Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition

Neurobiology of Disease

Volumn 22, Issue 1, 2006, Pages 165-176

  DeRidder, Michael N ^a   Simon, Melissa J ^a   Siman, Robert ^b   Auberson, Yves P ^c   Raghupathi, Ramesh ^d   Meaney, David F ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

^d DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Calpain; Caspase 3; Hippocampus; N methyl D aspartate receptor; Organotypic; Traumatic brain injury

Indexed keywords

CALPAIN; CASPASE 3; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; DENTATE GYRUS; ENZYME ACTIVATION; HIPPOCAMPUS; IMMUNOREACTIVITY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BIOLOGICAL MARKERS; BRAIN INJURIES; CALPAIN; CASPASE 3; CASPASES; DENTATE GYRUS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; HIPPOCAMPUS; MECHANOTRANSDUCTION, CELLULAR; NECROSIS; NEURONS; ORGAN CULTURE TECHNIQUES; PROTEIN SUBUNITS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; SPECTRIN; SYNAPTIC TRANSMISSION; UP-REGULATION;

EID: 33645061251     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.10.011     Document Type: Article

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