Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: Accumulation in Purkinje cells of the cerebellum

Journal of Molecular Neuroscience

Volumn 27, Issue 3, 2005, Pages 303-310

  Candelario Jalil, Eduardo ^a   Slawik, Helen ^a   Ridelis, Ingrid ^a   Waschbisch, Anne ^a   Akundi, Ravi Shankar ^a   Hüll, Michael ^a   Fiebich, Bernd L ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cerebellum; Cyclooxygenase; EP1; Neuroimmunology; Prostaglandin E2; Prostanoid receptors; Purkinje cells; Rat brain

Indexed keywords

PROSTAGLANDIN E RECEPTOR;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN STEM; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DENDRITE; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PARIETAL LOBE; PERIKARYON; PREFRONTAL CORTEX; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PURKINJE CELL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; WESTERN BLOTTING;

ANIMALS; BRAIN; FEMALE; MALE; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROSTAGLANDIN E; RNA, MESSENGER;

ANIMALIA;

EID: 27644451820     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/JMN:27:3:303     Document Type: Article

References (53)

1. Adams J., Collaço-Moraes Y., and De Belleroche J. (1996) Cyclooxygenase-2 induction in cerebral cortex: An intracellular response to synaptic excitation. J. Neurochem. 66, 6-13.
2. Airaksinen M. S., Eilers J., Garaschuk O., Thoenen H., Konnerth A., and Meyer M. (1997) Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc. Natl. Acad. Sci. U. S. A. 94, 1488-1493.
3. Akundi R. S., Candelario-Jalil E., Hess S., Hüll M., Lieb K., Gebicke-Haerter P. J., and Fiebich B. L. (2005). Signal transduction pathways regulating cyclooxygenase-2 in lipopolysaccharide-activated primary rat microglia. Glia 51, 199-208. http://www3.interscience.wiley.com/cgi-bin/ abstract/110434693/ABSTRACT
4. Barski J. J., Hartmann J., Rose C. R., Hoebeek F., Morl K., Noll-Hussong M., et al. (2003) Calbindin in cerebellar Purkinje cells is a critical determinant of the precision of motor coordination. J. Neurosci. 23, 3469-3477.
5. Bastien L., Sawyer N., Grygorczyk R., Metters K. M., and Adam M. (1994) Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype. J. Biol. Chem. 269, 11,873-11,877.
6. Batshake B., Nilsson C., and Sundelin J. (1995) Molecular characterization of the mouse prostanoid EP1 receptor gene. Eur. J. Biochem. 231, 809-814.
7. Bauer M. K. A., Lieb K., Schulze-Osthoff K., Berger M., Gebicke-Haerter P. J., Bauer J., and Fiebich B. L. (1997) Expression and regulation of cyclooxygenase-2 in rat microglia. Eur. J. Biochem. 243, 726-731.
8. Boie Y., Stocco R., Sawyer N., Slipetz D. M., Ungrin M. D., Neuschafer-Rube F., et al. (1997) Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. Eur. J. Pharmacol. 340, 227-241.
9. Breder C. D., Dewitt D., and Kraig R. P. (1995) Characterization of inducible cyclooxygenase in rat brain. J. Comp. Neurol. 355, 296-315.
10. Candelario-Jalil E., Al Dalain S. M., Castillo R., Martinez G., and Fernandez O. S. (2001a) Selective vulnerability to kainate-induced oxidative damage in different rat brain regions. J. Appl. Toxicol. 21, 403-407.
11. Candelario-Jalil E., González-Falcón A., García-Cabrera M., León O.S., and Fiebich B. L. (2004) Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat. Brain Res. 1007, 98-108.
12. Candelario-Jalil E., Mhadu N. H., Al Dalain S. M., Martinez G., and Leon O. S. (2001b) Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils. Neurosci. Res. 41, 233-241.
13. Carlson N. G. (2003) Neuroprotection of cultured cortical neurons mediated by the cyclooxygenase-2 inhibitor APHS can be reversed by a prostanoid. J Neurosci Res 71, 79-88.
14. Chen C., Magee J. C., and Bazan N. G. (2002) Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity. J. Neurophysiol. 87, 2851-2857.
15. Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal. Biochem. 162, 156,157.
16. Collaco-Moraes Y., Aspey B., Harrison M., and De Belleroche J. (1996) Cyclo-oxygenase-2 messenger RNA induction in focal cerebral ischemia. J. Cereb. Blood Flow Metab. 16, 1366-1372.
17. Ek M., Arias C., Sawchenko P., and Ericsson-Dahlstrand A. (2000) Distribution of the EPS prostaglandin E(2) receptor subtype in the rat brain: relationship to sites of interleukin-1-induced cellular responsiveness. J. Comp. Neurol. 428, 5-20.
18. Fiebich B. L., Biber K., Lieb K., van Calker D., Berger M., Bauer J., and Gebicke-Haerter P. J. (1996) Cyclooxygenase-2 expression in rat microglia is induced by adenosine A2a-receptors. Glia 18, 152-160.
19. Funk C. D., Furci L., Fitzgerald G. A., Grygorczyk R., Rochette C., Bayne M. A., et al. (1993) Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype. J. Biol. Chem. 268, 26,767-26,772.
20. Glowinski J. and Iversen L. L. (1966) Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J. Neurochem. 13, 655-669.
21. Gold M. S., Levine J. D., and Correa A. M. (1998) Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro. J. Neurosci. 18, 10,345-10,355.
22. Katoh H., Watabe A., Sugimoto Y., Ichikawa A., and Negishi M. (1995) Characterization of the signal transduction of prostaglandin E receptor EP1 subtype in cDNA-transfected Chinese hamster ovary cells. Biochim. Biophys. Acta 1244, 41-48.
23. Kaufmann W. E., Worley P. F., Pegg J., Bremer M., and Isakson P. (1996) COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at post- synaptic sites in rat cerebral cortex. Proc. Natl. Acad. Sci. U. S. A. 93, 2317-2321.
24. Kawano T., Anrather J., Frys K., Zhou P., and Iadecola C. (2004). Activation of prostaglandin EP1 receptors contributes to COX-2-dependent neurotoxicity. Soc. Neurosci. Abs. 30, 600.8.
25. Konnerth A., Dreessen J., and Augustine G. J. (1992) Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. Proc. Natl. Acad. Sci. U. S. A. 89, 7051-7055.
26. Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head bacteriophage T4. Nature 227, 680-685.
27. 2. Proc. Natl. Acad. Sci. U. S. A. 94, 6500-6505.
28. Minami T., Nakano H., Kobayashi T., Sugimoto Y., Ushikubi F., Ichikawa A., et al. (2001) Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice. Br. J. Pharmacol. 133, 438-444.
29. Minghetti L., Polazzi E., Nicolini A., Creminon C., and Levi G. (1996) Interferon-gamma and nitric oxide down-regulate lipopolysaccharide-induced prostanoid production in cultured rat microglial cells by inhibiting cyclooxygenase-2 expression. J. Neurochem. 66, 1963-1970.
30. Nakamura K., Kaneko T., Yamashita Y., Hasegawa H., Katoh H., and Negishi M. (2000) Immunohistochemical localization of prostaglandin EP3 receptor in the rat nervous system. J. Comp. Neurol. 421, 543-569.
31. Narumiya S., Sugimoto Y., and Ushikubi F. (1999) Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 79, 1193-1226.
32. Negishi M., Ito S., and Hayaishi O. (1990) Involvement of protein kinase C in prostaglandin E2-induced catecholamine release from cultured bovine adrenal chromaffin cells. J. Biol. Chem. 265, 6182-6188.
33. Negishi M., Sugimoto Y., and Ichikawa A. (1995) Molecular mechanisms of diverse actions of prostanoid receptors. Biochim. Biophys. Acta 1259, 109-119.
34. Nicol G. D., Vasko M. R., and Evans A. R. (1997) Prostaglandins suppress an outward potassium current in embryonic rat sensory neurons. J. Neurophysiol. 77, 167-176.
35. Nogawa S., Zhang F., Ross M. E., and Iadecola C. (1997) Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage. J. Neurosci. 17, 2746-2755.
36. O'Banion M. K. (1999) COX-2 and Alzheimer's disease: potential roles in inflammation and neurodegeneration. Exp. Opin. Invest. Drugs 8, 1521-1536.
37. Oka T. and Hori T. (1994) EP1-receptor mediation of prostaglandin E2-induced hyperthermia in rats. Am. J. Physiol. 267, R289-R294.
38. Pardue S., Rapoport S. I., and Bosetti F. (2003). Colocalization of cytosolic phospholipase A2 and cyclooxygenase-2 in Rhesus monkey cerebellum. Mol. Brain Res. 116, 106-114.
39. Regan J. W., Bailey T. J., Pepperl D. J., Pierce K. L., Bogardus A. M., Donello J. E., et al. (1994) Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype. Mol. Pharmacol. 46, 213-220.
40. Saab C. Y. and Willis W. D. (2003) The cerebellum: organization, functions and its role in nociception. Brain Res. Brain Res. Rev. 42, 85-95.
41. Sakurai M. (1990) Calcium is an intracellular mediator of the climbing fiber in induction of cerebellar long-term depression. Proc. Natl. Acad. Sci. U. S. A. 87, 3383-3385.
42. Sanz O., Estrada A., Ferrer I., and Planas A. M. (1997) Differential cellular distribution and dynamics of HSP70, cyclooxygenase-2, and c-Fos in the rat brain after transient focal ischemia or karnic acid. Neuroscience 80, 221-232.
43. Seibert K., Zhang Y., Leahy K., Hauser S., Masferrer J., and Isakson P. (1997) Distribution of COX-1 and COX-2 in normal and inflamed tissues. Adv. Exp. Med. Biol. 400A, 167-170.
44. Shaw K. N., Commins S., and O'Mara S. M. (2003) Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor. Eur. J. Neurosci. 17, 2438-2446.
45. Shibuya I., Tanaka K., Uezono Y., Ueta Y., Toyohira Y., Yanagihara N., et al. (1999) Prostaglandin E2 induces Ca2+ release from ryanodine/caffeine- sensitive stores in bovine adrenal medullary cells via EP1-like receptors. J. Neurochem. 73, 2167-2174.
46. Slawik H., Volk B., Fiebich B., and Hull M. (2004) Microglial expression of prostaglandin EPS receptor in excitotoxic lesions in the rat striatum. Neurochem. Int. 45, 653-660.
47. Smith W. L., DeWitt D. L., and Garavito R. M. (2000) Cyclooxygenases: structural, cellular, and molecular biology. Annu. Rev. Biochem. 69, 145-182.
48. Stock J. L., Shinjo K., Burkhardt J., Roach M., Taniguchi K., Ishikawa T., et al. (2001) The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure. J. Clin. Invest. 107, 325-331.
49. Sugimoto Y., Narumiya S., and Ichikawa A. (2000) Distribution and function of prostanoid receptors: studies from knockout mice. Prog. Lipid Res. 39, 289-314.
50. Watabe A., Sugimoto Y., Honda A., Irie A., Namba T., Negishi M., et al. (1993) Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor. J. Biol. Chem. 268, 20,175-20,178.
51. Yamagata K., Andreasson K. I., Kaufmann W. E., Barnes C. A., and Worley P. F. (1993) Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 11, 371-386.
52. Zhang J. and Rivest S. (1999) Distribution, regulation and colocalization of the genes encoding the EP2- and EP4-PGE2 receptors in the rat brain and neuronal responses to systemic inflammation. Eur. J. Neurosci. 11, 2651-2668.
53. 2 receptor EP1 mediates COX-2-dependent cell death in hippocampal slices. Soc. Neurosci. Abs. 30, 600.9.