메뉴 건너뛰기




Volumn 53, Issue 4, 2002, Pages 457-478

Desensitization of neuronal nicotinic receptors

Author keywords

Addiction; Allosteric; Inactivation; Phosphorylation; Synaptic plasticity

Indexed keywords

CHOLINESTERASE INHIBITOR; ION CHANNEL; NICOTINIC RECEPTOR;

EID: 0036891571     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10109     Document Type: Article
Times cited : (404)

References (155)
  • 1
    • 0025719239 scopus 로고
    • Initial characterization of the nicotinic acetylcholine receptors in rat hippocampal neurons
    • Alkondon M, Albuquerque EX. 1991. Initial characterization of the nicotinic acetylcholine receptors in rat hippocampal neurons. J Recept Res 11:1001-1021.
    • (1991) J Recept Res , vol.11 , pp. 1001-1021
    • Alkondon, M.1    Albuquerque, E.X.2
  • 2
    • 0033815626 scopus 로고    scopus 로고
    • Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus
    • Alkondon M, Pereira EFR, Almeida LEF, Randall WR, Albuquerque EX. 2000. Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus. Neuropharmacology 39:2726-2739.
    • (2000) Neuropharmacology , vol.39 , pp. 2726-2739
    • Alkondon, M.1    Pereira, E.F.R.2    Almeida, L.E.F.3    Randall, W.R.4    Albuquerque, E.X.5
  • 3
    • 0031410384 scopus 로고    scopus 로고
    • Choline is a selective agonist of α7 nicotinic acetylcholine receptors in the rat brain neurons
    • Alkondon M, Pereira EFR, Cortes WS, Maelicke A, Albuquerque EX. 1997. Choline is a selective agonist of α7 nicotinic acetylcholine receptors in the rat brain neurons. Eur J Neurosci 9:2734-2742.
    • (1997) Eur J Neurosci , vol.9 , pp. 2734-2742
    • Alkondon, M.1    Pereira, E.F.R.2    Cortes, W.S.3    Maelicke, A.4    Albuquerque, E.X.5
  • 4
    • 0027984340 scopus 로고
    • Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization
    • Alkondon M, Reinhardt S, Lobron C, Hermsen B, Maelicke A, Albuquerque EX. 1994. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization. J Pharmacol Exp Ther 271:494-506.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 494-506
    • Alkondon, M.1    Reinhardt, S.2    Lobron, C.3    Hermsen, B.4    Maelicke, A.5    Albuquerque, E.X.6
  • 5
    • 0028810623 scopus 로고
    • A nicotinic acetylcholine receptor subunit from insect brain forms a non-desensitising homo-oligomeric nicotinic acetylcholine receptor when expressed in Xenopus oocytes
    • Amar M, Thomas P, Wonnacott S, Lunt GG. 1995. A nicotinic acetylcholine receptor subunit from insect brain forms a non-desensitising homo-oligomeric nicotinic acetylcholine receptor when expressed in Xenopus oocytes. Neurosci Lett 199:107-110.
    • (1995) Neurosci Lett , vol.199 , pp. 107-110
    • Amar, M.1    Thomas, P.2    Wonnacott, S.3    Lunt, G.G.4
  • 6
    • 0027945601 scopus 로고
    • Neural mechanisms underlying nicotine dependence
    • Balfour DJ. 1994. Neural mechanisms underlying nicotine dependence. Addiction 89:1419-1423.
    • (1994) Addiction , vol.89 , pp. 1419-1423
    • Balfour, D.J.1
  • 8
    • 0035916261 scopus 로고    scopus 로고
    • Desensitization of neuronal nicotinic acetylcholine receptors conferred by n-terminal segments of the β2 subunit
    • Bohler S, Gay S, Bertrand S, Corringer PJ, Edelstein SJ, Changeux JP, Bertrand D. 2001. Desensitization of neuronal nicotinic acetylcholine receptors conferred by n-terminal segments of the β2 subunit. Biochemistry 40:2066-2074.
    • (2001) Biochemistry , vol.40 , pp. 2066-2074
    • Bohler, S.1    Gay, S.2    Bertrand, S.3    Corringer, P.J.4    Edelstein, S.J.5    Changeux, J.P.6    Bertrand, D.7
  • 9
    • 0031658642 scopus 로고    scopus 로고
    • Calcium modulation of activation and desensitization of nicotinic receptors from mouse brain
    • Booker TK, Smith KW, Dodrill C, Collins AC. 1998. Calcium modulation of activation and desensitization of nicotinic receptors from mouse brain. J Neurochem 71:1490-1500.
    • (1998) J Neurochem , vol.71 , pp. 1490-1500
    • Booker, T.K.1    Smith, K.W.2    Dodrill, C.3    Collins, A.C.4
  • 10
    • 0023159126 scopus 로고
    • Two distinct kinetic phases of desensitization of acetylcholine receptors of clonal rat PC12 cells
    • Boyd ND. 1987. Two distinct kinetic phases of desensitization of acetylcholine receptors of clonal rat PC12 cells. J Physiol 389:45-67.
    • (1987) J Physiol , vol.389 , pp. 45-67
    • Boyd, N.D.1
  • 11
    • 0032440954 scopus 로고    scopus 로고
    • Activation and inhibition of the human α7 nicotinic acetylcholine receptor by agonists
    • Briggs CA, McKenna DG. 1998. Activation and inhibition of the human α7 nicotinic acetylcholine receptor by agonists. Neuropharmacology 37:1095-1102.
    • (1998) Neuropharmacology , vol.37 , pp. 1095-1102
    • Briggs, C.A.1    McKenna, D.G.2
  • 12
    • 0032464957 scopus 로고    scopus 로고
    • Allosteric modulation of neuronal nicotinic acetylcholine receptors
    • Buisson B, Bertrand D. 1998. Allosteric modulation of neuronal nicotinic acetylcholine receptors. J Physiol (Paris) 92:89-100.
    • (1998) J Physiol (Paris) , vol.92 , pp. 89-100
    • Buisson, B.1    Bertrand, D.2
  • 13
    • 0036499938 scopus 로고    scopus 로고
    • Nicotine addiction: The possible role of functional upregulation
    • Buisson B, Bertrand D. 2002. Nicotine addiction: The possible role of functional upregulation. Trends Pharmacol Sci 23:130-136.
    • (2002) Trends Pharmacol Sci , vol.23 , pp. 130-136
    • Buisson, B.1    Bertrand, D.2
  • 14
    • 0024312649 scopus 로고
    • Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp
    • Cachelin AB, Colquhoun D. 1989. Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp. J Physiol (Lond) 415:159-188.
    • (1989) J Physiol (Lond) , vol.415 , pp. 159-188
    • Cachelin, A.B.1    Colquhoun, D.2
  • 15
    • 0026335951 scopus 로고
    • β subunits determine the time course of desensitization in rat α3 neuronal nicotinic acetylcholine receptors
    • Cachelin AB, Jaggi R. 1991. β subunits determine the time course of desensitization in rat α3 neuronal nicotinic acetylcholine receptors. Pflugers Arch 419:579-582.
    • (1991) Pflugers Arch , vol.419 , pp. 579-582
    • Cachelin, A.B.1    Jaggi, R.2
  • 18
    • 0029876527 scopus 로고    scopus 로고
    • Transmitter timecourse in the synaptic cleft: Its role in central synaptic function
    • Clements JD. 1996. Transmitter timecourse in the synaptic cleft: Its role in central synaptic function. Trends Neurosci 19:163-171.
    • (1996) Trends Neurosci , vol.19 , pp. 163-171
    • Clements, J.D.1
  • 19
    • 0028980450 scopus 로고
    • Regions of β2 and β4 responsible for differences between the steady state dose-response relationships of the α3β2 and α3β4 neuronal nicotinic receptors
    • Cohen BN, Figl A, Quick MW, Labarca C, Davidson N, Lester HA. 1995. Regions of β2 and β4 responsible for differences between the steady state dose-response relationships of the α3β2 and α3β4 neuronal nicotinic receptors. J Gen Physiol 105:745-764.
    • (1995) J Gen Physiol , vol.105 , pp. 745-764
    • Cohen, B.N.1    Figl, A.2    Quick, M.W.3    Labarca, C.4    Davidson, N.5    Lester, H.A.6
  • 20
    • 0028138676 scopus 로고
    • Sensitivity to nicotine and brain nicotinic receptors are altered by chronic nicotine and mecamylamine infusion
    • Collins AC, Luo Y, Selvaag S, Marks MJ. 1994. Sensitivity to nicotine and brain nicotinic receptors are altered by chronic nicotine and mecamylamine infusion. J Pharmacol Exp Ther 271:125-133.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 125-133
    • Collins, A.C.1    Luo, Y.2    Selvaag, S.3    Marks, M.J.4
  • 21
    • 0023856335 scopus 로고
    • Activation of ion channels in the frog end-plate by high concentrations of acetylcholine
    • Colquhoun D, Ogden DC. 1988. Activation of ion channels in the frog end-plate by high concentrations of acetylcholine. J Physiol (Lond) 395:131-159.
    • (1988) J Physiol (Lond) , vol.395 , pp. 131-159
    • Colquhoun, D.1    Ogden, D.C.2
  • 22
    • 0032032840 scopus 로고    scopus 로고
    • From muscle endplate to brain synapses: A short history of synapses and agonist-activated ion channels
    • Colquhoun D, Sakmann B. 1998. From muscle endplate to brain synapses: A short history of synapses and agonist-activated ion channels. Neuron 20:381-387.
    • (1998) Neuron , vol.20 , pp. 381-387
    • Colquhoun, D.1    Sakmann, B.2
  • 23
    • 0030627685 scopus 로고    scopus 로고
    • Pharmacology of neuronal nicotinic acetylcholine receptor subtypes
    • Colquhoun LM, Patrick JW. 1997. Pharmacology of neuronal nicotinic acetylcholine receptor subtypes. Adv Pharmacol 39:191-220.
    • (1997) Adv Pharmacol , vol.39 , pp. 191-220
    • Colquhoun, L.M.1    Patrick, J.W.2
  • 24
    • 0028940759 scopus 로고
    • Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions
    • Conroy WG, Berg DK. 1995. Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions. J Biol Chem 270:4424-4431.
    • (1995) J Biol Chem , vol.270 , pp. 4424-4431
    • Conroy, W.G.1    Berg, D.K.2
  • 26
    • 0031972835 scopus 로고    scopus 로고
    • Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors
    • Corringer PJ, Bertrand S, Bohler S, Edelstein SJ, Changeux JP, Bertrand D. 1998. Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors. J Neurosci 18:648-657.
    • (1998) J Neurosci , vol.18 , pp. 648-657
    • Corringer, P.J.1    Bertrand, S.2    Bohler, S.3    Edelstein, S.J.4    Changeux, J.P.5    Bertrand, D.6
  • 27
    • 0025605864 scopus 로고
    • A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX
    • Couturier S, Bertrand D, Matter JM, Hernandez MC, Bertrand S, Millar N, Valera S, Barkas T, Ballivet M. 1990. A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX. Neuron 5:847-856.
    • (1990) Neuron , vol.5 , pp. 847-856
    • Couturier, S.1    Bertrand, D.2    Matter, J.M.3    Hernandez, M.C.4    Bertrand, S.5    Millar, N.6    Valera, S.7    Barkas, T.8    Ballivet, M.9
  • 28
    • 0035986864 scopus 로고    scopus 로고
    • Prolonged stimulation of presynaptic nicotinic acetylcholine receptors in the rat interpeduncular nucleus has differential effects on transmitter release
    • to appear
    • Covernton PJO, Lester RAJ. 2002. Prolonged stimulation of presynaptic nicotinic acetylcholine receptors in the rat interpeduncular nucleus has differential effects on transmitter release. Int J Dev Neurosci, to appear.
    • (2002) Int J Dev Neurosci
    • Covernton, P.J.O.1    Lester, R.A.J.2
  • 29
    • 0032535583 scopus 로고    scopus 로고
    • Mammalian nicotinic receptors with α7 subunits that slowly desensitize and rapidly recover from alpha-bungarotoxin blockade
    • Cuevas J, Berg DK. 1998. Mammalian nicotinic receptors with α7 subunits that slowly desensitize and rapidly recover from alpha-bungarotoxin blockade. J Neurosci 18:10335-10344.
    • (1998) J Neurosci , vol.18 , pp. 10335-10344
    • Cuevas, J.1    Berg, D.K.2
  • 30
    • 0034659392 scopus 로고    scopus 로고
    • Two distinct classes of functional α7-containing nicotinic receptor on rat superior cervical ganglion neurons
    • Cuevas J, Roth AL, Berg DK. 2000. Two distinct classes of functional α7-containing nicotinic receptor on rat superior cervical ganglion neurons. J Physiol 525.3:735-746.
    • (2000) J Physiol , vol.5253 , pp. 735-746
    • Cuevas, J.1    Roth, A.L.2    Berg, D.K.3
  • 31
    • 0029953564 scopus 로고    scopus 로고
    • Molecular and cellular aspects of nicotine abuse
    • Dani JA, Heinemann S. 1996. Molecular and cellular aspects of nicotine abuse. Neuron 16:905-908.
    • (1996) Neuron , vol.16 , pp. 905-908
    • Dani, J.A.1    Heinemann, S.2
  • 32
    • 0034732322 scopus 로고    scopus 로고
    • Variations in desensitization of nicotinic acetylcholine receptors from hippocampus and midbrain dopamine areas
    • Dani JA, Radcliffe KA, Pidoplichko VI. 2000. Variations in desensitization of nicotinic acetylcholine receptors from hippocampus and midbrain dopamine areas. Eur J Pharmacol 393:31-38.
    • (2000) Eur J Pharmacol , vol.393 , pp. 31-38
    • Dani, J.A.1    Radcliffe, K.A.2    Pidoplichko, V.I.3
  • 33
    • 0023444655 scopus 로고
    • Activators of protein kinase C enhance acetylcholine receptor desensitization in sympathetic ganglion neurons
    • Downing JE, Role LW. 1987. Activators of protein kinase C enhance acetylcholine receptor desensitization in sympathetic ganglion neurons. Proc Natl Acad Sci USA 84:7739-7743.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7739-7743
    • Downing, J.E.1    Role, L.W.2
  • 34
    • 0031466434 scopus 로고    scopus 로고
    • Functional deactivation of the major neuronal nicotinic receptor caused by nicotine and a protein kinase-C dependent mechanism
    • Eilers H, Schaeffer E, Bickler PE, Forsayeth JR. 1997. Functional deactivation of the major neuronal nicotinic receptor caused by nicotine and a protein kinase-C dependent mechanism. Mol Pharmacol 52:1105-1112.
    • (1997) Mol Pharmacol , vol.52 , pp. 1105-1112
    • Eilers, H.1    Schaeffer, E.2    Bickler, P.E.3    Forsayeth, J.R.4
  • 35
    • 0035852933 scopus 로고    scopus 로고
    • α10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells
    • Elgoyhen AB, Vetter DE, Katz E, Rothlin CV, Heinemann SF, Boulter J. 2001. α10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells. Proc Natl Acad Sci USA 98:3501-3506.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3501-3506
    • Elgoyhen, A.B.1    Vetter, D.E.2    Katz, E.3    Rothlin, C.V.4    Heinemann, S.F.5    Boulter, J.6
  • 36
    • 0020003862 scopus 로고
    • Desensitization at the frog neuromuscular junction: A biphasic process
    • Feltz A, Trautmann A. 1982. Desensitization at the frog neuromuscular junction: A biphasic process. J Physiol (Lond) 322:257-272.
    • (1982) J Physiol (Lond) , vol.322 , pp. 257-272
    • Feltz, A.1    Trautmann, A.2
  • 38
    • 0030841113 scopus 로고    scopus 로고
    • Influence of subunit composition on desensitization of neuronal acetylcholine receptors at low concentrations of nicotine
    • Fenster CP, Rains MF, Noerager B, Quick MW, Lester RAJ. 1997. Influence of subunit composition on desensitization of neuronal acetylcholine receptors at low concentrations of nicotine. J Neurosci 17:5747-5759.
    • (1997) J Neurosci , vol.17 , pp. 5747-5759
    • Fenster, C.P.1    Rains, M.F.2    Noerager, B.3    Quick, M.W.4    Lester, R.A.J.5
  • 39
    • 0033563319 scopus 로고    scopus 로고
    • Upregulation of surface α4β2 nicotinic receptors is initiated by receptor desensitization following chronic exposure to nicotine
    • Fenster CP, Whitworth T, Quick MW, Lester RAJ. 1999b. Upregulation of surface α4β2 nicotinic receptors is initiated by receptor desensitization following chronic exposure to nicotine. J Neurosci 19:4804-4814.
    • (1999) J Neurosci , vol.19 , pp. 4804-4814
    • Fenster, C.P.1    Whitworth, T.2    Quick, M.W.3    Lester, R.A.J.4
  • 40
    • 0026593533 scopus 로고
    • A subtype of nicotinic cholinergic receptor in rat brain is composed of α4 and β2 subunits and is upregulated by chronic nicotine treatment
    • Flores CM, Rogers SW, Pabreza LA, Wolfe BB, Kellar KJ. 1992. A subtype of nicotinic cholinergic receptor in rat brain is composed of α4 and β2 subunits and is upregulated by chronic nicotine treatment. Mol Pharmacol 41:31-37.
    • (1992) Mol Pharmacol , vol.41 , pp. 31-37
    • Flores, C.M.1    Rogers, S.W.2    Pabreza, L.A.3    Wolfe, B.B.4    Kellar, K.J.5
  • 41
    • 0033922960 scopus 로고    scopus 로고
    • Subtype-selective inhibition of neuronal nicotinic acetylcholine receptors by cocaine is determined by the α4 and β4 subunits
    • Francis MM, Vazquez RW, Papke RL, Oswald RE. 2000. Subtype-selective inhibition of neuronal nicotinic acetylcholine receptors by cocaine is determined by the α4 and β4 subunits. Mol Pharmacol 58:109-119.
    • (2000) Mol Pharmacol , vol.58 , pp. 109-119
    • Francis, M.M.1    Vazquez, R.W.2    Papke, R.L.3    Oswald, R.E.4
  • 42
    • 0027509690 scopus 로고
    • A molecular scheme for the reaction between acetylcholine and nicotinic channels
    • Franke Ch, Parnas H, Hovav G, Dudel J. 1993. A molecular scheme for the reaction between acetylcholine and nicotinic channels. Biophys J 64:339-356.
    • (1993) Biophys J , vol.64 , pp. 339-356
    • Franke, Ch.1    Parnas, H.2    Hovav, G.3    Dudel, J.4
  • 43
    • 0032531893 scopus 로고    scopus 로고
    • Synaptic potentials medicated via α-Bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons
    • Frazier CJ, Buhler AV, Weiner JL, Dunwiddie TV. 1998. Synaptic potentials medicated via α-Bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons. J Neurosci 18:8228-8235.
    • (1998) J Neurosci , vol.18 , pp. 8228-8235
    • Frazier, C.J.1    Buhler, A.V.2    Weiner, J.L.3    Dunwiddie, T.V.4
  • 44
    • 0034595443 scopus 로고    scopus 로고
    • Inactivation of alpha 7 ACh receptors and activation of non-alpha 7 ACh receptors both contribute to long term potentiation induction in the hippocampal CA1 region
    • Fuji S, Ji Z, Sumikawa K. 2000. Inactivation of alpha 7 ACh receptors and activation of non-alpha 7 ACh receptors both contribute to long term potentiation induction in the hippocampal CA1 region. Neurosci Letts 286:134-138.
    • (2000) Neurosci Letts , vol.286 , pp. 134-138
    • Fuji, S.1    Ji, Z.2    Sumikawa, K.3
  • 45
    • 0029046913 scopus 로고
    • Neuronal nicotinic receptors: Molecular organization and regulations
    • Galzi JL, Changeux JP. 1995. Neuronal nicotinic receptors: Molecular organization and regulations. Neuropharmacology 34:563-582.
    • (1995) Neuropharmacology , vol.34 , pp. 563-582
    • Galzi, J.L.1    Changeux, J.P.2
  • 47
    • 0028177088 scopus 로고
    • Homomers of α8 and α7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties
    • Gerzanich V, Anand R, Lindstrom J. 1994. Homomers of α8 and α7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties. Mol Pharmacol 45:212-220.
    • (1994) Mol Pharmacol , vol.45 , pp. 212-220
    • Gerzanich, V.1    Anand, R.2    Lindstrom, J.3
  • 49
    • 0035879069 scopus 로고    scopus 로고
    • Long-lasting enhancement of glutamatergic synaptic transmission by acetylcholine contrasts with response adaptation after exposure to low-level nicotine
    • Girod R, Role LW. 2001. Long-lasting enhancement of glutamatergic synaptic transmission by acetylcholine contrasts with response adaptation after exposure to low-level nicotine. J Neurosci 21:5182-5190.
    • (2001) J Neurosci , vol.21 , pp. 5182-5190
    • Girod, R.1    Role, L.W.2
  • 50
    • 0030610921 scopus 로고    scopus 로고
    • Regulation of human α4β2 neuronal nicotine acetylcholine receptors by cholinergic channel ligand and second messenger pathways
    • Golpalakrishnan M, Molinari EJ, Sullivan J. 1997. Regulation of human α4β2 neuronal nicotine acetylcholine receptors by cholinergic channel ligand and second messenger pathways. Mol Pharmacol 52:524-534.
    • (1997) Mol Pharmacol , vol.52 , pp. 524-534
    • Golpalakrishnan, M.1    Molinari, E.J.2    Sullivan, J.3
  • 52
    • 0028080725 scopus 로고
    • Expression of alpha-bungarotoxin receptor subtypes in chick central nervous system during development
    • Gotti C, Moretti M, Longhi R, Briscini L, Balestra B, Clementi F. 1994. Expression of alpha-bungarotoxin receptor subtypes in chick central nervous system during development. J Recept Res 14:335-346.
    • (1994) J Recept Res , vol.14 , pp. 335-346
    • Gotti, C.1    Moretti, M.2    Longhi, R.3    Briscini, L.4    Balestra, B.5    Clementi, F.6
  • 54
    • 0026072627 scopus 로고
    • Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes: Role of the alpha subunit in agonist sensitivity and desensitization
    • Gross B, Ballivet M, Rungger D, Bertrand D. 1991. Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes: Role of the alpha subunit in agonist sensitivity and desensitization. Pflugers Arch 419:545-551.
    • (1991) Pflugers Arch , vol.419 , pp. 545-551
    • Gross, B.1    Ballivet, M.2    Rungger, D.3    Bertrand, D.4
  • 55
    • 0030466334 scopus 로고    scopus 로고
    • Activation of the protein phosphatase calcineurin during carbachol exposure decreases the extent of recovery from end-plate desensitization
    • Hardwick JC, Parsons RL. 1996. Activation of the protein phosphatase calcineurin during carbachol exposure decreases the extent of recovery from end-plate desensitization. J Neurophysiol 76:3609-3616.
    • (1996) J Neurophysiol , vol.76 , pp. 3609-3616
    • Hardwick, J.C.1    Parsons, R.L.2
  • 56
    • 0018790793 scopus 로고
    • Fast kinetic studies on the interaction of a fluorescent agonist with the membranebound acetylcholine receptor from Torpedo marmorata
    • Heidmann T, Changeux JP. 1979. Fast kinetic studies on the interaction of a fluorescent agonist with the membranebound acetylcholine receptor from Torpedo marmorata. Eur J Biochem 94:255-279.
    • (1979) Eur J Biochem , vol.94 , pp. 255-279
    • Heidmann, T.1    Changeux, J.P.2
  • 57
    • 0023875023 scopus 로고
    • 3H-nicotine binding on bovine adrenal chromaffin cells
    • 3H-nicotine binding on bovine adrenal chromaffin cells. J Neurosci 8:1436-1446.
    • (1988) J Neurosci , vol.8 , pp. 1436-1446
    • Higgins, L.S.1    Berg, D.K.2
  • 58
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to conduction and excitation in nerve
    • Hodgkin AL, Huxley AF. 1952. A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol (Lond) 117:500-544.
    • (1952) J Physiol (Lond) , vol.117 , pp. 500-544
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 59
    • 0030068020 scopus 로고    scopus 로고
    • Sustained nicotine exposure differentially affects α4β2 neuronal nicotinic receptors expressed in Xenopus oocytes
    • Hsu YN, Amin J, Weiss D, Wecker L. 1996. Sustained nicotine exposure differentially affects α4β2 neuronal nicotinic receptors expressed in Xenopus oocytes. J Neurochem 66:667-675.
    • (1996) J Neurochem , vol.66 , pp. 667-675
    • Hsu, Y.N.1    Amin, J.2    Weiss, D.3    Wecker, L.4
  • 60
    • 0030722148 scopus 로고    scopus 로고
    • Nicotine enhances the cyclic AMP-dependent protein kinase-mediated phosphorylation of alpha4 subunits of neuronal nicotinic receptors
    • Hsu YN, Edwards SC, Wecker L. 1997. Nicotine enhances the cyclic AMP-dependent protein kinase-mediated phosphorylation of alpha4 subunits of neuronal nicotinic receptors. J Neurochem 69:2427-2431.
    • (1997) J Neurochem , vol.69 , pp. 2427-2431
    • Hsu, Y.N.1    Edwards, S.C.2    Wecker, L.3
  • 61
    • 0022501502 scopus 로고
    • Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization
    • Huganir RL, Delcour AH, Greengard P, Hess GP. 1986. Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization. Nature 321:774-776.
    • (1986) Nature , vol.321 , pp. 774-776
    • Huganir, R.L.1    Delcour, A.H.2    Greengard, P.3    Hess, G.P.4
  • 62
    • 0025202331 scopus 로고
    • Regulation of neurotransmitter receptor desensitization by protein phosphorylation
    • Huganir RL, Greengard P. 1990. Regulation of neurotransmitter receptor desensitization by protein phosphorylation. Neuron 5:555-567.
    • (1990) Neuron , vol.5 , pp. 555-567
    • Huganir, R.L.1    Greengard, P.2
  • 63
    • 0027956268 scopus 로고
    • Agonist and antagonist effects of nicotine on chick neuronal receptors are defined by α and β subunits
    • Hussy N, Ballivet M, Bertrand D. 1994. Agonist and antagonist effects of nicotine on chick neuronal receptors are defined by α and β subunits. J Neurophysiol 72:1317-1326.
    • (1994) J Neurophysiol , vol.72 , pp. 1317-1326
    • Hussy, N.1    Ballivet, M.2    Bertrand, D.3
  • 64
    • 0027481608 scopus 로고
    • Modulation of acetylcholine-elicited currents in clonal rat phaeochromocytoma (PC12) cells by internal polyphosphates
    • Ifune CK, Steinbach JH. 1993. Modulation of acetylcholine-elicited currents in clonal rat phaeochromocytoma (PC12) cells by internal polyphosphates. J Physiol 463:431-447.
    • (1993) J Physiol , vol.463 , pp. 431-447
    • Ifune, C.K.1    Steinbach, J.H.2
  • 65
    • 0030025395 scopus 로고    scopus 로고
    • The impact of receptor desensitization on fast synaptic transmission
    • Jones MV, Westbrook GL. 1996. The impact of receptor desensitization on fast synaptic transmission. Trends Neurosci 19:96-101.
    • (1996) Trends Neurosci , vol.19 , pp. 96-101
    • Jones, M.V.1    Westbrook, G.L.2
  • 66
    • 0033485390 scopus 로고    scopus 로고
    • Nicotinic receptors in the brain: Correlating physiology with function
    • Jones S, Sudweeks S, Yakel JL. 1999. Nicotinic receptors in the brain: Correlating physiology with function. Trends Neurosci 22:555-561.
    • (1999) Trends Neurosci , vol.22 , pp. 555-561
    • Jones, S.1    Sudweeks, S.2    Yakel, J.L.3
  • 67
    • 84965075853 scopus 로고
    • A study of the desensitization produced by acetylcholine at the motor end-plate
    • Katz B, Thesleff S. 1957. A study of the desensitization produced by acetylcholine at the motor end-plate. J Physiol (Lond) 138:63-80.
    • (1957) J Physiol (Lond) , vol.138 , pp. 63-80
    • Katz, B.1    Thesleff, S.2
  • 68
    • 0034801191 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors containing alpha 7 subunits on rat cortical neurons do not undergo long-lasting inactivation even when up-regulated by chronic nicotine exposure
    • Kawai H, Berg DK. 2001. Nicotinic acetylcholine receptors containing alpha 7 subunits on rat cortical neurons do not undergo long-lasting inactivation even when up-regulated by chronic nicotine exposure. J Neurochem 78:1367-1378.
    • (2001) J Neurochem , vol.78 , pp. 1367-1378
    • Kawai, H.1    Berg, D.K.2
  • 69
    • 0032411214 scopus 로고    scopus 로고
    • Effects of chronic nicotine treatment on expression of diverse nicotinic acetylcholine receptor subtypes. 1. Dose- and time-dependent effects of nicotine treatment
    • Ke L, Eisenhour CM, Bencherif M, Lukas RJ. 1998. Effects of chronic nicotine treatment on expression of diverse nicotinic acetylcholine receptor subtypes. 1. Dose- and time-dependent effects of nicotine treatment. J Pharmacol Exp Ther 286:825-840.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 825-840
    • Ke, L.1    Eisenhour, C.M.2    Bencherif, M.3    Lukas, R.J.4
  • 70
    • 0030731765 scopus 로고    scopus 로고
    • Imaging of intracellular calcium during desensitization of nicotinic acetylcholine receptors of rat chromaffin cells
    • Khiroug L, Giniatullin R, Sokolova E, Talantova M, Nistri A. 1997. Imaging of intracellular calcium during desensitization of nicotinic acetylcholine receptors of rat chromaffin cells. Br J Pharmacol 122:1323-1332.
    • (1997) Br J Pharmacol , vol.122 , pp. 1323-1332
    • Khiroug, L.1    Giniatullin, R.2    Sokolova, E.3    Talantova, M.4    Nistri, A.5
  • 71
    • 0032053953 scopus 로고    scopus 로고
    • Recovery from desensitization of neuronal nicotinic acetylcholine receptors of rat chromaffin cells is modulated by intracellular calcium through distinct second messengers
    • Khiroug L, Sokolova E, Giniatullin R, Afzalov R, Nistri A. 1998. Recovery from desensitization of neuronal nicotinic acetylcholine receptors of rat chromaffin cells is modulated by intracellular calcium through distinct second messengers. J Neurosci 18:2458-2466.
    • (1998) J Neurosci , vol.18 , pp. 2458-2466
    • Khiroug, L.1    Sokolova, E.2    Giniatullin, R.3    Afzalov, R.4    Nistri, A.5
  • 72
    • 0037092335 scopus 로고    scopus 로고
    • Rat nicotinic ACh receptor α7 and β2 subunits co-assemble to form functional heteromeric nicotinic receptor channels
    • Khiroug SS, Harkness PC, Lamb PW, Sudweeks SN, Khiroug L, Millar NS, Yakel JL. 2002. Rat nicotinic ACh receptor α7 and β2 subunits co-assemble to form functional heteromeric nicotinic receptor channels. J Physiol 540:425-434.
    • (2002) J Physiol , vol.540 , pp. 425-434
    • Khiroug, S.S.1    Harkness, P.C.2    Lamb, P.W.3    Sudweeks, S.N.4    Khiroug, L.5    Millar, N.S.6    Yakel, J.L.7
  • 73
    • 0034732243 scopus 로고    scopus 로고
    • Acetylcholine receptor extracellular domain determines sensitivity to nicotine-induced inactivation
    • Kuryatov A, Olale FA, Choi C, Lindstrom J. 2000. Acetylcholine receptor extracellular domain determines sensitivity to nicotine-induced inactivation. Eur J Pharmacol 393:11-21.
    • (2000) Eur J Pharmacol , vol.393 , pp. 11-21
    • Kuryatov, A.1    Olale, F.A.2    Choi, C.3    Lindstrom, J.4
  • 74
    • 0028213259 scopus 로고
    • Time-dependent changes in central nicotinic acetylcholine channel kinetics in outside-out patches
    • Lester RAJ, Dani JA. 1994. Time-dependent changes in central nicotinic acetylcholine channel kinetics in outside-out patches. Neuropharmacol 33:27-34.
    • (1994) Neuropharmacol , vol.33 , pp. 27-34
    • Lester, R.A.J.1    Dani, J.A.2
  • 75
    • 0029144862 scopus 로고
    • Acetylcholine receptor desensitization induced by nicotine in rat medial habenula neurons
    • Lester RAJ, Dani JA. 1995. Acetylcholine receptor desensitization induced by nicotine in rat medial habenula neurons. J Neurophysiol 74:195-206.
    • (1995) J Neurophysiol , vol.74 , pp. 195-206
    • Lester, R.A.J.1    Dani, J.A.2
  • 76
    • 0023235042 scopus 로고
    • 3H] nicotine binding to putative high affinity receptor sites in rat brain
    • 3H] nicotine binding to putative high affinity receptor sites in rat brain. Mol Pharmacol 31:392-400.
    • (1987) Mol Pharmacol , vol.31 , pp. 392-400
    • Lippiello, P.M.1    Sears, S.B.2    Fernandes, K.G.3
  • 77
    • 0033508897 scopus 로고    scopus 로고
    • Actin filaments and the opposing actions of CaM kinase II and calcineurin in regulating α7-containing nicotinic receptors on chick ciliary ganglion neurons
    • Liu Q, Berg DK. 1999. Actin filaments and the opposing actions of CaM kinase II and calcineurin in regulating α7-containing nicotinic receptors on chick ciliary ganglion neurons. J Neurosci 19:10280-10288.
    • (1999) J Neurosci , vol.19 , pp. 10280-10288
    • Liu, Q.1    Berg, D.K.2
  • 78
    • 0032747785 scopus 로고    scopus 로고
    • 3H]γ-aminobutyric acid release from mouse brain synaptosomes is produced by subactivating concentrations of agonists
    • 3H]γ-aminobutyric acid release from mouse brain synaptosomes is produced by subactivating concentrations of agonists. J Pharmacol Exp Ther 291:1127-1134.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 1127-1134
    • Lu, Y.1    Marks, M.J.2    Collins, A.C.3
  • 79
    • 0025934097 scopus 로고
    • Both α- and β-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors
    • Luetje CW, Patrick JP. 1991. Both α- and β-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors. J Neurosci 11:837-845.
    • (1991) J Neurosci , vol.11 , pp. 837-845
    • Luetje, C.W.1    Patrick, J.P.2
  • 80
    • 0025969658 scopus 로고
    • Effects of chronic nicotinic ligand exposure on functional activity of nicotinic acetylcholine receptors expressed by cells of the PC12 rat pheochromocytoma or the TE671/RD human clonal line
    • Lukas RJ. 1991. Effects of chronic nicotinic ligand exposure on functional activity of nicotinic acetylcholine receptors expressed by cells of the PC12 rat pheochromocytoma or the TE671/RD human clonal line. J Neurochem 56:1134-1145.
    • (1991) J Neurochem , vol.56 , pp. 1134-1145
    • Lukas, R.J.1
  • 82
    • 0026738454 scopus 로고
    • A study of the bovine adrenal chromaffin nicotinic receptor using patch clamp and concentration-jump techniques
    • Maconochie DJ, Knight DE. 1992, A study of the bovine adrenal chromaffin nicotinic receptor using patch clamp and concentration-jump techniques. J Physiol 454:129-153.
    • (1992) J Physiol , vol.454 , pp. 129-153
    • Maconochie, D.J.1    Knight, D.E.2
  • 83
    • 0037075602 scopus 로고    scopus 로고
    • Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas
    • Mansvelder HD, Keath JR, McGehee DS. 2002. Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron 33:905-919.
    • (2002) Neuron , vol.33 , pp. 905-919
    • Mansvelder, H.D.1    Keath, J.R.2    McGehee, D.S.3
  • 84
    • 0023447035 scopus 로고
    • Cyclic AMP regulates the proportion of functional acetylcholine receptors on chicken ciliary ganglion neurons
    • Margiotta JF, Berg DK, Dionne VE. 1987. Cyclic AMP regulates the proportion of functional acetylcholine receptors on chicken ciliary ganglion neurons. Proc Natl Acad Sci USA 84:8155-8159.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8155-8159
    • Margiotta, J.F.1    Berg, D.K.2    Dionne, V.E.3
  • 85
    • 0020642784 scopus 로고
    • Effects of chronic nicotine infusion on tolerance development and nicotinic receptors
    • Marks MJ, Burch JB, Collins AC. 1983. Effects of chronic nicotine infusion on tolerance development and nicotinic receptors. J Pharmacol Exp Ther 226:817-825.
    • (1983) J Pharmacol Exp Ther , vol.226 , pp. 817-825
    • Marks, M.J.1    Burch, J.B.2    Collins, A.C.3
  • 86
    • 0027819295 scopus 로고
    • Downregulation of nicotine receptor function after chronic nicotine infusion
    • Marks MJ, Grady SR, Collins AC. 1993. Downregulation of nicotine receptor function after chronic nicotine infusion. J Pharmacol Exp Ther 266:1268-1276.
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 1268-1276
    • Marks, M.J.1    Grady, S.R.2    Collins, A.C.3
  • 89
    • 0025158403 scopus 로고
    • Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones
    • Mathie A, Colquhoun D, Cull-Candy SG. 1990. Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones. J Physiol 427:625-655.
    • (1990) J Physiol , vol.427 , pp. 625-655
    • Mathie, A.1    Colquhoun, D.2    Cull-Candy, S.G.3
  • 90
    • 0028965629 scopus 로고
    • Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons
    • McGehee DS, Role LW. 1995. Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu Rev Physiol 57:521-546.
    • (1995) Annu Rev Physiol , vol.57 , pp. 521-546
    • McGehee, D.S.1    Role, L.W.2
  • 91
    • 0033560926 scopus 로고    scopus 로고
    • Nicotinic receptor activation excites distinct subtypes of interneurons in the rat hippocampus
    • McQuiston AR, Madison DV. 1999. Nicotinic receptor activation excites distinct subtypes of interneurons in the rat hippocampus. J Neurosci 19:2887-2896.
    • (1999) J Neurosci , vol.19 , pp. 2887-2896
    • McQuiston, A.R.1    Madison, D.V.2
  • 92
    • 0034874246 scopus 로고    scopus 로고
    • Agonist regulation of rat α3β4 nicotinic acetylcholine receptors stably expressed in human embryonic kidney 293 cells
    • Meyer EL, Xiao Y, Kellar KJ. 2001. Agonist regulation of rat α3β4 nicotinic acetylcholine receptors stably expressed in human embryonic kidney 293 cells. Mol Pharmacol 60:568-576.
    • (2001) Mol Pharmacol , vol.60 , pp. 568-576
    • Meyer, E.L.1    Xiao, Y.2    Kellar, K.J.3
  • 93
    • 0034602138 scopus 로고    scopus 로고
    • Choline and acetylcholine have similar kinetic properties of activation and desensitization on the α7 nicotinic receptors in rat hippocampal neurons
    • Mike A, Castro NG, Albuquerque EX. 2000. Choline and acetylcholine have similar kinetic properties of activation and desensitization on the α7 nicotinic receptors in rat hippocampal neurons. Brain Res 882:155-168.
    • (2000) Brain Res , vol.882 , pp. 155-168
    • Mike, A.1    Castro, N.G.2    Albuquerque, E.X.3
  • 94
    • 0019314914 scopus 로고
    • Intracellular calcium and desensitization of acetylcholine receptors
    • Miledi R. 1980. Intracellular calcium and desensitization of acetylcholine receptors. Proc Roy Soc Lond B 209:447-452.
    • (1980) Proc Roy Soc Lond B , vol.209 , pp. 447-452
    • Miledi, R.1
  • 96
    • 0030471825 scopus 로고    scopus 로고
    • Phosphorylation of the predicted major intracellular domains of the rat and chick neuronal nicotinic acetylcholine receptor alpha7 subunit by cAMP-dependent protein kinase
    • Moss SJ, Mcdonald BJ, Rudhard Y, Schoepfer R. 1996. Phosphorylation of the predicted major intracellular domains of the rat and chick neuronal nicotinic acetylcholine receptor alpha7 subunit by cAMP-dependent protein kinase. Neuropharm 35:1023-1028.
    • (1996) Neuropharm , vol.35 , pp. 1023-1028
    • Moss, S.J.1    Mcdonald, B.J.2    Rudhard, Y.3    Schoepfer, R.4
  • 97
    • 0026580364 scopus 로고
    • Calcium influx through nicotinic receptor in rat central neurons: Its relevance to cellular regulation
    • Mulle C, Choquet D, Korn H, Changeux JP. 1992. Calcium influx through nicotinic receptor in rat central neurons: Its relevance to cellular regulation. Neuron 8:135-143.
    • (1992) Neuron , vol.8 , pp. 135-143
    • Mulle, C.1    Choquet, D.2    Korn, H.3    Changeux, J.P.4
  • 98
    • 0027304248 scopus 로고
    • Phosphorylation of rat brain nicotinic acetylcholine receptor by cAMP-dependent protein kinase in vitro
    • Nakayama H, Okuda H, Nakishima T. 1993. Phosphorylation of rat brain nicotinic acetylcholine receptor by cAMP-dependent protein kinase in vitro. Mol Brain Res 20:171-177.
    • (1993) Mol Brain Res , vol.20 , pp. 171-177
    • Nakayama, H.1    Okuda, H.2    Nakishima, T.3
  • 99
    • 0035163189 scopus 로고    scopus 로고
    • Functional properties of human nicotinic AChRs expressed by IMR-32 neuroblastoma cells resemble those of α3β4 AChRs expressed in permanently transfected HEK cells
    • Nelson ME, Wang F, Kuryatov A, Choi CH, Gerzanich V, Lindstrom J. 2001. Functional properties of human nicotinic AChRs expressed by IMR-32 neuroblastoma cells resemble those of α3β4 AChRs expressed in permanently transfected HEK cells. J Gen Physiol 118:563-582.
    • (2001) J Gen Physiol , vol.118 , pp. 563-582
    • Nelson, M.E.1    Wang, F.2    Kuryatov, A.3    Choi, C.H.4    Gerzanich, V.5    Lindstrom, J.6
  • 100
    • 0019985295 scopus 로고
    • Conformations of Torpedo acetylcholine receptor associated with ion transport and desensitization
    • Neubig RR, Boyd ND, Cohen JB. 1982. Conformations of Torpedo acetylcholine receptor associated with ion transport and desensitization. Biochemistry 21:3460-3467.
    • (1982) Biochemistry , vol.21 , pp. 3460-3467
    • Neubig, R.R.1    Boyd, N.D.2    Cohen, J.B.3
  • 101
    • 0024319944 scopus 로고
    • Desensitization of the nicotinic acetylcholine receptor: Molecular mechanisms and effect of modulators
    • Ochoa EL, Chattopadhyay A, McNamee MG. 1989. Desensitization of the nicotinic acetylcholine receptor: Molecular mechanisms and effect of modulators. Cell Mol Neurobiol 9:141-178.
    • (1989) Cell Mol Neurobiol , vol.9 , pp. 141-178
    • Ochoa, E.L.1    Chattopadhyay, A.2    McNamee, M.G.3
  • 102
    • 0030733496 scopus 로고    scopus 로고
    • Chronic nicotine exposure differentially affects the function of human α3, α4, and α7 neuronal nicotinic receptor subtypes
    • Olale F, Gerzanich V, Kuryatov A, Wang F, Lindstrom J. 1997. Chronic nicotine exposure differentially affects the function of human α3, α4, and α7 neuronal nicotinic receptor subtypes. J Pharmacol Exp Ther 283:675-683.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 675-683
    • Olale, F.1    Gerzanich, V.2    Kuryatov, A.3    Wang, F.4    Lindstrom, J.5
  • 103
    • 0024308955 scopus 로고
    • Properties of neuronal type acetylcholine receptors in voltage clamped mouse neuroblastoma cells
    • Oortgiesen M, Vijverberg HP. 1989. Properties of neuronal type acetylcholine receptors in voltage clamped mouse neuroblastoma cells. Neuroscience 31:169-179.
    • (1989) Neuroscience , vol.31 , pp. 169-179
    • Oortgiesen, M.1    Vijverberg, H.P.2
  • 104
    • 0030613669 scopus 로고    scopus 로고
    • Mice deficient in the α7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents
    • Orr-Urtreger A, Goldner FM, Saeki M, Lorenzo I, Goldberg L, De Biasi M, Dani JA, Patrick JW, Beaudet AL. 1997. Mice deficient in the α7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents. J Neurosci 17:9165-9171.
    • (1997) J Neurosci , vol.17 , pp. 9165-9171
    • Orr-Urtreger, A.1    Goldner, F.M.2    Saeki, M.3    Lorenzo, I.4    Goldberg, L.5    De Biasi, M.6    Dani, J.A.7    Patrick, J.W.8    Beaud, A.L.9
  • 105
    • 0029670737 scopus 로고    scopus 로고
    • Neuronal nicotinic α7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine
    • Palma E, Bertrand S, Binzoni T, Bertrand D. 1996. Neuronal nicotinic α7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine. J Physiol 491:151-161.
    • (1996) J Physiol , vol.491 , pp. 151-161
    • Palma, E.1    Bertrand, S.2    Binzoni, T.3    Bertrand, D.4
  • 106
    • 0034731873 scopus 로고    scopus 로고
    • α7 receptor-selective agonists and modes of α7 receptor activation
    • Papke RL, Meyer E, Nutter T, Uteshev VV.2000. α7 receptor-selective agonists and modes of α7 receptor activation. Eur J Pharmacol 393:179-195.
    • (2000) Eur J Pharmacol , vol.393 , pp. 179-195
    • Papke, R.L.1    Meyer, E.2    Nutter, T.3    Uteshev, V.V.4
  • 107
    • 0032533674 scopus 로고    scopus 로고
    • Long-term desensitization of nicotinic acetylcholine receptors is regulated via protein kinase A-mediated phosphorylation
    • Paradiso K, Brehm P. 1998. Long-term desensitization of nicotinic acetylcholine receptors is regulated via protein kinase A-mediated phosphorylation. J Neurosci 18:9227-9237.
    • (1998) J Neurosci , vol.18 , pp. 9227-9237
    • Paradiso, K.1    Brehm, P.2
  • 108
    • 0032438649 scopus 로고    scopus 로고
    • Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity
    • Parker MJ, Beck A, Luetje CW. 1998. Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity. Mol Pharmacol 54:1132-1139.
    • (1998) Mol Pharmacol , vol.54 , pp. 1132-1139
    • Parker, M.J.1    Beck, A.2    Luetje, C.W.3
  • 109
    • 0028136165 scopus 로고
    • Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover
    • Peng X, Gerzanich V, Anand R, Whiting PJ, Lindstrom J. 1994. Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover. Mol Pharmacol 46:523-530.
    • (1994) Mol Pharmacol , vol.46 , pp. 523-530
    • Peng, X.1    Gerzanich, V.2    Anand, R.3    Whiting, P.J.4    Lindstrom, J.5
  • 110
    • 0029416936 scopus 로고
    • 3H]epibatidine labels nicotinic receptors in rat brain: An autoradiographic study
    • 3H]epibatidine labels nicotinic receptors in rat brain: An autoradiographic study. J Pharmacol Exp Ther 275:1030-1034.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1030-1034
    • Perry, D.C.1    Kellar, K.J.2
  • 111
    • 0032588703 scopus 로고    scopus 로고
    • α3β4 subunit-containing nicotinic acetylcholine receptors dominate function in medial habenula neurons
    • Quick MW, Ceballos RM, Kasten M, McIntosh MJ, Lester RAJ. 1999. α3β4 subunit-containing nicotinic acetylcholine receptors dominate function in medial habenula neurons. Neuropharmacol 38:769-783.
    • (1999) Neuropharmacol , vol.38 , pp. 769-783
    • Quick, M.W.1    Ceballos, R.M.2    Kasten, M.3    McIntosh, M.J.4    Lester, R.A.J.5
  • 112
    • 0029670191 scopus 로고    scopus 로고
    • Functional contributions of α5 subunit to neuronal acetylcholine receptor channels
    • Ramirez-Latorre J, Yu CR, Qu X, Perin F, Karlin A, Role L. 1996. Functional contributions of α5 subunit to neuronal acetylcholine receptor channels. Nature 380:347-351.
    • (1996) Nature , vol.380 , pp. 347-351
    • Ramirez-Latorre, J.1    Yu, C.R.2    Qu, X.3    Perin, F.4    Karlin, A.5    Role, L.6
  • 113
    • 0032959307 scopus 로고    scopus 로고
    • Dependence of nicotinic acetylcholine receptor recovery from desensitization on the duration of agonist exposure
    • Reitstetter R, Lukas RJ, Gruener R. 1999. Dependence of nicotinic acetylcholine receptor recovery from desensitization on the duration of agonist exposure. J Pharmacol Exp Ther 289:656-660.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 656-660
    • Reitstetter, R.1    Lukas, R.J.2    Gruener, R.3
  • 115
    • 0021246985 scopus 로고
    • Substance P modulation of acetylcholine induced currents in embryonic chicken sympathetic and ciliary ganglion neurons
    • Role LW. 1984. Substance P modulation of acetylcholine induced currents in embryonic chicken sympathetic and ciliary ganglion neurons. Proc Natl Acad Sci USA 81:2924-2928.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 2924-2928
    • Role, L.W.1
  • 116
    • 0026874825 scopus 로고
    • Diversity of primary structure and function of neuronal nicotinic acetylcholine receptors
    • Role LW. 1992. Diversity of primary structure and function of neuronal nicotinic acetylcholine receptors. Curr Opin Neurobiol 2:254-262.
    • (1992) Curr Opin Neurobiol , vol.2 , pp. 254-262
    • Role, L.W.1
  • 117
    • 0028908290 scopus 로고
    • 3H]dopamine from rat striatal synaptosomes
    • 3H]dopamine from rat striatal synaptosomes. Neurosci Lett 189:171-175.
    • (1995) Neurosci Lett , vol.189 , pp. 171-175
    • Rowell, P.P.1
  • 118
    • 0031836531 scopus 로고    scopus 로고
    • Long-lasting inactivation of nicotinic receptor function in vitro by treatment with high concentrations of nicotine
    • Rowell PP, Duggan DS. 1998. Long-lasting inactivation of nicotinic receptor function in vitro by treatment with high concentrations of nicotine. Neuropharmacology 37:103-111.
    • (1998) Neuropharmacology , vol.37 , pp. 103-111
    • Rowell, P.P.1    Duggan, D.S.2
  • 119
    • 0028144806 scopus 로고
    • Characterization of nicotine-induced desensitization of evoked dopamine release from rat striatal synaptosomes
    • Rowell PP, Hillebrand JA. 1994. Characterization of nicotine-induced desensitization of evoked dopamine release from rat striatal synaptosomes. J Neurochem 63:561-569.
    • (1994) J Neurochem , vol.63 , pp. 561-569
    • Rowell, P.P.1    Hillebrand, J.A.2
  • 120
    • 0032951304 scopus 로고    scopus 로고
    • Ligand binding and activation of rat nicotinic α4β2 receptors stably expressed in HEK293 cells
    • Sabey K, Paradiso K, Zhang J, Steinbach JH. 1999. Ligand binding and activation of rat nicotinic α4β2 receptors stably expressed in HEK293 cells. Mol Pharmacol 55:58-66.
    • (1999) Mol Pharmacol , vol.55 , pp. 58-66
    • Sabey, K.1    Paradiso, K.2    Zhang, J.3    Steinbach, J.H.4
  • 121
    • 0019215162 scopus 로고
    • Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist
    • Sakmann B, Patlak J, Neher E. 1980. Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist. Nature 286:71-73.
    • (1980) Nature , vol.286 , pp. 71-73
    • Sakmann, B.1    Patlak, J.2    Neher, E.3
  • 122
    • 0027398069 scopus 로고
    • The diversity of neuronal acetylcholine receptors
    • Sargent PB. 1993. The diversity of neuronal acetylcholine receptors. Annu Rev Neurosci 16:403-443.
    • (1993) Annu Rev Neurosci , vol.16 , pp. 403-443
    • Sargent, P.B.1
  • 123
    • 0022274034 scopus 로고
    • 3H]acetylcholine recognition sites in brain by nicotinic cholinergic drugs
    • 3H]acetylcholine recognition sites in brain by nicotinic cholinergic drugs. J Neurochem 45:427-433.
    • (1985) J Neurochem , vol.45 , pp. 427-433
    • Schwartz, R.D.1    Kellar, K.J.2
  • 124
    • 0027518923 scopus 로고
    • Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium
    • Seguela P, Wadiche J, Dineley-Miller K, Dani JA, Patrick JW. 1993. Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium. J Neurosci 13:596-604.
    • (1993) J Neurosci , vol.13 , pp. 596-604
    • Seguela, P.1    Wadiche, J.2    Dineley-Miller, K.3    Dani, J.A.4    Patrick, J.W.5
  • 126
    • 0033819579 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor subunit mRNA expression and channel function in medial habenula neurons
    • Sheffield EB, Quick MW, Lester RAJ. 2000. Nicotinic acetylcholine receptor subunit mRNA expression and channel function in medial habenula neurons. Neuropharmacol 39:2591-2603.
    • (2000) Neuropharmacol , vol.39 , pp. 2591-2603
    • Sheffield, E.B.1    Quick, M.W.2    Lester, R.A.J.3
  • 127
    • 0025236771 scopus 로고
    • Human nicotinic acetylcholine receptor: The influence of second messengers on activation and desensitization
    • Siara J, Ruppersberg JP, Rüdel R. 1990. Human nicotinic acetylcholine receptor: The influence of second messengers on activation and desensitization. Pflügers Arch 415:701-706.
    • (1990) Pflügers Arch , vol.415 , pp. 701-706
    • Siara, J.1    Ruppersberg, J.P.2    Rüdel, R.3
  • 128
    • 0022457177 scopus 로고
    • Two components of carbamylcholine-induced loss of nicotinic acetylcholine receptor function in the neuronal cell line PC12
    • Simasko SM, Soares JR, Weiland GA, 1986. Two components of carbamylcholine-induced loss of nicotinic acetylcholine receptor function in the neuronal cell line PC12, Mol Pharmacol 30:6-12.
    • (1986) Mol Pharmacol , vol.30 , pp. 6-12
    • Simasko, S.M.1    Soares, J.R.2    Weiland, G.A.3
  • 129
    • 0030902282 scopus 로고    scopus 로고
    • Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour
    • Sivilotti LG, McNeil DK, Lewis TM, Nassar MA, Schoepfer R, Colquhoun D. 1997. Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour. J Physiol 500:123-138.
    • (1997) J Physiol , vol.500 , pp. 123-138
    • Sivilotti, L.G.1    McNeil, D.K.2    Lewis, T.M.3    Nassar, M.A.4    Schoepfer, R.5    Colquhoun, D.6
  • 130
    • 0018891065 scopus 로고
    • Substance P enhances cholinergic receptor desensitization in a clonal nerve cell line
    • Stallcup WB, Patrick J. 1980. Substance P enhances cholinergic receptor desensitization in a clonal nerve cell line. Proc Natl Acad Sci USA 77:634-638.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 634-638
    • Stallcup, W.B.1    Patrick, J.2
  • 131
    • 0028980028 scopus 로고
    • A missense mutation in the neuronal nicotinic acetylcholine receptor α4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy
    • Steinlein OK, Mulley JC, Propping P, Wallace RH, Phillips HA, Sutherland GR, Scheffer IE, Berkovic SF, 1995. A missense mutation in the neuronal nicotinic acetylcholine receptor α4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy. Nat Genet 11:201-213.
    • (1995) Nat Genet , vol.11 , pp. 201-213
    • Steinlein, O.K.1    Mulley, J.C.2    Propping, P.3    Wallace, R.H.4    Phillips, H.A.5    Sutherland, G.R.6    Scheffer, I.E.7    Berkovic, S.F.8
  • 132
    • 0026693501 scopus 로고
    • Phosphorylation of ligand-gated ion channels: A possible mode of synaptic plasticity
    • Swope SL, Moss SJ, Blackstone CD, Huganir RL. 1992. Phosphorylation of ligand-gated ion channels: A possible mode of synaptic plasticity. FASEB 6:2514-2523.
    • (1992) FASEB , vol.6 , pp. 2514-2523
    • Swope, S.L.1    Moss, S.J.2    Blackstone, C.D.3    Huganir, R.L.4
  • 133
    • 0028921479 scopus 로고
    • Acetylcholine receptor channel imaged in the open state
    • Unwin N. 1995. Acetylcholine receptor channel imaged in the open state. Nature 373:37-43.
    • (1995) Nature , vol.373 , pp. 37-43
    • Unwin, N.1
  • 134
    • 0030215397 scopus 로고    scopus 로고
    • α-bungarotoxinsensitive nicotinic responses in rat tuberomammillary neurons
    • Uteshev VV, Stevens DR, Haas HL. 1996. α-bungarotoxinsensitive nicotinic responses in rat tuberomammillary neurons. Pflügers Arch 432:607-613.
    • (1996) Pflügers Arch , vol.432 , pp. 607-613
    • Uteshev, V.V.1    Stevens, D.R.2    Haas, H.L.3
  • 135
    • 0026586188 scopus 로고
    • Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors
    • Vernino S, Amador M, Luetje CW, Patrick J, Dani JA. 1992. Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors. Neuron 8:127-134.
    • (1992) Neuron , vol.8 , pp. 127-134
    • Vernino, S.1    Amador, M.2    Luetje, C.W.3    Patrick, J.4    Dani, J.A.5
  • 136
    • 0028877288 scopus 로고
    • Differential desensitization properties of rat neuronal nicotinic acetylcholine receptor subunit combinations expressed in Xenopus laevis oocytes
    • Vibat CR, Lasalde JA, McNamee MG, Ochoa EL. 1995. Differential desensitization properties of rat neuronal nicotinic acetylcholine receptor subunit combinations expressed in Xenopus laevis oocytes. Cell Mol Neurobiol 15:411-425.
    • (1995) Cell Mol Neurobiol , vol.15 , pp. 411-425
    • Vibat, C.R.1    Lasalde, J.A.2    McNamee, M.G.3    Ochoa, E.L.4
  • 137
    • 0025499657 scopus 로고
    • Cyclic AMP-dependent phosphorylation of a neuronal acetylcholine receptor alpha-type subunit
    • Vijayaraghavan S, Schmid HA, Halvorsen SW, Berg DK. 1990. Cyclic AMP-dependent phosphorylation of a neuronal acetylcholine receptor alpha-type subunit. J Neurosci 10:3255-3262.
    • (1990) J Neurosci , vol.10 , pp. 3255-3262
    • Vijayaraghavan, S.1    Schmid, H.A.2    Halvorsen, S.W.3    Berg, D.K.4
  • 138
    • 0032528973 scopus 로고    scopus 로고
    • The α4 subunit of rat α4β2 nicotinic receptors is phosphorylated in vivo
    • Viseshakul N, Figl A, Lytle C, Cohen BN. 1998. The α4 subunit of rat α4β2 nicotinic receptors is phosphorylated in vivo. Mol Brain Res 59:100-104.
    • (1998) Mol Brain Res , vol.59 , pp. 100-104
    • Viseshakul, N.1    Figl, A.2    Lytle, C.3    Cohen, B.N.4
  • 139
    • 0024474491 scopus 로고
    • Distribution of α2, α3, α4, and β2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat
    • Wada E, Wada K, Boulter J, Deneris E, Heinemann S, Patrick J, Swanson LW. 1989. Distribution of α2, α3, α4, and β2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat. J Comp Neurol 284:314-335.
    • (1989) J Comp Neurol , vol.284 , pp. 314-335
    • Wada, E.1    Wada, K.2    Boulter, J.3    Deneris, E.4    Heinemann, S.5    Patrick, J.6    Swanson, L.W.7
  • 140
    • 0032582683 scopus 로고    scopus 로고
    • Chronic nicotine treatment up-regulates human α3β2 but not α3β4 acetylcholine receptors stably transfected in human embryonic kidney cells
    • Wang F, Nelson ME, Kuryatov A, Olale F, Cooper J, Keyser K, Lindstrom J. 1998. Chronic nicotine treatment up-regulates human α3β2 but not α3β4 acetylcholine receptors stably transfected in human embryonic kidney cells. J Biol Chem 273:28721-28732.
    • (1998) J Biol Chem , vol.273 , pp. 28721-28732
    • Wang, F.1    Nelson, M.E.2    Kuryatov, A.3    Olale, F.4    Cooper, J.5    Keyser, K.6    Lindstrom, J.7
  • 141
    • 0035150853 scopus 로고    scopus 로고
    • Cyclic AMP-dependent protein kinase (PKA) and protein kinase C phosphorylate sites in the amino acid sequence corresponding to the M3/M4 cytoplasmic domain of α4 neuronal nicotinic receptor subunits
    • Wecker L, Guo X, Rycerz AM, Edwards SC. 2001. Cyclic AMP-dependent protein kinase (PKA) and protein kinase C phosphorylate sites in the amino acid sequence corresponding to the M3/M4 cytoplasmic domain of α4 neuronal nicotinic receptor subunits. J Neurochem 76:711-720.
    • (2001) J Neurochem , vol.76 , pp. 711-720
    • Wecker, L.1    Guo, X.2    Rycerz, A.M.3    Edwards, S.C.4
  • 142
    • 0030602149 scopus 로고    scopus 로고
    • An amino acid exchange in the second transmembrane segment of a neuronal nicotinic receptor causes partial epilepsy by altering its desensitization kinetics
    • Wetland S, Witzemann V, Villarroel A, Propping P, Steinlein O. 1996. An amino acid exchange in the second transmembrane segment of a neuronal nicotinic receptor causes partial epilepsy by altering its desensitization kinetics. FEBS Lett 398:91-96.
    • (1996) FEBS Lett , vol.398 , pp. 91-96
    • Wetland, S.1    Witzemann, V.2    Villarroel, A.3    Propping, P.4    Steinlein, O.5
  • 144
    • 0031780511 scopus 로고    scopus 로고
    • Agonistinduced up-regulation of α4β2 nicotinic acetylcholine receptors in M10 cells: Pharmacological and spatial definition
    • Whiteaker P, Sharples CGV, Wonnacott S. 1998. Agonistinduced up-regulation of α4β2 nicotinic acetylcholine receptors in M10 cells: Pharmacological and spatial definition. Mol Pharmacol 53:950-962.
    • (1998) Mol Pharmacol , vol.53 , pp. 950-962
    • Whiteaker, P.1    Sharples, C.G.V.2    Wonnacott, S.3
  • 145
    • 0023751963 scopus 로고
    • Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies
    • Whiting PJ, Lindstrom JM. 1988. Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies. J Neurosci 8:3395-3404.
    • (1988) J Neurosci , vol.8 , pp. 3395-3404
    • Whiting, P.J.1    Lindstrom, J.M.2
  • 146
    • 0035970016 scopus 로고    scopus 로고
    • Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine-accessibility method
    • Wilson G, Karlin A. 2001. Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine-accessibility method. Proc Natl Acad Sci USA 98:1241-1248.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1241-1248
    • Wilson, G.1    Karlin, A.2
  • 147
    • 84973712244 scopus 로고
    • Brain nicotine binding sites
    • Wonnacott S. 1987. Brain nicotine binding sites. Hum Toxicol 6:343-353.
    • (1987) Hum Toxicol , vol.6 , pp. 343-353
    • Wonnacott, S.1
  • 148
    • 0031595642 scopus 로고    scopus 로고
    • Rat β3/β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: Pharmacology of ligand binding and function
    • Xiao Y, Meyer EL, Thompson JM, Surin A, Wroblewski J, Kellar KJ. 1998. Rat β3/β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: Pharmacology of ligand binding and function. Mol Pharmacol 54:322-333.
    • (1998) Mol Pharmacol , vol.54 , pp. 322-333
    • Xiao, Y.1    Meyer, E.L.2    Thompson, J.M.3    Surin, A.4    Wroblewski, J.5    Kellar, K.J.6
  • 150
    • 0028178802 scopus 로고
    • Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels
    • Zhang ZW, Vijayaraghavan S, Berg DK. 1994. Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels. Neuron 12:167-177.
    • (1994) Neuron , vol.12 , pp. 167-177
    • Zhang, Z.W.1    Vijayaraghavan, S.2    Berg, D.K.3
  • 151
    • 0030930815 scopus 로고    scopus 로고
    • Nicotinic acetylcholine sensitivity of rat petrosal sensory neurons in dissociated cell culture
    • Zhong H, Nurse CA. 1997. Nicotinic acetylcholine sensitivity of rat petrosal sensory neurons in dissociated cell culture. Brain Res 766:153-161.
    • (1997) Brain Res , vol.766 , pp. 153-161
    • Zhong, H.1    Nurse, C.A.2
  • 152
    • 0035196324 scopus 로고    scopus 로고
    • Endogenous nicotinic cholinergic activity regulates dopamine release in the striatum
    • Zhou FM, Liang Y, Dani JA. 2001. Endogenous nicotinic cholinergic activity regulates dopamine release in the striatum. Nat Neurosci 4:1224-1229.
    • (2001) Nat Neurosci , vol.4 , pp. 1224-1229
    • Zhou, F.M.1    Liang, Y.2    Dani, J.A.3
  • 153
    • 0002618929 scopus 로고    scopus 로고
    • Distribution of cholinergic neurons in the mammalian brain with special reference to their relationship with neuronal nicotinic acetylcholine receptors
    • Clementi F, Fornasari D, Gotti C, editors. Berlin: Springer
    • Zoli M. 2000. Distribution of cholinergic neurons in the mammalian brain with special reference to their relationship with neuronal nicotinic acetylcholine receptors. In: Clementi F, Fornasari D, Gotti C, editors. Neuronal Nicotinic Receptors. Berlin: Springer, p 13-30.
    • (2000) Neuronal Nicotinic Receptors , pp. 13-30
    • Zoli, M.1
  • 154
    • 0345131682 scopus 로고    scopus 로고
    • Identification of four classes of brain nicotinic receptors using β2 mutant mice
    • Zoli M, Lena C, Picciotto MR, Changeux JP. 1998. Identification of four classes of brain nicotinic receptors using β2 mutant mice. J Neurosci 18:4461-4472.
    • (1998) J Neurosci , vol.18 , pp. 4461-4472
    • Zoli, M.1    Lena, C.2    Picciotto, M.R.3    Changeux, J.P.4
  • 155
    • 0027049313 scopus 로고
    • Nicotinic acetylcholine currents in cultured postnatal rat hippocampal neurons
    • Zorumski CF, Thio LL, Isenberg KE, Clifford DB. 1992. Nicotinic acetylcholine currents in cultured postnatal rat hippocampal neurons. Mol Pharmacol 41:931-936.
    • (1992) Mol Pharmacol , vol.41 , pp. 931-936
    • Zorumski, C.F.1    Thio, L.L.2    Isenberg, K.E.3    Clifford, D.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.