A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 23, 1999, Pages 13496-13500

  Yrjänheikki, Juha ^a,b   Tikka, Tiina ^b   Keinänen, Riitta ^b   Goldsteins, Gundars ^b   Chan, Pak H ^a   Koistinaho, Jari ^a,b,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

MINOCYCLINE; TETRACYCLINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN ISCHEMIA; BRAIN PROTECTION; DRUG EFFECT; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BASE SEQUENCE; BRAIN ISCHEMIA; CYCLOOXYGENASE 2; DINOPROSTONE; DNA PRIMERS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; ISOENZYMES; MALE; MINOCYCLINE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE;

ANIMALIA;

EID: 0033539522     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.23.13496     Document Type: Article

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