Prostanoid EP1 receptor antagonist reduces blood-brain barrier leakage after cerebral ischemia

European Journal of Pharmacology

Volumn 640, Issue 1-3, 2010, Pages 82-86

  Fukumoto, Ken Ichi ^a   Takagi, Norio ^a   Yamamoto, Ritsuko ^a   Moriyama, Yoshiyuki ^a   Takeo, Satoshi ^a   Tanonaka, Kouichi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Blood brain barrier; Brain capillaries; Cerebral ischemia; Occludin; Prostanoid EP1 receptor; Tyrosine phosphorylation

Indexed keywords

HYDRAZIDE DERIVATIVE; OCCLUDIN; PROSTANOID EP 1 RECEPTOR; PROSTANOID RECEPTOR; RECEPTOR BLOCKING AGENT; TYROSINE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; FITC ALBUMIN; FITC-ALBUMIN; FLUORESCEIN ISOTHIOCYANATE; HYDRAZINE DERIVATIVE; MEMBRANE PROTEIN; OXAZEPINE DERIVATIVE; PROSTAGLANDIN E RECEPTOR; PROSTANOID RECEPTOR EP1; PROTEIN KINASE P60; SC 51089; SERUM ALBUMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; BRAIN CAPILLARY; BRAIN ISCHEMIA; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TIGHT JUNCTION; ANIMAL; CAPILLARY; CAPILLARY PERMEABILITY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; WISTAR RAT;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; CAPILLARIES; CAPILLARY PERMEABILITY; FLUORESCEIN-5-ISOTHIOCYANATE; HYDRAZINES; MALE; MEMBRANE PROTEINS; OXAZEPINES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RATS; RATS, WISTAR; RECEPTORS, PROSTAGLANDIN E; SERUM ALBUMIN; TYROSINE;

EID: 77953807028     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.05.001     Document Type: Article

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