메뉴 건너뛰기




Volumn 27, Issue 3, 2010, Pages 497-507

In situ detection of inflammatory mediators in post mortem human brain tissue after traumatic injury

Author keywords

Cytokines; Human brain; Inflammation; Post mortem tissue; Traumatic brain injury

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 77950625842     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2009.1120     Document Type: Article
Times cited : (230)

References (53)
  • 2
    • 39449130825 scopus 로고    scopus 로고
    • Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: Effects of moderate hypothermia
    • Buttram, S.D.W., Wisniewski, S.R., Jackson, E.K., Adelson, P.D., Feldman, K., Bayir, H., Berger, R.P., Clark, R.S.B., and Kochanek, P.M. (2007). Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia. J. Neurotrauma 24, 1707-1717.
    • (2007) J. Neurotrauma , vol.24 , pp. 1707-1717
    • Buttram, S.D.W.1    Wisniewski, S.R.2    Jackson, E.K.3    Adelson, P.D.4    Feldman, K.5    Bayir, H.6    Berger, R.P.7    Clark, R.S.B.8    Kochanek, P.M.9
  • 3
    • 33847261481 scopus 로고    scopus 로고
    • Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration
    • Bye, N., Habgood, M.D., Callaway, J.K., Malakooti, N., Potter, A., Kossmann, T., and Morganti-Kossmann, M.C. (2007). Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration. Exp. Neurol. 204, 220-233.
    • (2007) Exp. Neurol. , vol.204 , pp. 220-233
    • Bye, N.1    Habgood, M.D.2    Callaway, J.K.3    Malakooti, N.4    Potter, A.5    Kossmann, T.6    Morganti-Kossmann, M.C.7
  • 4
    • 26844501218 scopus 로고    scopus 로고
    • Animal models of head trauma
    • Cernak, I. (2005). Animal models of head trauma. NeuroRx 2, 410-422.
    • (2005) NeuroRx , vol.2 , pp. 410-422
    • Cernak, I.1
  • 6
    • 0027945338 scopus 로고
    • Neutrophil accumulation after traumatic brain injury in rats: Comparison of weight drop and controlled cortical impact models
    • Clark, R.S., Schiding, J.K., Kaczorowski, S.L., Marion, D.W., and Kochanek, P.M. (1994). Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models. J. Neurotrauma 11, 499-506.
    • (1994) J. Neurotrauma , vol.11 , pp. 499-506
    • Clark, R.S.1    Schiding, J.K.2    Kaczorowski, S.L.3    Marion, D.W.4    Kochanek, P.M.5
  • 7
    • 2542468694 scopus 로고    scopus 로고
    • Global road safety crisis remedy sought: 1.2 million killed, 50 million injured annually
    • Cole, T.B. (2004). Global road safety crisis remedy sought: 1.2 million killed, 50 million injured annually. JAMA 291, 2531-2532.
    • (2004) JAMA , vol.291 , pp. 2531-2532
    • Cole, T.B.1
  • 8
    • 12744260011 scopus 로고    scopus 로고
    • The neuroprotective role of inflammation in nervous system injuries
    • Correale, J., and Villa, A. (2004). The neuroprotective role of inflammation in nervous system injuries. J. Neurol. 251, 1304-1316.
    • (2004) J. Neurol. , vol.251 , pp. 1304-1316
    • Correale, J.1    Villa, A.2
  • 10
    • 0032752147 scopus 로고    scopus 로고
    • IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: Relationship to IL-6, TNF-alpha, TGF-beta1 and blood-brain barrier function
    • Csuka, E., Morganti-Kossmann, M.C., Lenzlinger, P.M., Joller, H., Trentz, O., and Kossmann, T. (1999). IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: relationship to IL-6, TNF-alpha, TGF-beta1 and blood-brain barrier function. J. Neuroimmunol. 101, 211-221.
    • (1999) J. Neuroimmunol , vol.101 , pp. 211-221
    • Csuka, E.1    Morganti-Kossmann, M.C.2    Lenzlinger, P.M.3    Joller, H.4    Trentz, O.5    Kossmann, T.6
  • 12
    • 0029960060 scopus 로고    scopus 로고
    • Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS
    • Fan, L., Young, P.R., Barone, F.C., Feuerstein, G.Z., Smith, D.H., and McIntosh, T.K. (1996). Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS. Brain Res. Mol. Brain Res. 36, 287-291.
    • (1996) Brain Res. Mol. Brain Res. , vol.36 , pp. 287-291
    • Fan, L.1    Young, P.R.2    Barone, F.C.3    Feuerstein, G.Z.4    Smith, D.H.5    McIntosh, T.K.6
  • 14
    • 57349123459 scopus 로고    scopus 로고
    • Cerebral microdialysis of interleukin (IL)-1beta and IL-6: Extraction efficiency and production in the acute phase after severe traumatic brain injury in rats
    • Folkersma, H., Brevé, J.J.P., Tilders, F.J.H., Cherian, L., Robertson, C.S., and Vandertop, W.P. (2008). Cerebral microdialysis of interleukin (IL)-1beta and IL-6: extraction efficiency and production in the acute phase after severe traumatic brain injury in rats. Acta Neurochir. 150, 1277-1284.
    • (2008) Acta Neurochir , vol.150 , pp. 1277-1284
    • Folkersma, H.1    Brevé, J.J.P.2    Tilders, F.J.H.3    Cherian, L.4    Robertson, C.S.5    Vandertop, W.P.6
  • 18
    • 20044385570 scopus 로고    scopus 로고
    • A microdialysis technique for routine measurement of macromolecules in the injured human brain
    • discussion 1268-1270
    • Hillman, J., Aneman, O., Anderson, C., Sjogren, F., Saberg, C., and Mellergard, P. (2005). A microdialysis technique for routine measurement of macromolecules in the injured human brain. Neurosurgery 56, 1264-1268; discussion 1268-1270.
    • (2005) Neurosurgery , vol.56 , pp. 1264-1268
    • Hillman, J.1    Aneman, O.2    Anderson, C.3    Sjogren, F.4    Saberg, C.5    Mellergard, P.6
  • 19
    • 4644337868 scopus 로고    scopus 로고
    • In situ detection of intracerebral cytokine expression after human brain contusion
    • Holmin, S., and Hö jeberg, B. (2004). In situ detection of intracerebral cytokine expression after human brain contusion. Neurosci. Lett. 369, 108-114.
    • (2004) Neurosci. Lett. , vol.369 , pp. 108-114
    • Holmin, S.1    Höjeberg, B.2
  • 21
    • 33646083015 scopus 로고    scopus 로고
    • The effect of traumatic brain injury upon the concentration and expression of Interleukin-1 beta and Interleukin-10 in the rat
    • Kamm, K., VanderKolk, W., Lawrence, C., Jonker, M., and Davis, A.T. (2006). The effect of traumatic brain injury upon the concentration and expression of Interleukin-1 beta and Interleukin-10 in the rat. J. Trauma 60, 152-157.
    • (2006) J. Trauma , vol.60 , pp. 152-157
    • Kamm, K.1    Vanderkolk, W.2    Lawrence, C.3    Jonker, M.4    Davis, A.T.5
  • 22
    • 0033103686 scopus 로고    scopus 로고
    • Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment
    • Knoblach, S.M., Fan, L., and Faden, A.I. (1999). Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment. J. Neuroimmunol. 95, 115-125.
    • (1999) J. Neuroimmunol. , vol.95 , pp. 115-125
    • Knoblach, S.M.1    Fan, L.2    Faden, A.I.3
  • 23
    • 0029398824 scopus 로고
    • Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries
    • Kossmann, T., Hans, V.H., Imhof, H.G., Stocker, R., Grob, P., Trentz, O., and Morganti-Kossmann, C. (1995). Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries. Shock 4, 311-317.
    • (1995) Shock , vol.4 , pp. 311-317
    • Kossmann, T.1    Hans, V.H.2    Imhof, H.G.3    Stocker, R.4    Grob, P.5    Trentz, O.6    Morganti-Kossmann, C.7
  • 24
    • 0029865078 scopus 로고    scopus 로고
    • Interleukin-6 released in human cerebrospinal fluid following traumatic brain injury may trigger nerve growth factor production in astrocytes
    • Kossmann, T., Hans, V., Imhof, H.G., Trentz, O., and Morganti-Kossmann, M.C. (1996). Interleukin-6 released in human cerebrospinal fluid following traumatic brain injury may trigger nerve growth factor production in astrocytes. Brain Res. 713, 143-152.
    • (1996) Brain Res , vol.713 , pp. 143-152
    • Kossmann, T.1    Hans, V.2    Imhof, H.G.3    Trentz, O.4    Morganti-Kossmann, M.C.5
  • 25
    • 0030939399 scopus 로고    scopus 로고
    • Interleukin-8 released into the cerebrospinal fluid after brain injury is associated with blood-brain barrier dysfunction and nerve growth factor production
    • Kossmann, T., Stahel, P.F., Lenzlinger, P.M., Redl, H., Dubs, R.W., Trentz, O., Schlag, G., and Morganti-Kossmann, M.C. (1997). Interleukin-8 released into the cerebrospinal fluid after brain injury is associated with blood-brain barrier dysfunction and nerve growth factor production. J. Cereb. Blood Flow Metab. 17, 280-289.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 280-289
    • Kossmann, T.1    Stahel, P.F.2    Lenzlinger, P.M.3    Redl, H.4    Dubs, R.W.5    Trentz, O.6    Schlag, G.7    Morganti-Kossmann, M.C.8
  • 26
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas, S.M., Rothwell, N.J., and Gibson, R.M. (2006). The role of inflammation in CNS injury and disease. Br. J. Pharmacol. 147, S232-S240.
    • (2006) Br. J. Pharmacol. , vol.147
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 27
    • 46849094295 scopus 로고    scopus 로고
    • Moderate and severe traumatic brain injury in adults
    • Maas, A.I., Stocchetti, N., and Bullock, R. (2008). Moderate and severe traumatic brain injury in adults. Lancet Neurol. 7, 728-741.
    • (2008) Lancet Neurol , vol.7 , pp. 728-741
    • Maas, A.I.1    Stocchetti, N.2    Bullock, R.3
  • 29
    • 0023223416 scopus 로고
    • Ventricular fluid interleukin-1 activity in patients with head injury
    • McClain, C.J., Cohen, D., Ott, L., Dinarello, C.A., and Young, B. (1987). Ventricular fluid interleukin-1 activity in patients with head injury. J. Lab. Clin. Med. 110, 48-54.
    • (1987) J. Lab. Clin. Med. , vol.110 , pp. 48-54
    • McClain, C.J.1    Cohen, D.2    Ott, L.3    Dinarello, C.A.4    Young, B.5
  • 30
    • 0025946766 scopus 로고
    • Increased plasma and ventricular fluid interleukin-6 levels in patients with head injury
    • McClain C.J., Cohen D., Phillips R., Ott L., and Young B. (1991). Increased plasma and ventricular fluid interleukin-6 levels in patients with head injury. J. Lab. Clin. Med. 118, 225-231.
    • (1991) J. Lab. Clin. Med. , vol.118 , pp. 225-231
    • McClain, C.J.1    Cohen, D.2    Phillips, R.3    Ott, L.4    Young, B.5
  • 31
    • 41749102224 scopus 로고    scopus 로고
    • Changes in extracellular concentrations of some cytokines, chemokines, and neurotrophic factors after insertion of intracerebral microdialysis catheters in neurosurgical patients
    • discussion 157-158
    • Mellergard, P., Aneman, O., Sjogren, F., Pettersson, P., and Hillman, J. (2008). Changes in extracellular concentrations of some cytokines, chemokines, and neurotrophic factors after insertion of intracerebral microdialysis catheters in neurosurgical patients. Neurosurgery 62, 151-157; discussion 157-158.
    • (2008) Neurosurgery , vol.62 , pp. 151-157
    • Mellergard, P.1    Aneman, O.2    Sjogren, F.3    Pettersson, P.4    Hillman, J.5
  • 32
    • 0025813019 scopus 로고
    • Effects of interleukin-1 and tumor necrosis factor-alpha on astrocytes, microglia, oligodendrocytes, and glial precursors in vitro
    • Merrill, J.E. (1991). Effects of interleukin-1 and tumor necrosis factor-alpha on astrocytes, microglia, oligodendrocytes, and glial precursors in vitro. Dev. Neurosci. 13, 130-137.
    • (1991) Dev. Neurosci. , vol.13 , pp. 130-137
    • Merrill, J.E.1
  • 33
    • 0032778919 scopus 로고    scopus 로고
    • TGF-beta is elevated in the CSF of patients with severe traumatic brain injuries and parallels blood-brain barrier function
    • Morganti-Kossmann, M.C., Hans, V.H., Lenzlinger, P.M., Dubs, R., Ludwig, E., Trentz, O., and Kossmann, T. (1999). TGF-beta is elevated in the CSF of patients with severe traumatic brain injuries and parallels blood-brain barrier function. J. Neurotrauma 16, 617-628.
    • (1999) J. Neurotrauma , vol.16 , pp. 617-628
    • Morganti-Kossmann, M.C.1    Hans, V.H.2    Lenzlinger, P.M.3    Dubs, R.4    Ludwig, E.5    Trentz, O.6    Kossmann, T.7
  • 34
    • 0035462607 scopus 로고    scopus 로고
    • Role of cerebral inflammation after traumatic brain injury: A revisited concept
    • Morganti-Kossmann, M.C., Rancan, M., Otto, V.I., Stahel, P.F., and Kossmann, T. (2001). Role of cerebral inflammation after traumatic brain injury: a revisited concept. Shock 16, 165-177.
    • (2001) Shock , vol.16 , pp. 165-177
    • Morganti-Kossmann, M.C.1    Rancan, M.2    Otto, V.I.3    Stahel, P.F.4    Kossmann, T.5
  • 38
    • 0035000152 scopus 로고    scopus 로고
    • S-100 beta reflects the extent of injury and outcome, whereas neuronal specific enolase is a better indicator of neuroinflammation in patients with severe traumatic brain injury
    • Pleines, U.E., Morganti-Kossmann, M.C., Rancan, M., Joller, H., Trentz, O., and Kossmann, T. (2001). S-100 beta reflects the extent of injury and outcome, whereas neuronal specific enolase is a better indicator of neuroinflammation in patients with severe traumatic brain injury. J. Neurotrauma 18, 491-498.
    • (2001) J. Neurotrauma , vol.18 , pp. 491-498
    • Pleines, U.E.1    Morganti-Kossmann, M.C.2    Rancan, M.3    Joller, H.4    Trentz, O.5    Kossmann, T.6
  • 39
    • 0031776012 scopus 로고    scopus 로고
    • Soluble ICAM-1 in CSF coincides with the extent of cerebral damage in patients with severe traumatic brain injury
    • Pleines, U.E., Stover, J.F., Kossmann, T., Trentz, O., and Morganti-Kossmann, M.C. (1998). Soluble ICAM-1 in CSF coincides with the extent of cerebral damage in patients with severe traumatic brain injury. J. Neurotrauma 15, 399-409.
    • (1998) J. Neurotrauma , vol.15 , pp. 399-409
    • Pleines, U.E.1    Stover, J.F.2    Kossmann, T.3    Trentz, O.4    Morganti-Kossmann, M.C.5
  • 40
    • 0035282770 scopus 로고    scopus 로고
    • Upregulation of ICAM-1 and MCP-1 but not of MIP-2 and sensorimotor deficit in response to traumatic axonal injury in rats
    • Rancan, M., Otto, V.I., Hans, V.H., Gerlach, I., Jork, R., Trentz, O., Kossmann, T., and Morganti-Kossmann, M.C. (2001). Upregulation of ICAM-1 and MCP-1 but not of MIP-2 and sensorimotor deficit in response to traumatic axonal injury in rats. J. Neurosci. Res. 63, 438-446.
    • (2001) J. Neurosci. Res. , vol.63 , pp. 438-446
    • Rancan, M.1    Otto, V.I.2    Hans, V.H.3    Gerlach, I.4    Jork, R.5    Trentz, O.6    Kossmann, T.7    Morganti-Kossmann, M.C.8
  • 42
    • 0028364659 scopus 로고
    • Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue
    • Shohami, E., Novikov, M., Bass, R., Yamin, A., and Gallily, R. (1994). Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue. J. Cereb. Blood Flow Metab. 14, 615-619.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 615-619
    • Shohami, E.1    Novikov, M.2    Bass, R.3    Yamin, A.4    Gallily, R.5
  • 43
    • 17544375423 scopus 로고    scopus 로고
    • Experimental closed head injury: Analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines
    • Stahel, P.F., Shohami, E., Younis, F.M., Kariya, K., Otto, V.I., Lenzlinger, P.M., Grosjean, M.B., Eugster, H.P., Trentz, O., Kossmann, T., and Morganti-Kossmann, M.C. (2000). Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines. J. Cereb. Blood Flow Metab. 20, 369-380.
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 369-380
    • Stahel, P.F.1    Shohami, E.2    Younis, F.M.3    Kariya, K.4    Otto, V.I.5    Lenzlinger, P.M.6    Grosjean, M.B.7    Eugster, H.P.8    Trentz, O.9    Kossmann, T.10    Morganti-Kossmann, M.C.11
  • 45
    • 0027400847 scopus 로고
    • Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand
    • Taupin, V., Toulmond, S., Serrano, A., Benavides, J., and Zavala, F. (1993). Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand. J. Neuroimmunol. 42, 177-185.
    • (1993) J. Neuroimmunol. , vol.42 , pp. 177-185
    • Taupin, V.1    Toulmond, S.2    Serrano, A.3    Benavides, J.4    Zavala, F.5
  • 46
    • 34447527791 scopus 로고    scopus 로고
    • Pathophysiology of traumatic brain injury
    • Werner, C., and Engelhard, K. (2007). Pathophysiology of traumatic brain injury. Br. J. Anaesth. 99, 4-9.
    • (2007) Br. J. Anaesth. , vol.99 , pp. 4-9
    • Werner, C.1    Engelhard, K.2
  • 48
    • 1842776269 scopus 로고    scopus 로고
    • [WHO] World Health Organization. Geneva: World Health Organization
    • World Health Organization. (2004). World report on traffic injury prevention. Geneva: World Health Organization.
    • (2004) World Report on Traffic Injury Prevention
  • 49
    • 0037107017 scopus 로고    scopus 로고
    • A microdialysis method for the recovery of IL-1beta, IL-6 and nerve growth factor from human brain in vivo
    • Winter, C.D., Iannotti, F., Pringle, A.K., Trikkas, C., Clough, G.F., and Church, M.K. (2002). A microdialysis method for the recovery of IL-1beta, IL-6 and nerve growth factor from human brain in vivo. J. Neurosci. Methods 119, 45-50.
    • (2002) J. Neurosci. Methods , vol.119 , pp. 45-50
    • Winter, C.D.1    Iannotti, F.2    Pringle, A.K.3    Trikkas, C.4    Clough, G.F.5    Church, M.K.6
  • 50
    • 0742288542 scopus 로고    scopus 로고
    • Raised parenchymal interleukin-6 levels correlate with improved outcome after traumatic brain injury
    • Winter, C.D., Pringle, A.K., Clough, G.F., and Church, M.K. (2004). Raised parenchymal interleukin-6 levels correlate with improved outcome after traumatic brain injury. Brain 127, 315-320.
    • (2004) Brain , vol.127 , pp. 315-320
    • Winter, C.D.1    Pringle, A.K.2    Clough, G.F.3    Church, M.K.4
  • 51
    • 0027331911 scopus 로고
    • Tumor necrosis factor-alpha: Specific binding sites in rodent brain and pituitary gland
    • Wolvers, D.A., Marquette, C., Berkenbosch, F., and Haour, F. (1993). Tumor necrosis factor-alpha: specific binding sites in rodent brain and pituitary gland. Eur. Cytokine Netw. 4, 377-381.
    • (1993) Eur. Cytokine Netw. , vol.4 , pp. 377-381
    • Wolvers, D.A.1    Marquette, C.2    Berkenbosch, F.3    Haour, F.4
  • 52
    • 0025820808 scopus 로고
    • Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: Evidence of a role for microglia in cytokine production
    • Woodroofe, M.N., Sarna, G.S., Wadhwa, M., Hayes, G.M., Loughlin, A.J., Tinker, A., and Cuzner, M.L. (1991). Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production. J. Neuroimmunol. 33, 227-236.
    • (1991) J. Neuroimmunol. , vol.33 , pp. 227-236
    • Woodroofe, M.N.1    Sarna, G.S.2    Wadhwa, M.3    Hayes, G.M.4    Loughlin, A.J.5    Tinker, A.6    Cuzner, M.L.7
  • 53
    • 0037927979 scopus 로고    scopus 로고
    • Caspase-8 expression and proteolysis in human brain after severe head injury
    • published online May 8 2003, doi:10.1096/02- 1067fje
    • Zhang, X., Graham, S.H., Kochanek, P.M., Marion, D.W., Nathaniel, P.D., Watkins, S.C., and Clark, R.B. (2003). Caspase-8 expression and proteolysis in human brain after severe head injury. FASEB J. published online May 8, 2003, doi:10.1096/02- 1067fje.
    • (2003) FASEB J
    • Zhang, X.1    Graham, S.H.2    Kochanek, P.M.3    Marion, D.W.4    Nathaniel, P.D.5    Watkins, S.C.6    Clark, R.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.