메뉴 건너뛰기




Volumn 48, Issue 6, 2001, Pages 1393-1401

Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction

Author keywords

Apoptosis; Caspase; Interleukin 1 ; Minocycline; Traumatic brain injury

Indexed keywords

CASPASE 3; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MINOCYCLINE;

EID: 0034998271     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-200106000-00051     Document Type: Article
Times cited : (316)

References (52)
  • 3
    • 0028179849 scopus 로고
    • Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells
    • Ankarcrona M, Dypbukt JM, Brune B, Nicotera P: Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells. Exp Cell Res 213:172-177, 1994.
    • (1994) Exp Cell Res , vol.213 , pp. 172-177
    • Ankarcrona, M.1    Dypbukt, J.M.2    Brune, B.3    Nicotera, P.4
  • 4
    • 0032839242 scopus 로고    scopus 로고
    • Current status of neuroprotection trials for traumatic brain injury: Lessons from animal models and clinical studies
    • Bullock MR, Lyeth BG, Muizelaar JP: Current status of neuroprotection trials for traumatic brain injury: Lessons from animal models and clinical studies. Neurosurgery 45:207-217, 1999.
    • (1999) Neurosurgery , vol.45 , pp. 207-217
    • Bullock, M.R.1    Lyeth, B.G.2    Muizelaar, J.P.3
  • 9
    • 0032146787 scopus 로고    scopus 로고
    • Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period
    • Conti AC, Raghupathi R, Trojanowski JQ, McIntosh TK: Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. J Neurosci 18:5663-5672, 1998.
    • (1998) J Neurosci , vol.18 , pp. 5663-5672
    • Conti, A.C.1    Raghupathi, R.2    Trojanowski, J.Q.3    McIntosh, T.K.4
  • 10
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
    • Enari M, Talanian RV, Wong WW, Nagata S: Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380:723-726, 1996.
    • (1996) Nature , vol.380 , pp. 723-726
    • Enari, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 13
    • 0031730617 scopus 로고    scopus 로고
    • ICE, neuronal apoptosis and neurodegeneration
    • Friedlander RM, Yuan J: ICE, neuronal apoptosis and neurodegeneration. Cell Death Differ 5:823-831, 1998.
    • (1998) Cell Death Differ , vol.5 , pp. 823-831
    • Friedlander, R.M.1    Yuan, J.2
  • 15
    • 8044252166 scopus 로고    scopus 로고
    • Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury
    • Friedlander RM, Gagliardini V, Hara H, Fink KB, Li W, MacDonald G, Fishman MC, Greenberg AH, Moskowitz MA, Yuan J: Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med 185:933-940, 1997.
    • (1997) J Exp Med , vol.185 , pp. 933-940
    • Friedlander, R.M.1    Gagliardini, V.2    Hara, H.3    Fink, K.B.4    Li, W.5    MacDonald, G.6    Fishman, M.C.7    Greenberg, A.H.8    Moskowitz, M.A.9    Yuan, J.10
  • 16
    • 0029788702 scopus 로고    scopus 로고
    • Functional role of interleukin 1β (IL-1β) in IL-1β-converting enzyme-mediated apoptosis
    • Friedlander RM, Gagliardini V, Rotello RJ, Yuan J: Functional role of interleukin 1β (IL-1β) in IL-1β-converting enzyme-mediated apoptosis. J Exp Med 184:717-724, 1996.
    • (1996) J Exp Med , vol.184 , pp. 717-724
    • Friedlander, R.M.1    Gagliardini, V.2    Rotello, R.J.3    Yuan, J.4
  • 17
    • 0034626090 scopus 로고    scopus 로고
    • Traumatic brain injury
    • Ghajar J: Traumatic brain injury. Lancet 356:923-929, 2000.
    • (2000) Lancet , vol.356 , pp. 923-929
    • Ghajar, J.1
  • 20
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO: The biochemistry of apoptosis. Nature 407:770-776, 2000.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 22
    • 0033970987 scopus 로고    scopus 로고
    • Intracerebral administration of interleukin-1β and induction of inflammation, apoptosis, and vasogenic edema
    • Holmin S, Mathiesen T: Intracerebral administration of interleukin-1β and induction of inflammation, apoptosis, and vasogenic edema. J Neurosurg 92:108-120, 2000.
    • (2000) J Neurosurg , vol.92 , pp. 108-120
    • Holmin, S.1    Mathiesen, T.2
  • 24
    • 0033601995 scopus 로고    scopus 로고
    • Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity
    • Klevenyi P, Andreassen O, Ferrante RJ, Schleicher JR Jr, Friedlander RM, Beal MF: Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity. Neuroreport 10:635-638, 1999.
    • (1999) Neuroreport , vol.10 , pp. 635-638
    • Klevenyi, P.1    Andreassen, O.2    Ferrante, R.J.3    Schleicher J., Jr.4    Friedlander, R.M.5    Beal, M.F.6
  • 25
    • 0034638259 scopus 로고    scopus 로고
    • Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury
    • Li M, Ona VO, Chen M, Kaul M, Tenneti L, Zhang X, Stieg PE, Lipton SA, Friedlander RM: Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury. Neuroscience 99:333-342, 2000.
    • (2000) Neuroscience , vol.99 , pp. 333-342
    • Li, M.1    Ona, V.O.2    Chen, M.3    Kaul, M.4    Tenneti, L.5    Zhang, X.6    Stieg, P.E.7    Lipton, S.A.8    Friedlander, R.M.9
  • 27
    • 0032508505 scopus 로고    scopus 로고
    • Activation of caspase-1 in the nucleus requires nuclear translocation of pro-caspase-1 mediated by its prodomain
    • Mao PL, Jiang Y, Wee BY, Porter AG: Activation of caspase-1 in the nucleus requires nuclear translocation of pro-caspase-1 mediated by its prodomain. J Biol Chem 273:23621-23624, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 23621-23624
    • Mao, P.L.1    Jiang, Y.2    Wee, B.Y.3    Porter, A.G.4
  • 28
    • 0029114963 scopus 로고
    • Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway
    • Miura M, Friedlander RM, Yuan J: Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway. Proc Natl Acad Sci U S A 92:8318-8322, 1995.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8318-8322
    • Miura, M.1    Friedlander, R.M.2    Yuan, J.3
  • 29
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
    • Miura M, Zhu H, Rotello R, Hartwieg EA, Yuan J: Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75:653-660, 1993.
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwieg, E.A.4    Yuan, J.5
  • 31
    • 0034235739 scopus 로고    scopus 로고
    • Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons in vivo: A single-cell analysis
    • O'Dell DM, Raghupathi R, Crino PB, Eberwine JH, McIntosh TK: Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons in vivo: A single-cell analysis. J Neurosci 20:4821-4828, 2000.
    • (2000) J Neurosci , vol.20 , pp. 4821-4828
    • O'Dell, D.M.1    Raghupathi, R.2    Crino, P.B.3    Eberwine, J.H.4    McIntosh, T.K.5
  • 33
    • 0033568011 scopus 로고    scopus 로고
    • A novel mechanism of action of chemically modified tetracyclines: Inhibition of COX-2-mediated prostaglandin E2 production
    • Patel RN, Attur MG, Dave MN, Patel IV, Stuchin SA, Abramson SB, Amin AR: A novel mechanism of action of chemically modified tetracyclines: Inhibition of COX-2-mediated prostaglandin E2 production. J Immunol 163:3459-3467, 1999.
    • (1999) J Immunol , vol.163 , pp. 3459-3467
    • Patel, R.N.1    Attur, M.G.2    Dave, M.N.3    Patel, I.V.4    Stuchin, S.A.5    Abramson, S.B.6    Amin, A.R.7
  • 34
    • 0034660250 scopus 로고    scopus 로고
    • Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines
    • Rabuffetti M, Sciorati C, Tarozzo G, Clementi E, Manfredi AA, Beltramo M: Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines. J Neurosci 20:4398-4404, 2000.
    • (2000) J Neurosci , vol.20 , pp. 4398-4404
    • Rabuffetti, M.1    Sciorati, C.2    Tarozzo, G.3    Clementi, E.4    Manfredi, A.A.5    Beltramo, M.6
  • 35
    • 0031894316 scopus 로고    scopus 로고
    • Reduced ischemic brain injury in interleukin-1β converting enzyme-deficient mice
    • Schielke GP, Yang GY, Shivers BD, Betz AL: Reduced ischemic brain injury in interleukin-1β converting enzyme-deficient mice. J Cereb Blood Flow Metab 18:180-185, 1998.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 180-185
    • Schielke, G.P.1    Yang, G.Y.2    Shivers, B.D.3    Betz, A.L.4
  • 36
    • 0031020222 scopus 로고    scopus 로고
    • Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury
    • Sinson G, Perri BR, Trojanowski JQ, Flamm ES, McIntosh TK: Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury. J Neurosurg 86:511-518, 1997.
    • (1997) J Neurosurg , vol.86 , pp. 511-518
    • Sinson, G.1    Perri, B.R.2    Trojanowski, J.Q.3    Flamm, E.S.4    McIntosh, T.K.5
  • 37
    • 0033028651 scopus 로고    scopus 로고
    • The tetracyclines
    • Smilack JD: The tetracyclines. Mayo Clin Proc 74:727-729, 1999.
    • (1999) Mayo Clin Proc , vol.74 , pp. 727-729
    • Smilack, J.D.1
  • 38
    • 0032790541 scopus 로고    scopus 로고
    • Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury
    • Springer JE, Azbill RD, Knapp PE: Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nat Med 5:943-946, 1999.
    • (1999) Nat Med , vol.5 , pp. 943-946
    • Springer, J.E.1    Azbill, R.D.2    Knapp, P.E.3
  • 39
    • 0028990125 scopus 로고
    • Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Salvesen GS, Dixit VM: Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81:801-809, 1995.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 40
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y: Caspases: Enemies within. Science 281:1312-1316, 1998.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 43
    • 0029890689 scopus 로고    scopus 로고
    • The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation
    • Troy CM, Stefanis L, Prochiantz A, Greene LA, Shelanski ML: The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation. Proc Natl Acad Sci U S A 93:5635-5640, 1996.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5635-5640
    • Troy, C.M.1    Stefanis, L.2    Prochiantz, A.3    Greene, L.A.4    Shelanski, M.L.5
  • 45
    • 0030804272 scopus 로고    scopus 로고
    • Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
    • Yakovlev AG, Knoblach SM, Fan L, Fox GB, Goodnight R, Faden AI: Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J Neurosci 17:7415-7424, 1997.
    • (1997) J Neurosci , vol.17 , pp. 7415-7424
    • Yakovlev, A.G.1    Knoblach, S.M.2    Fan, L.3    Fox, G.B.4    Goodnight, R.5    Faden, A.I.6
  • 47
    • 0033539522 scopus 로고    scopus 로고
    • A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
    • Yrjanheikki J, Tikka T, Keinanen R, Goldsteins G, Chan PH, Koistinaho J: A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc Natl Acad Sci U S A 96:13496-13500, 1999.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 13496-13500
    • Yrjanheikki, J.1    Tikka, T.2    Keinanen, R.3    Goldsteins, G.4    Chan, P.H.5    Koistinaho, J.6
  • 48
    • 0025255636 scopus 로고
    • The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death
    • Yuan JY, Horvitz HR: The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev Biol 138:33-11, 1990.
    • (1990) Dev Biol , vol.138 , pp. 33-111
    • Yuan, J.Y.1    Horvitz, H.R.2
  • 49
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J, Yankner BA: Apoptosis in the nervous system. Nature 407:802-809, 2000.
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 50
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
    • Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR: The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75:641-652, 1993.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 51
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H, Henzel WJ, Liu X, Lutschg A, Wang X: Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405-413, 1997.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 52
    • 0028025024 scopus 로고
    • Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri
    • Zychlinsky A, Fitting C, Cavaillon JM, Sansonetti PJ: Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri. J Clin Invest 94:1328-1332, 1994.
    • (1994) J Clin Invest , vol.94 , pp. 1328-1332
    • Zychlinsky, A.1    Fitting, C.2    Cavaillon, J.M.3    Sansonetti, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.