Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 26, 1998, Pages 15769-15774

  Yrjänheikki, Juha ^a   Keinänen, Riitta ^a   Pellikka, Milla ^a   Hökfelt, Tomas ^c   Koistinaho, Jari ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CASPASE; DOXYCYCLINE; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; MINOCYCLINE; NITRIC OXIDE SYNTHASE; TETRACYCLINE; TETRACYCLINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTOSIS; BRAIN ISCHEMIA; BRAIN PROTECTION; CELL ACTIVATION; CELL SURVIVAL; CEREBROVASCULAR ACCIDENT; DRUG ACTIVITY; DRUG EFFECT; GERBIL; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL;

ANIMALS; DOXYCYCLINE; GERBILLINAE; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; HUMANS; ISCHEMIC ATTACK, TRANSIENT; MALE; MICROGLIA; MINOCYCLINE; NEUROPROTECTIVE AGENTS; PYRAMIDAL CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRACYCLINES; TRANSCRIPTION, GENETIC;

EID: 0032442475     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.26.15769     Document Type: Article

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