Monomeric IgG Is neuroprotective via enhancing microglial recycling endocytosis and TNF-α

Journal of Neuroscience

Volumn 28, Issue 47, 2008, Pages 12199-12211

  Hulse, Raymond E ^a   Swenson, Wade G ^a   Kunkler, Phillip E ^a   White, David M ^a   Kraig, Richard P ^a  

^a UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

Cytokine; Endocytosis; Hippocampus; Hormesis; Neuroinflammation; Neuroprotection; Slice cultures

Indexed keywords

E PROSTANOID RECEPTOR 2; IMMUNOGLOBULIN G; MINOCYCLINE; PROSTANOID RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOCYTOSIS; EXCITOTOXICITY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MICROGLIA; NEUROPROTECTION; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANOXIA; CELLS, CULTURED; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ECTODYSPLASINS; ENDOCYTOSIS; GLUCOSE; HIPPOCAMPUS; IMMUNOGLOBULIN G; INTERLEUKIN-1BETA; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; MICROGLIA; MINOCYCLINE; N-METHYLASPARTATE; NEUROPROTECTIVE AGENTS; NEUROTOXINS; ORGAN CULTURE TECHNIQUES; PHOSPHOPYRUVATE HYDRATASE; RAB GTP-BINDING PROTEINS; RATS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58149387068     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3856-08.2008     Document Type: Article

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