The neurophysiology of brain injury

Clinical Neurophysiology

Volumn 115, Issue 1, 2004, Pages 4-18

  Gaetz, Michael ^a,b,c  

^a Aaken Laboratories   (United States)

^b SIMON FRASER UNIVERSITY   (Canada)

^c 11747 231st Street ^*  (Canada)

Author keywords

Acceleration; Brain hemorrhage; Deceleration; Diffuse axonal injury; Electrophysiology; Neurophysiology; Traumatic

Indexed keywords

ACCELERATION; AXONAL INJURY; BLOOD VESSEL INJURY; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN CORTEX; BRAIN EDEMA; BRAIN FUNCTION; BRAIN HEMATOMA; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN NECROSIS; BRAIN NERVE CELL; BRAIN STEM; CALCIUM TRANSPORT; CELL DAMAGE; CELL SWELLING; COGNITIVE DEFECT; COMA; COMMUNICATION DISORDER; COMPREHENSION; COMPUTER ASSISTED TOMOGRAPHY; CONTUSION; CYTOTOXICITY; DECELERATION; DISEASE COURSE; ELECTROENCEPHALOGRAM; ELECTRONEUROLOGY; ELECTROPHYSIOLOGY; EVENT RELATED POTENTIAL; EVOKED AUDITORY RESPONSE; EVOKED SOMATOSENSORY RESPONSE; FORCE; GLASGOW COMA SCALE; HUMAN; NEOCORTEX; NEUROFILAMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RETICULAR FORMATION; REVIEW; SHEAR STRESS; STROKE; UNCONSCIOUSNESS; WHITE MATTER;

EID: 0347990376     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-2457(03)00258-X     Document Type: Review

References (140)

1. Adams J.H., Mitchell D.E., Graham D.I., Doyle D. Diffuse brain damage of the immediate impact type: its relationship to "primary brain-stem damage" in head injury. Brain. 100:1977;489-502.
2. Adams J.H., Graham D.I., Gennarelli T.A., Maxwell W.L. Diffuse axonal injury in non-missile head injury. J Neurol Neurosurg Psychiatry. 54:1991;481-483.
3. Anderson D.C., Bundlie S., Rockswold G.L. Multimodal evoked potentials in closed head trauma. Arch Neurol. 41:1984;369-374.
4. Bain A.C., Raghupathi R., Meaney D.F. Dynamic stretch correlates to both morphological abnormalities and electrophysiological impairment in a model of traumatic axonal injury. J Neurotrauma. 18:2001;499-511.
5. Blumberg P.C., Scott G., Manavis J., Wainwright H., Simpson D.A., McLean A.J. Staining of amyloid precursor protein to study axonal damage in mild head injury. Lancet. 344:1994;1055-1056.
6. Bramlett H.M., Green E.J., Dietrich W.D. Exacerbation of cortical and hippocampal CA1 damage due to posttraumatic hypoxia following moderate fluid-percussion brain injury to rats. J Neurosurg. 91:1999;653-659.
7. Brust J.C.M. Cerebral circulation: stroke. Kandel E.R., Schwartz J.H., Jessell T.M. Principles of neural science. 3rd ed. 1991;1041-1049 Elsevier, New York, NY.
8. Bullock R., Maxwell W., Graham D., Teasdale G., Adams J. Glial swelling following human cerebral contusion: an ultrastructural study. J Neurol Neurosurg Psychiatry. 54:1991;427-434.
9. Byrne J.M., Connolly J.F., MacLean S.E., Gordon K.E., Beattie T.L. Brain activity and language assessment using event-related potentials: development of a clinical protocol. Dev Med Child Neurol. 41:1999;740-747.
10. Cant B.R., Hume A.L., Judson J.A., Shaw N.A. The assessment of severe head injury by short-latency somatosensory and brain-stem auditory evoked potentials. Electroenceph clin Neurophysiol. 65:1986;188-195.
11. Choi D. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1:1988;623-634.
12. Christman C., Grady S., Walker S., Holloway K., Povlishock J. Ultrastructural studies of diffuse axonal injury in humans. J Neurotrauma. 11:1994;173-186.
13. Connolly J.F. Applying cognitive research in the twenty-first century: event-related potentials in assessment. Brain Cogn. 2:2000;99-101.
14. Connolly J.F., Major A., Allen S., D'Arcy R.C. Performance on WISC-III and WAIS-R NI vocabulary subtests assessed with event-related brain potentials: an innovative method of assessment. J Clin Exp Neuropsychol. 21:1999;444-464.
15. Connolly J.F., Mate-Kole C.C., Joyce B.M. Global aphasia: an innovative assessment approach. Arch Phys Med Rehabil. 80:1999;1309-1315.
16. Cooper P.R. Gunshot wounds of the brain. Cooper P.R. Head injury. 3rd ed. 1993;355-371 Williams and Wilkins, Philadelphia, PA.
17. Cudmore L.J., Segalowitz S.J., Dywan J. EEG coherence shows altered frontal-parietal communication in mild TBI during a dual-task. Brain Cogn. 44:2000;86-90.
18. Dacey R.G., Vollmer D., Dikmen S.S. Mild head injury. Cooper P.R. Head injury. 3rd ed. 1993;159-182 Williams and Wilkins, Philadelphia, PA.
19. Denny-Brown D., Russell W. Experimental cerebral concussion. Brain. 64:1941;93-164.
20. Diagnostic and statistical manual of mental disorders. 4th ed. Text Revision (DSM-IV-TR). Washington, DC: American Psychiatric Association; 2000.
21. Duhaime A.C., Christian C.W., Rorke L.B., Zimmerman R.A. Nonaccidental head injury in infants - the "shaken baby syndrome" N Engl J Med. 338:1998;1822-1829.
22. Dunham C.M., Coates S., Cooper C. Compelling evidence for discretionary brain computed tomographic imaging in those patients with mild cognitive impairment after blunt trauma. J Trauma. 41:1996;679-686.
23. Dupuis F., Johnston K.M., Lavoie M., Lepore F., Lassonde M. Concussions in athletes produce brain dysfunction as revealed by event-related potentials. NeuroReport. 11:2000;4087-4092.
24. Ellis E., Dodson L., Police R. Restoration of cerebrovascular responsiveness to hyperventilation by the oxygen radical scavenger n-acetylcystine following experimental traumatic brain injury. J Neurosurg. 75:1991;774-779.
25. Ellwanger J., Rosenfeld J.P., Sweet J.J. P300 event-related brain potential as an index of recognition response to autobiographical and recently learned information in closed head injury patients. Clin Neuropsychol. 11:1997;428-432.
26. 42 in human CSF. Ann N Y Acad Sci. 903:2002;118-122.
27. Erb D.E., Povlishock J.T. Neuroplasticity following traumatic brain injury: a study of GABAergic terminal loss and recovery in the cat lateral vestibular nucleus. Exp Brain Res. 83:1991;253-267.
28. Facco E., Munari M. The role of evoked potentials in severe head injury. Intensive Care Med. 26:2000;998-1005.
29. Faden A., Demediuk P., Panter S., Vink R. The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science. 244:1989;798-800.
30. Fishman R. Brain edema. N Engl J Med. 293:1975;706-711.
31. Foltz E., Schmidt R. The role of the reticular formation in the coma of head injury. J Neurosurg. 13:1956;145-154.
32. Ford M.R., Khalil M. Evoked potential findings in mild traumatic brain injury 1: middle latency component augmentation and cognitive component attenuation. J Head Trauma Rehabil. 11:1996;1-15.
33. Gaetz M. An emerging role for event-related potentials in the assessment of brain injury. Clin Neurophysiol. 113:2002;1665-1666.
34. Gaetz M., Bernstein D. The current status of electrophysiologic procedures for the assessment of mild traumatic brain injury. J Head Trauma Rehabil. 16:2001;386-405.
35. Gaetz M., Weinberg H. Electrophysiological indices of persistent post-concussion symptoms. Brain Inj. 14:2000;815-832.
36. Gaetz M., Goodman D., Weinberg H. Electrophysiological evidence for the cumulative effects of concussion. Brain Inj. 14:2000;1077-1088.
37. Gennarelli T.A. Mechanisms of brain injury. J Emerg Med. 11:1993;5-11.
38. Gennarelli T.A. The spectrum of traumatic injury. Neuropathol Appl Neurobiol. 22:1996;509-513.
39. Gennarelli T.A., Graham D.I. Neuropathology of head injuries. Semin Clin Neuropsychiatry. 3:1998;160-175.
40. Gennarelli T.A., Thibault L.E., Adams J.H., Graham D.I., Thompson C.J., Marcincin R.P. Diffuse axonal injury and traumatic coma in the primate. Ann Neurol. 12:1982;564-574.
41. Gennarelli T.A., Thibault L.E., Tipperman R., Tomei G., Sergot R., Brown M., et al. Axonal injury in the optic nerve: a model simulating diffuse axonal injury in the brain. J Neurosurg. 71:1989;244-253.
42. Gentry L., Godersky J., Thompson B., Dunn V. Prospective comparative study of intermediate-field MR and CT in the evaluation of closed head trauma. Am J Radiol. 150:1988;673-682.
43. Gieron M.A., Korthals J.K., Riggs C.D. Diffuse axonal injury without direct head trauma and with delayed onset of coma. Pediatr Neurol. 19:1998;382-384.
44. Giza C.C., Hovda D.A. The neurometabolic cascade of concussion. J Athletic Training. 36:2001;228-235.
45. Grady M.S., McLaughlin M.R., Christman C.W., Valadka A.B., Flinger C.L., Povlishock J.T. The use of antibodies targeted against the neurofilament subunits for the detection of diffuse axonal injury in humans. J Neuropathol Exp Neurol. 52:1993;143-152.
46. Granovsky Y., Sprecher E., Hemli J., Yarnitsky D. P300 and stress in mild head injury patients. Electroenceph clin Neurophysiol. 108:1998;554-559.
47. Greenberg R.P., Mayer J.D., Becker D.P., Miller J.D. Evaluation of brain function in severe human head trauma with multimodality evoked potentials. Part 1: evoked brain injury potentials, methods and analysis. J Neurosurg. 47:1977;150-162.
48. Greenberg R.P., Becker D.P., Miller J.D., Mayer D.J. Evaluation of brain function in severe human head trauma with multimodality evoked potentials. Part 2: localization of brain dysfunction and correlation with posttraumatic neurological conditions. J Neurosurg. 47:1977;163-177.
49. Gupta N.K., Verma N.P., Guidice M.A., Kooi K.A. Visual evoked response in head trauma: pattern shift stimulus. Neurology. 36:1986;578-581.
50. Halgren E., Marinkovic K., Chauvel P. Generators of the late cognitive potentials in auditory and visual oddball tasks. Electroenceph clin Neurophysiol. 94:1995;156-164.
51. Hammoud D.A., Wasserman B.A. Diffuse axonal injuries: pathophysiology and imaging. Neuroimaging Clin N Am. 12:2002;205-216.
52. Hayes R., Dixon C. Neurochemical changes in mild head injury. Semin Neurol. 14:1994;25-31.
53. Hayes R.L., Pechura C.M., Katayama Y., Povlishock J.T., Giebel M.L., Becker D.P. Activation of pontine cholinergic sites implicated in unconsciousness following cerebral concussion in the cat. Science. 223:1984;301-303.
54. Henry G.K., Gross H.S., Herndon C.A., Furst C.J. Nonimpact brain injury: neurobehavioral correlates with consideration of physiological findings. Appl Neuropsychol. 7:2000;65-75.
55. Holbourn A.H.S. Mechanics of head injury. Lancet. 2:1943;438-441.
56. Ingebrigtsen T., Romner B. Routine early CT-scan is cost saving after minor head injury. Acta Neurol Scand. 93:1996;207-210.
57. Jane J., Steward O., Gennarelli T. Axonal degeneration induced by experimental noninvasive minor head injury. J Neurosurg. 62:1985;96-100.
58. Jenkins A., Teasdale G., Hadley M., MacPherson P., Rowan J. Brain lesions detected by magnetic resonance imaging in mild and severe head injuries. Lancet. 2:1986;445-446.
59. Kallakuri S., Cavanaugh J.M., Özaktay A.C., Takebayashi T. The effect of varying impact energy on diffuse axonal injury in the rat brain: a preliminary study. Exp Brain Res. 148:2003;419-424.
60. Kane N.M., Curry S.H., Rowlands C.A., Manara A.R., Lewis T., Moss T., et al. Event-related potentials - neurophysiological tools for predicting emergence and early outcome from traumatic coma. Intensive Care Med. 22:1996;39-46.
61. Kontos C., Wei E., Williams J., Kontos H., Povlishock J. Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo. Am J Physiol. 263:1992;H1234-H1242.
62. Lamarche M., Louvel J., Buser P., Rektor I. Intracerebral recordings of slow potentials in a contingent negative variation paradigm: an exploration in epileptic patients. Electroenceph clin Neurophysiol. 95:1995;268-276.
63. LeBlanc K.E. Concussion in sport: diagnosis, management, return to competition. Comp Ther. 25:1999;39-44.
64. Leclercq P.D., McKenzie J.E., Graham D.I., Gentleman S.M. Axonal injury is accentuated in the caudal corpus callosum of head-injured patients. J Neurotrauma. 18:2001;1-9.
65. Levin H.S. Neurobehavioral sequalae of closed head injury. Cooper P.R. Head injury. 3rd ed. 1993;525-551 Williams and Wilkins, Philadelphia, PA.
66. Levin H., Williams D., Eisenberg H., High W., Guinto F. Serial MRI and neurobehavioral findings after mild to moderate closed head injury. J Neurol Neurosurg Psychiatry. 55:1992;255-262.
67. Levin H.S., Mendelsohn D., Lilly M.A., Yeakley J., Song J., Scheibel R.S., et al. Magnetic resonance imaging in relation to functional outcome of pediatric closed head injury: a test of the Ommaya-Gennarelli model. Neurosurgery. 40:1997;432-441.
68. Lindenberg R., Fisher R., Durlacher S., Lovitt W., Freytag E. Lesions of the corpus callosum following blunt mechanical trauma to the head. Am J Pathol. 31:1955;297-318.
69. Livingston D.H., Loder P.A., Koziol J., Hunt C.D. The use of CT scanning to triage patients requiring admission following minimal head injury. J Trauma. 31:1991;483-489.
70. Livingston D.H., Lavery R.F., Passannante M.R., Skurnick J.H., Baker S., Fry D.E., et al. Emergency department discharge of patients with a negative cranial computed tomography scan after minimal head injury. Ann Surg. 1:2000;126-132.
71. Marchand Y., D'Arcy R.C.N., Connolly J.F. Linking neurophysiological and neuropsychological measures for aphasia assessment. Clin Neurophysiol. 113:2002;1715-1722.
72. Marmarou A., Adb-Elfattah Foda M.A., Brink W.V.D., Campbell J., Demetriadou K. A new model of diffuse brain injury in rats: Part I: pathophysiology and biomechanics. J Neurosurg. 80:1994;291-300.
73. Maxwell W., Kansayra A., Graham D., Adams J., Gennarelli T. Freeze-fracture studies of reactive myelinated nerve fibres after diffuse axonal injury. Acta Neuropathol. 76:1988;395-406.
74. Maxwell W.L., Watt C., Graham D.I., Gennarelli T.A. Ultrastructural evidence of axonal shearing as a result of lateral acceleration of the head in non-human primates. Acta Neuropathol. 86:1993;136-144.
75. Mazzini L., Pisano F., Zaccala M., Miscio G., Gareri F., Galante M. Somatosensory and motor evoked potentials at different stages of recovery from severe traumatic brain injury. Arch Phys Med Rehabil. 80:1999;33-39.
76. Mittl R., Grossman R., Hiehle J., Hurst R., Kauder D., Gennarelli T., et al. Prevalence of MR evidence of diffuse axonal injury in patients with mild head injury and normal head CT findings. Am J Neuroradiol. 15:1994;1583-1589.
77. Nelson C., Wei E., Povlishock J., Kontos H., Moskowitz M. Oxygen radicals in cerebral ischemia. Am J Physiol. 263:1992;H1356-H1362.
78. Niess C., Grauel U., Toennes S.W., Bratzke H. Incidence of axonal injury in human brain tissue. Acta Neuropathol. 104:2002;79-84.
79. Nilsson P., Ronne-Engstrom E., Flink R., Ungerstedt U., Carlson H., Hillered L. Epileptic seizure activity in the acute phase following cortical impact trauma. Brain Res. 637:1994;227-232.
80. Okonkwo D.O., Pettus E.H., Moroi J., Povlishock J.T. Alteration of the neurofilament sidearm and its relation to neurofilament compaction occurring with traumatic axonal injury. Brain Res. 784:1998;1-6.
81. Ommaya A., Gennarelli T. Cerebral concussion and traumatic unconsciousness: correlation of experimental and clinical observations on blunt head injuries. Brain. 97:1974;633-654.
82. Onaya M. Neuropathological investigation of cerebral white matter lesions caused by closed head injury. Neuropathology. 22:2002;243-251.
83. Oppenheimer D. Microscopic lesions of the brain following head injury. J Neurol Neurosurg Psychiatry. 31:1968;299-306.
84. Parsons L.C., Crosby L.J., Perlis M., Britt T., Jones P. Longitudinal sleep EEG power spectral analysis studies in adolescent with minor head injury. J Neurotrauma. 14:1997;549-559.
85. Peerless S., Rewcastle N. Shear injuries of the brain. CMAJ. 96:1967;577-582.
86. Pettus E., Christman C., Giebel M., Povlishock J. Traumatically induced altered membrane permeability: its relationship to traumatically induced reactive axonal change. J Neurotrauma. 5:1994;507-522.
87. Phillips L.L., Lyeth B.G., Hamm R.J., Povlishock J.T. Combined fluid percussion brain injury and entorhinal cortical lesion: a model for assessing the interaction between neuroexcitation and deafferentation. J Neurotrauma. 11:1994;641-656.
88. Picton T., Stuss D. Neurobiology of conscious experience. Curr Opin Neurobiol. 4:1994;256-265.
89. Pilz P. Axonal injury in head injury. Acta Neurochir Suppl (Wien). 32:1983;119-123.
90. Postmanur R.M., Newcomb J.K., Kampfl A., Hayes R.L. Light and confocal microscopic studies of evolutionary change in neurofilament proteins following cortical impact injury in the rat. Exp Neurol. 161:2000;15-26.
91. Povlishock J.T. Pathobiology of traumatically induced axonal injury in animals and man. Ann Emerg Med. 22:1993;980-986.
92. Povlishock J.T., Becker D.P. Fate of reactive axonal swellings induced by head injury. Lab Invest. 52:1985;540-552.
93. Povlishock J., Kontos H. The role of oxygen radicals in the pathobiology of traumatic brain injury. Hum Cell. 5:1992;345-353.
94. Povlishock J.T., Becker D.P., Cheng C.L.Y., Vaughan G.W. Axonal change in minor head injury. J Neuropathol Exp Neurol. 42:1983;225-242.
95. Povlishock J.T., Erb D.E., Astruc J. Axonal response to traumatic brain injury reactive axonal change, deafferentation, and neuroplasticity. J Neurotrauma Suppl. 9:1992;s189-s200.
96. Povlishock J., Hayes R., Michel M., McIntosh T. Workshop on animal models of traumatic brain injury. J Neurotrauma. 11:1994;723-731.
97. Povlishock J.T., Marmarou A., McIntosh T., Trojanowski J.Q., Moroi J. Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration. J Neuropathol Exp Neurol. 56:1997;347-359.
98. Raghupathi R., Margulies S.S. Traumatic axonal injury after closed head injury in the neonatal pig. J Neurotrauma. 19:2002;843-853.
99. Rosenberg C., Wogensen K., Starr A. Auditory brain-stem and middle- and long latency evoked potentials in coma. Arch Neurol. 41:1984;835-838.
100. Saatman K.E., Graham D.I., McIntosh T.K. The neuronal cytoskeleton is at risk after mild and moderate brain injury. J Neurotrama. 15:1998;1047-1058.
101. Sangal R.B., Sangal J.M. Closed head injury patients with mild cognitive complaints without neurological or psychiatric findings have abnormal visual P300 latencies. Biol Psychiatry. 39:1996;305-307.
102. Satz P., Alfano M.S., Light R., Morgenstern H., Zaucha K., Asarnow R.F., et al. Persistent post-concussive syndrome: a proposed methodology and literature review to determine the effects, if any, of mild head and other bodily injury. J Clin Exp Neuropsychol. 21:1999;620-628.
103. Schroder M., Muizelaar P., Bullock R., Salvant J., Povlishock J. Focal ischemia due to traumatic contusions documented by stable xenon-CT and ultrastructural studies. J Neurosurg. 82:1995;966-971.
104. Schwartz J.H. Synthesis and trafficking of neural proteins. Kandel E.R., Schwartz J.H., Jessell T.M. Principles of neural science. 3rd ed. 1991;49-65 Elsevier, New York, NY.
105. Shaw N. The neurophysiology of conscussion. Prog Neurobiol. 67:2002;281-344.
106. Shackford S.R., Wald S.L., Ross S.S., Cogbill T.H., Hoyt D.B., Morris J.A., et al. The clinical utility of computed tomographic scanning examination in the management of patients with minor head injuries. J Trauma. 33:1992;385-394.
107. Sieb R. A brain mechanism for attention. Med Hypotheses. 33:1990;145-153.
108. Slewa-Younan S., Green A.M., Baguley I.A., Felmingham K.L., Haig A., Gordan E. Is "gamma" (40 Hz) synchronous activity disturbed in patients with traumatic brain injury? Clin Neurophysiol. 113:2002;1640-1646.
109. Slobounov S., Sebastianelli W., Simon R. Neurophysiological and behavioural concomitants of mild brain injury in collegiate athletes. Clin Neurophysiol. 113:2002;185-193.
110. Smith D.H., Wolf J.A., Lusardi T.A., Lee V.M.-Y., Meaney D.F. High tolerance and delayed elastic response of cultured axons to dynamic stretch injury. J Neurosci. 19:1999;4263-4269.
111. Smith D.H., Chen X.-H., Nonaka M., Trojanowski J.Q., Lee V.M.-Y., Saatman K.E., et al. Accumulation of amyloid β and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig. J Neuropathol Exp Neurol. 58:1999;982-992.
112. Soldner F., Hölper B.M., Chone L., Wallenfang T. Evoked potentials in acute head injured patients with MRI-detected intracerebral lesions. Acta Neurochir (Wien). 143:2000;873-883.
113. Soustiel J.F., Hafner H., Guilburd J.N., Zaroor M., Levi L., Feinsod M. A physiological coma scale: grading of coma by combined use of brain-stem trigeminal and auditory evoked potentials and the Glasgow coma scale. Electroenceph clin Neurophysiol. 87:1993;277-283.
114. Stein S., Ross S. The value of computed tomographic scans in patients with low-risk head injuries. Neurosurgery. 26:1990;638-640.
115. Stewart-Amidei C. Assessing the comatose patient in the intensive care unit. AACN Clin Issues Crit Care Nurs. 2:1991;613-622.
116. Strich S. Diffuse degeneration of the cerebral white matter in severe dementia following head injury. J Neurol Neurosurg Psychiatry. 19:1956;163-185.
117. Strich S. Shearing of nerve fibres as a cause of brain damage due to head injury. Lancet. 2:1961;443-448.
118. Stone J.R., Walker S.A., Povlishock J.T. The visualization of a new class of traumatically injured axons through the use of a modified method of microwave antigen retrieval. Acta Neuropathol. 97:1999;335-345.
119. Stone J.R., Singleton R.H., Povlishock J.T. Intra-axonal neurofilament compaction does not evoke axonal swelling in all traumatically injured axons. Exp Neurol. 172:2001;320-331.
120. Stone J.R., Okonkwo D.O., Singleton R.H., Mutlu L.K., Helm G.A., Povlishock J.T. Caspase-3-mediated cleavage of amyloid precursor protein and formation of amyloid β peptide in traumatic brain injury. J Neurotrauma. 19:2002;601-614.
121. Sutton R., Lescaudron L., Stein D. Unilateral cortical contusion injury in the rat: vascular disruption and temporal development of cortical necrosis. J Neurotrauma. 10:1993;135-149.
122. Tebano M.T., Cameroni M., Gallozzi G., Loizzo A., Palazzino G., Pezzini G., et al. EEG spectral analysis after minor head injury in man. Electroenceph clin Neurophysiol. 70:1988;185-189.
123. Thatcher R.W., Walker R.A., Gerson I., Geisler F.H. EEG discriminant analyses of mild head trauma. Electroenceph clin Neurophysiol. 73:1989;93-106.
124. Thatcher R.W., Biver C., McAlaster R., Camacho M., Salazar A. Biophysical linkage between MRI and EEG amplitude in closed head injury. Neuroimage. 7:1998;352-367.
125. Thatcher R.W., Biver C., McAlaster R., Salazar A. Biophysical linkage between MRI and EEG coherence in closed head injury. Neuroimage. 8:1998;307-326.
126. Thatcher R.W., Biver C., Gomez J.F., North D., Curtin R., Walker R.A., et al. Estimation of the EEG power spectrum using MRI T2 relaxation time in traumatic brain injury. Clin Neurophysiol. 112:2001;1729-1745.
127. Thatcher R.W., North D.M., Curtin R.T., Walker R.A., Biver C.J., Gomez J.F., et al. An EEG severity index of traumatic brain injury. J Neuropsychiatry Clin Neurosci. 13:2001;77-87.
128. Thornton K.E. Exploratory analysis: mild head injury, discriminant analysis with high frequency bands (32-64 Hz) under attentional activation conditions and does time heal? J Neurother. Fall/Winter:1999;1-10.
129. Turner B., Knapp M. Consciousness: a neurobiological approach. Integr Physiol Behav Sci. 30:1995;151-156.
130. van Zomeren A.H., Brower W.H. Clinical neuropsychology of attention. 1994;Oxford University Press, New York, NY.
131. Varney N.R., Varney R.N. Brain injury without head injury. Some physics of automobile collisions with particular reference to brain injuries occurring without physical head trauma. Appl Neuropsychol. 2:1995;47-62.
132. Vespa P.M., Boscardin W.J., Hovda D.A., McArthur D.L., Nuwer M.C., Martin N.A., et al. Early and persistent impaired percent alpha variability on continuous electroencephalography monitoring as predictive of poor outcome after traumatic brain injury. J Neurosurg. 97:2002;84-92.
133. Wahl M., Schilling L. Regulation of blood flow - a brief review. Acta Neurochir (Suppl). 59:1993;3-10.
134. Ward A.A. The physiological basis of concussion. J Neurosurg. 15:1958;129-134.
135. Ward A.A. The physiology of concussion. Caveness W.F., Walker A.E. Proceedings of the Conference on Head Injury. 1966;203-208 Lippincott, Philadelphia, PA.
136. Watson M.R., Fenton G.W., McClelland R.J., Lumsden J., Headley M., Rutherford W.H. The post-concussional state: neurophysiological aspects. Br J Psychiatry. 167:1995;514-521.
137. Wilson J.T.S., Wiedmann K.D., Hadley D.M., Condon B., Teasdale G., Brooks D.N. Early and late magnetic resonance imaging and neuropsychological outcome after head injury. J Neurol Neurosurg Psychiatry. 51:1988;391-396.
138. Wolf J.A., Stys P.K., Lusardi T., Meaney D.H., Smith D.H. Traumatic axonal injury induces calcium influx modulated by tetrodotoxin sodium channels. J Neurosci. 21:2001;1923-1930.
139. Yaghmai A., Povlishock J. Traumatically induced reactive change as visualized through the use of monoclonal antibodies targeted to the neurofilament subunits. J Neuropathol Exp Neurol. 51:1992;158-176.
140. Young R.J., Destian S. Imaging of traumatic intracranial hemorrhage. Neuroimaging Clin N Am. 12:2002;189-204.