-
1
-
-
0005994352
-
Properties of neuronal nicotinic acetylcholine receptors: Pharmacological characterization and modulation of synaptic function
-
Albuquerque, E.X., Alkondon, M., Pereira, E.F.R., Castro, N.G., Schratlenholz, A., Barbosa, C.T.F., Bonfante-Cabarcas, R., Aracava, Y., Eisenberg, H.M. & Maelicke, A. (1997) Properties of neuronal nicotinic acetylcholine receptors: Pharmacological characterization and modulation of synaptic function. J. Pharm. Exp. Ther., 280, 1117-1136.
-
(1997)
J. Pharm. Exp. Ther.
, vol.280
, pp. 1117-1136
-
-
Albuquerque, E.X.1
Alkondon, M.2
Pereira, E.F.R.3
Castro, N.G.4
Schratlenholz, A.5
Barbosa, C.T.F.6
Bonfante-Cabarcas, R.7
Aracava, Y.8
Eisenberg, H.M.9
Maelicke, A.10
-
2
-
-
0027382077
-
Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons 1. Pharmacological and functional evidence for distinct structural subtypes
-
Alkondon, M. & Albuquerque, E.X. (1993) Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons 1. Pharmacological and functional evidence for distinct structural subtypes. J. Pharm. Exp. Ther., 265, 1455-1473.
-
(1993)
J. Pharm. Exp. Ther.
, vol.265
, pp. 1455-1473
-
-
Alkondon, M.1
Albuquerque, E.X.2
-
3
-
-
0028149403
-
Acylation of lycoctonine: Semi-synthesis of inuline, delsemine analogues and methyllycaconitine
-
Blagbrough, I.S., Coates, P.A., Hardick, D.J., Lewis, T., Rowan, M.G., Wonnacott, S. & Potter, B.V.L. (1994) Acylation of lycoctonine: semi-synthesis of inuline, delsemine analogues and methyllycaconitine. Tetrahedron. Lett., 35, 8705-8708.
-
(1994)
Tetrahedron. Lett.
, vol.35
, pp. 8705-8708
-
-
Blagbrough, I.S.1
Coates, P.A.2
Hardick, D.J.3
Lewis, T.4
Rowan, M.G.5
Wonnacott, S.6
Potter, B.V.L.7
-
4
-
-
0015861774
-
Relationship between the inhibition constant and the concentration of inhibitor which cause 50 percent of an enzymatic reaction
-
Cheng, Y.-C. & Prusoff, W.H. (1973) Relationship between the inhibition constant and the concentration of inhibitor which cause 50 percent of an enzymatic reaction. Biochem. Pharmacol., 22, 3099-3108.
-
(1973)
Biochem. Pharmacol.
, vol.22
, pp. 3099-3108
-
-
Cheng, Y.-C.1
Prusoff, W.H.2
-
6
-
-
0027971745
-
Rapid and efficient isolation of the nicotinic receptor antagonist methyllycaconitine from delphinium - Assignment of the methylsuccinimide absolute stereochemistry as S
-
Coates, P.A., Blagbrough, I.S., Hardick, D.J., Rowan, M.G., Wonnacott, S. & Potter, B.V.L. (1994) Rapid and efficient isolation of the nicotinic receptor antagonist methyllycaconitine from delphinium - assignment of the methylsuccinimide absolute stereochemistry as S. Tetrahedron. Lett., 35, 8701-8704.
-
(1994)
Tetrahedron. Lett.
, vol.35
, pp. 8701-8704
-
-
Coates, P.A.1
Blagbrough, I.S.2
Hardick, D.J.3
Rowan, M.G.4
Wonnacott, S.5
Potter, B.V.L.6
-
7
-
-
0029595252
-
An HPLC assay for the norditerpenoid alkaloid methyllycaconitine, a potent nicotinic acetylcholine receptor antagonist
-
Coates, P.A., Blagbrough, I.S., Lewis, T., Potter, B.V.L. & Rowan, M.G. (1995) An HPLC assay for the norditerpenoid alkaloid methyllycaconitine, a potent nicotinic acetylcholine receptor antagonist. J. Pharm. Biomed. Anal., 13, 1541-1544.
-
(1995)
J. Pharm. Biomed. Anal.
, vol.13
, pp. 1541-1544
-
-
Coates, P.A.1
Blagbrough, I.S.2
Lewis, T.3
Potter, B.V.L.4
Rowan, M.G.5
-
8
-
-
0025605864
-
A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX
-
Couturier, S., Bertrand, D., Matter, J.-M., Hernandez, M.-C., Bertrand, S., Millar, N., Valera, S., Barkas, T. & Ballivet, M. (1990) A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX. Neuron, 5, 847-856.
-
(1990)
Neuron
, vol.5
, pp. 847-856
-
-
Couturier, S.1
Bertrand, D.2
Matter, J.-M.3
Hernandez, M.-C.4
Bertrand, S.5
Millar, N.6
Valera, S.7
Barkas, T.8
Ballivet, M.9
-
9
-
-
0032535583
-
Mammalian nicotinic receptors with α7 subunits that slowly desensitize and rapidly recover from α-bungarotoxin blockade
-
Cuevas, J. & Berg, D.K. (1998) Mammalian nicotinic receptors with α7 subunits that slowly desensitize and rapidly recover from α-bungarotoxin blockade. J. Neurosci., 18, 10335-10344.
-
(1998)
J. Neurosci.
, vol.18
, pp. 10335-10344
-
-
Cuevas, J.1
Berg, D.K.2
-
10
-
-
0032586785
-
3H]-methyllycaconitine: A new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors
-
3H]-methyllycaconitine: a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors. Neuropharmacology, 38, 679-690.
-
(1999)
Neuropharmacology
, vol.38
, pp. 679-690
-
-
Davies, A.R.L.1
Hardick, D.J.2
Blagbrough, I.S.3
Potter, B.V.L.4
Wolstenholme, A.J.5
Wonnacott, S.6
-
11
-
-
0027772476
-
Chimeric nicotinic serotonergic receptor combines distinct ligand-binding and channel specificities
-
Eisele, J.L., Bertrand, S., Galzi, J.L., Devillersthiery, A., Changeux, J.P. & Bertrand, D. (1993) Chimeric nicotinic serotonergic receptor combines distinct ligand-binding and channel specificities. Nature, 366, 479-483.
-
(1993)
Nature
, vol.366
, pp. 479-483
-
-
Eisele, J.L.1
Bertrand, S.2
Galzi, J.L.3
Devillersthiery, A.4
Changeux, J.P.5
Bertrand, D.6
-
12
-
-
0028171296
-
α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells
-
Elgoyhen, A.B., Johnson, D.S., Boulter, J., Vetter, D.E. & Heinemann, S. (1994) α9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell, 79, 705-715.
-
(1994)
Cell
, vol.79
, pp. 705-715
-
-
Elgoyhen, A.B.1
Johnson, D.S.2
Boulter, J.3
Vetter, D.E.4
Heinemann, S.5
-
13
-
-
0026593533
-
A subtype of nicotinic cholinergic receptor in rat brain is composed of α4-subunit and β2-subunit and is upregulated by chronic nicotine treatment
-
Flores, C.M., Gogers, S.W., Pabreza, L.A., Wolfe, B.B. & Kellar, K.J. (1992) A subtype of nicotinic cholinergic receptor in rat brain is composed of α4-subunit and β2-subunit and is upregulated by chronic nicotine treatment. Mol. Pharmacol., 41, 31-37.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 31-37
-
-
Flores, C.M.1
Gogers, S.W.2
Pabreza, L.A.3
Wolfe, B.B.4
Kellar, K.J.5
-
14
-
-
0021879860
-
Quantitative film autoradiography for tritium-methodological considerations
-
Geary, W.A., Toga, A.W. & Wooten, G.F. (1985) Quantitative film autoradiography for tritium-methodological considerations. Brain Res., 337, 99-108.
-
(1985)
Brain Res.
, vol.337
, pp. 99-108
-
-
Geary, W.A.1
Toga, A.W.2
Wooten, G.F.3
-
15
-
-
0032521360
-
Glutamate and GABA release are enhanced by different subtypes of presynaptic nicotinic receptors in the lateral geniculate nucleus
-
Guo, J.Z., Tredway, T.L. & Chiappinelli, V.A. (1998) Glutamate and GABA release are enhanced by different subtypes of presynaptic nicotinic receptors in the lateral geniculate nucleus J. Neurosci., 18, 1963-1969.
-
(1998)
J. Neurosci.
, vol.18
, pp. 1963-1969
-
-
Guo, J.Z.1
Tredway, T.L.2
Chiappinelli, V.A.3
-
16
-
-
0030474553
-
Nudicauline and elatine as potent norditerpenoid ligands at the rat neuronal α-bungarotoxin binding sites: Importance of the 2-(methylsuccinimido) benzoyl moiety for neuronal nicotinic acetylcholine receptor binding
-
Hardick, D.J., Blagbrough, I.S., Cooper, G., Potter, B.V.L., Critchley, T. & Wonnacott, S. (1996a) Nudicauline and elatine as potent norditerpenoid ligands at the rat neuronal α-bungarotoxin binding sites: Importance of the 2-(methylsuccinimido) benzoyl moiety for neuronal nicotinic acetylcholine receptor binding. J. Med. Chem., 39, 4860-4866.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 4860-4866
-
-
Hardick, D.J.1
Blagbrough, I.S.2
Cooper, G.3
Potter, B.V.L.4
Critchley, T.5
Wonnacott, S.6
-
17
-
-
0030018218
-
Isotopic enrichment by asymmetric deuteration. An investigation of the synthesis of deuterated (S)-(-)-methylsuccinic acids from itaconic acid
-
Hardick, D.J., Blagbrough, I.S. & Potter, B.V.L. (1996b) Isotopic enrichment by asymmetric deuteration. An investigation of the synthesis of deuterated (S)-(-)-methylsuccinic acids from itaconic acid. J. Am. Chem. Soc., 118, 5897-5903.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 5897-5903
-
-
Hardick, D.J.1
Blagbrough, I.S.2
Potter, B.V.L.3
-
18
-
-
0031450275
-
Neuronal nicotinic acetylcholine receptors as targets for drug discovery
-
Holladay, M.W., Dart, M.J. & Lynch, J.K. (1997) Neuronal nicotinic acetylcholine receptors as targets for drug discovery. J. Med. Chem., 40, 4169-4194.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 4169-4194
-
-
Holladay, M.W.1
Dart, M.J.2
Lynch, J.K.3
-
19
-
-
0023845177
-
Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems
-
MacAllan, D.R.E., Lunt, G.G., Wonnacott, S., Swanson, K.L., Rapoport, H. & Albuquerque, E.X. (1988) Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems. FEBS Lett., 226, 357-363.
-
(1988)
FEBS Lett.
, vol.226
, pp. 357-363
-
-
MacAllan, D.R.E.1
Lunt, G.G.2
Wonnacott, S.3
Swanson, K.L.4
Rapoport, H.5
Albuquerque, E.X.6
-
20
-
-
0023029997
-
Nicotinic binding sites in rat and mouse brain: Comparison of acetylcholine, nicotine and αBgt
-
Marks, M.J., Stitzel, J.A., Romm, E., Wehner, J.M. & Collins, A.C. (1986) Nicotinic binding sites in rat and mouse brain: Comparison of acetylcholine, nicotine and αBgt. Mol. Pharmacol., 30, 427-436.
-
(1986)
Mol. Pharmacol.
, vol.30
, pp. 427-436
-
-
Marks, M.J.1
Stitzel, J.A.2
Romm, E.3
Wehner, J.M.4
Collins, A.C.5
-
21
-
-
0026740393
-
Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment
-
Marks, M.J., Pauly, J.R., Gross, S.D., Demetris, E.S., Hermans-Borgmeyer, I., Heinemann, S. & Collins, A.C. (1992) Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment. J. Neurosci., 12, 2765-2784.
-
(1992)
J. Neurosci.
, vol.12
, pp. 2765-2784
-
-
Marks, M.J.1
Pauly, J.R.2
Gross, S.D.3
Demetris, E.S.4
Hermans-Borgmeyer, I.5
Heinemann, S.6
Collins, A.C.7
-
22
-
-
0022930827
-
The molecular neurobiology of the acetylcholine receptor
-
McCarthy, M.P., Earnest, J.P., Young, E.F., Choe, S. & Stroud, R.M. (1986) The molecular neurobiology of the acetylcholine receptor. Annu. Rev. Neurosci., 9, 383-413.
-
(1986)
Annu. Rev. Neurosci.
, vol.9
, pp. 383-413
-
-
McCarthy, M.P.1
Earnest, J.P.2
Young, E.F.3
Choe, S.4
Stroud, R.M.5
-
23
-
-
0018719111
-
The principle toxin of Delphinium brownii (Rydb.) and its mode of action
-
Nambi-Aiyar, V., Benn, M.H., Hanna, T., Jacyno, J., Roth, S.H. & Wilkins, J.L. (1979). The principle toxin of Delphinium brownii (Rydb.) and its mode of action. Experientia, 35, 1367-1368.
-
(1979)
Experientia
, vol.35
, pp. 1367-1368
-
-
Nambi-Aiyar, V.1
Benn, M.H.2
Hanna, T.3
Jacyno, J.4
Roth, S.H.5
Wilkins, J.L.6
-
24
-
-
0029670737
-
Neuronal α7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine
-
Palma, E., Bertrand, S., Binzoni, T. & Bertrand, D. (1996). Neuronal α7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine. J. Physiol. (Lond.), 491, 151-161.
-
(1996)
J. Physiol. (Lond.)
, vol.491
, pp. 151-161
-
-
Palma, E.1
Bertrand, S.2
Binzoni, T.3
Bertrand, D.4
-
25
-
-
0024327212
-
An autoradiographic analysis of cholinergic receptors in mouse brain
-
Pauly, J.R., Marks, M.J., Gross, S.D. & Collins, A.C. (1989) An autoradiographic analysis of cholinergic receptors in mouse brain. Brain Res. Bull., 22, 453-459.
-
(1989)
Brain Res. Bull.
, vol.22
, pp. 453-459
-
-
Pauly, J.R.1
Marks, M.J.2
Gross, S.D.3
Collins, A.C.4
-
26
-
-
0025943470
-
An autoradiographic analysis of cholinergic receptors in mouse brain after chronic nicotine treatment
-
Pauly, J.R., Marks, M.J., Gross, S.D. & Collins, A.C. (1991) An autoradiographic analysis of cholinergic receptors in mouse brain after chronic nicotine treatment. J. Pharm. Exp. Ther., 258, 1-10.
-
(1991)
J. Pharm. Exp. Ther.
, vol.258
, pp. 1-10
-
-
Pauly, J.R.1
Marks, M.J.2
Gross, S.D.3
Collins, A.C.4
-
27
-
-
0030728458
-
Neuronal α-bungarotoxin receptors differ structurally from other nicotinic acetylcholine receptors
-
Rangwala, F., Drisdel, R.C., Rakhilin, S., Ko, E., Atluri, P., Harkins, A.B., Fox. A.P., Salman, S.B. & Green, W.B. (1997) Neuronal α-bungarotoxin receptors differ structurally from other nicotinic acetylcholine receptors. J. Neurosci., 17, 8201-8212.
-
(1997)
J. Neurosci.
, vol.17
, pp. 8201-8212
-
-
Rangwala, F.1
Drisdel, R.C.2
Rakhilin, S.3
Ko, E.4
Atluri, P.5
Harkins, A.B.6
Fox, A.P.7
Salman, S.B.8
Green, W.B.9
-
28
-
-
0030175612
-
Nicotinic receptors in the development and modulation of CNS synapses
-
Role, L.W. & Berg, D.K. (1996) Nicotinic receptors in the development and modulation of CNS synapses. Neuron, 16, 1077-1085.
-
(1996)
Neuron
, vol.16
, pp. 1077-1085
-
-
Role, L.W.1
Berg, D.K.2
-
30
-
-
0025308827
-
Brain α-bungarotoxin-binding protein cDNAs and mABs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily
-
Schoepfer, R., Conroy, W.G., Whiting, P., Gore, M. & Lindstrom, J. (1990) Brain α-bungarotoxin-binding protein cDNAs and mABs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily. Neuron, 5, 35-48.
-
(1990)
Neuron
, vol.5
, pp. 35-48
-
-
Schoepfer, R.1
Conroy, W.G.2
Whiting, P.3
Gore, M.4
Lindstrom, J.5
-
31
-
-
0027518923
-
Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium
-
Seguela, P., Wadiche, J., Dineley-Miller, K., Dani, J.A. & Patrick, J.W. (1993) Molecular cloning, functional properties, and distribution of rat brain α7: a nicotinic cation channel highly permeable to calcium. J. Neurosci., 13, 596-604.
-
(1993)
J. Neurosci.
, vol.13
, pp. 596-604
-
-
Seguela, P.1
Wadiche, J.2
Dineley-Miller, K.3
Dani, J.A.4
Patrick, J.W.5
-
32
-
-
0000158143
-
Methyllycaconitine: A new probe that discriminates between nicotinic acetylcholine receptor subclasses
-
Wonnacott, S., Albuquerque, E.X. & Bertrand, D. (1993) Methyllycaconitine: a new probe that discriminates between nicotinic acetylcholine receptor subclasses. Meth. Neurosci., 12, 263-275.
-
(1993)
Meth. Neurosci.
, vol.12
, pp. 263-275
-
-
Wonnacott, S.1
Albuquerque, E.X.2
Bertrand, D.3
-
33
-
-
0032525992
-
Functional contribution of the α7 subunit to multiple subtypes of nicotinic receptors in embryonic sympathetic neurons
-
Yu, C. & Role, L.W. (1998a) Functional contribution of the α7 subunit to multiple subtypes of nicotinic receptors in embryonic sympathetic neurons. J. Physiol. (Lond.), 509, 651-655.
-
(1998)
J. Physiol. (Lond.)
, vol.509
, pp. 651-655
-
-
Yu, C.1
Role, L.W.2
-
34
-
-
0032526022
-
Functional contribution of the α5 subunit to neuronal nicotinic channels expressed by chick sympathetic ganglion neurons
-
Yu, C. & Role, L.W. (1998b) Functional contribution of the α5 subunit to neuronal nicotinic channels expressed by chick sympathetic ganglion neurons. J. Physiol. (Lond.), 509, 667-681.
-
(1998)
J. Physiol. (Lond.)
, vol.509
, pp. 667-681
-
-
Yu, C.1
Role, L.W.2
-
35
-
-
0029972573
-
Nicotinic acetylcholine receptors in separate brain regions exhibit different affinities for methyllycaconitine
-
Yum, L., Wolf, K.M. & Chiappinelli, V.A. (1996) Nicotinic acetylcholine receptors in separate brain regions exhibit different affinities for methyllycaconitine. Neuroscience, 72, 545-555.
-
(1996)
Neuroscience
, vol.72
, pp. 545-555
-
-
Yum, L.1
Wolf, K.M.2
Chiappinelli, V.A.3
-
36
-
-
0345131682
-
Identification of four classes of brain nicotinic receptors using β2 mutant mice
-
Zoli, M., Lena, C., Picciotto, M.R. & Changeux, J.P. (1998) Identification of four classes of brain nicotinic receptors using β2 mutant mice. J. Neurosci., 18, 4461-4472.
-
(1998)
J. Neurosci.
, vol.18
, pp. 4461-4472
-
-
Zoli, M.1
Lena, C.2
Picciotto, M.R.3
Changeux, J.P.4
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