메뉴 건너뛰기




Volumn 160, Issue 1, 1999, Pages 226-234

Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury

Author keywords

Cortied contusion; Mitochondrial dysfunction; Trauma

Indexed keywords

CALCIUM; CYCLOSPORIN A; REACTIVE OXYGEN METABOLITE;

EID: 0032736595     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1999.7197     Document Type: Article
Times cited : (296)

References (82)
  • 1
    • 0026559373 scopus 로고
    • Do NMDA antagonists prevent neuronal injury? Yes
    • Albers G. W., Goldberg M. P., Choi D. W. Do NMDA antagonists prevent neuronal injury? Yes. Arch. Neurol. 49:1992;418-420.
    • (1992) Arch. Neurol. , vol.49 , pp. 418-420
    • Albers, G.W.1    Goldberg, M.P.2    Choi, D.W.3
  • 2
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M., Dypbukt J. M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S. A., Nicotera P. Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:1995;961-973.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 3
    • 0030574021 scopus 로고    scopus 로고
    • Calcineurin and mitochondrial function in glutamate-induced neuronal cell death
    • Ankarcrona M., Dypbukt J. M., Orrenius S., Nicotera P. Calcineurin and mitochondrial function in glutamate-induced neuronal cell death. FEBS Lett. 394:1996;321-324.
    • (1996) FEBS Lett. , vol.394 , pp. 321-324
    • Ankarcrona, M.1    Dypbukt, J.M.2    Orrenius, S.3    Nicotera, P.4
  • 5
    • 0030833621 scopus 로고    scopus 로고
    • Neuronal cell loss in the CA3 subfield of the hippocampus following cortical contusion utilizing the optical disector method for cell counting
    • Baldwin S. A., Gibson T., Callihan C. T., Sullivan P. G., Palmer E., Scheff S. W. Neuronal cell loss in the CA3 subfield of the hippocampus following cortical contusion utilizing the optical disector method for cell counting. J. Neurotrauma. 14:1997;385-398.
    • (1997) J. Neurotrauma , vol.14 , pp. 385-398
    • Baldwin, S.A.1    Gibson, T.2    Callihan, C.T.3    Sullivan, P.G.4    Palmer, E.5    Scheff, S.W.6
  • 6
    • 0030106237 scopus 로고    scopus 로고
    • Intermediate filament change in astrocytes following mild cortical contusion
    • Baldwin S. A., Scheff S. W. Intermediate filament change in astrocytes following mild cortical contusion. Glia. 16:1996;266-275.
    • (1996) Glia , vol.16 , pp. 266-275
    • Baldwin, S.A.1    Scheff, S.W.2
  • 7
    • 0030592172 scopus 로고    scopus 로고
    • The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death
    • Bernardi P. The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death. Biochim. Biophys. Acta. 1275:1996;5-9.
    • (1996) Biochim. Biophys. Acta , vol.1275 , pp. 5-9
    • Bernardi, P.1
  • 8
    • 0028053663 scopus 로고
    • Recent progress on regulation of the mitochondrial permeability transition pore: A cyclosporin-sensitive pore in the inner mitochondrial membrane
    • Bernardi P., Broekemeier K. M., Pfeiffer D. R. Recent progress on regulation of the mitochondrial permeability transition pore: A cyclosporin-sensitive pore in the inner mitochondrial membrane. J. Bioenerg. Biomembr. 26:1994;509-517.
    • (1994) J. Bioenerg. Biomembr. , vol.26 , pp. 509-517
    • Bernardi, P.1    Broekemeier, K.M.2    Pfeiffer, D.R.3
  • 9
    • 0029998621 scopus 로고    scopus 로고
    • The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal
    • Bernardi P., Petronilli V. The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal. J. Bioenerg. Biomembr. 28:1996;131-138.
    • (1996) J. Bioenerg. Biomembr. , vol.28 , pp. 131-138
    • Bernardi, P.1    Petronilli, V.2
  • 10
    • 0022189554 scopus 로고
    • Interaction of lipid peroxidation and calcium in the pathogenesis of neuronal injury
    • Braughler J. M., Duncan L. A., Chase R. L. Interaction of lipid peroxidation and calcium in the pathogenesis of neuronal injury. Cent. Nerv. Syst. Trauma. 2:1985;269-283.
    • (1985) Cent. Nerv. Syst. Trauma , vol.2 , pp. 269-283
    • Braughler, J.M.1    Duncan, L.A.2    Chase, R.L.3
  • 11
    • 0024520513 scopus 로고
    • Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation
    • Braughler J. M., Hall E. D. Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Radical. Biol. Med. 6:1989;289-301.
    • (1989) Free Radical. Biol. Med. , vol.6 , pp. 289-301
    • Braughler, J.M.1    Hall, E.D.2
  • 12
    • 0026544582 scopus 로고
    • Involvement of lipid peroxidation in CNS injury
    • Braughler J. M., Hall E. D. Involvement of lipid peroxidation in CNS injury. J. Neurotrauma. 9:1992;S1-S7.
    • (1992) J. Neurotrauma , vol.9
    • Braughler, J.M.1    Hall, E.D.2
  • 13
    • 0024360271 scopus 로고
    • Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria
    • Broekemeier K. M., Dempsey M. E., Pfeiffer D. R. Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J. Biol. Chem. 264:1989;7826-7830.
    • (1989) J. Biol. Chem. , vol.264 , pp. 7826-7830
    • Broekemeier, K.M.1    Dempsey, M.E.2    Pfeiffer, D.R.3
  • 14
    • 0029561991 scopus 로고
    • Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments; Relationship between pore opening and the activity of mitochondrial phospholipases
    • Broekemeier K. M., Pfeiffer D. R. Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments; Relationship between pore opening and the activity of mitochondrial phospholipases. Biochemistry. 34:1995;16440-16449.
    • (1995) Biochemistry , vol.34 , pp. 16440-16449
    • Broekemeier, K.M.1    Pfeiffer, D.R.2
  • 15
    • 0031970112 scopus 로고    scopus 로고
    • Peroxynitrite and brain mitochondria: Evidence for increased proton leak
    • Brookes P. S., Land J. M., Clark J. B., Heales S. J. R. Peroxynitrite and brain mitochondria: Evidence for increased proton leak. J. Neurochem. 70:1998;2195-2202.
    • (1998) J. Neurochem. , vol.70 , pp. 2195-2202
    • Brookes, P.S.1    Land, J.M.2    Clark, J.B.3    Heales, S.J.R.4
  • 17
    • 0030071252 scopus 로고    scopus 로고
    • A reevaluation of the role of mitochondria in neuronal Ca2+ homeostasis
    • Budd S. L., Nicholls D. G. A reevaluation of the role of mitochondria in neuronal Ca2+ homeostasis. J. Neurochem. 66:1996;403-411.
    • (1996) J. Neurochem. , vol.66 , pp. 403-411
    • Budd, S.L.1    Nicholls, D.G.2
  • 18
    • 0031589693 scopus 로고    scopus 로고
    • Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: Role of arachidonic acid
    • Camins A., Sureda F. X., Gabriel C., Pallas M., Escubedo E., Camarasa J. Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: role of arachidonic acid. Brain Res. 777:1997;69-74.
    • (1997) Brain Res. , vol.777 , pp. 69-74
    • Camins, A.1    Sureda, F.X.2    Gabriel, C.3    Pallas, M.4    Escubedo, E.5    Camarasa, J.6
  • 19
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi D. W. Excitotoxic cell death. J. Neurobiol. 23:1992;1261-1276.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 20
    • 0025552849 scopus 로고
    • Acute brain injury, NMDA receptors, and hydrogen ions: Observations in cortical cell cultures
    • Choi D. W., Monyer H., Giffard R. G., Goldberg M. P., Christine C. W. Acute brain injury, NMDA receptors, and hydrogen ions: observations in cortical cell cultures. Adv. Exp. Med. Biol. 268:1990;501-504.
    • (1990) Adv. Exp. Med. Biol. , vol.268 , pp. 501-504
    • Choi, D.W.1    Monyer, H.2    Giffard, R.G.3    Goldberg, M.P.4    Christine, C.W.5
  • 21
    • 0003040647 scopus 로고
    • Delayed brain injury: Secondary insults
    • J. Povlishhock, & D. Becker. Washington: National Institutes of Health
    • Cooper P. Delayed brain injury: Secondary insults. Povlishhock J., Becker D. Central Nervous System Trauma Status Report. 1985;217-282 National Institutes of Health, Washington.
    • (1985) Central Nervous System Trauma Status Report , pp. 217-282
    • Cooper, P.1
  • 22
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neuronal degenerative disorders
    • Coyle J. T., Puttfarcken P. Oxidative stress, glutamate, and neuronal degenerative disorders. Science. 262:1993;689-695.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 23
    • 0029909742 scopus 로고    scopus 로고
    • Immunosuppressants, immunophilins, and the nervous system
    • Dawson T. M. Immunosuppressants, immunophilins, and the nervous system. Ann. Neurol. 40:1996;559-560.
    • (1996) Ann. Neurol. , vol.40 , pp. 559-560
    • Dawson, T.M.1
  • 24
    • 0027178135 scopus 로고
    • Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures
    • Dawson V. L., Dawson T. M., Barley D. A., Uhl G. R., Snyder S. H. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci. 13:1993;2651-2661.
    • (1993) J. Neurosci. , vol.13 , pp. 2651-2661
    • Dawson, V.L.1    Dawson, T.M.2    Barley, D.A.3    Uhl, G.R.4    Snyder, S.H.5
  • 25
    • 0028882282 scopus 로고
    • Ruthenium red protects against glutamate-induced neuronal death in cerebellar culture
    • Dessi F., Ben-Ari Y., Charriaut-Marlangue C. Ruthenium red protects against glutamate-induced neuronal death in cerebellar culture. Neurosci. Lett. 201:1995;53-56.
    • (1995) Neurosci. Lett. , vol.201 , pp. 53-56
    • Dessi, F.1    Ben-Ari, Y.2    Charriaut-Marlangue, C.3
  • 26
    • 0032530326 scopus 로고    scopus 로고
    • Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons
    • Dubinsky J. M., Levi Y. Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons. J. Neurosci. Res. 53:1998;728-741.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 728-741
    • Dubinsky, J.M.1    Levi, Y.2
  • 28
    • 0023220472 scopus 로고
    • Calcium in the mitochondria following brief ischemia of gerbil brain
    • Dux E., Mies G., Hossmann K.-A., Siklos L. Calcium in the mitochondria following brief ischemia of gerbil brain. Neurosci. Lett. 78:1987;295-300.
    • (1987) Neurosci. Lett. , vol.78 , pp. 295-300
    • Dux, E.1    Mies, G.2    Hossmann, K.-A.3    Siklos, L.4
  • 29
    • 0027884838 scopus 로고
    • Experimental neurobiology of central nervous system trauma
    • Faden A. I. Experimental neurobiology of central nervous system trauma. Crit. Rev. Neurobiol. 7:1993;175-186.
    • (1993) Crit. Rev. Neurobiol. , vol.7 , pp. 175-186
    • Faden, A.I.1
  • 30
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden A. I., Demediuk P., Panter S. S., Vink R. The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science. 244:1989;798-800.
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 31
    • 0030959940 scopus 로고    scopus 로고
    • Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects
    • Folbergrova J., Li P. A., Uchino H., Smith M.-L., Siesjo B. K. Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects. Exp. Brain Res. 114:1997;44-50.
    • (1997) Exp. Brain Res. , vol.114 , pp. 44-50
    • Folbergrova, J.1    Li, P.A.2    Uchino, H.3    Smith, M.-L.4    Siesjo, B.K.5
  • 32
    • 0032528154 scopus 로고    scopus 로고
    • Cyclosporin A, but not Fk 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death
    • Friberg H., Ferrand-Drake M., Bengtsson F., Halestrap A. P., Wieloch T. Cyclosporin A, but not Fk 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J. Neurosci. 18:1998;5151-5159.
    • (1998) J. Neurosci. , vol.18 , pp. 5151-5159
    • Friberg, H.1    Ferrand-Drake, M.2    Bengtsson, F.3    Halestrap, A.P.4    Wieloch, T.5
  • 33
    • 0025831980 scopus 로고
    • Two cytoplasmic candidates for immunophilin action are related by affinity for a new cyclophilin: One in the presence and one in the absence of CsA
    • Friedman J., Weissman I. Two cytoplasmic candidates for immunophilin action are related by affinity for a new cyclophilin: One in the presence and one in the absence of CsA. Cell. 66:1991;799-806.
    • (1991) Cell , vol.66 , pp. 799-806
    • Friedman, J.1    Weissman, I.2
  • 34
    • 0028095807 scopus 로고
    • Mitochondrial calcium transport: Physiological and pathological relevance
    • Gunter T. E., Gunter K. K., Sheu S., Gavin C. E. Mitochondrial calcium transport: Physiological and pathological relevance. Am. J. Physiol. 267:1994;C313-C339.
    • (1994) Am. J. Physiol. , vol.267
    • Gunter, T.E.1    Gunter, K.K.2    Sheu, S.3    Gavin, C.E.4
  • 35
    • 0029281830 scopus 로고
    • [The toxic effect of glutamate causes mitochondrial damage in dissociated cultures of cerebellar granules]
    • Isaev N. K., Uzbekov R. E., Zorov D. B., Stel'Mashuk E. V., Viktorov I. V. [The toxic effect of glutamate causes mitochondrial damage in dissociated cultures of cerebellar granules]. Biull. Eksp. Biol. Med. 119:1995;378-380.
    • (1995) Biull. Eksp. Biol. Med. , vol.119 , pp. 378-380
    • Isaev, N.K.1    Uzbekov, R.E.2    Zorov, D.B.3    Stel'Mashuk, E.V.4    Viktorov, I.V.5
  • 36
    • 0030603110 scopus 로고    scopus 로고
    • Neurotoxic glutamate treatment of cultured cerebellar granule cells induces Ca2+-dependent collapse of mitochondrial membrane potential and ultrastructural alterations of mitochondria
    • Isaev N. K., Zorov D. B., Stelmashook E. V., Uzbekov R. E., Kozhemyakin M. B., Victorov I. V. Neurotoxic glutamate treatment of cultured cerebellar granule cells induces Ca2+-dependent collapse of mitochondrial membrane potential and ultrastructural alterations of mitochondria. FEBS Lett. 392:1996;143-147.
    • (1996) FEBS Lett. , vol.392 , pp. 143-147
    • Isaev, N.K.1    Zorov, D.B.2    Stelmashook, E.V.3    Uzbekov, R.E.4    Kozhemyakin, M.B.5    Victorov, I.V.6
  • 37
    • 0030754962 scopus 로고    scopus 로고
    • 4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes
    • Keller J. N., Mark R. J., Bruce A. J., Blanc E., Rothstein J. D., Uchida K., Waeg G., Mattson M. P. 4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes. Neuroscience. 80:1997;685-696.
    • (1997) Neuroscience , vol.80 , pp. 685-696
    • Keller, J.N.1    Mark, R.J.2    Bruce, A.J.3    Blanc, E.4    Rothstein, J.D.5    Uchida, K.6    Waeg, G.7    Mattson, M.P.8
  • 38
    • 0001935057 scopus 로고    scopus 로고
    • Epidemiology of head injury
    • R. K. Narayan, J. E. Wilberger, & J. T. Povlishock. New York: McGraw-Hill
    • Kraus J. F. Epidemiology of head injury. Narayan R. K., Wilberger J. E., Povlishock J. T. Neurotrauma. 1996;12-30 McGraw-Hill, New York.
    • (1996) Neurotrauma , pp. 12-30
    • Kraus, J.F.1
  • 39
    • 0030800033 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in the central nervous system: Induction by calcium cycling-dependent and -independent pathways
    • Kristal B. S., Dubinsky J. M. Mitochondrial permeability transition in the central nervous system: Induction by calcium cycling-dependent and -independent pathways. J. Neurochem. 69:1997;524-538.
    • (1997) J. Neurochem. , vol.69 , pp. 524-538
    • Kristal, B.S.1    Dubinsky, J.M.2
  • 40
    • 0031953601 scopus 로고    scopus 로고
    • Calcium in ischemic cell death
    • Kristian T., Siesjo B. K. Calcium in ischemic cell death. Stroke. 29:1998;705-718.
    • (1998) Stroke , vol.29 , pp. 705-718
    • Kristian, T.1    Siesjo, B.K.2
  • 41
    • 0030951890 scopus 로고    scopus 로고
    • Amelioration by cyclosporin A of brain damage following 5 or 10 min of ischemia in rats subjected to preischemic hyperglycemia
    • Li P. A., Uchino H., Elmer E., Siesjo B. K. Amelioration by cyclosporin A of brain damage following 5 or 10 min of ischemia in rats subjected to preischemic hyperglycemia. Brain Res. 753:1997;133-140.
    • (1997) Brain Res. , vol.753 , pp. 133-140
    • Li, P.A.1    Uchino, H.2    Elmer, E.3    Siesjo, B.K.4
  • 42
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu J., Farmer J. D., Lane W. S., Friedman J., Weissman I., Schreiber S. L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell. 66:1991;807-815.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 43
    • 0029175202 scopus 로고
    • Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
    • Mattson M. P., Barger S. W., Begley J. G., Mark R. J. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol. 46:1995;187-216.
    • (1995) Methods Cell Biol. , vol.46 , pp. 187-216
    • Mattson, M.P.1    Barger, S.W.2    Begley, J.G.3    Mark, R.J.4
  • 45
    • 0028218770 scopus 로고
    • Endogenous neuroprotection factors and traumatic brain injury: Mechanisms of action and implications for therapy
    • Mattson M. P., Scheff S. W. Endogenous neuroprotection factors and traumatic brain injury: Mechanisms of action and implications for therapy. J. Neurotrauma. 11:1994;3-33.
    • (1994) J. Neurotrauma , vol.11 , pp. 3-33
    • Mattson, M.P.1    Scheff, S.W.2
  • 46
    • 0027377278 scopus 로고
    • Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: A review
    • McIntosh T. K. Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: A review. J. Neurotrauma. 10:1993;215-261.
    • (1993) J. Neurotrauma , vol.10 , pp. 215-261
    • McIntosh, T.K.1
  • 47
    • 0031766138 scopus 로고    scopus 로고
    • Novel pharmacologic strategies in the treatment of experimental traumatic brain injury: 1998
    • McIntosh T. K., Juhler M., Wieloch T. Novel pharmacologic strategies in the treatment of experimental traumatic brain injury: 1998. J. Neurotrauma. 15:1998;731-769.
    • (1998) J. Neurotrauma. , vol.15 , pp. 731-769
    • McIntosh, T.K.1    Juhler, M.2    Wieloch, T.3
  • 48
    • 0022333161 scopus 로고
    • A role for the mitochondrion in the protection of cells against calcium overload
    • Nicholls D. G. A role for the mitochondrion in the protection of cells against calcium overload. Prog. Brain Res. 63:1985;97-106.
    • (1985) Prog. Brain Res. , vol.63 , pp. 97-106
    • Nicholls, D.G.1
  • 49
    • 0032504708 scopus 로고    scopus 로고
    • Mitochondria and neuronal glutamate excitotoxicity
    • Nicholls D. G., Budd S. L. Mitochondria and neuronal glutamate excitotoxicity. Biochim. Biophys. Acta. 1366:1998;97-112.
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 97-112
    • Nicholls, D.G.1    Budd, S.L.2
  • 50
    • 0030051609 scopus 로고    scopus 로고
    • Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, a cyclosporin A-sensitive channel
    • Nicoll A., Basso E., Petronilli V., Wenger R. M., Bernardi P. Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, a cyclosporin A-sensitive channel. J. Biol. Chem. 271:1996;2185-2192.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2185-2192
    • Nicoll, A.1    Basso, E.2    Petronilli, V.3    Wenger, R.M.4    Bernardi, P.5
  • 51
    • 0030298459 scopus 로고    scopus 로고
    • Cyclosporin A delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: Evidence of the mitochondrial permeability transition
    • Nieminen A.-L., Petrie T. G., LeMasters J. J., Selman W. R. Cyclosporin A delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: Evidence of the mitochondrial permeability transition. Neuroscience. 75:1996;993-997.
    • (1996) Neuroscience , vol.75 , pp. 993-997
    • Nieminen, A.-L.1    Petrie, T.G.2    Lemasters, J.J.3    Selman, W.R.4
  • 52
    • 0033525008 scopus 로고    scopus 로고
    • Cyclosporin A limits calcium-induced axonal damage following traumatic brain injury
    • Okonkwo D. O., Buki A., Siman R., Povlishock J. T. Cyclosporin A limits calcium-induced axonal damage following traumatic brain injury. Neuroreport. 10:1999;1-6.
    • (1999) Neuroreport , vol.10 , pp. 1-6
    • Okonkwo, D.O.1    Buki, A.2    Siman, R.3    Povlishock, J.T.4
  • 53
    • 0033509493 scopus 로고    scopus 로고
    • A single intrathecal bolus of cyclosporin. A before injury preserves mitochondrial integrity and attenuates axonal disruption following traumatic brain injury
    • Okonkwo D. O., Povlishock J. T. A single intrathecal bolus of cyclosporin. A before injury preserves mitochondrial integrity and attenuates axonal disruption following traumatic brain injury. J. Cereb. Blood Flow. Metab. 19:1999;443-451.
    • (1999) J. Cereb. Blood Flow. Metab. , vol.19 , pp. 443-451
    • Okonkwo, D.O.1    Povlishock, J.T.2
  • 54
    • 0029074513 scopus 로고
    • Nitric oxide in the central nervous system
    • Paakkari I., Lindsberg P. Nitric oxide in the central nervous system. Ann. Med. 27:1995;369-377.
    • (1995) Ann. Med. , vol.27 , pp. 369-377
    • Paakkari, I.1    Lindsberg, P.2
  • 55
    • 0026542415 scopus 로고
    • Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury
    • Panter S. S., Faden A. I. Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury. Neurosci. Lett. 136:1992;165-168.
    • (1992) Neurosci. Lett. , vol.136 , pp. 165-168
    • Panter, S.S.1    Faden, A.I.2
  • 56
    • 0031891837 scopus 로고    scopus 로고
    • Mitochondrial transmembrane potential and free radical production in excitotoxic neurodegeneration
    • Prehn J. H. Mitochondrial transmembrane potential and free radical production in excitotoxic neurodegeneration. Naunyn Schmiedebergs Arch. Pharmacol. 357:1998;316-322.
    • (1998) Naunyn Schmiedebergs Arch. Pharmacol. , vol.357 , pp. 316-322
    • Prehn, J.H.1
  • 57
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • Reynolds I. J., Hastings T. G. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15:1995;3318-3327.
    • (1995) J. Neurosci. , vol.15 , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, T.G.2
  • 58
    • 0030976163 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen species regulate mitochondrial Ca2+ homeostasis and respiration
    • Richter C. Reactive oxygen and nitrogen species regulate mitochondrial Ca2+ homeostasis and respiration. Biosci. Rep. 17:1997;53-66.
    • (1997) Biosci. Rep. , vol.17 , pp. 53-66
    • Richter, C.1
  • 59
    • 0031797319 scopus 로고    scopus 로고
    • Effects of oxidants and glutamate receptor activation on mitochondrial membrane potential in rat forebrain neurons
    • Scanlon J. M., Reynolds I. J. Effects of oxidants and glutamate receptor activation on mitochondrial membrane potential in rat forebrain neurons. J. Neurochem. 71:1998;2392-2400.
    • (1998) J. Neurochem. , vol.71 , pp. 2392-2400
    • Scanlon, J.M.1    Reynolds, I.J.2
  • 60
    • 0030820401 scopus 로고    scopus 로고
    • Morris water maze deficits in rats following traumatic brain injury: Lateral controlled cortical impact
    • Scheff S. W., Baldwin S. A., Brown R. W., Kraemer P. J. Morris water maze deficits in rats following traumatic brain injury: Lateral controlled cortical impact. J. Neurotrauma. 14:1997;615-627.
    • (1997) J. Neurotrauma , vol.14 , pp. 615-627
    • Scheff, S.W.1    Baldwin, S.A.2    Brown, R.W.3    Kraemer, P.J.4
  • 61
    • 0032878575 scopus 로고    scopus 로고
    • Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents
    • Scheff S. W., Sullivan P. G. Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents. J. Neurotrauma. 16:1999;783-792.
    • (1999) J. Neurotrauma. , vol.16 , pp. 783-792
    • Scheff, S.W.1    Sullivan, P.G.2
  • 62
    • 0029810095 scopus 로고    scopus 로고
    • Mitochondrial dysfunction is a primary event in glutamate neurotoxicity
    • Schinder A. F., Spitzer N. C., Montal M. Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J. Neurosci. 16:1996;6125-6133.
    • (1996) J. Neurosci. , vol.16 , pp. 6125-6133
    • Schinder, A.F.1    Spitzer, N.C.2    Montal, M.3
  • 63
    • 0031869004 scopus 로고    scopus 로고
    • NMDA-induced superoxide production and neurotoxicity in cultured rat hippocampal neurons: Role of mitochondria
    • Sengpiel B., Preis E., Krieglstein J., Prehn J. H. NMDA-induced superoxide production and neurotoxicity in cultured rat hippocampal neurons: Role of mitochondria. Eur. J. Neurosci. 10:1998;1903-1910.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1903-1910
    • Sengpiel, B.1    Preis, E.2    Krieglstein, J.3    Prehn, J.H.4
  • 64
    • 0026446691 scopus 로고
    • Cyclosporin A protects against ischemia-reperfusion injury in the brain
    • Shiga Y., Onodera H., Matsuo Y., Kogure K. Cyclosporin A protects against ischemia-reperfusion injury in the brain. Brain Res. 595:1992;145-148.
    • (1992) Brain Res. , vol.595 , pp. 145-148
    • Shiga, Y.1    Onodera, H.2    Matsuo, Y.3    Kogure, K.4
  • 66
    • 0023616754 scopus 로고
    • Altered mitochondrial respiration in selectively vulnerable brain subregions following transient forebrain ischemia in the rat
    • Sims N., Pulsinelli W. Altered mitochondrial respiration in selectively vulnerable brain subregions following transient forebrain ischemia in the rat. J. Neurochem. 49:1987;1367-1374.
    • (1987) J. Neurochem. , vol.49 , pp. 1367-1374
    • Sims, N.1    Pulsinelli, W.2
  • 67
    • 0032535398 scopus 로고    scopus 로고
    • Thiol oxidation and loss of mitochondrial complex I precede excitatory amino acid-mediated neurodegeneration
    • Sriram K., Shankar S. K., Boyd M. R., Ravindranath V. Thiol oxidation and loss of mitochondrial complex I precede excitatory amino acid-mediated neurodegeneration. J. Neurosci. 18:1998;10287-10296.
    • (1998) J. Neurosci. , vol.18 , pp. 10287-10296
    • Sriram, K.1    Shankar, S.K.2    Boyd, M.R.3    Ravindranath, V.4
  • 69
    • 0031766792 scopus 로고    scopus 로고
    • Traumatic brain injury alters synaptic homeostasis: Implications for impaired mitochondrial and transport function
    • Sullivan P. G., Keller J. N., Mattson M. P., Scheff S. W. Traumatic brain injury alters synaptic homeostasis: Implications for impaired mitochondrial and transport function. J. Neurotrauma. 15:1998;789-798.
    • (1998) J. Neurotrauma , vol.15 , pp. 789-798
    • Sullivan, P.G.1    Keller, J.N.2    Mattson, M.P.3    Scheff, S.W.4
  • 70
    • 0029796321 scopus 로고    scopus 로고
    • Effect of glutamate receptor ligands on mitochondrial membrane potential in rat dissociated cerebellar cells
    • Sureda F. X., Escubedo E., Gabriel C., Camarasa J., Camins A. Effect of glutamate receptor ligands on mitochondrial membrane potential in rat dissociated cerebellar cells. Naunyn Schmeidebergs Arch. Pharmacol. 354:1996;420-423.
    • (1996) Naunyn Schmeidebergs Arch. Pharmacol. , vol.354 , pp. 420-423
    • Sureda, F.X.1    Escubedo, E.2    Gabriel, C.3    Camarasa, J.4    Camins, A.5
  • 71
    • 0025905910 scopus 로고
    • The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A
    • Szabo I., M Zoratti. The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A. J. Biol. Chem. 266:1991;3376-3379.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3376-3379
    • Szabo, I.1    M., Z.2
  • 72
    • 0015910804 scopus 로고
    • Lipid peroxidation damage to cell components
    • Tappel A. L. Lipid peroxidation damage to cell components. Fed. Proc. 32:1973;1870-1874.
    • (1973) Fed. Proc. , vol.32 , pp. 1870-1874
    • Tappel, A.L.1
  • 73
    • 0028949380 scopus 로고
    • Glutamate-induced calcium loads: Effects on energy metabolism and neuronal viability
    • Thayer S. A., Wang G. J. Glutamate-induced calcium loads: Effects on energy metabolism and neuronal viability. Clin. Exp. Pharmacol. Physiol. 22:1995;303-304.
    • (1995) Clin. Exp. Pharmacol. Physiol. , vol.22 , pp. 303-304
    • Thayer, S.A.1    Wang, G.J.2
  • 74
    • 0032561733 scopus 로고    scopus 로고
    • Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat
    • Uchino H., Elmer E., Uchino K., Li P. A., He Q. P., Smith M. L., Siesjo B. K. Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat. Brain Res. 812:1998;216-226.
    • (1998) Brain Res. , vol.812 , pp. 216-226
    • Uchino, H.1    Elmer, E.2    Uchino, K.3    Li, P.A.4    He, Q.P.5    Smith, M.L.6    Siesjo, B.K.7
  • 75
    • 0029590050 scopus 로고
    • Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat
    • Uchino H., Elmer E., Uchino K., Lindvall O., Siesjo B. K. Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat. Acta Physiol. Scand. 155:1995;469-471.
    • (1995) Acta Physiol. Scand. , vol.155 , pp. 469-471
    • Uchino, H.1    Elmer, E.2    Uchino, K.3    Lindvall, O.4    Siesjo, B.K.5
  • 76
    • 0030915477 scopus 로고    scopus 로고
    • Mitochondrial dysfunction after experimental and human brain injury and its possible reversal with a selective N-type calcium channel antagonist (SNX-111)
    • Verweij B. H., Muizelaar J. P., Federico C. V., Peterson P. L., Xiong Y., Lee C. P. Mitochondrial dysfunction after experimental and human brain injury and its possible reversal with a selective N-type calcium channel antagonist (SNX-111). Neurol. Res. 19:1997;334-339.
    • (1997) Neurol. Res. , vol.19 , pp. 334-339
    • Verweij, B.H.1    Muizelaar, J.P.2    Federico, C.V.3    Peterson, P.L.4    Xiong, Y.5    Lee, C.P.6
  • 77
    • 0000434165 scopus 로고    scopus 로고
    • Sequestration of glutamate-induced Ca2+ loads by mitochondria in cultured rat hippocampal neurons
    • Wang G. J., Thayer S. A. Sequestration of glutamate-induced Ca2+ loads by mitochondria in cultured rat hippocampal neurons. J. Neurophysiol. 76:1996;1611-1621.
    • (1996) J. Neurophysiol. , vol.76 , pp. 1611-1621
    • Wang, G.J.1    Thayer, S.A.2
  • 78
    • 0029788243 scopus 로고    scopus 로고
    • Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
    • White R. J., Reynolds I. J. Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure. J. Neurosci. 16:1996;5688-5697.
    • (1996) J. Neurosci. , vol.16 , pp. 5688-5697
    • White, R.J.1    Reynolds, I.J.2
  • 79
    • 0031016799 scopus 로고    scopus 로고
    • Mitochondria accumulate Ca2+ following intense glutamate stimulation of cultured rat forebrain neurones
    • White R. J., Reynolds I. J. Mitochondria accumulate Ca2+ following intense glutamate stimulation of cultured rat forebrain neurones. J. Physiol. London. 498:1997;31-47.
    • (1997) J. Physiol. London , vol.498 , pp. 31-47
    • White, R.J.1    Reynolds, I.J.2
  • 80
    • 0002358665 scopus 로고
    • The separation of synaptic vesicles from nerve-ending particles ("synaptosomes")
    • Whittaker V. P., Michaelson I. A., Kirkland R. J. The separation of synaptic vesicles from nerve-ending particles ("synaptosomes"). Biochem. J. 90:1964;293-303.
    • (1964) Biochem. J. , vol.90 , pp. 293-303
    • Whittaker, V.P.1    Michaelson, I.A.2    Kirkland, R.J.3
  • 81
    • 0031038634 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury
    • Xiong Y., Gu Q., Peterson P. L., Muizelaar J. P., Lee C. P. Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J. Neurotrauma. 14:1997;23-34.
    • (1997) J. Neurotrauma , vol.14 , pp. 23-34
    • Xiong, Y.1    Gu, Q.2    Peterson, P.L.3    Muizelaar, J.P.4    Lee, C.P.5
  • 82
    • 0028090533 scopus 로고
    • The calcium content of mitochondria from brain subregions following short-term forebrain ischemia and recirculation in the rat
    • Zaidan E., Sims N. The calcium content of mitochondria from brain subregions following short-term forebrain ischemia and recirculation in the rat. J. Neurochem. 63:1994;1812-1819.
    • (1994) J. Neurochem. , vol.63 , pp. 1812-1819
    • Zaidan, E.1    Sims, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.