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Volumn 11, Issue 8, 1999, Pages 2689-2696

An autoradiographic study of the distribution of binding sites for the novel α7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain

Author keywords

bungarotoxin; Acetylcholine; Autoradiogaphy; MLA; Nicotine; Receptor

Indexed keywords

BUNGAROTOXIN; IODINE 125; METHYLLYCACONITINE; NICOTINE; NICOTINIC RECEPTOR; TRITIUM;

EID: 0032818891     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00685.x     Document Type: Article
Times cited : (121)

References (36)
  • 2
    • 0027382077 scopus 로고
    • Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons 1. Pharmacological and functional evidence for distinct structural subtypes
    • Alkondon, M. & Albuquerque, E.X. (1993) Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons 1. Pharmacological and functional evidence for distinct structural subtypes. J. Pharm. Exp. Ther., 265, 1455-1473.
    • (1993) J. Pharm. Exp. Ther. , vol.265 , pp. 1455-1473
    • Alkondon, M.1    Albuquerque, E.X.2
  • 4
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant and the concentration of inhibitor which cause 50 percent of an enzymatic reaction
    • Cheng, Y.-C. & Prusoff, W.H. (1973) Relationship between the inhibition constant and the concentration of inhibitor which cause 50 percent of an enzymatic reaction. Biochem. Pharmacol., 22, 3099-3108.
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 3099-3108
    • Cheng, Y.-C.1    Prusoff, W.H.2
  • 6
    • 0027971745 scopus 로고
    • Rapid and efficient isolation of the nicotinic receptor antagonist methyllycaconitine from delphinium - Assignment of the methylsuccinimide absolute stereochemistry as S
    • Coates, P.A., Blagbrough, I.S., Hardick, D.J., Rowan, M.G., Wonnacott, S. & Potter, B.V.L. (1994) Rapid and efficient isolation of the nicotinic receptor antagonist methyllycaconitine from delphinium - assignment of the methylsuccinimide absolute stereochemistry as S. Tetrahedron. Lett., 35, 8701-8704.
    • (1994) Tetrahedron. Lett. , vol.35 , pp. 8701-8704
    • Coates, P.A.1    Blagbrough, I.S.2    Hardick, D.J.3    Rowan, M.G.4    Wonnacott, S.5    Potter, B.V.L.6
  • 7
    • 0029595252 scopus 로고
    • An HPLC assay for the norditerpenoid alkaloid methyllycaconitine, a potent nicotinic acetylcholine receptor antagonist
    • Coates, P.A., Blagbrough, I.S., Lewis, T., Potter, B.V.L. & Rowan, M.G. (1995) An HPLC assay for the norditerpenoid alkaloid methyllycaconitine, a potent nicotinic acetylcholine receptor antagonist. J. Pharm. Biomed. Anal., 13, 1541-1544.
    • (1995) J. Pharm. Biomed. Anal. , vol.13 , pp. 1541-1544
    • Coates, P.A.1    Blagbrough, I.S.2    Lewis, T.3    Potter, B.V.L.4    Rowan, M.G.5
  • 8
    • 0025605864 scopus 로고
    • A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX
    • Couturier, S., Bertrand, D., Matter, J.-M., Hernandez, M.-C., Bertrand, S., Millar, N., Valera, S., Barkas, T. & Ballivet, M. (1990) A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX. Neuron, 5, 847-856.
    • (1990) Neuron , vol.5 , pp. 847-856
    • Couturier, S.1    Bertrand, D.2    Matter, J.-M.3    Hernandez, M.-C.4    Bertrand, S.5    Millar, N.6    Valera, S.7    Barkas, T.8    Ballivet, M.9
  • 9
    • 0032535583 scopus 로고    scopus 로고
    • Mammalian nicotinic receptors with α7 subunits that slowly desensitize and rapidly recover from α-bungarotoxin blockade
    • Cuevas, J. & Berg, D.K. (1998) Mammalian nicotinic receptors with α7 subunits that slowly desensitize and rapidly recover from α-bungarotoxin blockade. J. Neurosci., 18, 10335-10344.
    • (1998) J. Neurosci. , vol.18 , pp. 10335-10344
    • Cuevas, J.1    Berg, D.K.2
  • 11
    • 0027772476 scopus 로고
    • Chimeric nicotinic serotonergic receptor combines distinct ligand-binding and channel specificities
    • Eisele, J.L., Bertrand, S., Galzi, J.L., Devillersthiery, A., Changeux, J.P. & Bertrand, D. (1993) Chimeric nicotinic serotonergic receptor combines distinct ligand-binding and channel specificities. Nature, 366, 479-483.
    • (1993) Nature , vol.366 , pp. 479-483
    • Eisele, J.L.1    Bertrand, S.2    Galzi, J.L.3    Devillersthiery, A.4    Changeux, J.P.5    Bertrand, D.6
  • 12
    • 0028171296 scopus 로고
    • α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells
    • Elgoyhen, A.B., Johnson, D.S., Boulter, J., Vetter, D.E. & Heinemann, S. (1994) α9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell, 79, 705-715.
    • (1994) Cell , vol.79 , pp. 705-715
    • Elgoyhen, A.B.1    Johnson, D.S.2    Boulter, J.3    Vetter, D.E.4    Heinemann, S.5
  • 13
    • 0026593533 scopus 로고
    • A subtype of nicotinic cholinergic receptor in rat brain is composed of α4-subunit and β2-subunit and is upregulated by chronic nicotine treatment
    • Flores, C.M., Gogers, S.W., Pabreza, L.A., Wolfe, B.B. & Kellar, K.J. (1992) A subtype of nicotinic cholinergic receptor in rat brain is composed of α4-subunit and β2-subunit and is upregulated by chronic nicotine treatment. Mol. Pharmacol., 41, 31-37.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 31-37
    • Flores, C.M.1    Gogers, S.W.2    Pabreza, L.A.3    Wolfe, B.B.4    Kellar, K.J.5
  • 14
    • 0021879860 scopus 로고
    • Quantitative film autoradiography for tritium-methodological considerations
    • Geary, W.A., Toga, A.W. & Wooten, G.F. (1985) Quantitative film autoradiography for tritium-methodological considerations. Brain Res., 337, 99-108.
    • (1985) Brain Res. , vol.337 , pp. 99-108
    • Geary, W.A.1    Toga, A.W.2    Wooten, G.F.3
  • 15
    • 0032521360 scopus 로고    scopus 로고
    • Glutamate and GABA release are enhanced by different subtypes of presynaptic nicotinic receptors in the lateral geniculate nucleus
    • Guo, J.Z., Tredway, T.L. & Chiappinelli, V.A. (1998) Glutamate and GABA release are enhanced by different subtypes of presynaptic nicotinic receptors in the lateral geniculate nucleus J. Neurosci., 18, 1963-1969.
    • (1998) J. Neurosci. , vol.18 , pp. 1963-1969
    • Guo, J.Z.1    Tredway, T.L.2    Chiappinelli, V.A.3
  • 16
    • 0030474553 scopus 로고    scopus 로고
    • Nudicauline and elatine as potent norditerpenoid ligands at the rat neuronal α-bungarotoxin binding sites: Importance of the 2-(methylsuccinimido) benzoyl moiety for neuronal nicotinic acetylcholine receptor binding
    • Hardick, D.J., Blagbrough, I.S., Cooper, G., Potter, B.V.L., Critchley, T. & Wonnacott, S. (1996a) Nudicauline and elatine as potent norditerpenoid ligands at the rat neuronal α-bungarotoxin binding sites: Importance of the 2-(methylsuccinimido) benzoyl moiety for neuronal nicotinic acetylcholine receptor binding. J. Med. Chem., 39, 4860-4866.
    • (1996) J. Med. Chem. , vol.39 , pp. 4860-4866
    • Hardick, D.J.1    Blagbrough, I.S.2    Cooper, G.3    Potter, B.V.L.4    Critchley, T.5    Wonnacott, S.6
  • 17
    • 0030018218 scopus 로고    scopus 로고
    • Isotopic enrichment by asymmetric deuteration. An investigation of the synthesis of deuterated (S)-(-)-methylsuccinic acids from itaconic acid
    • Hardick, D.J., Blagbrough, I.S. & Potter, B.V.L. (1996b) Isotopic enrichment by asymmetric deuteration. An investigation of the synthesis of deuterated (S)-(-)-methylsuccinic acids from itaconic acid. J. Am. Chem. Soc., 118, 5897-5903.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 5897-5903
    • Hardick, D.J.1    Blagbrough, I.S.2    Potter, B.V.L.3
  • 18
    • 0031450275 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors as targets for drug discovery
    • Holladay, M.W., Dart, M.J. & Lynch, J.K. (1997) Neuronal nicotinic acetylcholine receptors as targets for drug discovery. J. Med. Chem., 40, 4169-4194.
    • (1997) J. Med. Chem. , vol.40 , pp. 4169-4194
    • Holladay, M.W.1    Dart, M.J.2    Lynch, J.K.3
  • 19
    • 0023845177 scopus 로고
    • Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems
    • MacAllan, D.R.E., Lunt, G.G., Wonnacott, S., Swanson, K.L., Rapoport, H. & Albuquerque, E.X. (1988) Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems. FEBS Lett., 226, 357-363.
    • (1988) FEBS Lett. , vol.226 , pp. 357-363
    • MacAllan, D.R.E.1    Lunt, G.G.2    Wonnacott, S.3    Swanson, K.L.4    Rapoport, H.5    Albuquerque, E.X.6
  • 20
    • 0023029997 scopus 로고
    • Nicotinic binding sites in rat and mouse brain: Comparison of acetylcholine, nicotine and αBgt
    • Marks, M.J., Stitzel, J.A., Romm, E., Wehner, J.M. & Collins, A.C. (1986) Nicotinic binding sites in rat and mouse brain: Comparison of acetylcholine, nicotine and αBgt. Mol. Pharmacol., 30, 427-436.
    • (1986) Mol. Pharmacol. , vol.30 , pp. 427-436
    • Marks, M.J.1    Stitzel, J.A.2    Romm, E.3    Wehner, J.M.4    Collins, A.C.5
  • 23
  • 24
    • 0029670737 scopus 로고    scopus 로고
    • Neuronal α7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine
    • Palma, E., Bertrand, S., Binzoni, T. & Bertrand, D. (1996). Neuronal α7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine. J. Physiol. (Lond.), 491, 151-161.
    • (1996) J. Physiol. (Lond.) , vol.491 , pp. 151-161
    • Palma, E.1    Bertrand, S.2    Binzoni, T.3    Bertrand, D.4
  • 25
    • 0024327212 scopus 로고
    • An autoradiographic analysis of cholinergic receptors in mouse brain
    • Pauly, J.R., Marks, M.J., Gross, S.D. & Collins, A.C. (1989) An autoradiographic analysis of cholinergic receptors in mouse brain. Brain Res. Bull., 22, 453-459.
    • (1989) Brain Res. Bull. , vol.22 , pp. 453-459
    • Pauly, J.R.1    Marks, M.J.2    Gross, S.D.3    Collins, A.C.4
  • 26
    • 0025943470 scopus 로고
    • An autoradiographic analysis of cholinergic receptors in mouse brain after chronic nicotine treatment
    • Pauly, J.R., Marks, M.J., Gross, S.D. & Collins, A.C. (1991) An autoradiographic analysis of cholinergic receptors in mouse brain after chronic nicotine treatment. J. Pharm. Exp. Ther., 258, 1-10.
    • (1991) J. Pharm. Exp. Ther. , vol.258 , pp. 1-10
    • Pauly, J.R.1    Marks, M.J.2    Gross, S.D.3    Collins, A.C.4
  • 28
    • 0030175612 scopus 로고    scopus 로고
    • Nicotinic receptors in the development and modulation of CNS synapses
    • Role, L.W. & Berg, D.K. (1996) Nicotinic receptors in the development and modulation of CNS synapses. Neuron, 16, 1077-1085.
    • (1996) Neuron , vol.16 , pp. 1077-1085
    • Role, L.W.1    Berg, D.K.2
  • 30
    • 0025308827 scopus 로고
    • Brain α-bungarotoxin-binding protein cDNAs and mABs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily
    • Schoepfer, R., Conroy, W.G., Whiting, P., Gore, M. & Lindstrom, J. (1990) Brain α-bungarotoxin-binding protein cDNAs and mABs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily. Neuron, 5, 35-48.
    • (1990) Neuron , vol.5 , pp. 35-48
    • Schoepfer, R.1    Conroy, W.G.2    Whiting, P.3    Gore, M.4    Lindstrom, J.5
  • 31
    • 0027518923 scopus 로고
    • Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium
    • Seguela, P., Wadiche, J., Dineley-Miller, K., Dani, J.A. & Patrick, J.W. (1993) Molecular cloning, functional properties, and distribution of rat brain α7: a nicotinic cation channel highly permeable to calcium. J. Neurosci., 13, 596-604.
    • (1993) J. Neurosci. , vol.13 , pp. 596-604
    • Seguela, P.1    Wadiche, J.2    Dineley-Miller, K.3    Dani, J.A.4    Patrick, J.W.5
  • 32
    • 0000158143 scopus 로고
    • Methyllycaconitine: A new probe that discriminates between nicotinic acetylcholine receptor subclasses
    • Wonnacott, S., Albuquerque, E.X. & Bertrand, D. (1993) Methyllycaconitine: a new probe that discriminates between nicotinic acetylcholine receptor subclasses. Meth. Neurosci., 12, 263-275.
    • (1993) Meth. Neurosci. , vol.12 , pp. 263-275
    • Wonnacott, S.1    Albuquerque, E.X.2    Bertrand, D.3
  • 33
    • 0032525992 scopus 로고    scopus 로고
    • Functional contribution of the α7 subunit to multiple subtypes of nicotinic receptors in embryonic sympathetic neurons
    • Yu, C. & Role, L.W. (1998a) Functional contribution of the α7 subunit to multiple subtypes of nicotinic receptors in embryonic sympathetic neurons. J. Physiol. (Lond.), 509, 651-655.
    • (1998) J. Physiol. (Lond.) , vol.509 , pp. 651-655
    • Yu, C.1    Role, L.W.2
  • 34
    • 0032526022 scopus 로고    scopus 로고
    • Functional contribution of the α5 subunit to neuronal nicotinic channels expressed by chick sympathetic ganglion neurons
    • Yu, C. & Role, L.W. (1998b) Functional contribution of the α5 subunit to neuronal nicotinic channels expressed by chick sympathetic ganglion neurons. J. Physiol. (Lond.), 509, 667-681.
    • (1998) J. Physiol. (Lond.) , vol.509 , pp. 667-681
    • Yu, C.1    Role, L.W.2
  • 35
    • 0029972573 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in separate brain regions exhibit different affinities for methyllycaconitine
    • Yum, L., Wolf, K.M. & Chiappinelli, V.A. (1996) Nicotinic acetylcholine receptors in separate brain regions exhibit different affinities for methyllycaconitine. Neuroscience, 72, 545-555.
    • (1996) Neuroscience , vol.72 , pp. 545-555
    • Yum, L.1    Wolf, K.M.2    Chiappinelli, V.A.3
  • 36
    • 0345131682 scopus 로고    scopus 로고
    • Identification of four classes of brain nicotinic receptors using β2 mutant mice
    • Zoli, M., Lena, C., Picciotto, M.R. & Changeux, J.P. (1998) Identification of four classes of brain nicotinic receptors using β2 mutant mice. J. Neurosci., 18, 4461-4472.
    • (1998) J. Neurosci. , vol.18 , pp. 4461-4472
    • Zoli, M.1    Lena, C.2    Picciotto, M.R.3    Changeux, J.P.4


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