-
1
-
-
0009530192
-
Human ICE/CED-3 protease nomenclature
-
letter
-
Alnemri ES, Livingston DJ, Nicholson DW, Salvesen G, Thornberry NA, Wong WW, Yuan J: Human ICE/CED-3 protease nomenclature. Cell 87:171, 1996 (letter).
-
(1996)
Cell
, vol.87
, pp. 171
-
-
Alnemri, E.S.1
Livingston, D.J.2
Nicholson, D.W.3
Salvesen, G.4
Thornberry, N.A.5
Wong, W.W.6
Yuan, J.7
-
2
-
-
0030450402
-
A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases
-
Amin AR, Attur MG, Thakker GD, Patel PD, Vyas PR, Patel RN, Patel IR, Abramson SB: A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases. Proc Natl Acad Sci U S A 93:14014-14019, 1996.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14014-14019
-
-
Amin, A.R.1
Attur, M.G.2
Thakker, G.D.3
Patel, P.D.4
Vyas, P.R.5
Patel, R.N.6
Patel, I.R.7
Abramson, S.B.8
-
3
-
-
0028179849
-
Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells
-
Ankarcrona M, Dypbukt JM, Brune B, Nicotera P: Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells. Exp Cell Res 213:172-177, 1994.
-
(1994)
Exp Cell Res
, vol.213
, pp. 172-177
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Brune, B.3
Nicotera, P.4
-
4
-
-
0032839242
-
Current status of neuroprotection trials for traumatic brain injury: Lessons from animal models and clinical studies
-
Bullock MR, Lyeth BG, Muizelaar JP: Current status of neuroprotection trials for traumatic brain injury: Lessons from animal models and clinical studies. Neurosurgery 45:207-217, 1999.
-
(1999)
Neurosurgery
, vol.45
, pp. 207-217
-
-
Bullock, M.R.1
Lyeth, B.G.2
Muizelaar, J.P.3
-
5
-
-
0026517239
-
Molecular cloning of the interleukin-1β converting enzyme
-
Cerretti DP, Kozlosky CJ, Mosley B, Nelson N, Van Ness K, Greenstreet TA, March CJ, Kronheim SR, Druck T, Cannizzaro LA, Huebner K, Black RA: Molecular cloning of the interleukin-1β converting enzyme. Science 256:97-100, 1992.
-
(1992)
Science
, vol.256
, pp. 97-100
-
-
Cerretti, D.P.1
Kozlosky, C.J.2
Mosley, B.3
Nelson, N.4
Van Ness, K.5
Greenstreet, T.A.6
March, C.J.7
Kronheim, S.R.8
Druck, T.9
Cannizzaro, L.A.10
Huebner, K.11
Black, R.A.12
-
6
-
-
0028661078
-
SOD-1 transgenic mice as a model for studies of neuroprotection in stroke and brain trauma
-
Chan PH, Epstein CJ, Kinouchi H, Kamii H, Imaizumi S, Yang G, Chen SF, Gafni J, Carlson E: SOD-1 transgenic mice as a model for studies of neuroprotection in stroke and brain trauma. Ann N Y Acad Sci 738:93-103, 1994.
-
(1994)
Ann N Y Acad Sci
, vol.738
, pp. 93-103
-
-
Chan, P.H.1
Epstein, C.J.2
Kinouchi, H.3
Kamii, H.4
Imaizumi, S.5
Yang, G.6
Chen, S.F.7
Gafni, J.8
Carlson, E.9
-
7
-
-
0033912716
-
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease
-
Chen M, Ona VO, Li M, Ferrante RJ, Fink KB, Zhu S, Bian J, Guo L, Farrell LA, Hersch SM, Hobbs W, Vonsattel JP, Cha JH, Friedlander RM: Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nat Med 6:797-801, 2000.
-
(2000)
Nat Med
, vol.6
, pp. 797-801
-
-
Chen, M.1
Ona, V.O.2
Li, M.3
Ferrante, R.J.4
Fink, K.B.5
Zhu, S.6
Bian, J.7
Guo, L.8
Farrell, L.A.9
Hersch, S.M.10
Hobbs, W.11
Vonsattel, J.P.12
Cha, J.H.13
Friedlander, R.M.14
-
8
-
-
0033954672
-
Caspase-3 mediated neuronal death after traumatic brain injury in rats
-
Clark RS, Kochanek PM, Watkins SC, Chen M, Dixon CE, Seidberg NA, Melick J, Loeffert JE, Nathaniel PD, Jin KL, Graham SH: Caspase-3 mediated neuronal death after traumatic brain injury in rats. J Neurochem 74:740-753, 2000.
-
(2000)
J Neurochem
, vol.74
, pp. 740-753
-
-
Clark, R.S.1
Kochanek, P.M.2
Watkins, S.C.3
Chen, M.4
Dixon, C.E.5
Seidberg, N.A.6
Melick, J.7
Loeffert, J.E.8
Nathaniel, P.D.9
Jin, K.L.10
Graham, S.H.11
-
9
-
-
0032146787
-
Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period
-
Conti AC, Raghupathi R, Trojanowski JQ, McIntosh TK: Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. J Neurosci 18:5663-5672, 1998.
-
(1998)
J Neurosci
, vol.18
, pp. 5663-5672
-
-
Conti, A.C.1
Raghupathi, R.2
Trojanowski, J.Q.3
McIntosh, T.K.4
-
10
-
-
0029978182
-
Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
-
Enari M, Talanian RV, Wong WW, Nagata S: Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380:723-726, 1996.
-
(1996)
Nature
, vol.380
, pp. 723-726
-
-
Enari, M.1
Talanian, R.V.2
Wong, W.W.3
Nagata, S.4
-
11
-
-
0031892704
-
Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family
-
Endres M, Namura S, Shimizu-Sasamata M, Waeber C, Zhang L, Gomez-Isla T, Hyman BT, Moskowitz MA: Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family. J Cereb Blood Flow Metab 18:238-247, 1998.
-
(1998)
J Cereb Blood Flow Metab
, vol.18
, pp. 238-247
-
-
Endres, M.1
Namura, S.2
Shimizu-Sasamata, M.3
Waeber, C.4
Zhang, L.5
Gomez-Isla, T.6
Hyman, B.T.7
Moskowitz, M.A.8
-
12
-
-
0032708427
-
Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade
-
Fink KB, Andrews LJ, Butler WE, Ona VO, Li M, Bogdanov M, Endres M, Khan SQ, Namura S, Stieg PE, Beal MF, Moskowitz MA, Yuan J, Friedlander RM: Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade. Neuroscience 94:1213-1218, 1999.
-
(1999)
Neuroscience
, vol.94
, pp. 1213-1218
-
-
Fink, K.B.1
Andrews, L.J.2
Butler, W.E.3
Ona, V.O.4
Li, M.5
Bogdanov, M.6
Endres, M.7
Khan, S.Q.8
Namura, S.9
Stieg, P.E.10
Beal, M.F.11
Moskowitz, M.A.12
Yuan, J.13
Friedlander, R.M.14
-
13
-
-
0031730617
-
ICE, neuronal apoptosis and neurodegeneration
-
Friedlander RM, Yuan J: ICE, neuronal apoptosis and neurodegeneration. Cell Death Differ 5:823-831, 1998.
-
(1998)
Cell Death Differ
, vol.5
, pp. 823-831
-
-
Friedlander, R.M.1
Yuan, J.2
-
14
-
-
1842407161
-
Inhibition of ICE slows ALS in mice
-
letter
-
Friedlander RM, Brown RH, Gagliardini V, Wang J, Yuan J: Inhibition of ICE slows ALS in mice. Nature 388:31, 1997 (letter).
-
(1997)
Nature
, vol.388
, pp. 31
-
-
Friedlander, R.M.1
Brown, R.H.2
Gagliardini, V.3
Wang, J.4
Yuan, J.5
-
15
-
-
8044252166
-
Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury
-
Friedlander RM, Gagliardini V, Hara H, Fink KB, Li W, MacDonald G, Fishman MC, Greenberg AH, Moskowitz MA, Yuan J: Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med 185:933-940, 1997.
-
(1997)
J Exp Med
, vol.185
, pp. 933-940
-
-
Friedlander, R.M.1
Gagliardini, V.2
Hara, H.3
Fink, K.B.4
Li, W.5
MacDonald, G.6
Fishman, M.C.7
Greenberg, A.H.8
Moskowitz, M.A.9
Yuan, J.10
-
16
-
-
0029788702
-
Functional role of interleukin 1β (IL-1β) in IL-1β-converting enzyme-mediated apoptosis
-
Friedlander RM, Gagliardini V, Rotello RJ, Yuan J: Functional role of interleukin 1β (IL-1β) in IL-1β-converting enzyme-mediated apoptosis. J Exp Med 184:717-724, 1996.
-
(1996)
J Exp Med
, vol.184
, pp. 717-724
-
-
Friedlander, R.M.1
Gagliardini, V.2
Rotello, R.J.3
Yuan, J.4
-
17
-
-
0034626090
-
Traumatic brain injury
-
Ghajar J: Traumatic brain injury. Lancet 356:923-929, 2000.
-
(2000)
Lancet
, vol.356
, pp. 923-929
-
-
Ghajar, J.1
-
18
-
-
0030972543
-
Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein
-
Hara H, Fink K, Endres M, Friedlander RM, Gagliardini V, Yuan J, Moskowitz MA: Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein. J Cereb Blood Flow Metab 17:370-375, 1997.
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, pp. 370-375
-
-
Hara, H.1
Fink, K.2
Endres, M.3
Friedlander, R.M.4
Gagliardini, V.5
Yuan, J.6
Moskowitz, M.A.7
-
19
-
-
0030614952
-
Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
-
Hara H, Friedlander RM, Gagliardini V, Ayata C, Fink K, Huang Z, Shimizu-Sasamata M, Yuan J, Moskowitz MA: Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proc Natl Acad Sci U S A 94:2007-2012, 1997.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 2007-2012
-
-
Hara, H.1
Friedlander, R.M.2
Gagliardini, V.3
Ayata, C.4
Fink, K.5
Huang, Z.6
Shimizu-Sasamata, M.7
Yuan, J.8
Moskowitz, M.A.9
-
20
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO: The biochemistry of apoptosis. Nature 407:770-776, 2000.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
21
-
-
0026048272
-
Interleukin 1 is processed and released during apoptosis
-
Hogquist KA, Nett MA, Unanue ER, Chaplin DD: Interleukin 1 is processed and released during apoptosis. Proc Natl Acad Sci U S A 88:8485-8489, 1991.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 8485-8489
-
-
Hogquist, K.A.1
Nett, M.A.2
Unanue, E.R.3
Chaplin, D.D.4
-
22
-
-
0033970987
-
Intracerebral administration of interleukin-1β and induction of inflammation, apoptosis, and vasogenic edema
-
Holmin S, Mathiesen T: Intracerebral administration of interleukin-1β and induction of inflammation, apoptosis, and vasogenic edema. J Neurosurg 92:108-120, 2000.
-
(2000)
J Neurosurg
, vol.92
, pp. 108-120
-
-
Holmin, S.1
Mathiesen, T.2
-
23
-
-
0034192466
-
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions
-
Kang SJ, Wang S, Hara H, Peterson EP, Namura S, Amin-Hanjani S, Huang Z, Srinivasan A, Tomaselli KJ, Thornberry NA, Moskowitz MA, Yuan J: Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J Cell Biol 149:613-622, 2000.
-
(2000)
J Cell Biol
, vol.149
, pp. 613-622
-
-
Kang, S.J.1
Wang, S.2
Hara, H.3
Peterson, E.P.4
Namura, S.5
Amin-Hanjani, S.6
Huang, Z.7
Srinivasan, A.8
Tomaselli, K.J.9
Thornberry, N.A.10
Moskowitz, M.A.11
Yuan, J.12
-
24
-
-
0033601995
-
Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity
-
Klevenyi P, Andreassen O, Ferrante RJ, Schleicher JR Jr, Friedlander RM, Beal MF: Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity. Neuroreport 10:635-638, 1999.
-
(1999)
Neuroreport
, vol.10
, pp. 635-638
-
-
Klevenyi, P.1
Andreassen, O.2
Ferrante, R.J.3
Schleicher J., Jr.4
Friedlander, R.M.5
Beal, M.F.6
-
25
-
-
0034638259
-
Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury
-
Li M, Ona VO, Chen M, Kaul M, Tenneti L, Zhang X, Stieg PE, Lipton SA, Friedlander RM: Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury. Neuroscience 99:333-342, 2000.
-
(2000)
Neuroscience
, vol.99
, pp. 333-342
-
-
Li, M.1
Ona, V.O.2
Chen, M.3
Kaul, M.4
Tenneti, L.5
Zhang, X.6
Stieg, P.E.7
Lipton, S.A.8
Friedlander, R.M.9
-
26
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an als transgenic mouse model
-
Li M, Ona VO, Guegan C, Chen M, Jackson-Lewis V, Andrews LJ, Olszewski AJ, Stieg PE, Lee JP, Przedborski S, Friedlander RM: Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 288:335-339, 2000.
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
Ona, V.O.2
Guegan, C.3
Chen, M.4
Jackson-Lewis, V.5
Andrews, L.J.6
Olszewski, A.J.7
Stieg, P.E.8
Lee, J.P.9
Przedborski, S.10
Friedlander, R.M.11
-
27
-
-
0032508505
-
Activation of caspase-1 in the nucleus requires nuclear translocation of pro-caspase-1 mediated by its prodomain
-
Mao PL, Jiang Y, Wee BY, Porter AG: Activation of caspase-1 in the nucleus requires nuclear translocation of pro-caspase-1 mediated by its prodomain. J Biol Chem 273:23621-23624, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 23621-23624
-
-
Mao, P.L.1
Jiang, Y.2
Wee, B.Y.3
Porter, A.G.4
-
28
-
-
0029114963
-
Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway
-
Miura M, Friedlander RM, Yuan J: Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway. Proc Natl Acad Sci U S A 92:8318-8322, 1995.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 8318-8322
-
-
Miura, M.1
Friedlander, R.M.2
Yuan, J.3
-
29
-
-
0027449187
-
Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
-
Miura M, Zhu H, Rotello R, Hartwieg EA, Yuan J: Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75:653-660, 1993.
-
(1993)
Cell
, vol.75
, pp. 653-660
-
-
Miura, M.1
Zhu, H.2
Rotello, R.3
Hartwieg, E.A.4
Yuan, J.5
-
30
-
-
0034036534
-
Apoptosis occurs after cerebral contusions in humans
-
Ng I, Yeo TT, Tang WY, Soong R, Ng PY, Smith DR: Apoptosis occurs after cerebral contusions in humans. Neurosurgery 46: 949-956, 2000.
-
(2000)
Neurosurgery
, vol.46
, pp. 949-956
-
-
Ng, I.1
Yeo, T.T.2
Tang, W.Y.3
Soong, R.4
Ng, P.Y.5
Smith, D.R.6
-
31
-
-
0034235739
-
Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons in vivo: A single-cell analysis
-
O'Dell DM, Raghupathi R, Crino PB, Eberwine JH, McIntosh TK: Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons in vivo: A single-cell analysis. J Neurosci 20:4821-4828, 2000.
-
(2000)
J Neurosci
, vol.20
, pp. 4821-4828
-
-
O'Dell, D.M.1
Raghupathi, R.2
Crino, P.B.3
Eberwine, J.H.4
McIntosh, T.K.5
-
32
-
-
0033587128
-
Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
-
Ona VO, Li M, Vonsattel JP, Andrews LJ, Khan SQ, Chung WM, Frey AS, Menon AS, Li XJ, Stieg PE, Yuan J, Penney JB, Young AB, Cha JH, Friedlander RM: Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature 399:263-267, 1999.
-
(1999)
Nature
, vol.399
, pp. 263-267
-
-
Ona, V.O.1
Li, M.2
Vonsattel, J.P.3
Andrews, L.J.4
Khan, S.Q.5
Chung, W.M.6
Frey, A.S.7
Menon, A.S.8
Li, X.J.9
Stieg, P.E.10
Yuan, J.11
Penney, J.B.12
Young, A.B.13
Cha, J.H.14
Friedlander, R.M.15
-
33
-
-
0033568011
-
A novel mechanism of action of chemically modified tetracyclines: Inhibition of COX-2-mediated prostaglandin E2 production
-
Patel RN, Attur MG, Dave MN, Patel IV, Stuchin SA, Abramson SB, Amin AR: A novel mechanism of action of chemically modified tetracyclines: Inhibition of COX-2-mediated prostaglandin E2 production. J Immunol 163:3459-3467, 1999.
-
(1999)
J Immunol
, vol.163
, pp. 3459-3467
-
-
Patel, R.N.1
Attur, M.G.2
Dave, M.N.3
Patel, I.V.4
Stuchin, S.A.5
Abramson, S.B.6
Amin, A.R.7
-
34
-
-
0034660250
-
Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines
-
Rabuffetti M, Sciorati C, Tarozzo G, Clementi E, Manfredi AA, Beltramo M: Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines. J Neurosci 20:4398-4404, 2000.
-
(2000)
J Neurosci
, vol.20
, pp. 4398-4404
-
-
Rabuffetti, M.1
Sciorati, C.2
Tarozzo, G.3
Clementi, E.4
Manfredi, A.A.5
Beltramo, M.6
-
35
-
-
0031894316
-
Reduced ischemic brain injury in interleukin-1β converting enzyme-deficient mice
-
Schielke GP, Yang GY, Shivers BD, Betz AL: Reduced ischemic brain injury in interleukin-1β converting enzyme-deficient mice. J Cereb Blood Flow Metab 18:180-185, 1998.
-
(1998)
J Cereb Blood Flow Metab
, vol.18
, pp. 180-185
-
-
Schielke, G.P.1
Yang, G.Y.2
Shivers, B.D.3
Betz, A.L.4
-
36
-
-
0031020222
-
Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury
-
Sinson G, Perri BR, Trojanowski JQ, Flamm ES, McIntosh TK: Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury. J Neurosurg 86:511-518, 1997.
-
(1997)
J Neurosurg
, vol.86
, pp. 511-518
-
-
Sinson, G.1
Perri, B.R.2
Trojanowski, J.Q.3
Flamm, E.S.4
McIntosh, T.K.5
-
37
-
-
0033028651
-
The tetracyclines
-
Smilack JD: The tetracyclines. Mayo Clin Proc 74:727-729, 1999.
-
(1999)
Mayo Clin Proc
, vol.74
, pp. 727-729
-
-
Smilack, J.D.1
-
38
-
-
0032790541
-
Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury
-
Springer JE, Azbill RD, Knapp PE: Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nat Med 5:943-946, 1999.
-
(1999)
Nat Med
, vol.5
, pp. 943-946
-
-
Springer, J.E.1
Azbill, R.D.2
Knapp, P.E.3
-
39
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Salvesen GS, Dixit VM: Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81:801-809, 1995.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
40
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry NA, Lazebnik Y: Caspases: Enemies within. Science 281:1312-1316, 1998.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
41
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes
-
Thornberry NA, Bull HG, Calaycay JR, Chapman KT, Howard AD, Kostura MJ, Miller DK, Molineaux SM, Weidner JR, Aunins J, Elliston KO, Ayala JM, Casano FJ, Chin J, Ding GJF, Egger LA, Gaffney EP, Limjuco G, Palyha OC, Raju SM, Rolando AM, Salley JP, Yamin TT, Lee TD, Shively JE, Maccross M, Mumford RA, Schmidt JA, Tocci MJ: A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature 356: 768-774, 1992.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
Elliston, K.O.11
Ayala, J.M.12
Casano, F.J.13
Chin, J.14
Ding, G.J.F.15
Egger, L.A.16
Gaffney, E.P.17
Limjuco, G.18
Palyha, O.C.19
Raju, S.M.20
Rolando, A.M.21
Salley, J.P.22
Yamin, T.T.23
Lee, T.D.24
Shively, J.E.25
Maccross, M.26
Mumford, R.A.27
Schmidt, J.A.28
Tocci, M.J.29
more..
-
42
-
-
0028888687
-
Minocycline in rheumatoid arthritis: A 48-week, double-blind, placebo-controlled trial-MIRA Trial Group
-
Tilley BC, Alarcon GS, Heyse SP, Trentham DE, Neuner R, Kaplan DA, Clegg DO, Leisen JC, Buckley L, Cooper SM: Minocycline in rheumatoid arthritis: A 48-week, double-blind, placebo-controlled trial-MIRA Trial Group Ann Intern Med 122:81-89, 1995.
-
(1995)
Ann Intern Med
, vol.122
, pp. 81-89
-
-
Tilley, B.C.1
Alarcon, G.S.2
Heyse, S.P.3
Trentham, D.E.4
Neuner, R.5
Kaplan, D.A.6
Clegg, D.O.7
Leisen, J.C.8
Buckley, L.9
Cooper, S.M.10
-
43
-
-
0029890689
-
The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation
-
Troy CM, Stefanis L, Prochiantz A, Greene LA, Shelanski ML: The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation. Proc Natl Acad Sci U S A 93:5635-5640, 1996.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5635-5640
-
-
Troy, C.M.1
Stefanis, L.2
Prochiantz, A.3
Greene, L.A.4
Shelanski, M.L.5
-
44
-
-
0028822246
-
Monitoring the impact of traumatic brain injury: A review and update
-
Waxweiler RJ, Thurman D, Sniezek J, Sosin D, O'Neil J: Monitoring the impact of traumatic brain injury: A review and update. J Neurotrauma 12:509-516, 1995.
-
(1995)
J Neurotrauma
, vol.12
, pp. 509-516
-
-
Waxweiler, R.J.1
Thurman, D.2
Sniezek, J.3
Sosin, D.4
O'Neil, J.5
-
45
-
-
0030804272
-
Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
-
Yakovlev AG, Knoblach SM, Fan L, Fox GB, Goodnight R, Faden AI: Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J Neurosci 17:7415-7424, 1997.
-
(1997)
J Neurosci
, vol.17
, pp. 7415-7424
-
-
Yakovlev, A.G.1
Knoblach, S.M.2
Fan, L.3
Fox, G.B.4
Goodnight, R.5
Faden, A.I.6
-
46
-
-
0032442475
-
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
-
Yrjanheikki J, Keinanen R, Pellikka M, Hokfelt T, Koistinaho J: Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc Natl Acad Sci U S A 95:15769-15774, 1998.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15769-15774
-
-
Yrjanheikki, J.1
Keinanen, R.2
Pellikka, M.3
Hokfelt, T.4
Koistinaho, J.5
-
47
-
-
0033539522
-
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
-
Yrjanheikki J, Tikka T, Keinanen R, Goldsteins G, Chan PH, Koistinaho J: A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc Natl Acad Sci U S A 96:13496-13500, 1999.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 13496-13500
-
-
Yrjanheikki, J.1
Tikka, T.2
Keinanen, R.3
Goldsteins, G.4
Chan, P.H.5
Koistinaho, J.6
-
48
-
-
0025255636
-
The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death
-
Yuan JY, Horvitz HR: The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev Biol 138:33-11, 1990.
-
(1990)
Dev Biol
, vol.138
, pp. 33-111
-
-
Yuan, J.Y.1
Horvitz, H.R.2
-
49
-
-
0034641936
-
Apoptosis in the nervous system
-
Yuan J, Yankner BA: Apoptosis in the nervous system. Nature 407:802-809, 2000.
-
(2000)
Nature
, vol.407
, pp. 802-809
-
-
Yuan, J.1
Yankner, B.A.2
-
50
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
-
Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR: The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75:641-652, 1993.
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
Ellis, H.M.4
Horvitz, H.R.5
-
51
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X: Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405-413, 1997.
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
52
-
-
0028025024
-
Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri
-
Zychlinsky A, Fitting C, Cavaillon JM, Sansonetti PJ: Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri. J Clin Invest 94:1328-1332, 1994.
-
(1994)
J Clin Invest
, vol.94
, pp. 1328-1332
-
-
Zychlinsky, A.1
Fitting, C.2
Cavaillon, J.M.3
Sansonetti, P.J.4
|