899
    • Hinzman, J.M.1    Thomas, T.C.2    Burmeister, J.J.3    Quintero, J.E.4    Huettl, P.5    Pomerleau, F.6
  • 46
    • 0034846740 scopus 로고    scopus 로고
    • Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat
    • F.K. van Landeghem, J.F. Stover, I. Bechmann, W. Bruck, A. Unterberg, and C. Buhrer Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat Glia 35 2001 167 179
    • (2001) Glia , vol.35 , pp. 167-179
    • Van Landeghem, F.K.1    Stover, J.F.2    Bechmann, I.3    Bruck, W.4    Unterberg, A.5    Buhrer, C.6
  • 47
    • 4444333138 scopus 로고    scopus 로고
    • Injury-induced alterations in N-methyl-D-aspartate receptor subunit composition contribute to prolonged 45calcium accumulation following lateral fluid percussion
    • C.L. Osteen, C.C. Giza, and D.A. Hovda Injury-induced alterations in N-methyl-D-aspartate receptor subunit composition contribute to prolonged 45calcium accumulation following lateral fluid percussion Neuroscience 128 2004 305 322
    • (2004) Neuroscience , vol.128 , pp. 305-322
    • Osteen, C.L.1    Giza, C.C.2    Hovda, D.A.3
  • 48
    • 33645061251 scopus 로고    scopus 로고
    • Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition
    • M.N. DeRidder, M.J. Simon, R. Siman, Y.P. Auberson, R. Raghupathi, and D.F. Meaney Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition Neurobiol Dis 22 2006 165 176
    • (2006) Neurobiol Dis , vol.22 , pp. 165-176
    • Deridder, M.N.1    Simon, M.J.2    Siman, R.3    Auberson, Y.P.4    Raghupathi, R.5    Meaney, D.F.6
  • 49
    • 50149109081 scopus 로고    scopus 로고
    • Inhibition of NR2B phosphorylation restores alterations in NMDA receptor expression and improves functional recovery following traumatic brain injury in mice
    • J. Schumann, G.A. Alexandrovich, A. Biegon, and R. Yaka Inhibition of NR2B phosphorylation restores alterations in NMDA receptor expression and improves functional recovery following traumatic brain injury in mice J Neurotrauma 25 2008 945 957
    • (2008) J Neurotrauma , vol.25 , pp. 945-957
    • Schumann, J.1    Alexandrovich, G.A.2    Biegon, A.3    Yaka, R.4
  • 50
    • 1842636595 scopus 로고    scopus 로고
    • Dynamic changes in N-methyl-D-aspartate receptors after closed head injury in mice: Implications for treatment of neurological and cognitive deficits
    • A. Biegon, P.A. Fry, C.M. Paden, A. Alexandrovich, J. Tsenter, and E. Shohami Dynamic changes in N-methyl-D-aspartate receptors after closed head injury in mice: implications for treatment of neurological and cognitive deficits Proc Natl Acad Sci USA 101 2004 5117 5122
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 5117-5122
    • Biegon, A.1    Fry, P.A.2    Paden, C.M.3    Alexandrovich, A.4    Tsenter, J.5    Shohami, E.6
  • 51
    • 0036926718 scopus 로고    scopus 로고
    • Time-dependent changes in rat brain cholinergic receptor expression after experimental brain injury
    • S.L. Verbois, S.W. Scheff, and J.R. Pauly Time-dependent changes in rat brain cholinergic receptor expression after experimental brain injury J Neurotrauma 19 2002 1569 1585
    • (2002) J Neurotrauma , vol.19 , pp. 1569-1585
    • Verbois, S.L.1    Scheff, S.W.2    Pauly, J.R.3
  • 52
    • 0024502818 scopus 로고
    • D-cycloserine: A ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristics
    • W.F. Hood, R.P. Compton, and J.B. Monahan D-cycloserine: a ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristics Neurosci Lett 98 1989 91 95
    • (1989) Neurosci Lett , vol.98 , pp. 91-95
    • Hood, W.F.1    Compton, R.P.2    Monahan, J.B.3
  • 53
    • 0025166178 scopus 로고
    • Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor
    • G. Henderson, J.W. Johnson, and P. Ascher Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor J Physiol 430 1990 189 212
    • (1990) J Physiol , vol.430 , pp. 189-212
    • Henderson, G.1    Johnson, J.W.2    Ascher, P.3
  • 54
    • 74149085435 scopus 로고    scopus 로고
    • D-cycloserine improves functional outcome after traumatic brain injury with wide therapeutic window
    • A. Adeleye, E. Shohami, D. Nachman, A. Alexandrovich, V. Trembovler, and R. Yaka D-cycloserine improves functional outcome after traumatic brain injury with wide therapeutic window Eur J Pharmacol 629 2010 25 30
    • (2010) Eur J Pharmacol , vol.629 , pp. 25-30
    • Adeleye, A.1    Shohami, E.2    Nachman, D.3    Alexandrovich, A.4    Trembovler, V.5    Yaka, R.6
  • 55
    • 0030820401 scopus 로고    scopus 로고
    • Morris water maze deficits in rats following traumatic brain injury: Lateral controlled cortical impact
    • S.W. Scheff, S.A. Baldwin, R.W. Brown, and P.J. Kraemer Morris water maze deficits in rats following traumatic brain injury: lateral controlled cortical impact J Neurotrauma 14 1997 615 627
    • (1997) J Neurotrauma , vol.14 , pp. 615-627
    • Scheff, S.W.1    Baldwin, S.A.2    Brown, R.W.3    Kraemer, P.J.4
  • 56
    • 0028788393 scopus 로고
    • Time course of increased vulnerability of cholinergic neurotransmission following traumatic brain injury in the rat
    • C.E. Dixon, S.J. Liu, L.W. Jenkins, M. Bhattachargee, J.S. Whitson, and K. Yang Time course of increased vulnerability of cholinergic neurotransmission following traumatic brain injury in the rat Behav Brain Res 70 1995 125 131
    • (1995) Behav Brain Res , vol.70 , pp. 125-131
    • Dixon, C.E.1    Liu, S.J.2    Jenkins, L.W.3    Bhattachargee, M.4    Whitson, J.S.5    Yang, K.6
  • 57
    • 46149087237 scopus 로고    scopus 로고
    • Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury
    • L.S. Deshpande, D.A. Sun, S. Sombati, A. Baranova, M.S. Wilson, and E. Attkisson Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury Neurosci Lett 441 2008 115 119
    • (2008) Neurosci Lett , vol.441 , pp. 115-119
    • Deshpande, L.S.1    Sun, D.A.2    Sombati, S.3    Baranova, A.4    Wilson, M.S.5    Attkisson, E.6
  • 58
    • 55549085560 scopus 로고    scopus 로고
    • Calcium-permeable AMPA receptors appear in cortical neurons after traumatic mechanical injury and contribute to neuronal fate
    • J.M. Spaethling, D.M. Klein, P. Singh, and D.F. Meaney Calcium-permeable AMPA receptors appear in cortical neurons after traumatic mechanical injury and contribute to neuronal fate J Neurotrauma 25 2008 1207 1216
    • (2008) J Neurotrauma , vol.25 , pp. 1207-1216
    • Spaethling, J.M.1    Klein, D.M.2    Singh, P.3    Meaney, D.F.4
  • 59
    • 3042776205 scopus 로고    scopus 로고
    • Mechanical injury modulates AMPA receptor kinetics via an NMDA receptor-dependent pathway
    • P.B. Goforth, E.F. Ellis, and L.S. Satin Mechanical injury modulates AMPA receptor kinetics via an NMDA receptor-dependent pathway J Neurotrauma 21 2004 719 732
    • (2004) J Neurotrauma , vol.21 , pp. 719-732
    • Goforth, P.B.1    Ellis, E.F.2    Satin, L.S.3
  • 60
    • 0033198298 scopus 로고    scopus 로고
    • Enhancement of AMPA-mediated current after traumatic injury in cortical neurons
    • P.B. Goforth, E.F. Ellis, and L.S. Satin Enhancement of AMPA-mediated current after traumatic injury in cortical neurons J Neurosci 19 1999 7367 7374
    • (1999) J Neurosci , vol.19 , pp. 7367-7374
    • Goforth, P.B.1    Ellis, E.F.2    Satin, L.S.3
  • 61
    • 12244291006 scopus 로고    scopus 로고
    • The glutamate AMPA receptor antagonist, YM872, attenuates cortical tissue loss, regional cerebral edema, and neurological motor deficits after experimental brain injury in rats
    • T. Furukawa, S. Hoshino, S. Kobayashi, T. Asakura, M. Takahashi, and T. Atsumi The glutamate AMPA receptor antagonist, YM872, attenuates cortical tissue loss, regional cerebral edema, and neurological motor deficits after experimental brain injury in rats J Neurotrauma 20 2003 269 278
    • (2003) J Neurotrauma , vol.20 , pp. 269-278
    • Furukawa, T.1    Hoshino, S.2    Kobayashi, S.3    Asakura, T.4    Takahashi, M.5    Atsumi, T.6
  • 62
    • 77950420036 scopus 로고    scopus 로고
    • The glutamate AMPA receptor antagonist, YM872, attenuates regional cerebral edema and IgG immunoreactivity following experimental brain injury in rats
    • T. Atsumi, S. Hoshino, T. Furukawa, S. Kobayashi, T. Asakura, and M. Takahashi The glutamate AMPA receptor antagonist, YM872, attenuates regional cerebral edema and IgG immunoreactivity following experimental brain injury in rats Acta Neurochir Suppl 86 2003 305 307
    • (2003) Acta Neurochir Suppl , vol.86 , pp. 305-307
    • Atsumi, T.1    Hoshino, S.2    Furukawa, T.3    Kobayashi, S.4    Asakura, T.5    Takahashi, M.6
  • 63
    • 0034777483 scopus 로고    scopus 로고
    • Talampanel, a novel noncompetitive AMPA antagonist, is neuroprotective after traumatic brain injury in rats
    • L. Belayev, O.F. Alonso, Y. Liu, A.S. Chappell, W. Zhao, and M.D. Ginsberg Talampanel, a novel noncompetitive AMPA antagonist, is neuroprotective after traumatic brain injury in rats J Neurotrauma 18 2001 1031 1038
    • (2001) J Neurotrauma , vol.18 , pp. 1031-1038
    • Belayev, L.1    Alonso, O.F.2    Liu, Y.3    Chappell, A.S.4    Zhao, W.5    Ginsberg, M.D.6
  • 64
    • 34249083509 scopus 로고    scopus 로고
    • Pharmacology of ampakine modulators: From AMPA receptors to synapses and behavior
    • A.C. Arai, and M. Kessler Pharmacology of ampakine modulators: from AMPA receptors to synapses and behavior Curr Drug Targets 8 2007 583 602
    • (2007) Curr Drug Targets , vol.8 , pp. 583-602
    • Arai, A.C.1    Kessler, M.2
  • 65
    • 77957716183 scopus 로고    scopus 로고
    • The ampakine, Org 26576, bolsters early spatial reference learning and retrieval in the Morris water maze: A subchronic, dose-ranging study in rats
    • E. Hamlyn, L. Brand, M. Shahid, and B.H. Harvey The ampakine, Org 26576, bolsters early spatial reference learning and retrieval in the Morris water maze: a subchronic, dose-ranging study in rats Behav Pharmacol 20 2009 662 667
    • (2009) Behav Pharmacol , vol.20 , pp. 662-667
    • Hamlyn, E.1    Brand, L.2    Shahid, M.3    Harvey, B.H.4
  • 66
    • 34249079802 scopus 로고    scopus 로고
    • Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers
    • E. Wezenberg, R.J. Verkes, G.S. Ruigt, W. Hulstijn, and B.G. Sabbe Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers Neuropsychopharmacology 32 2007 1272 1283
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1272-1283
    • Wezenberg, E.1    Verkes, R.J.2    Ruigt, G.S.3    Hulstijn, W.4    Sabbe, B.G.5
  • 67
    • 33751235837 scopus 로고    scopus 로고
    • The role of acetylcholine in learning and memory
    • M.E. Hasselmo The role of acetylcholine in learning and memory Curr Opin Neurobiol 16 2006 710 715
    • (2006) Curr Opin Neurobiol , vol.16 , pp. 710-715
    • Hasselmo, M.E.1
  • 68
    • 0036890828 scopus 로고    scopus 로고
    • Nicotinic receptor subtypes and cognitive function
    • E.D. Levin Nicotinic receptor subtypes and cognitive function J Neurobiol 53 2002 633 640
    • (2002) J Neurobiol , vol.53 , pp. 633-640
    • Levin, E.D.1
  • 69
    • 32844461888 scopus 로고    scopus 로고
    • Nicotinic effects on cognitive function: Behavioral characterization, pharmacological specification, and anatomic localization
    • E.D. Levin, F.J. McClernon, and A.H. Rezvani Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization Psychopharmacology (Berl) 184 2005 1 17
    • (2005) Psychopharmacology (Berl) , vol.184 , pp. 1-17
    • Levin, E.D.1    McClernon, F.J.2    Rezvani, A.H.3
  • 70
    • 0028998973 scopus 로고
    • Post-injury administration of BIBN 99, a selective muscarinic M2 receptor antagonist, improves cognitive performance following traumatic brain injury in rats
    • B.R. Pike, and R.J. Hamm Post-injury administration of BIBN 99, a selective muscarinic M2 receptor antagonist, improves cognitive performance following traumatic brain injury in rats Brain Res 686 1995 37 43
    • (1995) Brain Res , vol.686 , pp. 37-43
    • Pike, B.R.1    Hamm, R.J.2
  • 71
    • 0028331133 scopus 로고
    • Muscarinic cholinergic receptor binding in rat brain following traumatic brain injury
    • B.G. Lyeth, J.Y. Jiang, T.M. Delahunty, L.L. Phillips, and R.J. Hamm Muscarinic cholinergic receptor binding in rat brain following traumatic brain injury Brain Res 640 1994 240 245
    • (1994) Brain Res , vol.640 , pp. 240-245
    • Lyeth, B.G.1    Jiang, J.Y.2    Delahunty, T.M.3    Phillips, L.L.4    Hamm, R.J.5
  • 72
    • 0028233583 scopus 로고
    • Muscarinic cholinergic receptor binding in rat brain at 15 days following traumatic brain injury
    • J.Y. Jiang, B.G. Lyeth, T.M. Delahunty, L.L. Phillips, and R.J. Hamm Muscarinic cholinergic receptor binding in rat brain at 15 days following traumatic brain injury Brain Res 651 1994 123 128
    • (1994) Brain Res , vol.651 , pp. 123-128
    • Jiang, J.Y.1    Lyeth, B.G.2    Delahunty, T.M.3    Phillips, L.L.4    Hamm, R.J.5
  • 73
    • 0027989726 scopus 로고
    • Traumatic brain injury causes a decrease in M2 muscarinic cholinergic receptor binding in the rat brain
    • M.M. DeAngelis, R.L. Hayes, and B.G. Lyeth Traumatic brain injury causes a decrease in M2 muscarinic cholinergic receptor binding in the rat brain Brain Res 653 1994 39 44
    • (1994) Brain Res , vol.653 , pp. 39-44
    • Deangelis, M.M.1    Hayes, R.L.2    Lyeth, B.G.3
  • 74
    • 0033731647 scopus 로고    scopus 로고
    • Traumatic brain injury reduces hippocampal alpha7 nicotinic cholinergic receptor binding
    • S.L. Verbois, P.G. Sullivan, S.W. Scheff, and J.R. Pauly Traumatic brain injury reduces hippocampal alpha7 nicotinic cholinergic receptor binding J Neurotrauma 17 2000 1001 1011
    • (2000) J Neurotrauma , vol.17 , pp. 1001-1011
    • Verbois, S.L.1    Sullivan, P.G.2    Scheff, S.W.3    Pauly, J.R.4
  • 75
    • 1242272110 scopus 로고    scopus 로고
    • Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: An autoradiographic study in the rat brain
    • E. Tribollet, D. Bertrand, A. Marguerat, and M. Raggenbass Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain Neuroscience 124 2004 405 420
    • (2004) Neuroscience , vol.124 , pp. 405-420
    • Tribollet, E.1    Bertrand, D.2    Marguerat, A.3    Raggenbass, M.4
  • 76
    • 0345131682 scopus 로고    scopus 로고
    • Identification of four classes of brain nicotinic receptors using beta2 mutant mice
    • M. Zoli, C. Lena, M.R. Picciotto, and J.P. Changeux Identification of four classes of brain nicotinic receptors using beta2 mutant mice J Neurosci 18 1998 4461 4472
    • (1998) J Neurosci , vol.18 , pp. 4461-4472
    • Zoli, M.1    Lena, C.2    Picciotto, M.R.3    Changeux, J.P.4
  • 78
    • 0032818891 scopus 로고    scopus 로고
    • An autoradiographic study of the distribution of binding sites for the novel alpha7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain
    • P. Whiteaker, A.R. Davies, M.J. Marks, I.S. Blagbrough, B.V. Potter, and A.J. Wolstenholme An autoradiographic study of the distribution of binding sites for the novel alpha7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain Eur J Neurosci 11 1999 2689 2696
    • (1999) Eur J Neurosci , vol.11 , pp. 2689-2696
    • Whiteaker, P.1    Davies, A.R.2    Marks, M.J.3    Blagbrough, I.S.4    Potter, B.V.5    Wolstenholme, A.J.6
  • 79
    • 0027518923 scopus 로고
    • Molecular cloning, functional properties, and distribution of rat brain alpha 7: A nicotinic cation channel highly permeable to calcium
    • P. Seguela, J. Wadiche, K. Dineley-Miller, J.A. Dani, and J.W. Patrick Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium J Neurosci 13 1993 596 604
    • (1993) J Neurosci , vol.13 , pp. 596-604
    • Seguela, P.1    Wadiche, J.2    Dineley-Miller, K.3    Dani, J.A.4    Patrick, J.W.5
  • 80
    • 0347359010 scopus 로고    scopus 로고
    • 2+ permeability of nicotinic acetylcholine receptors
    • 2+ permeability of nicotinic acetylcholine receptors Cell Calcium 35 2004 1 8
    • (2004) Cell Calcium , vol.35 , pp. 1-8
    • Fucile, S.1
  • 82
    • 0031000154 scopus 로고    scopus 로고
    • Activation of the recombinant human alpha 7 nicotinic acetylcholine receptor significantly raises intracellular free calcium
    • O. Delbono, M. Gopalakrishnan, M. Renganathan, L.M. Monteggia, M.L. Messi, and J.P. Sullivan Activation of the recombinant human alpha 7 nicotinic acetylcholine receptor significantly raises intracellular free calcium J Pharmacol Exp Ther 280 1997 428 438
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 428-438
    • Delbono, O.1    Gopalakrishnan, M.2    Renganathan, M.3    Monteggia, L.M.4    Messi, M.L.5    Sullivan, J.P.6
  • 83
    • 0034602138 scopus 로고    scopus 로고
    • Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons
    • A. Mike, N.G. Castro, and E.X. Albuquerque Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons Brain Res 882 2000 155 168
    • (2000) Brain Res , vol.882 , pp. 155-168
    • Mike, A.1    Castro, N.G.2    Albuquerque, E.X.3
  • 84
    • 0036891571 scopus 로고    scopus 로고
    • Desensitization of neuronal nicotinic receptors
    • M.W. Quick, and R.A. Lester Desensitization of neuronal nicotinic receptors J Neurobiol 53 2002 457 478
    • (2002) J Neurobiol , vol.53 , pp. 457-478
    • Quick, M.W.1    Lester, R.A.2
  • 85
    • 0344089297 scopus 로고    scopus 로고
    • Chronic nicotine treatment attenuates alpha 7 nicotinic receptor deficits following traumatic brain injury
    • S.L. Verbois, S.W. Scheff, and J.R. Pauly Chronic nicotine treatment attenuates alpha 7 nicotinic receptor deficits following traumatic brain injury Neuropharmacology 44 2003 224 233
    • (2003) Neuropharmacology , vol.44 , pp. 224-233
    • Verbois, S.L.1    Scheff, S.W.2    Pauly, J.R.3
  • 86
    • 0037756814 scopus 로고    scopus 로고
    • Chronic intermittent nicotine administration attenuates traumatic brain injury-induced cognitive dysfunction
    • S.L. Verbois, D.M. Hopkins, S.W. Scheff, and J.R. Pauly Chronic intermittent nicotine administration attenuates traumatic brain injury-induced cognitive dysfunction Neuroscience 119 2003 1199 1208
    • (2003) Neuroscience , vol.119 , pp. 1199-1208
    • Verbois, S.L.1    Hopkins, D.M.2    Scheff, S.W.3    Pauly, J.R.4
  • 87
    • 33645972942 scopus 로고    scopus 로고
    • The pathophysiology of traumatic brain injury in alpha7 nicotinic cholinergic receptor knockout mice
    • M.L. Kelso, J.M. Wehner, A.C. Collins, S.W. Scheff, and J.R. Pauly The pathophysiology of traumatic brain injury in alpha7 nicotinic cholinergic receptor knockout mice Brain Res 1083 2006 204 210
    • (2006) Brain Res , vol.1083 , pp. 204-210
    • Kelso, M.L.1    Wehner, J.M.2    Collins, A.C.3    Scheff, S.W.4    Pauly, J.R.5
  • 88
    • 53149111135 scopus 로고    scopus 로고
    • Molecular biology of 5-HT receptors
    • J. Hannon, and D. Hoyer Molecular biology of 5-HT receptors Behav Brain Res 195 2008 198 213
    • (2008) Behav Brain Res , vol.195 , pp. 198-213
    • Hannon, J.1    Hoyer, D.2
  • 89
    • 0031039481 scopus 로고    scopus 로고
    • Extracellular release of serotonin following fluid-percussion brain injury in rats
    • R. Busto, W.D. Dietrich, M.Y. Globus, O. Alonso, and M.D. Ginsberg Extracellular release of serotonin following fluid-percussion brain injury in rats J Neurotrauma 14 1997 35 42
    • (1997) J Neurotrauma , vol.14 , pp. 35-42
    • Busto, R.1    Dietrich, W.D.2    Globus, M.Y.3    Alonso, O.4    Ginsberg, M.D.5
  • 90
    • 8444246333 scopus 로고    scopus 로고
    • Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: In vitro slice and synaptosome studies
    • T.J. Turner, D.J. Mokler, and J.I. Luebke Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: in vitro slice and synaptosome studies Neuroscience 129 2004 703 718
    • (2004) Neuroscience , vol.129 , pp. 703-718
    • Turner, T.J.1    Mokler, D.J.2    Luebke, J.I.3
  • 91
    • 15244339829 scopus 로고    scopus 로고
    • Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist
    • R.L. Papke, H.C. Schiff, B.A. Jack, and N.A. Horenstein Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist Neurosci Lett 378 2005 140 144
    • (2005) Neurosci Lett , vol.378 , pp. 140-144
    • Papke, R.L.1    Schiff, H.C.2    Jack, B.A.3    Horenstein, N.A.4
  • 92
    • 40149106684 scopus 로고    scopus 로고
    • Detrimental effects of tropisetron on permanent ischemic stroke in the rat
    • E. Candelario-Jalil, E. Munoz, and B.L. Fiebich Detrimental effects of tropisetron on permanent ischemic stroke in the rat BMC Neurosci 9 2008 19
    • (2008) BMC Neurosci , vol.9 , pp. 19
    • Candelario-Jalil, E.1    Munoz, E.2    Fiebich, B.L.3
  • 93
    • 54049137689 scopus 로고    scopus 로고
    • International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: Classification on the basis of subunit composition, pharmacology, and function. Update
    • R.W. Olsen, and W. Sieghart International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update Pharmacol Rev 60 2008 243 260
    • (2008) Pharmacol Rev , vol.60 , pp. 243-260
    • Olsen, R.W.1    Sieghart, W.2
  • 94
    • 77954405212 scopus 로고    scopus 로고
    • Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus
    • C.J. Gibson, R.C. Meyer, and R.J. Hamm Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus J Biomed Sci 17 2010 38
    • (2010) J Biomed Sci , vol.17 , pp. 38
    • Gibson, C.J.1    Meyer, R.C.2    Hamm, R.J.3
  • 95
    • 77952552881 scopus 로고    scopus 로고
    • Increase of GABAA receptor-mediated tonic inhibition in dentate granule cells after traumatic brain injury
    • Z. Mtchedlishvili, E. Lepsveridze, H. Xu, E.A. Kharlamov, B. Lu, and K.M. Kelly Increase of GABAA receptor-mediated tonic inhibition in dentate granule cells after traumatic brain injury Neurobiol Dis 38 2010 464 475
    • (2010) Neurobiol Dis , vol.38 , pp. 464-475
    • Mtchedlishvili, Z.1    Lepsveridze, E.2    Xu, H.3    Kharlamov, E.A.4    Lu, B.5    Kelly, K.M.6
  • 96
    • 77950608137 scopus 로고    scopus 로고
    • Flumazenil administration attenuates cognitive impairment in immature rats after controlled cortical impact
    • P.G. Ochalski, W. Fellows-Mayle, L.B. Hsieh, R. Srinivas, D.O. Okonkwo, and C.E. Dixon Flumazenil administration attenuates cognitive impairment in immature rats after controlled cortical impact J Neurotrauma 27 2010 647 651
    • (2010) J Neurotrauma , vol.27 , pp. 647-651
    • Ochalski, P.G.1    Fellows-Mayle, W.2    Hsieh, L.B.3    Srinivas, R.4    Okonkwo, D.O.5    Dixon, C.E.6
  • 97
    • 78650878107 scopus 로고    scopus 로고
    • NINDS Spasticity Information Page [Internet] Bethesda MD: National Institutes of Health, National Institute of Neurological Disorders and Stroke, Office of Communications and Public Liason; [Updated 06/25/2010]
    • NINDS Spasticity Information Page [Internet] Bethesda MD: National Institutes of Health, National Institute of Neurological Disorders and Stroke, Office of Communications and Public Liason; [Updated 06/25/2010]; http://www.ninds.nih.gov/disorders/spasticity/spasticity.htm
  • 99
    • 18044396542 scopus 로고    scopus 로고
    • GABAB receptor antagonist SGS742 improves spatial memory and reduces protein binding to the cAMP response element (CRE) in the hippocampus
    • K.A. Helm, R.P. Haberman, S.L. Dean, E.C. Hoyt, T. Melcher, and P.K. Lund GABAB receptor antagonist SGS742 improves spatial memory and reduces protein binding to the cAMP response element (CRE) in the hippocampus Neuropharmacology 48 2005 956 964
    • (2005) Neuropharmacology , vol.48 , pp. 956-964
    • Helm, K.A.1    Haberman, R.P.2    Dean, S.L.3    Hoyt, E.C.4    Melcher, T.5    Lund, P.K.6
  • 101
    • 0027240525 scopus 로고
    • Concussive brain injury is associated with a prolonged accumulation of calcium: A 45Ca autoradiographic study
    • I. Fineman, D.A. Hovda, M. Smith, A. Yoshino, and D.P. Becker Concussive brain injury is associated with a prolonged accumulation of calcium: a 45Ca autoradiographic study Brain Res 624 1993 94 102
    • (1993) Brain Res , vol.624 , pp. 94-102
    • Fineman, I.1    Hovda, D.A.2    Smith, M.3    Yoshino, A.4    Becker, D.P.5
  • 102
    • 0030047543 scopus 로고    scopus 로고
    • Calcium movements in traumatic brain injury: The role of glutamate receptor-operated ion channels
    • P. Nilsson, H. Laursen, L. Hillered, and A.J. Hansen Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels J Cereb Blood Flow Metab 16 1996 262 270
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 262-270
    • Nilsson, P.1    Laursen, H.2    Hillered, L.3    Hansen, A.J.4
  • 104
    • 34249092704 scopus 로고    scopus 로고
    • Calcium and neurodegeneration
    • M.P. Mattson Calcium and neurodegeneration Aging Cell 6 2007 337 350
    • (2007) Aging Cell , vol.6 , pp. 337-350
    • Mattson, M.P.1
  • 105
    • 33747137966 scopus 로고    scopus 로고
    • Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: Implications for neuroprotective therapy
    • I.N. Singh, P.G. Sullivan, Y. Deng, L.H. Mbye, and E.D. Hall Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy J Cereb Blood Flow Metab 26 2006 1407 1418
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1407-1418
    • Singh, I.N.1    Sullivan, P.G.2    Deng, Y.3    Mbye, L.H.4    Hall, E.D.5
  • 107
    • 33750737707 scopus 로고    scopus 로고
    • Effect of nimodipine on outcome in patients with traumatic subarachnoid haemorrhage: A systematic review
    • M.D. Vergouwen, M. Vermeulen, and Y.B. Roos Effect of nimodipine on outcome in patients with traumatic subarachnoid haemorrhage: a systematic review Lancet Neurol 5 2006 1029 1032
    • (2006) Lancet Neurol , vol.5 , pp. 1029-1032
    • Vergouwen, M.D.1    Vermeulen, M.2    Roos, Y.B.3
  • 108
    • 58749098750 scopus 로고    scopus 로고
    • Nimodipine can improve cerebral metabolism and outcome in patients with severe head trauma
    • A. Aslan, M. Gurelik, M. Cemek, H.M. Goksel, and M.E. Buyukokuroglu Nimodipine can improve cerebral metabolism and outcome in patients with severe head trauma Pharmacol Res 59 2009 120 124
    • (2009) Pharmacol Res , vol.59 , pp. 120-124
    • Aslan, A.1    Gurelik, M.2    Cemek, M.3    Goksel, H.M.4    Buyukokuroglu, M.E.5
  • 109
    • 57649112668 scopus 로고    scopus 로고
    • Intra-arterial calcium channel blocker infusion for treatment of severe vasospasm in traumatic brain injury: Case report
    • D.J. Lee, P. Moftakhar, T.C. Glenn, P.M. Vespa, and N.A. Martin Intra-arterial calcium channel blocker infusion for treatment of severe vasospasm in traumatic brain injury: case report Neurosurgery 63 2008 E1004 E1006 discussion E1006
    • (2008) Neurosurgery , vol.63
    • Lee, D.J.1    Moftakhar, P.2    Glenn, T.C.3    Vespa, P.M.4    Martin, N.A.5
  • 110
    • 57749093019 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders
    • K.R. Byrnes, D.J. Loane, and A.I. Faden Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders Neurotherapeutics 6 2009 94 107
    • (2009) Neurotherapeutics , vol.6 , pp. 94-107
    • Byrnes, K.R.1    Loane, D.J.2    Faden, A.I.3
  • 111
    • 0028973275 scopus 로고
    • Metabotropic glutamate antagonist, MCPG, treatment of traumatic brain injury in rats
    • Q.Z. Gong, T.M. Delahunty, R.J. Hamm, and B.G. Lyeth Metabotropic glutamate antagonist, MCPG, treatment of traumatic brain injury in rats Brain Res 700 1995 299 302
    • (1995) Brain Res , vol.700 , pp. 299-302
    • Gong, Q.Z.1    Delahunty, T.M.2    Hamm, R.J.3    Lyeth, B.G.4
  • 112
    • 0029832301 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury
    • A. Mukhin, L. Fan, and A.I. Faden Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury J Neurosci 16 1996 6012 6020
    • (1996) J Neurosci , vol.16 , pp. 6012-6020
    • Mukhin, A.1    Fan, L.2    Faden, A.I.3
  • 113
    • 0033011390 scopus 로고    scopus 로고
    • Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury
    • J.W. Allen, S.A. Ivanova, L. Fan, M.G. Espey, A.S. Basile, and A.I. Faden Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury J Pharmacol Exp Ther 290 1999 112 120
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 112-120
    • Allen, J.W.1    Ivanova, S.A.2    Fan, L.3    Espey, M.G.4    Basile, A.S.5    Faden, A.I.6
  • 114
    • 0031407416 scopus 로고    scopus 로고
    • Neuroprotective effects of group III mGluR in traumatic neuronal injury
    • A.I. Faden, S.A. Ivanova, A.G. Yakovlev, and A.G. Mukhin Neuroprotective effects of group III mGluR in traumatic neuronal injury J Neurotrauma 14 1997 885 895
    • (1997) J Neurotrauma , vol.14 , pp. 885-895
    • Faden, A.I.1    Ivanova, S.A.2    Yakovlev, A.G.3    Mukhin, A.G.4
  • 116
    • 8644225788 scopus 로고    scopus 로고
    • Time dependent alterations in dopamine tissue levels and metabolism after experimental traumatic brain injury in rats
    • J.L. Massucci, A.E. Kline, X. Ma, R.D. Zafonte, and C.E. Dixon Time dependent alterations in dopamine tissue levels and metabolism after experimental traumatic brain injury in rats Neurosci Lett 372 2004 127 131
    • (2004) Neurosci Lett , vol.372 , pp. 127-131
    • Massucci, J.L.1    Kline, A.E.2    Ma, X.3    Zafonte, R.D.4    Dixon, C.E.5
  • 118
    • 33746696008 scopus 로고    scopus 로고
    • Enhanced catecholamine synthesis in the prefrontal cortex after traumatic brain injury: Implications for prefrontal dysfunction
    • N. Kobori, G.L. Clifton, and P.K. Dash Enhanced catecholamine synthesis in the prefrontal cortex after traumatic brain injury: implications for prefrontal dysfunction J Neurotrauma 23 2006 1094 1102
    • (2006) J Neurotrauma , vol.23 , pp. 1094-1102
    • Kobori, N.1    Clifton, G.L.2    Dash, P.K.3
  • 119
    • 33846355347 scopus 로고    scopus 로고
    • Delayed increase of tyrosine hydroxylase expression in rat nigrostriatal system after traumatic brain injury
    • H.Q. Yan, X. Ma, X. Chen, Y. Li, L. Shao, and C.E. Dixon Delayed increase of tyrosine hydroxylase expression in rat nigrostriatal system after traumatic brain injury Brain Res 1134 2007 171 179
    • (2007) Brain Res , vol.1134 , pp. 171-179
    • Yan, H.Q.1    Ma, X.2    Chen, X.3    Li, Y.4    Shao, L.5    Dixon, C.E.6
  • 120
    • 67649479358 scopus 로고    scopus 로고
    • Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis
    • J.W. Bales, A.K. Wagner, A.E. Kline, and C.E. Dixon Persistent cognitive dysfunction after traumatic brain injury: a dopamine hypothesis Neurosci Biobehav Rev 33 2009 981 1003
    • (2009) Neurosci Biobehav Rev , vol.33 , pp. 981-1003
    • Bales, J.W.1    Wagner, A.K.2    Kline, A.E.3    Dixon, C.E.4
  • 121
    • 77953636468 scopus 로고    scopus 로고
    • Attention-deficit/hyperactivity disorder and the dopaminergic hypotheses
    • J.P. Genro, C. Kieling, L.A. Rohde, and M.H. Hutz Attention-deficit/ hyperactivity disorder and the dopaminergic hypotheses Expert Rev Neurother 10 2010 587 601
    • (2010) Expert Rev Neurother , vol.10 , pp. 587-601
    • Genro, J.P.1    Kieling, C.2    Rohde, L.A.3    Hutz, M.H.4
  • 122
    • 53149107873 scopus 로고    scopus 로고
    • Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain
    • L. Saenz del Burgo, R. Cortes, G. Mengod, J. Zarate, E. Echevarria, and J. Salles Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain J Comp Neurol 510 2008 581 606
    • (2008) J Comp Neurol , vol.510 , pp. 581-606
    • Saenz Del Burgo, L.1    Cortes, R.2    Mengod, G.3    Zarate, J.4    Echevarria, E.5    Salles, J.6
  • 123
    • 0030929885 scopus 로고    scopus 로고
    • Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons
    • M.U. Ehrengruber, C.A. Doupnik, Y. Xu, J. Garvey, M.C. Jasek, and H.A. Lester Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons Proc Natl Acad Sci USA 94 1997 7070 7075
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 7070-7075
    • Ehrengruber, M.U.1    Doupnik, C.A.2    Xu, Y.3    Garvey, J.4    Jasek, M.C.5    Lester, H.A.6
  • 124
    • 0035959941 scopus 로고    scopus 로고
    • The selective 5-HT(1A) receptor agonist repinotan HCl attenuates histopathology and spatial learning deficits following traumatic brain injury in rats
    • A.E. Kline, J. Yu, E. Horvath, D.W. Marion, and C.E. Dixon The selective 5-HT(1A) receptor agonist repinotan HCl attenuates histopathology and spatial learning deficits following traumatic brain injury in rats Neuroscience 106 2001 547 555
    • (2001) Neuroscience , vol.106 , pp. 547-555
    • Kline, A.E.1    Yu, J.2    Horvath, E.3    Marion, D.W.4    Dixon, C.E.5
  • 125
    • 33947194212 scopus 로고    scopus 로고
    • The neurobehavioral benefit conferred by a single systemic administration of 8-OH-DPAT after brain trauma is confined to a narrow therapeutic window
    • J.P. Cheng, H.A. Aslam, A.N. Hoffman, R.D. Zafonte, and A.E. Kline The neurobehavioral benefit conferred by a single systemic administration of 8-OH-DPAT after brain trauma is confined to a narrow therapeutic window Neurosci Lett 416 2007 165 168
    • (2007) Neurosci Lett , vol.416 , pp. 165-168
    • Cheng, J.P.1    Aslam, H.A.2    Hoffman, A.N.3    Zafonte, R.D.4    Kline, A.E.5
  • 126
    • 0036120181 scopus 로고    scopus 로고
    • Effects of fluoxetine on the 5-HT1A receptor and recovery of cognitive function after traumatic brain injury in rats
    • M.S. Wilson, and R.J. Hamm Effects of fluoxetine on the 5-HT1A receptor and recovery of cognitive function after traumatic brain injury in rats Am J Phys Med Rehabil 81 2002 364 372
    • (2002) Am J Phys Med Rehabil , vol.81 , pp. 364-372
    • Wilson, M.S.1    Hamm, R.J.2
  • 127
    • 50049135342 scopus 로고    scopus 로고
    • A delayed and chronic treatment regimen with the 5-HT1A receptor agonist 8-OH-DPAT after cortical impact injury facilitates motor recovery and acquisition of spatial learning
    • J.P. Cheng, A.N. Hoffman, R.D. Zafonte, and A.E. Kline A delayed and chronic treatment regimen with the 5-HT1A receptor agonist 8-OH-DPAT after cortical impact injury facilitates motor recovery and acquisition of spatial learning Behav Brain Res 194 2008 79 85
    • (2008) Behav Brain Res , vol.194 , pp. 79-85
    • Cheng, J.P.1    Hoffman, A.N.2    Zafonte, R.D.3    Kline, A.E.4
  • 128
    • 75449095711 scopus 로고    scopus 로고
    • Treatment for depression after traumatic brain injury: A systematic review
    • J.R. Fann, T. Hart, and K.G. Schomer Treatment for depression after traumatic brain injury: a systematic review J Neurotrauma 26 2009 2383 2402
    • (2009) J Neurotrauma , vol.26 , pp. 2383-2402
    • Fann, J.R.1    Hart, T.2    Schomer, K.G.3
  • 129
    • 53249105425 scopus 로고    scopus 로고
    • Neurobehavioral management of traumatic brain injury in the critical care setting
    • D.B. Arciniegas, and T.W. McAllister Neurobehavioral management of traumatic brain injury in the critical care setting Crit Care Clin 24 2008 737 765
    • (2008) Crit Care Clin , vol.24 , pp. 737-765
    • Arciniegas, D.B.1    McAllister, T.W.2
  • 130
    • 34547800263 scopus 로고    scopus 로고
    • Guidelines for the management of severe traumatic brain injury. XI. Anesthetics, analgesics, and sedatives
    • S.L. Bratton, R.M. Chestnut, J. Ghajar, F.F. McConnell Hammond, O.A. Harris, and R. Hartl Guidelines for the management of severe traumatic brain injury. XI. Anesthetics, analgesics, and sedatives J Neurotrauma 24 Suppl. 1 2007 S71 S76
    • (2007) J Neurotrauma , vol.24 , Issue.SUPPL. 1
    • Bratton, S.L.1    Chestnut, R.M.2    Ghajar, J.3    McConnell Hammond, F.F.4    Harris, O.A.5    Hartl, R.6
  • 131
    • 31944438278 scopus 로고    scopus 로고
    • Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats
    • K.D. Statler, H. Alexander, V. Vagni, C.E. Dixon, R.S. Clark, and L. Jenkins Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats J Neurotrauma 23 2006 97 108
    • (2006) J Neurotrauma , vol.23 , pp. 97-108
    • Statler, K.D.1    Alexander, H.2    Vagni, V.3    Dixon, C.E.4    Clark, R.S.5    Jenkins, L.6
  • 132
    • 31344451953 scopus 로고    scopus 로고
    • Morphine protects for head trauma induced cognitive deficits in mice
    • O. Zohar, V. Getslev, A.L. Miller, S. Schreiber, and C.G. Pick Morphine protects for head trauma induced cognitive deficits in mice Neurosci Lett 394 2006 239 242
    • (2006) Neurosci Lett , vol.394 , pp. 239-242
    • Zohar, O.1    Getslev, V.2    Miller, A.L.3    Schreiber, S.4    Pick, C.G.5
  • 133
    • 70349674406 scopus 로고    scopus 로고
    • Effect of acute inflammatory brain injury on accumulation of morphine and morphine 3- and 6-glucuronide in the human brain
    • D.J. Roberts, K.B. Goralski, K.W. Renton, L.C. Julien, A.M. Webber, and L. Sleno Effect of acute inflammatory brain injury on accumulation of morphine and morphine 3- and 6-glucuronide in the human brain Crit Care Med 37 2009 2767 2774
    • (2009) Crit Care Med , vol.37 , pp. 2767-2774
    • Roberts, D.J.1    Goralski, K.B.2    Renton, K.W.3    Julien, L.C.4    Webber, A.M.5    Sleno, L.6
  • 134
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
    • A.N. Hata, and R.M. Breyer Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation Pharmacol Ther 103 2004 147 166
    • (2004) Pharmacol Ther , vol.103 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 135
    • 27644451820 scopus 로고    scopus 로고
    • Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: Accumulation in Purkinje cells of the cerebellum
    • E. Candelario-Jalil, H. Slawik, I. Ridelis, A. Waschbisch, R.S. Akundi, and M. Hull Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: accumulation in Purkinje cells of the cerebellum J Mol Neurosci 27 2005 303 310
    • (2005) J Mol Neurosci , vol.27 , pp. 303-310
    • Candelario-Jalil, E.1    Slawik, H.2    Ridelis, I.3    Waschbisch, A.4    Akundi, R.S.5    Hull, M.6
  • 136
    • 32244432739 scopus 로고    scopus 로고
    • Prostaglandin E2 EP1 receptors: Downstream effectors of COX-2 neurotoxicity
    • T. Kawano, J. Anrather, P. Zhou, L. Park, G. Wang, and K.A. Frys Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity Nat Med 12 2006 225 229
    • (2006) Nat Med , vol.12 , pp. 225-229
    • Kawano, T.1    Anrather, J.2    Zhou, P.3    Park, L.4    Wang, G.5    Frys, K.A.6
  • 137
    • 39249084592 scopus 로고    scopus 로고
    • Neuroprotection by PGE2 receptor EP1 inhibition involves the PTEN/AKT pathway
    • P. Zhou, L. Qian, T. Chou, and C. Iadecola Neuroprotection by PGE2 receptor EP1 inhibition involves the PTEN/AKT pathway Neurobiol Dis 29 2008 543 551
    • (2008) Neurobiol Dis , vol.29 , pp. 543-551
    • Zhou, P.1    Qian, L.2    Chou, T.3    Iadecola, C.4
  • 138
    • 77953807028 scopus 로고    scopus 로고
    • Prostanoid EP(1) receptor antagonist reduces blood-brain barrier leakage after cerebral ischemia
    • K.I. Fukumoto, N. Takagi, R. Yamamoto, Y. Moriyama, S. Takeo, and K. Tanonaka Prostanoid EP(1) receptor antagonist reduces blood-brain barrier leakage after cerebral ischemia Eur J Pharmacol 640 2010 82 86
    • (2010) Eur J Pharmacol , vol.640 , pp. 82-86
    • Fukumoto, K.I.1    Takagi, N.2    Yamamoto, R.3    Moriyama, Y.4    Takeo, S.5    Tanonaka, K.6
  • 139
  • 140
    • 0842322738 scopus 로고    scopus 로고
    • Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia
    • L. McCullough, L. Wu, N. Haughey, X. Liang, T. Hand, and Q. Wang Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia J Neurosci 24 2004 257 268
    • (2004) J Neurosci , vol.24 , pp. 257-268
    • McCullough, L.1    Wu, L.2    Haughey, N.3    Liang, X.4    Hand, T.5    Wang, Q.6
  • 141
    • 0032902146 scopus 로고    scopus 로고
    • Prostaglandin e receptor subtypes in cultured rat microglia and their role in reducing lipopolysaccharide-induced interleukin-1beta production
    • A.O. Caggiano, and R.P. Kraig Prostaglandin E receptor subtypes in cultured rat microglia and their role in reducing lipopolysaccharide-induced interleukin-1beta production J Neurochem 72 1999 565 575
    • (1999) J Neurochem , vol.72 , pp. 565-575
    • Caggiano, A.O.1    Kraig, R.P.2
  • 142
    • 58149387068 scopus 로고    scopus 로고
    • Monomeric IgG is neuroprotective via enhancing microglial recycling endocytosis and TNF-alpha
    • R.E. Hulse, W.G. Swenson, P.E. Kunkler, D.M. White, and R.P. Kraig Monomeric IgG is neuroprotective via enhancing microglial recycling endocytosis and TNF-alpha J Neurosci 28 2008 12199 12211
    • (2008) J Neurosci , vol.28 , pp. 12199-12211
    • Hulse, R.E.1    Swenson, W.G.2    Kunkler, P.E.3    White, D.M.4    Kraig, R.P.5
  • 143
    • 27444436866 scopus 로고    scopus 로고
    • Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity
    • F.S. Shie, K.S. Montine, R.M. Breyer, and T.J. Montine Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity Glia 52 2005 70 77
    • (2005) Glia , vol.52 , pp. 70-77
    • Shie, F.S.1    Montine, K.S.2    Breyer, R.M.3    Montine, T.J.4
  • 144
    • 33845922141 scopus 로고    scopus 로고
    • Stimulation of prostaglandin EP2 receptors prevents NMDA-induced excitotoxicity
    • A.S. Ahmad, H. Zhuang, V. Echeverria, and S. Dore Stimulation of prostaglandin EP2 receptors prevents NMDA-induced excitotoxicity J Neurotrauma 23 2006 1895 1903
    • (2006) J Neurotrauma , vol.23 , pp. 1895-1903
    • Ahmad, A.S.1    Zhuang, H.2    Echeverria, V.3    Dore, S.4
  • 145
    • 76649098560 scopus 로고    scopus 로고
    • Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor
    • J. Jiang, T. Ganesh, Y. Du, P. Thepchatri, A. Rojas, and I. Lewis Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor Proc Natl Acad Sci USA 107 2010 2307 2312
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2307-2312
    • Jiang, J.1    Ganesh, T.2    Du, Y.3    Thepchatri, P.4    Rojas, A.5    Lewis, I.6
  • 146
    • 0034606558 scopus 로고    scopus 로고
    • Distribution of the EP3 prostaglandin E(2) receptor subtype in the rat brain: Relationship to sites of interleukin-1-induced cellular responsiveness
    • M. Ek, C. Arias, P. Sawchenko, and A. Ericsson-Dahlstrand Distribution of the EP3 prostaglandin E(2) receptor subtype in the rat brain: relationship to sites of interleukin-1-induced cellular responsiveness J Comp Neurol 428 2000 5 20
    • (2000) J Comp Neurol , vol.428 , pp. 5-20
    • Ek, M.1    Arias, C.2    Sawchenko, P.3    Ericsson-Dahlstrand, A.4
  • 147
    • 62549089661 scopus 로고    scopus 로고
    • Reduced acute brain injury in PGE2 EP3 receptor-deficient mice after cerebral ischemia
    • S. Saleem, Y.T. Kim, T. Maruyama, S. Narumiya, and S. Dore Reduced acute brain injury in PGE2 EP3 receptor-deficient mice after cerebral ischemia J Neuroimmunol 208 2009 87 93
    • (2009) J Neuroimmunol , vol.208 , pp. 87-93
    • Saleem, S.1    Kim, Y.T.2    Maruyama, T.3    Narumiya, S.4    Dore, S.5
  • 148
    • 29044431515 scopus 로고    scopus 로고
    • Prostaglandin EP4 receptor agonist protects against acute neurotoxicity
    • A.S. Ahmad, M. Ahmad, A.J. de Brum-Fernandes, and S. Dore Prostaglandin EP4 receptor agonist protects against acute neurotoxicity Brain Res 1066 2005 71 77
    • (2005) Brain Res , vol.1066 , pp. 71-77
    • Ahmad, A.S.1    Ahmad, M.2    De Brum-Fernandes, A.J.3    Dore, S.4
  • 149
    • 77953638394 scopus 로고    scopus 로고
    • The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity
    • J. Shi, J. Johansson, N.S. Woodling, Q. Wang, T.J. Montine, and K. Andreasson The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity J Immunol 184 2010 7207 7218
    • (2010) J Immunol , vol.184 , pp. 7207-7218
    • Shi, J.1    Johansson, J.2    Woodling, N.S.3    Wang, Q.4    Montine, T.J.5    Andreasson, K.6
  • 150
    • 20244378089 scopus 로고    scopus 로고
    • Cerebrospinal fluid concentrations of anti-inflammatory mediators in early-phase severe traumatic brain injury
    • T. Shiozaki, T. Hayakata, O. Tasaki, H. Hosotubo, K. Fuijita, and T. Mouri Cerebrospinal fluid concentrations of anti-inflammatory mediators in early-phase severe traumatic brain injury Shock 23 2005 406 410
    • (2005) Shock , vol.23 , pp. 406-410
    • Shiozaki, T.1    Hayakata, T.2    Tasaki, O.3    Hosotubo, H.4    Fuijita, K.5    Mouri, T.6
  • 151
    • 77950625842 scopus 로고    scopus 로고
    • In situ detection of inflammatory mediators in post mortem human brain tissue after traumatic injury
    • T. Frugier, M.C. Morganti-Kossmann, D. O'Reilly, and C.A. McLean In situ detection of inflammatory mediators in post mortem human brain tissue after traumatic injury J Neurotrauma 27 2010 497 507
    • (2010) J Neurotrauma , vol.27 , pp. 497-507
    • Frugier, T.1    Morganti-Kossmann, M.C.2    O'Reilly, D.3    McLean, C.A.4
  • 152
    • 69249208444 scopus 로고    scopus 로고
    • Minocycline effects on cerebral edema: Relations with inflammatory and oxidative stress markers following traumatic brain injury in mice
    • S. Homsi, F. Federico, N. Croci, B. Palmier, M. Plotkine, and C. Marchand-Leroux Minocycline effects on cerebral edema: relations with inflammatory and oxidative stress markers following traumatic brain injury in mice Brain Res 1291 2009 122 132
    • (2009) Brain Res , vol.1291 , pp. 122-132
    • Homsi, S.1    Federico, F.2    Croci, N.3    Palmier, B.4    Plotkine, M.5    Marchand-Leroux, C.6
  • 153
    • 68249103676 scopus 로고    scopus 로고
    • Neutralization of interleukin-1beta modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice
    • F. Clausen, A. Hanell, M. Bjork, L. Hillered, A.K. Mir, and H. Gram Neutralization of interleukin-1beta modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice Eur J Neurosci 30 2009 385 396
    • (2009) Eur J Neurosci , vol.30 , pp. 385-396
    • Clausen, F.1    Hanell, A.2    Bjork, M.3    Hillered, L.4    Mir, A.K.5    Gram, H.6
  • 154
    • 68149160611 scopus 로고    scopus 로고
    • Nanoparticle-mediated delivery of superoxide dismutase to the brain: An effective strategy to reduce ischemia-reperfusion injury
    • M.K. Reddy, and V. Labhasetwar Nanoparticle-mediated delivery of superoxide dismutase to the brain: an effective strategy to reduce ischemia-reperfusion injury FASEB J 23 2009 1384 1395
    • (2009) FASEB J , vol.23 , pp. 1384-1395
    • Reddy, M.K.1    Labhasetwar, V.2
  • 157
    • 34547601983 scopus 로고    scopus 로고
    • Nanomedicine in the diagnosis and therapy of neurodegenerative disorders
    • A.V. Kabanov, and H.E. Gendelman Nanomedicine in the diagnosis and therapy of neurodegenerative disorders Prog Polym Sci 32 2007 1054 1082
    • (2007) Prog Polym Sci , vol.32 , pp. 1054-1082
    • Kabanov, A.V.1    Gendelman, H.E.2
  • 158
    • 61849137768 scopus 로고    scopus 로고
    • Direct inhibition of the mitochondrial permeability transition pore: A possible mechanism for better neuroprotective effects of allopregnanolone over progesterone
    • I. Sayeed, S. Parvez, B. Wali, D. Siemen, and D.G. Stein Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism for better neuroprotective effects of allopregnanolone over progesterone Brain Res 1263 2009 165 173
    • (2009) Brain Res , vol.1263 , pp. 165-173
    • Sayeed, I.1    Parvez, S.2    Wali, B.3    Siemen, D.4    Stein, D.G.5
  • 159
    • 67849097743 scopus 로고    scopus 로고
    • Progesterone as a neuroprotective factor in traumatic and ischemic brain injury
    • I. Sayeed, and D.G. Stein Progesterone as a neuroprotective factor in traumatic and ischemic brain injury Prog Brain Res 175 2009 219 237
    • (2009) Prog Brain Res , vol.175 , pp. 219-237
    • Sayeed, I.1    Stein, D.G.2
  • 160
    • 46349091964 scopus 로고    scopus 로고
    • Efficacy of progesterone following a moderate unilateral cortical contusion injury
    • L.K. Gilmer, K.N. Roberts, and S.W. Scheff Efficacy of progesterone following a moderate unilateral cortical contusion injury J Neurotrauma 25 2008 593 602
    • (2008) J Neurotrauma , vol.25 , pp. 593-602
    • Gilmer, L.K.1    Roberts, K.N.2    Scheff, S.W.3
  • 162
    • 43249131666 scopus 로고    scopus 로고
    • Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: A randomized controlled trial
    • G. Xiao, J. Wei, W. Yan, W. Wang, and Z. Lu Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial Crit Care 12 2008 R61
    • (2008) Crit Care , vol.12 , pp. 61
    • Xiao, G.1    Wei, J.2    Yan, W.3    Wang, W.4    Lu, Z.5
  • 163
    • 0038070602 scopus 로고    scopus 로고
    • Immunolocalization of estrogen receptor beta in the mouse brain: Comparison with estrogen receptor alpha
    • S.W. Mitra, E. Hoskin, J. Yudkovitz, L. Pear, H.A. Wilkinson, and S. Hayashi Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha Endocrinology 144 2003 2055 2067
    • (2003) Endocrinology , vol.144 , pp. 2055-2067
    • Mitra, S.W.1    Hoskin, E.2    Yudkovitz, J.3    Pear, L.4    Wilkinson, H.A.5    Hayashi, S.6
  • 164
    • 73349089967 scopus 로고    scopus 로고
    • Premarin stimulates estrogen receptor-alpha to protect against traumatic brain injury in male rats
    • S.H. Chen, C.Y. Chang, H.K. Chang, W.C. Chen, M.T. Lin, and J.J. Wang Premarin stimulates estrogen receptor-alpha to protect against traumatic brain injury in male rats Crit Care Med 37 2009 3097 3106
    • (2009) Crit Care Med , vol.37 , pp. 3097-3106
    • Chen, S.H.1    Chang, C.Y.2    Chang, H.K.3    Chen, W.C.4    Lin, M.T.5    Wang, J.J.6
  • 166
    • 77952043259 scopus 로고    scopus 로고
    • Aquaporin-1-mediated cerebral edema following traumatic brain injury: Effects of acidosis and corticosteroid administration
    • N.D. Tran, S. Kim, H.K. Vincent, A. Rodriguez, D.R. Hinton, and M.R. Bullock Aquaporin-1-mediated cerebral edema following traumatic brain injury: effects of acidosis and corticosteroid administration J Neurosurg 112 2010 1095 1104
    • (2010) J Neurosurg , vol.112 , pp. 1095-1104
    • Tran, N.D.1    Kim, S.2    Vincent, H.K.3    Rodriguez, A.4    Hinton, D.R.5    Bullock, M.R.6
  • 167
    • 34249908100 scopus 로고    scopus 로고
    • Dexamethasone attenuates early expression of three molecules associated with microglia/macrophages activation following rat traumatic brain injury
    • Z. Zhang, M. Artelt, M. Burnet, and H.J. Schluesener Dexamethasone attenuates early expression of three molecules associated with microglia/macrophages activation following rat traumatic brain injury Acta Neuropathol 113 2007 675 682
    • (2007) Acta Neuropathol , vol.113 , pp. 675-682
    • Zhang, Z.1    Artelt, M.2    Burnet, M.3    Schluesener, H.J.4
  • 168
    • 60749105369 scopus 로고    scopus 로고
    • Glucocorticoids aggravate retrograde memory deficiency associated with traumatic brain injury in rats
    • X. Chen, K.L. Zhang, S.Y. Yang, J.F. Dong, and J.N. Zhang Glucocorticoids aggravate retrograde memory deficiency associated with traumatic brain injury in rats J Neurotrauma 26 2009 253 260
    • (2009) J Neurotrauma , vol.26 , pp. 253-260
    • Chen, X.1    Zhang, K.L.2    Yang, S.Y.3    Dong, J.F.4    Zhang, J.N.5
  • 169
    • 20444399890 scopus 로고    scopus 로고
    • Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months
    • P. Edwards, M. Arango, L. Balica, R. Cottingham, H. El-Sayed, and B. Farrell Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months Lancet 365 2005 1957 1959
    • (2005) Lancet , vol.365 , pp. 1957-1959
    • Edwards, P.1    Arango, M.2    Balica, L.3    Cottingham, R.4    El-Sayed, H.5    Farrell, B.6
  • 171
    • 57149141676 scopus 로고    scopus 로고
    • Synthesis and evaluation of a well-defined HPMA copolymer-dexamethasone conjugate for effective treatment of rheumatoid arthritis
    • X.M. Liu, L.D. Quan, J. Tian, Y. Alnouti, K. Fu, and G.M. Thiele Synthesis and evaluation of a well-defined HPMA copolymer-dexamethasone conjugate for effective treatment of rheumatoid arthritis Pharm Res 25 2008 2910 2919
    • (2008) Pharm Res , vol.25 , pp. 2910-2919
    • Liu, X.M.1    Quan, L.D.2    Tian, J.3    Alnouti, Y.4    Fu, K.5    Thiele, G.M.6
  • 172
    • 33847214593 scopus 로고    scopus 로고
    • Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis
    • D. Wang, S.C. Miller, X.M. Liu, B. Anderson, X.S. Wang, and S.R. Goldring Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis Arthritis Res Ther 9 2007 R2
    • (2007) Arthritis Res Ther , vol.9 , pp. 2
    • Wang, D.1    Miller, S.C.2    Liu, X.M.3    Anderson, B.4    Wang, X.S.5    Goldring, S.R.6
  • 173
    • 0023432351 scopus 로고
    • Effects of traumatic brain injury on cerebral high-energy phosphates and pH: A 31P magnetic resonance spectroscopy study
    • R. Vink, T.K. McIntosh, M.W. Weiner, and A.I. Faden Effects of traumatic brain injury on cerebral high-energy phosphates and pH: a 31P magnetic resonance spectroscopy study J Cereb Blood Flow Metab 7 1987 563 571
    • (1987) J Cereb Blood Flow Metab , vol.7 , pp. 563-571
    • Vink, R.1    McIntosh, T.K.2    Weiner, M.W.3    Faden, A.I.4
  • 174
    • 0023617041 scopus 로고
    • Traumatic brain injury in the rat: Alterations in brain lactate and pH as characterized by 1H and 31P nuclear magnetic resonance
    • T.K. McIntosh, A.I. Faden, M.R. Bendall, and R. Vink Traumatic brain injury in the rat: alterations in brain lactate and pH as characterized by 1H and 31P nuclear magnetic resonance J Neurochem 49 1987 1530 1540
    • (1987) J Neurochem , vol.49 , pp. 1530-1540
    • McIntosh, T.K.1    Faden, A.I.2    Bendall, M.R.3    Vink, R.4
  • 175
    • 0345118108 scopus 로고    scopus 로고
    • Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS
    • S. Moreno, S. Farioli-Vecchioli, and M.P. Ceru Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS Neuroscience 123 2004 131 145
    • (2004) Neuroscience , vol.123 , pp. 131-145
    • Moreno, S.1    Farioli-Vecchioli, S.2    Ceru, M.P.3
  • 176
    • 56049113451 scopus 로고    scopus 로고
    • PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms
    • J.H. Yi, S.W. Park, N. Brooks, B.T. Lang, and R. Vemuganti PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms Brain Res 1244 2008 164 172
    • (2008) Brain Res , vol.1244 , pp. 164-172
    • Yi, J.H.1    Park, S.W.2    Brooks, N.3    Lang, B.T.4    Vemuganti, R.5
  • 177
    • 0038720453 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment
    • D. Deplanque, P. Gele, O. Petrault, I. Six, C. Furman, and M. Bouly Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment J Neurosci 23 2003 6264 6271
    • (2003) J Neurosci , vol.23 , pp. 6264-6271
    • Deplanque, D.1    Gele, P.2    Petrault, O.3    Six, I.4    Furman, C.5    Bouly, M.6
  • 178
    • 27244452751 scopus 로고    scopus 로고
    • Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, exerts neuroprotective effects in traumatic brain injury
    • V.C. Besson, X.R. Chen, M. Plotkine, and C. Marchand-Verrecchia Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, exerts neuroprotective effects in traumatic brain injury Neurosci Lett 388 2005 7 12
    • (2005) Neurosci Lett , vol.388 , pp. 7-12
    • Besson, V.C.1    Chen, X.R.2    Plotkine, M.3    Marchand-Verrecchia, C.4
  • 179
    • 34547118091 scopus 로고    scopus 로고
    • Neurological recovery-promoting, anti-inflammatory, and anti-oxidative effects afforded by fenofibrate, a PPAR alpha agonist, in traumatic brain injury
    • X.R. Chen, V.C. Besson, B. Palmier, Y. Garcia, M. Plotkine, and C. Marchand-Leroux Neurological recovery-promoting, anti-inflammatory, and anti-oxidative effects afforded by fenofibrate, a PPAR alpha agonist, in traumatic brain injury J Neurotrauma 24 2007 1119 1131
    • (2007) J Neurotrauma , vol.24 , pp. 1119-1131
    • Chen, X.R.1    Besson, V.C.2    Palmier, B.3    Garcia, Y.4    Plotkine, M.5    Marchand-Leroux, C.6
  • 180
    • 15544377692 scopus 로고    scopus 로고
    • Cloning and characterization of cyclooxygenase-1b (putative cyclooxygenase-3) in rat
    • J.A. Snipes, B. Kis, G.S. Shelness, J.A. Hewett, and D.W. Busija Cloning and characterization of cyclooxygenase-1b (putative cyclooxygenase-3) in rat J Pharmacol Exp Ther 313 2005 668 676
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 668-676
    • Snipes, J.A.1    Kis, B.2    Shelness, G.S.3    Hewett, J.A.4    Busija, D.W.5
  • 181
    • 0036669611 scopus 로고    scopus 로고
    • Cyclooxygenase isozymes and their gene structures and expression
    • T. Tanabe, and N. Tohnai Cyclooxygenase isozymes and their gene structures and expression Prostaglandins Other Lipid Mediat 6869 2002 95 114
    • (2002) Prostaglandins Other Lipid Mediat , vol.6869 , pp. 95-114
    • Tanabe, T.1    Tohnai, N.2
  • 182
    • 0029899186 scopus 로고    scopus 로고
    • A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors
    • J.K. Gierse, J.J. McDonald, S.D. Hauser, S.H. Rangwala, C.M. Koboldt, and K. Seibert A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors J Biol Chem 271 1996 15810 15814
    • (1996) J Biol Chem , vol.271 , pp. 15810-15814
    • Gierse, J.K.1    McDonald, J.J.2    Hauser, S.D.3    Rangwala, S.H.4    Koboldt, C.M.5    Seibert, K.6
  • 183
    • 0028902109 scopus 로고
    • Characterization of inducible cyclooxygenase in rat brain
    • C.D. Breder, D. Dewitt, and R.P. Kraig Characterization of inducible cyclooxygenase in rat brain J Comp Neurol 355 1995 296 315
    • (1995) J Comp Neurol , vol.355 , pp. 296-315
    • Breder, C.D.1    Dewitt, D.2    Kraig, R.P.3
  • 184
    • 0029995029 scopus 로고    scopus 로고
    • COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex
    • W.E. Kaufmann, P.F. Worley, J. Pegg, M. Bremer, and P. Isakson COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex Proc Natl Acad Sci USA 93 1996 2317 2321
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2317-2321
    • Kaufmann, W.E.1    Worley, P.F.2    Pegg, J.3    Bremer, M.4    Isakson, P.5
  • 185
    • 0027290813 scopus 로고
    • Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
    • K. Yamagata, K.I. Andreasson, W.E. Kaufmann, C.A. Barnes, and P.F. Worley Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids Neuron 11 1993 371 386
    • (1993) Neuron , vol.11 , pp. 371-386
    • Yamagata, K.1    Andreasson, K.I.2    Kaufmann, W.E.3    Barnes, C.A.4    Worley, P.F.5
  • 186
    • 0036082805 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity
    • C. Chen, J.C. Magee, and N.G. Bazan Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity J Neurophysiol 87 2002 2851 2857
    • (2002) J Neurophysiol , vol.87 , pp. 2851-2857
    • Chen, C.1    Magee, J.C.2    Bazan, N.G.3
  • 187
    • 12544250740 scopus 로고    scopus 로고
    • Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons
    • C. Chen, and N.G. Bazan Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons J Neurophysiol 93 2005 929 941
    • (2005) J Neurophysiol , vol.93 , pp. 929-941
    • Chen, C.1    Bazan, N.G.2
  • 188
    • 20744433041 scopus 로고    scopus 로고
    • Cyclo-oxygenase-1 and -2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N-methyl-D-aspartate receptors in rat hippocampus
    • O. Pepicelli, E. Fedele, M. Berardi, M. Raiteri, G. Levi, and A. Greco Cyclo-oxygenase-1 and -2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N-methyl-D-aspartate receptors in rat hippocampus J Neurochem 93 2005 1561 1567
    • (2005) J Neurochem , vol.93 , pp. 1561-1567
    • Pepicelli, O.1    Fedele, E.2    Berardi, M.3    Raiteri, M.4    Levi, G.5    Greco, A.6
  • 189
    • 33846845145 scopus 로고    scopus 로고
    • Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
    • E. Candelario-Jalil, A. Gonzalez-Falcon, M. Garcia-Cabrera, O.S. Leon, and B.L. Fiebich Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats J Neurochem 100 2007 1108 1120
    • (2007) J Neurochem , vol.100 , pp. 1108-1120
    • Candelario-Jalil, E.1    Gonzalez-Falcon, A.2    Garcia-Cabrera, M.3    Leon, O.S.4    Fiebich, B.L.5
  • 190
    • 35549002772 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-{alpha} in the rat
    • E. Candelario-Jalil, S. Taheri, Y. Yang, R. Sood, M. Grossetete, and E.Y. Estrada Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-{alpha} in the rat J Pharmacol Exp Ther 323 2007 488 498
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 488-498
    • Candelario-Jalil, E.1    Taheri, S.2    Yang, Y.3    Sood, R.4    Grossetete, M.5    Estrada, E.Y.6
  • 191
    • 0035205852 scopus 로고    scopus 로고
    • Increased susceptibility to ischemic brain injury in cyclooxygenase-1- deficient mice
    • C. Iadecola, K. Sugimoto, K. Niwa, K. Kazama, and M.E. Ross Increased susceptibility to ischemic brain injury in cyclooxygenase-1-deficient mice J Cereb Blood Flow Metab 21 2001 1436 1441
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1436-1441
    • Iadecola, C.1    Sugimoto, K.2    Niwa, K.3    Kazama, K.4    Ross, M.E.5
  • 192
    • 3843082003 scopus 로고    scopus 로고
    • Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death
    • K. Chu, S.W. Jeong, K.H. Jung, S.Y. Han, S.T. Lee, and M. Kim Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death J Cereb Blood Flow Metab 24 2004 926 933
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 926-933
    • Chu, K.1    Jeong, S.W.2    Jung, K.H.3    Han, S.Y.4    Lee, S.T.5    Kim, M.6
  • 193
    • 0033986676 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase 2 by nimesulide decreases prostaglandin E2 formation but does not alter brain edema or clinical recovery after closed head injury in rats
    • L. Koyfman, J. Kaplanski, A.A. Artru, D. Talmor, M. Rubin, and Y. Shapira Inhibition of cyclooxygenase 2 by nimesulide decreases prostaglandin E2 formation but does not alter brain edema or clinical recovery after closed head injury in rats J Neurosurg Anesthesiol 12 2000 44 50
    • (2000) J Neurosurg Anesthesiol , vol.12 , pp. 44-50
    • Koyfman, L.1    Kaplanski, J.2    Artru, A.A.3    Talmor, D.4    Rubin, M.5    Shapira, Y.6
  • 194
    • 0033852223 scopus 로고    scopus 로고
    • Prolonged cyclooxygenase-2 induction in neurons and glia following traumatic brain injury in the rat
    • K.I. Strauss, M.F. Barbe, R.M. Marshall, R. Raghupathi, S. Mehta, and R.K. Narayan Prolonged cyclooxygenase-2 induction in neurons and glia following traumatic brain injury in the rat J Neurotrauma 17 2000 695 711
    • (2000) J Neurotrauma , vol.17 , pp. 695-711
    • Strauss, K.I.1    Barbe, M.F.2    Marshall, R.M.3    Raghupathi, R.4    Mehta, S.5    Narayan, R.K.6
  • 195
    • 0036737399 scopus 로고    scopus 로고
    • Cyclooxygenase-2, prostaglandin synthases, and prostaglandin H2 metabolism in traumatic brain injury in the rat
    • T. Kunz, N. Marklund, L. Hillered, and E.H. Oliw Cyclooxygenase-2, prostaglandin synthases, and prostaglandin H2 metabolism in traumatic brain injury in the rat J Neurotrauma 19 2002 1051 1064
    • (2002) J Neurotrauma , vol.19 , pp. 1051-1064
    • Kunz, T.1    Marklund, N.2    Hillered, L.3    Oliw, E.H.4
  • 196
    • 0033984925 scopus 로고    scopus 로고
    • Regional expression and role of cyclooxygenase-2 following experimental traumatic brain injury
    • P.K. Dash, S.A. Mach, and A.N. Moore Regional expression and role of cyclooxygenase-2 following experimental traumatic brain injury J Neurotrauma 17 2000 69 81
    • (2000) J Neurotrauma , vol.17 , pp. 69-81
    • Dash, P.K.1    MacH, S.A.2    Moore, A.N.3
  • 197
    • 0036460393 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase 2 by nimesulide improves cognitive outcome more than motor outcome following diffuse traumatic brain injury in rats
    • I. Cernak, C. O'Connor, and R. Vink Inhibition of cyclooxygenase 2 by nimesulide improves cognitive outcome more than motor outcome following diffuse traumatic brain injury in rats Exp Brain Res 147 2002 193 199
    • (2002) Exp Brain Res , vol.147 , pp. 193-199
    • Cernak, I.1    O'Connor, C.2    Vink, R.3
  • 198
    • 0034856929 scopus 로고    scopus 로고
    • Traumatic brain injury induces prolonged accumulation of cyclooxygenase-1 expressing microglia/brain macrophages in rats
    • J.M. Schwab, K. Seid, and H.J. Schluesener Traumatic brain injury induces prolonged accumulation of cyclooxygenase-1 expressing microglia/brain macrophages in rats J Neurotrauma 18 2001 881 890
    • (2001) J Neurotrauma , vol.18 , pp. 881-890
    • Schwab, J.M.1    Seid, K.2    Schluesener, H.J.3
  • 199
    • 34548136578 scopus 로고    scopus 로고
    • Cyclooxygenase-2 activity following traumatic brain injury in the developing rat
    • R.W. Hickey, P.D. Adelson, M.J. Johnnides, D.S. Davis, Z. Yu, and M.E. Rose Cyclooxygenase-2 activity following traumatic brain injury in the developing rat Pediatr Res 62 2007 271 276
    • (2007) Pediatr Res , vol.62 , pp. 271-276
    • Hickey, R.W.1    Adelson, P.D.2    Johnnides, M.J.3    Davis, D.S.4    Yu, Z.5    Rose, M.E.6
  • 200
    • 20044362208 scopus 로고    scopus 로고
    • Cyclooxygenase-2-specific inhibitor improves functional outcomes, provides neuroprotection, and reduces inflammation in a rat model of traumatic brain injury
    • J.J. Gopez, H. Yue, R. Vasudevan, A.S. Malik, L.N. Fogelsanger, and S. Lewis Cyclooxygenase-2-specific inhibitor improves functional outcomes, provides neuroprotection, and reduces inflammation in a rat model of traumatic brain injury Neurosurgery 56 2005 590 604
    • (2005) Neurosurgery , vol.56 , pp. 590-604
    • Gopez, J.J.1    Yue, H.2    Vasudevan, R.3    Malik, A.S.4    Fogelsanger, L.N.5    Lewis, S.6
  • 201
    • 33644608758 scopus 로고    scopus 로고
    • Effects of the selective cyclooxygenase-2 inhibitor rofecoxib on cell death following traumatic brain injury in the rat
    • T. Kunz, N. Marklund, L. Hillered, and E.H. Oliw Effects of the selective cyclooxygenase-2 inhibitor rofecoxib on cell death following traumatic brain injury in the rat Restor Neurol Neurosci 24 2006 55 63
    • (2006) Restor Neurol Neurosci , vol.24 , pp. 55-63
    • Kunz, T.1    Marklund, N.2    Hillered, L.3    Oliw, E.H.4
  • 202
    • 70349757546 scopus 로고    scopus 로고
    • Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice
    • M.L. Kelso, S.W. Scheff, J.R. Pauly, and C.D. Loftin Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice BMC Neurosci 10 2009 108
    • (2009) BMC Neurosci , vol.10 , pp. 108
    • Kelso, M.L.1    Scheff, S.W.2    Pauly, J.R.3    Loftin, C.D.4
  • 203
    • 59349102320 scopus 로고    scopus 로고
    • Genetic disruption of cyclooxygenase-2 does not improve histological or behavioral outcome after traumatic brain injury in mice
    • M. Ahmad, M.E. Rose, V. Vagni, R.P. Griffith, C.E. Dixon, and P.M. Kochanek Genetic disruption of cyclooxygenase-2 does not improve histological or behavioral outcome after traumatic brain injury in mice J Neurosci Res 86 2008 3605 3612
    • (2008) J Neurosci Res , vol.86 , pp. 3605-3612
    • Ahmad, M.1    Rose, M.E.2    Vagni, V.3    Griffith, R.P.4    Dixon, C.E.5    Kochanek, P.M.6
  • 204
    • 19744380776 scopus 로고    scopus 로고
    • Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
    • R.S. Bresalier, R.S. Sandler, H. Quan, J.A. Bolognese, B. Oxenius, and K. Horgan Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial N Engl J Med 352 2005 1092 1102
    • (2005) N Engl J Med , vol.352 , pp. 1092-1102
    • Bresalier, R.S.1    Sandler, R.S.2    Quan, H.3    Bolognese, J.A.4    Oxenius, B.5    Horgan, K.6
  • 206
    • 33746629480 scopus 로고    scopus 로고
    • Phosphodiesterases in the CNS: Targets for drug development
    • F.S. Menniti, W.S. Faraci, and C.J. Schmidt Phosphodiesterases in the CNS: targets for drug development Nat Rev Drug Discov 5 2006 660 670
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 660-670
    • Menniti, F.S.1    Faraci, W.S.2    Schmidt, C.J.3
  • 208
    • 65849096324 scopus 로고    scopus 로고
    • Deficits in ERK and CREB activation in the hippocampus after traumatic brain injury
    • C.M. Atkins, M.C. Falo, O.F. Alonso, H.M. Bramlett, and W.D. Dietrich Deficits in ERK and CREB activation in the hippocampus after traumatic brain injury Neurosci Lett 459 2009 52 56
    • (2009) Neurosci Lett , vol.459 , pp. 52-56
    • Atkins, C.M.1    Falo, M.C.2    Alonso, O.F.3    Bramlett, H.M.4    Dietrich, W.D.5
  • 209
    • 34247366877 scopus 로고    scopus 로고
    • Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation
    • R.W. Chen, A.J. Williams, Z. Liao, C. Yao, F.C. Tortella, and J.R. Dave Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation Neurosci Lett 418 2007 165 169
    • (2007) Neurosci Lett , vol.418 , pp. 165-169
    • Chen, R.W.1    Williams, A.J.2    Liao, Z.3    Yao, C.4    Tortella, F.C.5    Dave, J.R.6
  • 210
    • 34748821818 scopus 로고    scopus 로고
    • Alterations of acetylcholinesterase activity after traumatic brain injury in rats
    • C.K. Donat, M.U. Schuhmann, C. Voigt, K. Nieber, R. Schliebs, and P. Brust Alterations of acetylcholinesterase activity after traumatic brain injury in rats Brain Inj 21 2007 1031 1037
    • (2007) Brain Inj , vol.21 , pp. 1031-1037
    • Donat, C.K.1    Schuhmann, M.U.2    Voigt, C.3    Nieber, K.4    Schliebs, R.5    Brust, P.6
  • 211
    • 85016855413 scopus 로고    scopus 로고
    • Rivastigmine, a brain-selective acetylcholinesterase inhibitor, ameliorates cognitive and motor deficits induced by closed-head injury in the mouse
    • Y. Chen, E. Shohami, S. Constantini, and M. Weinstock Rivastigmine, a brain-selective acetylcholinesterase inhibitor, ameliorates cognitive and motor deficits induced by closed-head injury in the mouse J Neurotrauma 15 1998 231 237
    • (1998) J Neurotrauma , vol.15 , pp. 231-237
    • Chen, Y.1    Shohami, E.2    Constantini, S.3    Weinstock, M.4
  • 212
    • 10944253680 scopus 로고    scopus 로고
    • Central acetylcholinesterase inhibitors in the treatment of chronic traumatic brain injury-clinical experience in 111 patients
    • O. Tenovuo Central acetylcholinesterase inhibitors in the treatment of chronic traumatic brain injury-clinical experience in 111 patients Prog Neuropsychopharmacol Biol Psychiatry 29 2005 61 67
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 61-67
    • Tenovuo, O.1
  • 213
    • 46649098179 scopus 로고    scopus 로고
    • Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury
    • M.A. Ansari, K.N. Roberts, and S.W. Scheff Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury Free Radic Biol Med 45 2008 443 452
    • (2008) Free Radic Biol Med , vol.45 , pp. 443-452
    • Ansari, M.A.1    Roberts, K.N.2    Scheff, S.W.3
  • 214
    • 43649103735 scopus 로고    scopus 로고
    • A time course of contusion-induced oxidative stress and synaptic proteins in cortex in a rat model of TBI
    • M.A. Ansari, K.N. Roberts, and S.W. Scheff A time course of contusion-induced oxidative stress and synaptic proteins in cortex in a rat model of TBI J Neurotrauma 25 2008 513 526
    • (2008) J Neurotrauma , vol.25 , pp. 513-526
    • Ansari, M.A.1    Roberts, K.N.2    Scheff, S.W.3
  • 215
    • 0033789565 scopus 로고    scopus 로고
    • Free radical pathways in CNS injury
    • A. Lewen, P. Matz, and P.H. Chan Free radical pathways in CNS injury J Neurotrauma 17 2000 871 890
    • (2000) J Neurotrauma , vol.17 , pp. 871-890
    • Lewen, A.1    Matz, P.2    Chan, P.H.3
  • 216
    • 0022628380 scopus 로고
    • Superoxide production in experimental brain injury
    • H.A. Kontos, and E.P. Wei Superoxide production in experimental brain injury J Neurosurg 64 1986 803 807
    • (1986) J Neurosurg , vol.64 , pp. 803-807
    • Kontos, H.A.1    Wei, E.P.2
  • 217
    • 0027400110 scopus 로고
    • Brain hydroxyl radical generation in acute experimental head injury
    • E.D. Hall, P.K. Andrus, and P.A. Yonkers Brain hydroxyl radical generation in acute experimental head injury J Neurochem 60 1993 588 594
    • (1993) J Neurochem , vol.60 , pp. 588-594
    • Hall, E.D.1    Andrus, P.K.2    Yonkers, P.A.3
  • 218
    • 34249096439 scopus 로고    scopus 로고
    • Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury
    • W.O. Opii, V.N. Nukala, R. Sultana, J.D. Pandya, K.M. Day, and M.L. Merchant Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury J Neurotrauma 24 2007 772 789
    • (2007) J Neurotrauma , vol.24 , pp. 772-789
    • Opii, W.O.1    Nukala, V.N.2    Sultana, R.3    Pandya, J.D.4    Day, K.M.5    Merchant, M.L.6
  • 219
    • 34247203094 scopus 로고    scopus 로고
    • Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury
    • Y. Deng, B.M. Thompson, X. Gao, and E.D. Hall Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury Exp Neurol 205 2007 154 165
    • (2007) Exp Neurol , vol.205 , pp. 154-165
    • Deng, Y.1    Thompson, B.M.2    Gao, X.3    Hall, E.D.4
  • 221
    • 0029761661 scopus 로고    scopus 로고
    • Effects of pegorgotein on neurologic outcome of patients with severe head injury. A multicenter, randomized controlled trial
    • B. Young, J.W. Runge, K.S. Waxman, T. Harrington, J. Wilberger, and J.P. Muizelaar Effects of pegorgotein on neurologic outcome of patients with severe head injury. A multicenter, randomized controlled trial Jama 276 1996 538 543
    • (1996) Jama , vol.276 , pp. 538-543
    • Young, B.1    Runge, J.W.2    Waxman, K.S.3    Harrington, T.4    Wilberger, J.5    Muizelaar, J.P.6
  • 222
    • 77953304579 scopus 로고    scopus 로고
    • Mitochondrial protection after traumatic brain injury by scavenging lipid peroxyl radicals
    • A.G. Mustafa, I.N. Singh, J. Wang, K.M. Carrico, and E.D. Hall Mitochondrial protection after traumatic brain injury by scavenging lipid peroxyl radicals J Neurochem 114 2010 271 280
    • (2010) J Neurochem , vol.114 , pp. 271-280
    • Mustafa, A.G.1    Singh, I.N.2    Wang, J.3    Carrico, K.M.4    Hall, E.D.5
  • 225
  • 226
    • 19744380563 scopus 로고    scopus 로고
    • Neuroscience: Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • DOI 10.1126/science.1110647
    • A. Nimmerjahn, F. Kirchhoff, and F. Helmchen Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo Science 308 2005 1314 1318 (Pubitemid 40746128)
    • (2005) Science , vol.308 , Issue.5726 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 227
    • 15244350494 scopus 로고    scopus 로고
    • Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand
    • D.L. Taylor, F. Jones, E.S. Kubota, and J.M. Pocock Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand J Neurosci 25 2005 2952 2964
    • (2005) J Neurosci , vol.25 , pp. 2952-2964
    • Taylor, D.L.1    Jones, F.2    Kubota, E.S.3    Pocock, J.M.4
  • 228
    • 11144355227 scopus 로고    scopus 로고
    • Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors
    • R.D. Shytle, T. Mori, K. Townsend, M. Vendrame, N. Sun, and J. Zeng Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors J Neurochem 89 2004 337 343
    • (2004) J Neurochem , vol.89 , pp. 337-343
    • Shytle, R.D.1    Mori, T.2    Townsend, K.3    Vendrame, M.4    Sun, N.5    Zeng, J.6
  • 229
    • 33746035655 scopus 로고    scopus 로고
    • Translocator protein (18kDa): New nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
    • V. Papadopoulos, M. Baraldi, T.R. Guilarte, T.B. Knudsen, J.J. Lacapere, and P. Lindemann Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function Trends Pharmacol Sci 27 2006 402 409
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 402-409
    • Papadopoulos, V.1    Baraldi, M.2    Guilarte, T.R.3    Knudsen, T.B.4    Lacapere, J.J.5    Lindemann, P.6
  • 230
    • 0038374983 scopus 로고    scopus 로고
    • Time course of cellular pathology after controlled cortical impact injury
    • S. Chen, J.D. Pickard, and N.G. Harris Time course of cellular pathology after controlled cortical impact injury Exp Neurol 182 2003 87 102
    • (2003) Exp Neurol , vol.182 , pp. 87-102
    • Chen, S.1    Pickard, J.D.2    Harris, N.G.3
  • 231
    • 0042213235 scopus 로고    scopus 로고
    • Traumatic brain injury leads to increased expression of peripheral-type benzodiazepine receptors, neuronal death, and activation of astrocytes and microglia in rat thalamus
    • V.L. Raghavendra Rao, A. Dogan, K.K. Bowen, and R.J. Dempsey Traumatic brain injury leads to increased expression of peripheral-type benzodiazepine receptors, neuronal death, and activation of astrocytes and microglia in rat thalamus Exp Neurol 161 2000 102 114
    • (2000) Exp Neurol , vol.161 , pp. 102-114
    • Raghavendra Rao, V.L.1    Dogan, A.2    Bowen, K.K.3    Dempsey, R.J.4
  • 232
    • 0346995476 scopus 로고    scopus 로고
    • Increase in peripheral benzodiazepine receptors and loss of glutamate NMDA receptors in a mouse model of closed head injury: A quantitative autoradiographic study
    • R. Grossman, E. Shohami, A. Alexandrovich, I. Yatsiv, Y. Kloog, and A. Biegon Increase in peripheral benzodiazepine receptors and loss of glutamate NMDA receptors in a mouse model of closed head injury: a quantitative autoradiographic study Neuroimage 20 2003 1971 1981
    • (2003) Neuroimage , vol.20 , pp. 1971-1981
    • Grossman, R.1    Shohami, E.2    Alexandrovich, A.3    Yatsiv, I.4    Kloog, Y.5    Biegon, A.6
  • 233
    • 0011970183 scopus 로고    scopus 로고
    • Antimicrobial agents (continued): Protein synthesis inhibitors and miscellaneous antibacterial agents
    • H.F. Chambers Antimicrobial agents (continued): protein synthesis inhibitors and miscellaneous antibacterial agents J.G. Hardman, L.E. Limbird, A.G. Gilman, Goodman and Gilman's the pharmacological basis of therapeutics 10th ed. 2001 McGraw-Hill New York 1239 1271
    • (2001) Goodman and Gilman's the Pharmacological Basis of Therapeutics , pp. 1239-1271
    • Chambers, H.F.1
  • 234
    • 0032442475 scopus 로고    scopus 로고
    • Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
    • J. Yrjanheikki, R. Keinanen, M. Pellikka, T. Hokfelt, and J. Koistinaho Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia Proc Natl Acad Sci USA 95 1998 15769 15774
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15769-15774
    • Yrjanheikki, J.1    Keinanen, R.2    Pellikka, M.3    Hokfelt, T.4    Koistinaho, J.5
  • 235
    • 0033539522 scopus 로고    scopus 로고
    • A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
    • J. Yrjanheikki, T. Tikka, R. Keinanen, G. Goldsteins, P.H. Chan, and J. Koistinaho A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window Proc Natl Acad Sci USA 96 1999 13496 13500
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13496-13500
    • Yrjanheikki, J.1    Tikka, T.2    Keinanen, R.3    Goldsteins, G.4    Chan, P.H.5    Koistinaho, J.6
  • 236
    • 34848857092 scopus 로고    scopus 로고
    • Minocycline treatment in acute stroke: An open-label, evaluator-blinded study
    • Y. Lampl, M. Boaz, R. Gilad, M. Lorberboym, R. Dabby, and A. Rapoport Minocycline treatment in acute stroke: an open-label, evaluator-blinded study Neurology 69 2007 1404 1410
    • (2007) Neurology , vol.69 , pp. 1404-1410
    • Lampl, Y.1    Boaz, M.2    Gilad, R.3    Lorberboym, M.4    Dabby, R.5    Rapoport, A.6
  • 237
    • 33847326193 scopus 로고    scopus 로고
    • Differential neuroprotective effects of a minocycline-based drug cocktail in transient and permanent focal cerebral ischemia
    • Y.C. Weng, and J. Kriz Differential neuroprotective effects of a minocycline-based drug cocktail in transient and permanent focal cerebral ischemia Exp Neurol 204 2007 433 442
    • (2007) Exp Neurol , vol.204 , pp. 433-442
    • Weng, Y.C.1    Kriz, J.2
  • 238
    • 41249088005 scopus 로고    scopus 로고
    • Delayed treatment with minocycline ameliorates neurologic impairment through activated microglia expressing a high-mobility group box1-inhibiting mechanism
    • K. Hayakawa, K. Mishima, M. Nozako, M. Hazekawa, S. Mishima, and M. Fujioka Delayed treatment with minocycline ameliorates neurologic impairment through activated microglia expressing a high-mobility group box1-inhibiting mechanism Stroke 39 2008 951 958
    • (2008) Stroke , vol.39 , pp. 951-958
    • Hayakawa, K.1    Mishima, K.2    Nozako, M.3    Hazekawa, M.4    Mishima, S.5    Fujioka, M.6
  • 239
    • 33845938979 scopus 로고    scopus 로고
    • Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia
    • Z. Liu, Y. Fan, S.J. Won, M. Neumann, D. Hu, and L. Zhou Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia Stroke 38 2007 146 152
    • (2007) Stroke , vol.38 , pp. 146-152
    • Liu, Z.1    Fan, Y.2    Won, S.J.3    Neumann, M.4    Hu, D.5    Zhou, L.6
  • 240
    • 33847261481 scopus 로고    scopus 로고
    • Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration
    • N. Bye, M.D. Habgood, J.K. Callaway, N. Malakooti, A. Potter, and T. Kossmann Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration Exp Neurol 204 2007 220 233
    • (2007) Exp Neurol , vol.204 , pp. 220-233
    • Bye, N.1    Habgood, M.D.2    Callaway, J.K.3    Malakooti, N.4    Potter, A.5    Kossmann, T.6
  • 241
    • 0035876916 scopus 로고    scopus 로고
    • Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia
    • T.M. Tikka, and J.E. Koistinaho Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia J Immunol 166 2001 7527 7533
    • (2001) J Immunol , vol.166 , pp. 7527-7533
    • Tikka, T.M.1    Koistinaho, J.E.2
  • 242
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • T. Tikka, B.L. Fiebich, G. Goldsteins, R. Keinanen, and J. Koistinaho Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia J Neurosci 21 2001 2580 2588
    • (2001) J Neurosci , vol.21 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 243
    • 0034998271 scopus 로고    scopus 로고
    • Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction
    • R.O. Sanchez Mejia, V.O. Ona, M. Li, and R.M. Friedlander Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction Neurosurgery 48 2001 1393 1399 discussion 1399401
    • (2001) Neurosurgery , vol.48 , pp. 1393-1399
    • Sanchez Mejia, R.O.1    Ona, V.O.2    Li, M.3    Friedlander, R.M.4
  • 244
    • 77952972556 scopus 로고    scopus 로고
    • Blockade of acute microglial activation by minocycline promotes neuroprotection and reduces locomotor hyperactivity after closed head injury in mice: A twelve-week follow-up study
    • S. Homsi, T. Piaggio, N. Croci, F. Noble, M. Plotkine, and C. Marchand-Leroux Blockade of acute microglial activation by minocycline promotes neuroprotection and reduces locomotor hyperactivity after closed head injury in mice: a twelve-week follow-up study J Neurotrauma 27 2010 911 921
    • (2010) J Neurotrauma , vol.27 , pp. 911-921
    • Homsi, S.1    Piaggio, T.2    Croci, N.3    Noble, F.4    Plotkine, M.5    Marchand-Leroux, C.6
  • 245
    • 64149122741 scopus 로고    scopus 로고
    • Synapse loss regulated by matrix metalloproteinases in traumatic brain injury is associated with hypoxia inducible factor-1alpha expression
    • J.Y. Ding, C.W. Kreipke, P. Schafer, S. Schafer, S.L. Speirs, and J.A. Rafols Synapse loss regulated by matrix metalloproteinases in traumatic brain injury is associated with hypoxia inducible factor-1alpha expression Brain Res 1268 2009 125 134
    • (2009) Brain Res , vol.1268 , pp. 125-134
    • Ding, J.Y.1    Kreipke, C.W.2    Schafer, P.3    Schafer, S.4    Speirs, S.L.5    Rafols, J.A.6
  • 246
    • 0032878575 scopus 로고    scopus 로고
    • Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents
    • S.W. Scheff, and P.G. Sullivan Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents J Neurotrauma 16 1999 783 792
    • (1999) J Neurotrauma , vol.16 , pp. 783-792
    • Scheff, S.W.1    Sullivan, P.G.2
  • 247
    • 67649772111 scopus 로고    scopus 로고
    • The role of mitochondrial transition pore, and its modulation, in traumatic brain injury and delayed neurodegeneration after TBI
    • A.T. Mazzeo, A. Beat, A. Singh, and M.R. Bullock The role of mitochondrial transition pore, and its modulation, in traumatic brain injury and delayed neurodegeneration after TBI Exp Neurol 218 2009 363 370
    • (2009) Exp Neurol , vol.218 , pp. 363-370
    • Mazzeo, A.T.1    Beat, A.2    Singh, A.3    Bullock, M.R.4
  • 248
    • 55949111684 scopus 로고    scopus 로고
    • Dosing and safety of cyclosporine in patients with severe brain injury
    • J. Hatton, B. Rosbolt, P. Empey, R. Kryscio, and B. Young Dosing and safety of cyclosporine in patients with severe brain injury J Neurosurg 109 2008 699 707
    • (2008) J Neurosurg , vol.109 , pp. 699-707
    • Hatton, J.1    Rosbolt, B.2    Empey, P.3    Kryscio, R.4    Young, B.5
  • 249
    • 0032736595 scopus 로고    scopus 로고
    • Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury
    • P.G. Sullivan, M.B. Thompson, and S.W. Scheff Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury Exp Neurol 160 1999 226 234
    • (1999) Exp Neurol , vol.160 , pp. 226-234
    • Sullivan, P.G.1    Thompson, M.B.2    Scheff, S.W.3
  • 250
    • 0034057187 scopus 로고    scopus 로고
    • Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury
    • P.G. Sullivan, M. Thompson, and S.W. Scheff Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury Exp Neurol 161 2000 631 637
    • (2000) Exp Neurol , vol.161 , pp. 631-637
    • Sullivan, P.G.1    Thompson, M.2    Scheff, S.W.3
  • 251
    • 0034005586 scopus 로고    scopus 로고
    • Cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity
    • B.C. Albensi, P.G. Sullivan, M.B. Thompson, S.W. Scheff, and M.P. Mattson Cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity Exp Neurol 162 2000 385 389
    • (2000) Exp Neurol , vol.162 , pp. 385-389
    • Albensi, B.C.1    Sullivan, P.G.2    Thompson, M.B.3    Scheff, S.W.4    Mattson, M.P.5
  • 252
    • 0036329446 scopus 로고    scopus 로고
    • Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats
    • B. Alessandri, A.C. Rice, J. Levasseur, M. DeFord, R.J. Hamm, and M.R. Bullock Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats J Neurotrauma 19 2002 829 841
    • (2002) J Neurotrauma , vol.19 , pp. 829-841
    • Alessandri, B.1    Rice, A.C.2    Levasseur, J.3    Deford, M.4    Hamm, R.J.5    Bullock, M.R.6
  • 253
    • 0034836502 scopus 로고    scopus 로고
    • Effects of chronic, post-injury Cyclosporin A administration on motor and sensorimotor function following severe, experimental traumatic brain injury
    • P. Riess, F.M. Bareyre, K.E. Saatman, J.A. Cheney, J. Lifshitz, and R. Raghupathi Effects of chronic, post-injury Cyclosporin A administration on motor and sensorimotor function following severe, experimental traumatic brain injury Restor Neurol Neurosci 18 2001 1 8
    • (2001) Restor Neurol Neurosci , vol.18 , pp. 1-8
    • Riess, P.1    Bareyre, F.M.2    Saatman, K.E.3    Cheney, J.A.4    Lifshitz, J.5    Raghupathi, R.6
  • 254
    • 72949118213 scopus 로고    scopus 로고
    • Safety and tolerability of cyclosporin a in severe traumatic brain injury patients: Results from a prospective randomized trial
    • A.T. Mazzeo, G.M. Brophy, C.B. Gilman, O.L. Alves, J.R. Robles, and R.L. Hayes Safety and tolerability of cyclosporin a in severe traumatic brain injury patients: results from a prospective randomized trial J Neurotrauma 26 2009 2195 2206
    • (2009) J Neurotrauma , vol.26 , pp. 2195-2206
    • Mazzeo, A.T.1    Brophy, G.M.2    Gilman, C.B.3    Alves, O.L.4    Robles, J.R.5    Hayes, R.L.6
  • 255
    • 58149161871 scopus 로고    scopus 로고
    • Comparative neuroprotective effects of cyclosporin A and NIM811, a nonimmunosuppressive cyclosporin A analog, following traumatic brain injury
    • L.H. Mbye, I.N. Singh, K.M. Carrico, K.E. Saatman, and E.D. Hall Comparative neuroprotective effects of cyclosporin A and NIM811, a nonimmunosuppressive cyclosporin A analog, following traumatic brain injury J Cereb Blood Flow Metab 29 2009 87 97
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 87-97
    • Mbye, L.H.1    Singh, I.N.2    Carrico, K.M.3    Saatman, K.E.4    Hall, E.D.5
  • 256
    • 3042591642 scopus 로고    scopus 로고
    • Endothelins and the role of endothelin antagonists in the management of posttraumatic vasospasm
    • W.M. Armstead Endothelins and the role of endothelin antagonists in the management of posttraumatic vasospasm Curr Pharm Des 10 2004 2185 2192
    • (2004) Curr Pharm des , vol.10 , pp. 2185-2192
    • Armstead, W.M.1
  • 257
    • 34249105589 scopus 로고    scopus 로고
    • Biphasic elevation in cerebrospinal fluid and plasma concentrations of endothelin 1 after traumatic brain injury in human patients
    • B. Maier, M. Lehnert, H.L. Laurer, and I. Marzi Biphasic elevation in cerebrospinal fluid and plasma concentrations of endothelin 1 after traumatic brain injury in human patients Shock 27 2007 610 614
    • (2007) Shock , vol.27 , pp. 610-614
    • Maier, B.1    Lehnert, M.2    Laurer, H.L.3    Marzi, I.4
  • 259
    • 77958187588 scopus 로고    scopus 로고
    • Endothelin-1 is increased in cerebrospinal fluid and associated with unfavorable outcomes in children after severe traumatic brain injury
    • R. Salonia, P. Empey, S.M. Poloyac, S.R. Wisniewski, M. Klamerus, and H. Ozawa Endothelin-1 is increased in cerebrospinal fluid and associated with unfavorable outcomes in children after severe traumatic brain injury J Neurotrauma 27 2010 1819 1825
    • (2010) J Neurotrauma , vol.27 , pp. 1819-1825
    • Salonia, R.1    Empey, P.2    Poloyac, S.M.3    Wisniewski, S.R.4    Klamerus, M.5    Ozawa, H.6
  • 260
    • 77953119519 scopus 로고    scopus 로고
    • Brain cellular localization of endothelin receptors A and B in a rodent model of diffuse traumatic brain injury
    • S. Kallakuri, C.W. Kreipke, P.C. Schafer, S.M. Schafer, and J.A. Rafols Brain cellular localization of endothelin receptors A and B in a rodent model of diffuse traumatic brain injury Neuroscience 168 2010 820 830
    • (2010) Neuroscience , vol.168 , pp. 820-830
    • Kallakuri, S.1    Kreipke, C.W.2    Schafer, P.C.3    Schafer, S.M.4    Rafols, J.A.5
  • 261
    • 77949453819 scopus 로고    scopus 로고
    • Differential effects of endothelin receptor A and B antagonism on cerebral hypoperfusion following traumatic brain injury
    • C.W. Kreipke, P.C. Schafer, N.F. Rossi, and J.A. Rafols Differential effects of endothelin receptor A and B antagonism on cerebral hypoperfusion following traumatic brain injury Neurol Res 32 2010 209 214
    • (2010) Neurol Res , vol.32 , pp. 209-214
    • Kreipke, C.W.1    Schafer, P.C.2    Rossi, N.F.3    Rafols, J.A.4
  • 262
    • 0032569679 scopus 로고    scopus 로고
    • Involvement of the endothelin receptor subtype A in neuronal pathogenesis after traumatic brain injury
    • M. Sato, and L.J. Noble Involvement of the endothelin receptor subtype A in neuronal pathogenesis after traumatic brain injury Brain Res 809 1998 39 49
    • (1998) Brain Res , vol.809 , pp. 39-49
    • Sato, M.1    Noble, L.J.2
  • 264
    • 0031410384 scopus 로고    scopus 로고
    • Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons
    • M. Alkondon, E.F. Pereira, W.S. Cortes, A. Maelicke, and E.X. Albuquerque Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons Eur J Neurosci 9 1997 2734 2742
    • (1997) Eur J Neurosci , vol.9 , pp. 2734-2742
    • Alkondon, M.1    Pereira, E.F.2    Cortes, W.S.3    Maelicke, A.4    Albuquerque, E.X.5
  • 265
    • 0032105398 scopus 로고    scopus 로고
    • Contribution of nicotinic receptors to the function of synapses in the central nervous system: The action of choline as a selective agonist of alpha 7 receptors
    • E.X. Albuquerque, E.F. Pereira, M.F. Braga, and M. Alkondon Contribution of nicotinic receptors to the function of synapses in the central nervous system: the action of choline as a selective agonist of alpha 7 receptors J Physiol Paris 92 1998 309 316
    • (1998) J Physiol Paris , vol.92 , pp. 309-316
    • Albuquerque, E.X.1    Pereira, E.F.2    Braga, M.F.3    Alkondon, M.4
  • 266
    • 50149114171 scopus 로고    scopus 로고
    • Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury
    • M.V. Guseva, D.M. Hopkins, S.W. Scheff, and J.R. Pauly Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury J Neurotrauma 25 2008 975 983
    • (2008) J Neurotrauma , vol.25 , pp. 975-983
    • Guseva, M.V.1    Hopkins, D.M.2    Scheff, S.W.3    Pauly, J.R.4
  • 267
    • 0033767740 scopus 로고    scopus 로고
    • Dietary supplement creatine protects against traumatic brain injury
    • P.G. Sullivan, J.D. Geiger, M.P. Mattson, and S.W. Scheff Dietary supplement creatine protects against traumatic brain injury Ann Neurol 48 2000 723 729
    • (2000) Ann Neurol , vol.48 , pp. 723-729
    • Sullivan, P.G.1    Geiger, J.D.2    Mattson, M.P.3    Scheff, S.W.4
  • 268
    • 33747585833 scopus 로고    scopus 로고
    • Prevention of complications related to traumatic brain injury in children and adolescents with creatine administration: An open label randomized pilot study
    • G. Sakellaris, M. Kotsiou, M. Tamiolaki, G. Kalostos, E. Tsapaki, and M. Spanaki Prevention of complications related to traumatic brain injury in children and adolescents with creatine administration: an open label randomized pilot study J Trauma 61 2006 322 329
    • (2006) J Trauma , vol.61 , pp. 322-329
    • Sakellaris, G.1    Kotsiou, M.2    Tamiolaki, M.3    Kalostos, G.4    Tsapaki, E.5    Spanaki, M.6
  • 269
    • 33645402334 scopus 로고    scopus 로고
    • Melatonin receptors in humans: Biological role and clinical relevance
    • C. Ekmekcioglu Melatonin receptors in humans: biological role and clinical relevance Biomed Pharmacother 60 2006 97 108
    • (2006) Biomed Pharmacother , vol.60 , pp. 97-108
    • Ekmekcioglu, C.1
  • 270
    • 0033768749 scopus 로고    scopus 로고
    • Actions of melatonin in the reduction of oxidative stress. A review
    • R.J. Reiter, D.X. Tan, C. Osuna, and E. Gitto Actions of melatonin in the reduction of oxidative stress. A review J Biomed Sci 7 2000 444 458
    • (2000) J Biomed Sci , vol.7 , pp. 444-458
    • Reiter, R.J.1    Tan, D.X.2    Osuna, C.3    Gitto, E.4
  • 271
    • 0030752296 scopus 로고    scopus 로고
    • Melatonin in relation to cellular antioxidative defense mechanisms
    • R.J. Reiter, R.C. Carneiro, and C.S. Oh Melatonin in relation to cellular antioxidative defense mechanisms Horm Metab Res 29 1997 363 372
    • (1997) Horm Metab Res , vol.29 , pp. 363-372
    • Reiter, R.J.1    Carneiro, R.C.2    Oh, C.S.3
  • 272
    • 1342268351 scopus 로고    scopus 로고
    • Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1
    • S.M. Beni, R. Kohen, R.J. Reiter, D.X. Tan, and E. Shohami Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1 FASEB J 18 2004 149 151
    • (2004) FASEB J , vol.18 , pp. 149-151
    • Beni, S.M.1    Kohen, R.2    Reiter, R.J.3    Tan, D.X.4    Shohami, E.5
  • 274
    • 33748310905 scopus 로고    scopus 로고
    • Effect of pinealectomy and melatonin replacement on morphological and biochemical recovery after traumatic brain injury
    • O. Ates, S. Cayli, I. Gurses, N. Yucel, M. Iraz, and E. Altinoz Effect of pinealectomy and melatonin replacement on morphological and biochemical recovery after traumatic brain injury Int J Dev Neurosci 24 2006 357 363
    • (2006) Int J Dev Neurosci , vol.24 , pp. 357-363
    • Ates, O.1    Cayli, S.2    Gurses, I.3    Yucel, N.4    Iraz, M.5    Altinoz, E.6
  • 275
    • 0025719095 scopus 로고
    • Diffuse prolonged depression of cerebral oxidative metabolism following concussive brain injury in the rat: A cytochrome oxidase histochemistry study
    • D.A. Hovda, A. Yoshino, T. Kawamata, Y. Katayama, and D.P. Becker Diffuse prolonged depression of cerebral oxidative metabolism following concussive brain injury in the rat: a cytochrome oxidase histochemistry study Brain Res 567 1991 1 10
    • (1991) Brain Res , vol.567 , pp. 1-10
    • Hovda, D.A.1    Yoshino, A.2    Kawamata, T.3    Katayama, Y.4    Becker, D.P.5
  • 276
    • 0026048155 scopus 로고
    • Dynamic changes in local cerebral glucose utilization following cerebral conclusion in rats: Evidence of a hyper- and subsequent hypometabolic state
    • A. Yoshino, D.A. Hovda, T. Kawamata, Y. Katayama, and D.P. Becker Dynamic changes in local cerebral glucose utilization following cerebral conclusion in rats: evidence of a hyper- and subsequent hypometabolic state Brain Res 561 1991 106 119
    • (1991) Brain Res , vol.561 , pp. 106-119
    • Yoshino, A.1    Hovda, D.A.2    Kawamata, T.3    Katayama, Y.4    Becker, D.P.5
  • 277
    • 3343008579 scopus 로고    scopus 로고
    • Increased cerebral uptake and oxidation of exogenous betaHB improves ATP following traumatic brain injury in adult rats
    • M.L. Prins, S.M. Lee, L.S. Fujima, and D.A. Hovda Increased cerebral uptake and oxidation of exogenous betaHB improves ATP following traumatic brain injury in adult rats J Neurochem 90 2004 666 672
    • (2004) J Neurochem , vol.90 , pp. 666-672
    • Prins, M.L.1    Lee, S.M.2    Fujima, L.S.3    Hovda, D.A.4
  • 279
    • 64849096855 scopus 로고    scopus 로고
    • The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat
    • K.S. Appelberg, D.A. Hovda, and M.L. Prins The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat J Neurotrauma 26 2009 497 506
    • (2009) J Neurotrauma , vol.26 , pp. 497-506
    • Appelberg, K.S.1    Hovda, D.A.2    Prins, M.L.3
  • 280
    • 27644461807 scopus 로고    scopus 로고
    • Age-dependent reduction of cortical contusion volume by ketones after traumatic brain injury
    • M.L. Prins, L.S. Fujima, and D.A. Hovda Age-dependent reduction of cortical contusion volume by ketones after traumatic brain injury J Neurosci Res 82 2005 413 420
    • (2005) J Neurosci Res , vol.82 , pp. 413-420
    • Prins, M.L.1    Fujima, L.S.2    Hovda, D.A.3
  • 281
    • 72949118683 scopus 로고    scopus 로고
    • Traumatic brain injury: Therapeutic challenges and new directions
    • R. Vink, and M.R. Bullock Traumatic brain injury: therapeutic challenges and new directions Neurotherapeutics 7 2010 1 2
    • (2010) Neurotherapeutics , vol.7 , pp. 1-2
    • Vink, R.1    Bullock, M.R.2
  • 282
    • 0006759303 scopus 로고    scopus 로고
    • [Internet]. Rockville, MD: U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Surveillance and Epidemiology; [updated 06/23/2010; cited 06/28/2010]
    • MedWatch: The FDA Safety Information and Adverse Event Reporting Program [Internet]. Rockville, MD: U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Surveillance and Epidemiology; [updated 06/23/2010; cited 06/28/2010]. http://www.fda.gov/Safety/MedWatch/default.htm
    • MedWatch: The FDA Safety Information and Adverse Event Reporting Program
  • 283
    • 0344065373 scopus 로고    scopus 로고
    • Recommendations for standards regarding preclinical neuroprotective and restorative drug development
    • M. Fisher Recommendations for standards regarding preclinical neuroprotective and restorative drug development Stroke 30 1999 2752 2758
    • (1999) Stroke , vol.30 , pp. 2752-2758
    • Fisher, M.1
  • 284
    • 0036913056 scopus 로고    scopus 로고
    • Neuroprotection and traumatic brain injury: Theoretical option or realistic proposition
    • A.I. Faden Neuroprotection and traumatic brain injury: theoretical option or realistic proposition Curr Opin Neurol 15 2002 707 712
    • (2002) Curr Opin Neurol , vol.15 , pp. 707-712
    • Faden, A.I.1
  • 285
    • 0034787937 scopus 로고    scopus 로고
    • Neuroprotection and traumatic brain injury: The search continues
    • A.I. Faden Neuroprotection and traumatic brain injury: the search continues Arch Neurol 58 2001 1553 1555
    • (2001) Arch Neurol , vol.58 , pp. 1553-1555
    • Faden, A.I.1
  • 286
    • 37549068172 scopus 로고    scopus 로고
    • Missing steps in the STAIR case: A Translational Medicine perspective on the development of NXY-059 for treatment of acute ischemic stroke
    • G.Z. Feuerstein, M.M. Zaleska, M. Krams, X. Wang, M. Day, and J.L. Rutkowski Missing steps in the STAIR case: a Translational Medicine perspective on the development of NXY-059 for treatment of acute ischemic stroke J Cereb Blood Flow Metab 28 2008 217 219
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 217-219
    • Feuerstein, G.Z.1    Zaleska, M.M.2    Krams, M.3    Wang, X.4    Day, M.5    Rutkowski, J.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.