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Volumn , Issue , 2010, Pages 705-754

The Role of Oxidative Stress in Endothelial Dysfunction and Vascular Inflammation

Author keywords

Aging; Atherosclerosis; Diabetes; Endothelial dysfunction; Inflammation; Nitric oxide; Reactive oxygen species

Indexed keywords


EID: 78049239775     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-373866-0.00022-8     Document Type: Chapter
Times cited : (12)

References (305)
  • 1
    • 0035514402 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces manganese-superoxide dismutase expression in endothelial cells by a Rac1-regulated NADPH oxidase-dependent mechanism
    • Abid M.R., Tsai J.C., Spokes K.C., Deshpande S.S., Irani K., Aird W.C. Vascular endothelial growth factor induces manganese-superoxide dismutase expression in endothelial cells by a Rac1-regulated NADPH oxidase-dependent mechanism. FASEB J 2001, 15:2548-2550.
    • (2001) FASEB J , vol.15 , pp. 2548-2550
    • Abid, M.R.1    Tsai, J.C.2    Spokes, K.C.3    Deshpande, S.S.4    Irani, K.5    Aird, W.C.6
  • 2
    • 6344231842 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB
    • Abid M.R., Schoots I.G., Spokes K.C., Wu S.Q., Mawhinney C., Aird W.C. Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB. J. Biol. Chem. 2004, 279:44030-44038.
    • (2004) J. Biol. Chem. , vol.279 , pp. 44030-44038
    • Abid, M.R.1    Schoots, I.G.2    Spokes, K.C.3    Wu, S.Q.4    Mawhinney, C.5    Aird, W.C.6
  • 10
    • 34247632152 scopus 로고    scopus 로고
    • Stem cells and the regeneration of the aging cardiovascular system
    • Ballard V.L., Edelberg J.M. Stem cells and the regeneration of the aging cardiovascular system. Circ. Res. 2007, 100:1116-1127.
    • (2007) Circ. Res. , vol.100 , pp. 1116-1127
    • Ballard, V.L.1    Edelberg, J.M.2
  • 11
    • 18044383110 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in cardiovascular disease
    • Ballinger S.W. Mitochondrial dysfunction in cardiovascular disease. Free Radic. Biol. Med. 2005, 38:1278-1295.
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 1278-1295
    • Ballinger, S.W.1
  • 15
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly
    • Beckman J.S., Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am. J. Physiol. 1996, 271:C1424-C1437.
    • (1996) Am. J. Physiol. , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 16
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide
    • Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freeman B.A. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U S A 1990, 87:1620-1624.
    • (1990) Proc. Natl. Acad. Sci. U S A , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 17
    • 0035957267 scopus 로고    scopus 로고
    • Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans
    • Beckman J.A., Goldfine A.B., Gordon M.B., Creager M.A. Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans. Circulation 2001, 103:1618-1623.
    • (2001) Circulation , vol.103 , pp. 1618-1623
    • Beckman, J.A.1    Goldfine, A.B.2    Gordon, M.B.3    Creager, M.A.4
  • 18
    • 0037092995 scopus 로고    scopus 로고
    • Diabetes and atherosclerosis: epidemiology, pathophysiology, and management
    • Beckman J.A., Creager M.A., Libby P. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. Jama 2002, 287:2570-2581.
    • (2002) Jama , vol.287 , pp. 2570-2581
    • Beckman, J.A.1    Creager, M.A.2    Libby, P.3
  • 19
    • 0037059549 scopus 로고    scopus 로고
    • Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans
    • Beckman J.A., Goldfine A.B., Gordon M.B., Garrett L.A., Creager M.A. Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans. Circ. Res. 2002, 90:107-111.
    • (2002) Circ. Res. , vol.90 , pp. 107-111
    • Beckman, J.A.1    Goldfine, A.B.2    Gordon, M.B.3    Garrett, L.A.4    Creager, M.A.5
  • 20
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
    • Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 2007, 87:245-313.
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 22
    • 1642484244 scopus 로고    scopus 로고
    • Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications
    • Berry C.E., Hare J.M. Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications. J. Physiol. 2004, 555:589-606.
    • (2004) J. Physiol. , vol.555 , pp. 589-606
    • Berry, C.E.1    Hare, J.M.2
  • 24
    • 15444379908 scopus 로고    scopus 로고
    • L-Arginine improves vascular function by overcoming deleterious effects of ADMA, a novel cardiovascular risk factor
    • Boger R.H., Ron E.S. L-Arginine improves vascular function by overcoming deleterious effects of ADMA, a novel cardiovascular risk factor. Altern. Med. Rev. 2005, 10:14-23.
    • (2005) Altern. Med. Rev. , vol.10 , pp. 14-23
    • Boger, R.H.1    Ron, E.S.2
  • 25
    • 33748942862 scopus 로고    scopus 로고
    • The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting
    • Bogoyevitch M.A. The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting. Bioessays 2006, 28:923-934.
    • (2006) Bioessays , vol.28 , pp. 923-934
    • Bogoyevitch, M.A.1
  • 26
    • 0030956584 scopus 로고    scopus 로고
    • Apoptotic vascular endothelial cells become procoagulant
    • Bombeli T., Karsan A., Tait J.F., Harlan J.M. Apoptotic vascular endothelial cells become procoagulant. Blood 1997, 89:2429-2442.
    • (1997) Blood , vol.89 , pp. 2429-2442
    • Bombeli, T.1    Karsan, A.2    Tait, J.F.3    Harlan, J.M.4
  • 29
    • 1542408721 scopus 로고    scopus 로고
    • The diabetes epidemic: a national and global crisis
    • Bonow R.O., Gheorghiade M. The diabetes epidemic: a national and global crisis. Am. J. Med. 2004, 116(Suppl 5A):2S-10S.
    • (2004) Am. J. Med. , vol.116 , Issue.SUPPL.5A
    • Bonow, R.O.1    Gheorghiade, M.2
  • 30
    • 0037167664 scopus 로고    scopus 로고
    • World Heart Day 2002: the international burden of cardiovascular disease: responding to the emerging global epidemic
    • Bonow R.O., Smaha L.A., Smith S.C., Mensah G.A., Lenfant C. World Heart Day 2002: the international burden of cardiovascular disease: responding to the emerging global epidemic. Circulation 2002, 106:1602-1605.
    • (2002) Circulation , vol.106 , pp. 1602-1605
    • Bonow, R.O.1    Smaha, L.A.2    Smith, S.C.3    Mensah, G.A.4    Lenfant, C.5
  • 33
    • 0034065857 scopus 로고    scopus 로고
    • Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension
    • Butler R., Morris A.D., Belch J.J., Hill A., Struthers A.D. Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension. Hypertension 2000, 35:746-751.
    • (2000) Hypertension , vol.35 , pp. 746-751
    • Butler, R.1    Morris, A.D.2    Belch, J.J.3    Hill, A.4    Struthers, A.D.5
  • 34
    • 0029895815 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite
    • Buttery L.D., Springall D.R., Chester A.H., Evans T.J., Standfield E.N., Parums D.V., Yacoub M.H., Polak J.M. Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite. Lab Invest. 1996, 75:77-85.
    • (1996) Lab Invest. , vol.75 , pp. 77-85
    • Buttery, L.D.1    Springall, D.R.2    Chester, A.H.3    Evans, T.J.4    Standfield, E.N.5    Parums, D.V.6    Yacoub, M.H.7    Polak, J.M.8
  • 35
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress
    • Cai H., Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 2000, 87:840-844.
    • (2000) Circ. Res. , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 37
    • 0030750723 scopus 로고    scopus 로고
    • Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients
    • Cardillo C., Kilcoyne C.M., Cannon R.O., Quyyumi A.A., Panza J.A. Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients. Hypertension 1997, 30:57-63.
    • (1997) Hypertension , vol.30 , pp. 57-63
    • Cardillo, C.1    Kilcoyne, C.M.2    Cannon, R.O.3    Quyyumi, A.A.4    Panza, J.A.5
  • 38
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • Carmeliet P. Angiogenesis in health and disease. Nat. Med. 2003, 9:653-660.
    • (2003) Nat. Med. , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 41
    • 0027368884 scopus 로고
    • Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats
    • Chen P.Y., Sanders P.W. Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats. Hypertension 1993, 22:812-818.
    • (1993) Hypertension , vol.22 , pp. 812-818
    • Chen, P.Y.1    Sanders, P.W.2
  • 43
    • 0033986606 scopus 로고    scopus 로고
    • Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: role of cationic amino acid transporters
    • Closs E.I., Scheld J.S., Sharafi M., Forstermann U. Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: role of cationic amino acid transporters. Mol. Pharmacol. 2000, 57:68-74.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 68-74
    • Closs, E.I.1    Scheld, J.S.2    Sharafi, M.3    Forstermann, U.4
  • 44
    • 0034746311 scopus 로고    scopus 로고
    • NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?
    • Collins T., Cybulsky M.I. NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?. J. Clin. Invest. 2001, 107:255-264.
    • (2001) J. Clin. Invest. , vol.107 , pp. 255-264
    • Collins, T.1    Cybulsky, M.I.2
  • 45
    • 1942438521 scopus 로고    scopus 로고
    • Asymmetrical dimethylarginine: the Uber marker?
    • Cooke J.P. Asymmetrical dimethylarginine: the Uber marker?. Circulation 2004, 109:1813-1818.
    • (2004) Circulation , vol.109 , pp. 1813-1818
    • Cooke, J.P.1
  • 47
    • 0028813306 scopus 로고
    • Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries
    • Cosentino F., Katusic Z.S. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries. Circulation 1995, 91:139-144.
    • (1995) Circulation , vol.91 , pp. 139-144
    • Cosentino, F.1    Katusic, Z.S.2
  • 48
    • 0029569090 scopus 로고
    • Maintenance of vascular integrity: role of nitric oxide and other bradykinin mediators
    • Cosentino F., Luscher T.F. Maintenance of vascular integrity: role of nitric oxide and other bradykinin mediators. Eur. Heart J 1995, 16(Suppl K):4-12.
    • (1995) Eur. Heart J , vol.16 , Issue.SUPPL.K , pp. 4-12
    • Cosentino, F.1    Luscher, T.F.2
  • 49
    • 0031874893 scopus 로고    scopus 로고
    • Tetrahydrobiopterin and endothelial function
    • Cosentino F., Luscher T.F. Tetrahydrobiopterin and endothelial function. Eur. Heart J. 1998, 19(Suppl G):G3-G8.
    • (1998) Eur. Heart J. , vol.19 , Issue.SUPPL.G
    • Cosentino, F.1    Luscher, T.F.2
  • 50
    • 0030837996 scopus 로고    scopus 로고
    • High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
    • Cosentino F., Hishikawa K., Katusic Z.S., Luscher T.F. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 1997, 96:25-28.
    • (1997) Circulation , vol.96 , pp. 25-28
    • Cosentino, F.1    Hishikawa, K.2    Katusic, Z.S.3    Luscher, T.F.4
  • 53
    • 0141615827 scopus 로고    scopus 로고
    • Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I
    • Creager M.A., Luscher T.F., Cosentino F., Beckman J.A. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I. Circulation 2003, 108:1527-1532.
    • (2003) Circulation , vol.108 , pp. 1527-1532
    • Creager, M.A.1    Luscher, T.F.2    Cosentino, F.3    Beckman, J.A.4
  • 54
  • 55
    • 33847032609 scopus 로고    scopus 로고
    • Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging
    • Csiszar A., Labinskyy N., Smith K., Rivera A., Orosz Z., Ungvari Z. Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. Am. J Pathol. 2007, 170:388-398.
    • (2007) Am. J Pathol. , vol.170 , pp. 388-398
    • Csiszar, A.1    Labinskyy, N.2    Smith, K.3    Rivera, A.4    Orosz, Z.5    Ungvari, Z.6
  • 56
    • 54049150794 scopus 로고    scopus 로고
    • Pulsatile stretch induces release of angiotensin II and oxidative stress in human endothelial cells: effects of ACE inhibition and AT1 receptor antagonism
    • Delli Gatti C., Osto E., Kouroedov A., Eto M., Shaw S., Volpe M., Luscher T.F., Cosentino F. Pulsatile stretch induces release of angiotensin II and oxidative stress in human endothelial cells: effects of ACE inhibition and AT1 receptor antagonism. Clin. Exp. Hypertens 2008, 30:616-627.
    • (2008) Clin. Exp. Hypertens , vol.30 , pp. 616-627
    • Delli Gatti, C.1    Osto, E.2    Kouroedov, A.3    Eto, M.4    Shaw, S.5    Volpe, M.6    Luscher, T.F.7    Cosentino, F.8
  • 57
    • 0026338964 scopus 로고
    • Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine
    • Drexler H., Zeiher A.M., Meinzer K., Just H. Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine. Lancet 1991, 338:1546-1550.
    • (1991) Lancet , vol.338 , pp. 1546-1550
    • Drexler, H.1    Zeiher, A.M.2    Meinzer, K.3    Just, H.4
  • 58
    • 0033952940 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide
    • Drummond G.R., Cai H., Davis M.E., Ramasamy S., Harrison D.G. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide. Circ. Res. 2000, 86:347-354.
    • (2000) Circ. Res. , vol.86 , pp. 347-354
    • Drummond, G.R.1    Cai, H.2    Davis, M.E.3    Ramasamy, S.4    Harrison, D.G.5
  • 59
    • 0033525860 scopus 로고    scopus 로고
    • Carboxyl-terminal phosphorylation regulates the function and subcellular localization of protein kinase C betaII
    • Edwards A.S., Faux M.C., Scott J.D., Newton A.C. Carboxyl-terminal phosphorylation regulates the function and subcellular localization of protein kinase C betaII. J. Biol. Chem. 1999, 274:6461-6468.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6461-6468
    • Edwards, A.S.1    Faux, M.C.2    Scott, J.D.3    Newton, A.C.4
  • 60
    • 0013926855 scopus 로고
    • Metabolic studies of allopurinol, an inhibitor of xanthine oxidase
    • Elion G.B., Kovensky A., Hitchings G.H. Metabolic studies of allopurinol, an inhibitor of xanthine oxidase. Biochem. Pharmacol. 1966, 15:863-880.
    • (1966) Biochem. Pharmacol. , vol.15 , pp. 863-880
    • Elion, G.B.1    Kovensky, A.2    Hitchings, G.H.3
  • 62
    • 0034630917 scopus 로고    scopus 로고
    • Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey
    • Fang J., Alderman M.H. Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. JAMA 2000, 283:2404-2410.
    • (2000) JAMA , vol.283 , pp. 2404-2410
    • Fang, J.1    Alderman, M.H.2
  • 63
    • 0029876139 scopus 로고    scopus 로고
    • Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death
    • Farb A., Burke A.P., Tang A.L., Liang T.Y., Mannan P., Smialek J., Virmani R. Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death. Circulation 1996, 93:1354-1363.
    • (1996) Circulation , vol.93 , pp. 1354-1363
    • Farb, A.1    Burke, A.P.2    Tang, A.L.3    Liang, T.Y.4    Mannan, P.5    Smialek, J.6    Virmani, R.7
  • 65
    • 33748421398 scopus 로고    scopus 로고
    • Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture)
    • Feletou M., Vanhoutte P.M. Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H985-H1002.
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.291
    • Feletou, M.1    Vanhoutte, P.M.2
  • 66
    • 0034123963 scopus 로고    scopus 로고
    • Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma
    • Feng J., Han J., Pearce S.F., Silverstein R.L., Gotto A.M., Hajjar D.P., Nicholson A.C. Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma. J. Lipid Res. 2000, 41:688-696.
    • (2000) J. Lipid Res. , vol.41 , pp. 688-696
    • Feng, J.1    Han, J.2    Pearce, S.F.3    Silverstein, R.L.4    Gotto, A.M.5    Hajjar, D.P.6    Nicholson, A.C.7
  • 67
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T., Holbrook N.J. Oxidants, oxidative stress and the biology of ageing. Nature 2000, 408:239-247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 69
    • 0025055321 scopus 로고
    • Prevalence and prognostic significance of exercise-induced silent myocardial ischemia detected by thallium scintigraphy and electrocardiography in asymptomatic volunteers
    • Fleg J.L., Gerstenblith G., Zonderman A.B., Becker L.C., Weisfeldt M.L., Costa P.T., Lakatta E.G. Prevalence and prognostic significance of exercise-induced silent myocardial ischemia detected by thallium scintigraphy and electrocardiography in asymptomatic volunteers. Circulation 1990, 81:428-436.
    • (1990) Circulation , vol.81 , pp. 428-436
    • Fleg, J.L.1    Gerstenblith, G.2    Zonderman, A.B.3    Becker, L.C.4    Weisfeldt, M.L.5    Costa, P.T.6    Lakatta, E.G.7
  • 70
    • 3242712276 scopus 로고    scopus 로고
    • Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers
    • Forman H.J., Fukuto J.M., Torres M. Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers. Am. J. Physiol. Cell Physiol. 2004, 287:C246-C256.
    • (2004) Am. J. Physiol. Cell Physiol. , vol.287
    • Forman, H.J.1    Fukuto, J.M.2    Torres, M.3
  • 71
    • 33645780634 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase in vascular disease: from marvel to menace
    • Forstermann U., Munzel T. Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation 2006, 113:1708-1714.
    • (2006) Circulation , vol.113 , pp. 1708-1714
    • Forstermann, U.1    Munzel, T.2
  • 73
    • 0032514666 scopus 로고    scopus 로고
    • Impaired platelet production of nitric oxide predicts presence of acute coronary syndromes
    • Freedman J.E., Ting B., Hankin B., Loscalzo J., Keaney J.F., Vita J.A. Impaired platelet production of nitric oxide predicts presence of acute coronary syndromes. Circulation 1998, 98:1481-1486.
    • (1998) Circulation , vol.98 , pp. 1481-1486
    • Freedman, J.E.1    Ting, B.2    Hankin, B.3    Loscalzo, J.4    Keaney, J.F.5    Vita, J.A.6
  • 74
    • 0036182797 scopus 로고    scopus 로고
    • Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia
    • Fukuda Y., Teragawa H., Matsuda K., Yamagata T., Matsuura H., Chayama K. Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia. Heart 2002, 87:264-269.
    • (2002) Heart , vol.87 , pp. 264-269
    • Fukuda, Y.1    Teragawa, H.2    Matsuda, K.3    Yamagata, T.4    Matsuura, H.5    Chayama, K.6
  • 76
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott R.F., Zawadzki J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980, 288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 77
    • 0242286648 scopus 로고    scopus 로고
    • Testing endothelial vasomotor function: nitric oxide, a multipotent molecule
    • Ganz P., Vita J.A. Testing endothelial vasomotor function: nitric oxide, a multipotent molecule. Circulation 2003, 108:2049-2053.
    • (2003) Circulation , vol.108 , pp. 2049-2053
    • Ganz, P.1    Vita, J.A.2
  • 78
    • 0030028147 scopus 로고    scopus 로고
    • Molecular therapies for vascular diseases
    • Gibbons G.H., Dzau V.J. Molecular therapies for vascular diseases. Science 1996, 272:689-693.
    • (1996) Science , vol.272 , pp. 689-693
    • Gibbons, G.H.1    Dzau, V.J.2
  • 82
    • 0348110529 scopus 로고    scopus 로고
    • Endothelial function, inflammation, and prognosis in cardiovascular disease
    • Gonzalez M.A., Selwyn A.P. Endothelial function, inflammation, and prognosis in cardiovascular disease. Am. J. Med. 2003, 115(Suppl 8A):99S-106S.
    • (2003) Am. J. Med. , vol.115 , Issue.SUPPL.8A
    • Gonzalez, M.A.1    Selwyn, A.P.2
  • 83
    • 0035806914 scopus 로고    scopus 로고
    • Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study
    • Gori T., Burstein J.M., Ahmed S., Miner S.E., Al-Hesayen A., Kelly S., Parker J.D. Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study. Circulation 2001, 104:1119-1123.
    • (2001) Circulation , vol.104 , pp. 1119-1123
    • Gori, T.1    Burstein, J.M.2    Ahmed, S.3    Miner, S.E.4    Al-Hesayen, A.5    Kelly, S.6    Parker, J.D.7
  • 84
    • 4744338284 scopus 로고    scopus 로고
    • Arginine and endothelial and vascular health
    • discussion 2895S
    • Gornik H.L., Creager M.A. Arginine and endothelial and vascular health. J. Nutr. 2004, 134:2880S-2887S. discussion 2895S.
    • (2004) J. Nutr. , vol.134
    • Gornik, H.L.1    Creager, M.A.2
  • 85
    • 1942468123 scopus 로고    scopus 로고
    • Novel NAD(P)H oxidases in the cardiovascular system
    • Griendling K.K. Novel NAD(P)H oxidases in the cardiovascular system. Heart 2004, 90:491-493.
    • (2004) Heart , vol.90 , pp. 491-493
    • Griendling, K.K.1
  • 86
    • 33750923115 scopus 로고    scopus 로고
    • NADPH oxidases: new regulators of old functions
    • Griendling K.K. NADPH oxidases: new regulators of old functions. Antioxid Redox Signal 2006, 8:1443-1445.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1443-1445
    • Griendling, K.K.1
  • 87
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling K.K., Minieri C.A., Ollerenshaw J.D., Alexander R.W. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ. Res. 1994, 74:1141-1148.
    • (1994) Circ. Res. , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 88
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: role in cardiovascular biology and disease
    • Griendling K.K., Sorescu D., Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ. Res. 2000, 86:494-501.
    • (2000) Circ. Res. , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 89
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice
    • Gu L., Okada Y., Clinton S.K., Gerard C., Sukhova G.K., Libby P., Rollins B.J. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol. Cell 1998, 2:275-281.
    • (1998) Mol. Cell , vol.2 , pp. 275-281
    • Gu, L.1    Okada, Y.2    Clinton, S.K.3    Gerard, C.4    Sukhova, G.K.5    Libby, P.6    Rollins, B.J.7
  • 90
    • 33646525680 scopus 로고    scopus 로고
    • Vascular NADPH oxidases as drug targets for novel antioxidant strategies
    • Guzik T.J., Harrison D.G. Vascular NADPH oxidases as drug targets for novel antioxidant strategies. Drug Discov Today 2006, 11:524-533.
    • (2006) Drug Discov Today , vol.11 , pp. 524-533
    • Guzik, T.J.1    Harrison, D.G.2
  • 91
    • 0034640107 scopus 로고    scopus 로고
    • Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors
    • Guzik T.J., West N.E., Black E., McDonald D., Ratnatunga C., Pillai R., Channon K.M. Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors. Circ. Res. 2000, 86:E85-E90.
    • (2000) Circ. Res. , vol.86
    • Guzik, T.J.1    West, N.E.2    Black, E.3    McDonald, D.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 92
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • Guzik T.J., Mussa S., Gastaldi D., Sadowski J., Ratnatunga C., Pillai R., Channon K.M. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 2002, 105:1656-1662.
    • (2002) Circulation , vol.105 , pp. 1656-1662
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3    Sadowski, J.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 96
    • 0024564340 scopus 로고
    • Plasma amino acids in relation to metabolic control in insulin-dependent diabetic children
    • Hagenfeldt L., Dahlquist G., Persson B. Plasma amino acids in relation to metabolic control in insulin-dependent diabetic children. Acta Paediatr. Scand. 1989, 78:278-282.
    • (1989) Acta Paediatr. Scand. , vol.78 , pp. 278-282
    • Hagenfeldt, L.1    Dahlquist, G.2    Persson, B.3
  • 97
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 2005, 352:1685-1695.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 98
    • 0031897103 scopus 로고    scopus 로고
    • Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994
    • Harris M.I., Flegal K.M., Cowie C.C., Eberhardt M.S., Goldstein D.E., Little R.R., Wiedmeyer H.M., Byrd-Holt D.D. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care 1998, 21:518-524.
    • (1998) Diabetes Care , vol.21 , pp. 518-524
    • Harris, M.I.1    Flegal, K.M.2    Cowie, C.C.3    Eberhardt, M.S.4    Goldstein, D.E.5    Little, R.R.6    Wiedmeyer, H.M.7    Byrd-Holt, D.D.8
  • 99
    • 4744365177 scopus 로고    scopus 로고
    • Ischemia-reperfusion selectively impairs nitric oxide-mediated dilation in coronary arterioles: counteracting role of arginase
    • Hein T.W., Zhang C., Wang W., Chang C.I., Thengchaisri N., Kuo L. Ischemia-reperfusion selectively impairs nitric oxide-mediated dilation in coronary arterioles: counteracting role of arginase. FASEB J 2003, 17:2328-2330.
    • (2003) FASEB J , vol.17 , pp. 2328-2330
    • Hein, T.W.1    Zhang, C.2    Wang, W.3    Chang, C.I.4    Thengchaisri, N.5    Kuo, L.6
  • 100
    • 0028214851 scopus 로고
    • Sick vessel syndrome. Can atherosclerotic arteries recover?
    • Heistad D.D., Armstrong M.L. Sick vessel syndrome. Can atherosclerotic arteries recover?. Circulation 1994, 89:2447-2450.
    • (1994) Circulation , vol.89 , pp. 2447-2450
    • Heistad, D.D.1    Armstrong, M.L.2
  • 101
    • 0034602878 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: evidence for a dysfunctional nitric oxide synthase
    • Heitzer T., Brockhoff C., Mayer B., Warnholtz A., Mollnau H., Henne S., Meinertz T., Munzel T. Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: evidence for a dysfunctional nitric oxide synthase. Circ. Res. 2000, 86:E36-E41.
    • (2000) Circ. Res. , vol.86
    • Heitzer, T.1    Brockhoff, C.2    Mayer, B.3    Warnholtz, A.4    Mollnau, H.5    Henne, S.6    Meinertz, T.7    Munzel, T.8
  • 102
    • 0033752910 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus
    • Heitzer T., Krohn K., Albers S., Meinertz T. Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus. Diabetologia 2000, 43:1435-1438.
    • (2000) Diabetologia , vol.43 , pp. 1435-1438
    • Heitzer, T.1    Krohn, K.2    Albers, S.3    Meinertz, T.4
  • 103
    • 26444515018 scopus 로고    scopus 로고
    • Therapeutic potential of nitric oxide donors in the prevention and treatment of atherosclerosis
    • Herman A.G., Moncada S. Therapeutic potential of nitric oxide donors in the prevention and treatment of atherosclerosis. Eur. Heart J 2005, 26:1945-1955.
    • (2005) Eur. Heart J , vol.26 , pp. 1945-1955
    • Herman, A.G.1    Moncada, S.2
  • 104
    • 0036100972 scopus 로고    scopus 로고
    • Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals
    • Higashi Y., Sasaki S., Nakagawa K., Fukuda Y., Matsuura H., Oshima T., Chayama K. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals. Am. J. Hypertens 2002, 15:326-332.
    • (2002) Am. J. Hypertens , vol.15 , pp. 326-332
    • Higashi, Y.1    Sasaki, S.2    Nakagawa, K.3    Fukuda, Y.4    Matsuura, H.5    Oshima, T.6    Chayama, K.7
  • 107
    • 27844593740 scopus 로고    scopus 로고
    • High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway
    • Ho F.M., Lin W.W., Chen B.C., Chao C.M., Yang C.R., Lin L.Y., Lai C.C., Liu S.H., Liau C.S. High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cell Signal 2006, 18:391-399.
    • (2006) Cell Signal , vol.18 , pp. 391-399
    • Ho, F.M.1    Lin, W.W.2    Chen, B.C.3    Chao, C.M.4    Yang, C.R.5    Lin, L.Y.6    Lai, C.C.7    Liu, S.H.8    Liau, C.S.9
  • 108
    • 10344242925 scopus 로고    scopus 로고
    • Kinase signaling cascades in the mitochondrion: a matter of life or death
    • Horbinski C., Chu C.T. Kinase signaling cascades in the mitochondrion: a matter of life or death. Free Radic. Biol. Med. 2005, 38:2-11.
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 2-11
    • Horbinski, C.1    Chu, C.T.2
  • 109
    • 0033231020 scopus 로고    scopus 로고
    • From receptors to stress-activated MAP kinases
    • Ichijo H. From receptors to stress-activated MAP kinases. Oncogene 1999, 18:6087-6093.
    • (1999) Oncogene , vol.18 , pp. 6087-6093
    • Ichijo, H.1
  • 111
    • 0034852862 scopus 로고    scopus 로고
    • Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes
    • Idris I., Gray S., Donnelly R. Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. Diabetologia 2001, 44:659-673.
    • (2001) Diabetologia , vol.44 , pp. 659-673
    • Idris, I.1    Gray, S.2    Donnelly, R.3
  • 112
    • 0023518452 scopus 로고
    • Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical
    • Ignarro L.J., Byrns R.E., Buga G.M., Wood K.S. Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. Circ. Res. 1987, 61:866-879.
    • (1987) Circ. Res. , vol.61 , pp. 866-879
    • Ignarro, L.J.1    Byrns, R.E.2    Buga, G.M.3    Wood, K.S.4
  • 114
    • 0026489335 scopus 로고
    • Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation
    • Inoguchi T., Battan R., Handler E., Sportsman J.R., Heath W., King G.L. Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation. Proc. Natl. Acad. Sci. U S A 1992, 89:11059-11063.
    • (1992) Proc. Natl. Acad. Sci. U S A , vol.89 , pp. 11059-11063
    • Inoguchi, T.1    Battan, R.2    Handler, E.3    Sportsman, J.R.4    Heath, W.5    King, G.L.6
  • 115
    • 0028824312 scopus 로고
    • Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element
    • Inoue H., Yokoyama C., Hara S., Tone Y., Tanabe T. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J. Biol. Chem. 1995, 270:24965-24971.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24965-24971
    • Inoue, H.1    Yokoyama, C.2    Hara, S.3    Tone, Y.4    Tanabe, T.5
  • 116
    • 0029039754 scopus 로고
    • Peroxynitrite-mediated oxidative protein modifications
    • Ischiropoulos H., al-Mehdi A.B. Peroxynitrite-mediated oxidative protein modifications. FEBS Lett. 1995, 364:279-282.
    • (1995) FEBS Lett. , vol.364 , pp. 279-282
    • Ischiropoulos, H.1    al-Mehdi, A.B.2
  • 121
    • 72949132104 scopus 로고
    • Factors of risk in the development of coronary heart disease--six year follow-up experience. The Framingham Study
    • Kannel W.B., Dawber T.R., Kagan A., Revotskie N., Stokes J. Factors of risk in the development of coronary heart disease--six year follow-up experience. The Framingham Study. Ann. Intern. Med. 1961, 55:33-50.
    • (1961) Ann. Intern. Med. , vol.55 , pp. 33-50
    • Kannel, W.B.1    Dawber, T.R.2    Kagan, A.3    Revotskie, N.4    Stokes, J.5
  • 122
    • 58149138838 scopus 로고    scopus 로고
    • Vascular protection by tetrahydrobiopterin: progress and therapeutic prospects
    • Katusic Z.S., d'Uscio L.V., Nath K.A. Vascular protection by tetrahydrobiopterin: progress and therapeutic prospects. Trends Pharmacol. Sci. 2009, 30:48-54.
    • (2009) Trends Pharmacol. Sci. , vol.30 , pp. 48-54
    • Katusic, Z.S.1    d'Uscio, L.V.2    Nath, K.A.3
  • 124
    • 0033021938 scopus 로고    scopus 로고
    • Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium
    • Kerr S., Brosnan M.J., McIntyre M., Reid J.L., Dominiczak A.F., Hamilton C.A. Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension 1999, 33:1353-1358.
    • (1999) Hypertension , vol.33 , pp. 1353-1358
    • Kerr, S.1    Brosnan, M.J.2    McIntyre, M.3    Reid, J.L.4    Dominiczak, A.F.5    Hamilton, C.A.6
  • 125
    • 0029847340 scopus 로고    scopus 로고
    • The role of hyperglycaemia and hyperinsulinaemia in causing vascular dysfunction in diabetes
    • King G.L. The role of hyperglycaemia and hyperinsulinaemia in causing vascular dysfunction in diabetes. Ann. Med. 1996, 28:427-432.
    • (1996) Ann. Med. , vol.28 , pp. 427-432
    • King, G.L.1
  • 126
    • 0031752685 scopus 로고    scopus 로고
    • Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections
    • King H., Aubert R.E., Herman W.H. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998, 21:1414-1431.
    • (1998) Diabetes Care , vol.21 , pp. 1414-1431
    • King, H.1    Aubert, R.E.2    Herman, W.H.3
  • 127
    • 0034926855 scopus 로고    scopus 로고
    • Endothelial function and coronary artery disease
    • Kinlay S., Libby P., Ganz P. Endothelial function and coronary artery disease. Curr. Opin. Lipidol. 2001, 12:383-389.
    • (2001) Curr. Opin. Lipidol. , vol.12 , pp. 383-389
    • Kinlay, S.1    Libby, P.2    Ganz, P.3
  • 130
    • 0141706708 scopus 로고    scopus 로고
    • Class A scavenger receptor-mediated adhesion and internalization require distinct cytoplasmic domains
    • Kosswig N., Rice S., Daugherty A., Post S.R. Class A scavenger receptor-mediated adhesion and internalization require distinct cytoplasmic domains. J. Biol. Chem. 2003, 278:34219-34225.
    • (2003) J. Biol. Chem. , vol.278 , pp. 34219-34225
    • Kosswig, N.1    Rice, S.2    Daugherty, A.3    Post, S.R.4
  • 131
    • 3042736838 scopus 로고    scopus 로고
    • Selective inhibition of protein kinase Cbeta2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells
    • Kouroedov A., Eto M., Joch H., Volpe M., Luscher T.F., Cosentino F. Selective inhibition of protein kinase Cbeta2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 2004, 110:91-96.
    • (2004) Circulation , vol.110 , pp. 91-96
    • Kouroedov, A.1    Eto, M.2    Joch, H.3    Volpe, M.4    Luscher, T.F.5    Cosentino, F.6
  • 132
    • 0036775845 scopus 로고    scopus 로고
    • Sequestration of aggregated low-density lipoproteins by macrophages
    • Kruth H.S. Sequestration of aggregated low-density lipoproteins by macrophages. Curr. Opin. Lipidol. 2002, 13:483-488.
    • (2002) Curr. Opin. Lipidol. , vol.13 , pp. 483-488
    • Kruth, H.S.1
  • 133
    • 0025731835 scopus 로고
    • Nitric oxide: an endogenous modulator of leukocyte adhesion
    • Kubes P., Suzuki M., Granger D.N. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. U S A 1991, 88:4651-4655.
    • (1991) Proc. Natl. Acad. Sci. U S A , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 135
    • 0038604446 scopus 로고    scopus 로고
    • Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase
    • Kuzkaya N., Weissmann N., Harrison D.G., Dikalov S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase. J. Biol. Chem. 2003, 278:22546-22554.
    • (2003) J. Biol. Chem. , vol.278 , pp. 22546-22554
    • Kuzkaya, N.1    Weissmann, N.2    Harrison, D.G.3    Dikalov, S.4
  • 137
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis J.M., Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 2001, 81:807-869.
    • (2001) Physiol. Rev. , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 138
    • 0037469206 scopus 로고    scopus 로고
    • Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging
    • Lakatta E.G. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging. Circulation 2003, 107:490-497.
    • (2003) Circulation , vol.107 , pp. 490-497
    • Lakatta, E.G.1
  • 139
    • 0037422592 scopus 로고    scopus 로고
    • Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease
    • Lakatta E.G., Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation 2003, 107:139-146.
    • (2003) Circulation , vol.107 , pp. 139-146
    • Lakatta, E.G.1    Levy, D.2
  • 140
    • 0037458070 scopus 로고    scopus 로고
    • Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease
    • Lakatta E.G., Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease. Circulation 2003, 107:346-354.
    • (2003) Circulation , vol.107 , pp. 346-354
    • Lakatta, E.G.1    Levy, D.2
  • 143
    • 2642556244 scopus 로고    scopus 로고
    • Endothelial function: a critical determinant in atherosclerosis?
    • Landmesser U., Hornig B., Drexler H. Endothelial function: a critical determinant in atherosclerosis?. Circulation 2004, 109:II27-II33.
    • (2004) Circulation , vol.109
    • Landmesser, U.1    Hornig, B.2    Drexler, H.3
  • 145
    • 0035814951 scopus 로고    scopus 로고
    • Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin
    • Laursen J.B., Somers M., Kurz S., McCann L., Warnholtz A., Freeman B.A., Tarpey M., Fukai T., Harrison D.G. Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation 2001, 103:1282-1288.
    • (2001) Circulation , vol.103 , pp. 1282-1288
    • Laursen, J.B.1    Somers, M.2    Kurz, S.3    McCann, L.4    Warnholtz, A.5    Freeman, B.A.6    Tarpey, M.7    Fukai, T.8    Harrison, D.G.9
  • 146
    • 0000358508 scopus 로고
    • Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications
    • Lee T.S., Saltsman K.A., Ohashi H., King G.L. Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications. Proc. Natl. Acad. Sci. U S A 1989, 86:5141-5145.
    • (1989) Proc. Natl. Acad. Sci. U S A , vol.86 , pp. 5141-5145
    • Lee, T.S.1    Saltsman, K.A.2    Ohashi, H.3    King, G.L.4
  • 148
    • 0031027504 scopus 로고    scopus 로고
    • Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats
    • Lefer D.J., Scalia R., Campbell B., Nossuli T., Hayward R., Salamon M., Grayson J., Lefer A.M. Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats. J. Clin. Invest 1997, 99:684-691.
    • (1997) J. Clin. Invest , vol.99 , pp. 684-691
    • Lefer, D.J.1    Scalia, R.2    Campbell, B.3    Nossuli, T.4    Hayward, R.5    Salamon, M.6    Grayson, J.7    Lefer, A.M.8
  • 150
    • 12844253061 scopus 로고    scopus 로고
    • Endothelial function: cardiac events
    • Lerman A., Zeiher A.M. Endothelial function: cardiac events. Circulation 2005, 111:363-368.
    • (2005) Circulation , vol.111 , pp. 363-368
    • Lerman, A.1    Zeiher, A.M.2
  • 151
    • 0036081177 scopus 로고    scopus 로고
    • Atherosclerotic lesions grow through recruitment and proliferation of circulating monocytes in a murine model
    • Lessner S.M., Prado H.L., Waller E.K., Galis Z.S. Atherosclerotic lesions grow through recruitment and proliferation of circulating monocytes in a murine model. Am. J. Pathol. 2002, 160:2145-2155.
    • (2002) Am. J. Pathol. , vol.160 , pp. 2145-2155
    • Lessner, S.M.1    Prado, H.L.2    Waller, E.K.3    Galis, Z.S.4
  • 152
    • 0036852744 scopus 로고    scopus 로고
    • The macrophage foam cell as a target for therapeutic intervention
    • Li A.C., Glass C.K. The macrophage foam cell as a target for therapeutic intervention. Nat. Med. 2002, 8:1235-1242.
    • (2002) Nat. Med. , vol.8 , pp. 1235-1242
    • Li, A.C.1    Glass, C.K.2
  • 153
    • 6344285417 scopus 로고    scopus 로고
    • Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology
    • Li J.M., Shah A.M. Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2004, 287:R1014-R1030.
    • (2004) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.287
    • Li, J.M.1    Shah, A.M.2
  • 154
    • 0027476229 scopus 로고
    • An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium
    • Li H., Cybulsky M.I., Gimbrone M.A., Libby P. An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler Thromb. 1993, 13:197-204.
    • (1993) Arterioscler Thromb. , vol.13 , pp. 197-204
    • Li, H.1    Cybulsky, M.I.2    Gimbrone, M.A.3    Libby, P.4
  • 156
    • 0036430356 scopus 로고    scopus 로고
    • Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs
    • Li H., Wallerath T., Munzel T., Forstermann U. Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs. Nitric Oxide 2002, 7:149-164.
    • (2002) Nitric Oxide , vol.7 , pp. 149-164
    • Li, H.1    Wallerath, T.2    Munzel, T.3    Forstermann, U.4
  • 157
    • 1842830425 scopus 로고    scopus 로고
    • Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation
    • Li L., Sawamura T., Renier G. Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation. Circ. Res. 2004, 94:892-901.
    • (2004) Circ. Res. , vol.94 , pp. 892-901
    • Li, L.1    Sawamura, T.2    Renier, G.3
  • 158
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002, 420:868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 159
    • 0028202119 scopus 로고
    • Peroxynitrite, a product of superoxide and nitric oxide, produces coronary vasorelaxation in dogs
    • Liu S., Beckman J.S., Ku D.D. Peroxynitrite, a product of superoxide and nitric oxide, produces coronary vasorelaxation in dogs. J. Pharmacol. Exp. Ther. 1994, 268:1114-1121.
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 1114-1121
    • Liu, S.1    Beckman, J.S.2    Ku, D.D.3
  • 162
    • 0035957630 scopus 로고    scopus 로고
    • Nitric oxide insufficiency, platelet activation, and arterial thrombosis
    • Loscalzo J. Nitric oxide insufficiency, platelet activation, and arterial thrombosis. Circ. Res. 2001, 88:756-762.
    • (2001) Circ. Res. , vol.88 , pp. 756-762
    • Loscalzo, J.1
  • 163
    • 0037231551 scopus 로고    scopus 로고
    • Adverse effects of supplemental L-arginine in atherosclerosis: consequences of methylation stress in a complex catabolism?
    • Loscalzo J. Adverse effects of supplemental L-arginine in atherosclerosis: consequences of methylation stress in a complex catabolism?. Arterioscler Thromb Vasc. Biol. 2003, 23:3-5.
    • (2003) Arterioscler Thromb Vasc. Biol. , vol.23 , pp. 3-5
    • Loscalzo, J.1
  • 164
    • 4744367469 scopus 로고    scopus 로고
    • L-arginine and atherothrombosis
    • discussion 2818S-2819S
    • Loscalzo J. L-arginine and atherothrombosis. J. Nutr. 2004, 134:2798S-2800S. discussion 2818S-2819S.
    • (2004) J. Nutr. , vol.134
    • Loscalzo, J.1
  • 166
    • 0031265794 scopus 로고    scopus 로고
    • Biology of the endothelium
    • II-3-II-10
    • Luscher T.F., Barton M. Biology of the endothelium. Clin. Cardiol. 1997, 20:II-3-II-10.
    • (1997) Clin. Cardiol. , vol.20
    • Luscher, T.F.1    Barton, M.2
  • 167
    • 0141615827 scopus 로고    scopus 로고
    • Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part II
    • Luscher T.F., Creager M.A., Beckman J.A., Cosentino F. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part II. Circulation 2003, 108:1655-1661.
    • (2003) Circulation , vol.108 , pp. 1655-1661
    • Luscher, T.F.1    Creager, M.A.2    Beckman, J.A.3    Cosentino, F.4
  • 168
    • 0030918339 scopus 로고    scopus 로고
    • Hypercholesterolemia impairs a detoxification mechanism against peroxynitrite and renders the vascular tissue more susceptible to oxidative injury
    • Ma X.L., Lopez B.L., Liu G.L., Christopher T.A., Gao F., Guo Y., Feuerstein G.Z., Ruffolo R.R., Barone F.C., Yue T.L. Hypercholesterolemia impairs a detoxification mechanism against peroxynitrite and renders the vascular tissue more susceptible to oxidative injury. Circ. Res. 1997, 80:894-901.
    • (1997) Circ. Res. , vol.80 , pp. 894-901
    • Ma, X.L.1    Lopez, B.L.2    Liu, G.L.3    Christopher, T.A.4    Gao, F.5    Guo, Y.6    Feuerstein, G.Z.7    Ruffolo, R.R.8    Barone, F.C.9    Yue, T.L.10
  • 170
    • 0030795973 scopus 로고    scopus 로고
    • Influence of diabetes mellitus on clinical outcome in the thrombolytic era of acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries
    • Mak K.H., Moliterno D.J., Granger C.B., Miller D.P., White H.D., Wilcox R.G., Califf R.M., Topol E.J. Influence of diabetes mellitus on clinical outcome in the thrombolytic era of acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. J. Am. Coll. Cardiol. 1997, 30:171-179.
    • (1997) J. Am. Coll. Cardiol. , vol.30 , pp. 171-179
    • Mak, K.H.1    Moliterno, D.J.2    Granger, C.B.3    Miller, D.P.4    White, H.D.5    Wilcox, R.G.6    Califf, R.M.7    Topol, E.J.8
  • 171
    • 0034730110 scopus 로고    scopus 로고
    • Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry
    • Malmberg K., Yusuf S., Gerstein H.C., Brown J., Zhao F., Hunt D., Piegas L., Calvin J., Keltai M., Budaj A. Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry. Circulation 2000, 102:1014-1019.
    • (2000) Circulation , vol.102 , pp. 1014-1019
    • Malmberg, K.1    Yusuf, S.2    Gerstein, H.C.3    Brown, J.4    Zhao, F.5    Hunt, D.6    Piegas, L.7    Calvin, J.8    Keltai, M.9    Budaj, A.10
  • 173
    • 51649094903 scopus 로고    scopus 로고
    • Oxidative stress is associated with arterial dysfunction and enhanced intima-media thickness in children with hypercholesterolemia: the potential role of nicotinamide-adenine dinucleotide phosphate oxidase
    • Martino F., Loffredo L., Carnevale R., Sanguigni V., Martino E., Catasca E., Zanoni C., Pignatelli P., Violi F. Oxidative stress is associated with arterial dysfunction and enhanced intima-media thickness in children with hypercholesterolemia: the potential role of nicotinamide-adenine dinucleotide phosphate oxidase. Pediatrics 2008, 122:e648-e655.
    • (2008) Pediatrics , vol.122
    • Martino, F.1    Loffredo, L.2    Carnevale, R.3    Sanguigni, V.4    Martino, E.5    Catasca, E.6    Zanoni, C.7    Pignatelli, P.8    Violi, F.9
  • 174
    • 0033533994 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 overexpression enhances vascular smooth muscle cell migration and alters remodeling in the injured rat carotid artery
    • Mason D.P., Kenagy R.D., Hasenstab D., Bowen-Pope D.F., Seifert R.A., Coats S., Hawkins S.M., Clowes A.W. Matrix metalloproteinase-9 overexpression enhances vascular smooth muscle cell migration and alters remodeling in the injured rat carotid artery. Circ. Res. 1999, 85:1179-1185.
    • (1999) Circ. Res. , vol.85 , pp. 1179-1185
    • Mason, D.P.1    Kenagy, R.D.2    Hasenstab, D.3    Bowen-Pope, D.F.4    Seifert, R.A.5    Coats, S.6    Hawkins, S.M.7    Clowes, A.W.8
  • 175
    • 0035584083 scopus 로고    scopus 로고
    • Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin)
    • Masumoto A., Hirooka Y., Hironaga K., Eshima K., Setoguchi S., Egashira K., Takeshita A. Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin). Am. J. Cardiol. 2001, 88:1291-1294.
    • (2001) Am. J. Cardiol. , vol.88 , pp. 1291-1294
    • Masumoto, A.1    Hirooka, Y.2    Hironaga, K.3    Eshima, K.4    Setoguchi, S.5    Egashira, K.6    Takeshita, A.7
  • 176
    • 25844467055 scopus 로고    scopus 로고
    • Gene delivery of Tim44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats
    • Matsuoka T., Wada J., Hashimoto I., Zhang Y., Eguchi J., Ogawa N., Shikata K., Kanwar Y.S., Makino H. Gene delivery of Tim44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats. Diabetes 2005, 54:2882-2890.
    • (2005) Diabetes , vol.54 , pp. 2882-2890
    • Matsuoka, T.1    Wada, J.2    Hashimoto, I.3    Zhang, Y.4    Eguchi, J.5    Ogawa, N.6    Shikata, K.7    Kanwar, Y.S.8    Makino, H.9
  • 178
    • 0033888287 scopus 로고    scopus 로고
    • Increased expression and activation of stress-activated protein kinases/c-Jun NH(2)-terminal protein kinases in atherosclerotic lesions coincide with p53
    • Metzler B., Hu Y., Dietrich H., Xu Q. Increased expression and activation of stress-activated protein kinases/c-Jun NH(2)-terminal protein kinases in atherosclerotic lesions coincide with p53. Am. J. Pathol. 2000, 156:1875-1886.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1875-1886
    • Metzler, B.1    Hu, Y.2    Dietrich, H.3    Xu, Q.4
  • 179
    • 0026702258 scopus 로고
    • Human umbilical vein endothelial cells submitted to hypoxia-reoxygenation in vitro: implication of free radicals, xanthine oxidase, and energy deficiency
    • Michiels C., Arnould T., Houbion A., Remacle J. Human umbilical vein endothelial cells submitted to hypoxia-reoxygenation in vitro: implication of free radicals, xanthine oxidase, and energy deficiency. J. Cell. Physiol. 1992, 153:53-61.
    • (1992) J. Cell. Physiol. , vol.153 , pp. 53-61
    • Michiels, C.1    Arnould, T.2    Houbion, A.3    Remacle, J.4
  • 184
    • 33746689151 scopus 로고    scopus 로고
    • Novel isoforms of NADPH-oxidase in cerebral vascular control
    • Miller A.A., Drummond G.R., Sobey C.G. Novel isoforms of NADPH-oxidase in cerebral vascular control. Pharmacol. Ther. 2006, 111:928-948.
    • (2006) Pharmacol. Ther. , vol.111 , pp. 928-948
    • Miller, A.A.1    Drummond, G.R.2    Sobey, C.G.3
  • 185
    • 0033527413 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function
    • Milstien S., Katusic Z. Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem. Biophys. Res. Commun. 1999, 263:681-684.
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 681-684
    • Milstien, S.1    Katusic, Z.2
  • 189
    • 0026751947 scopus 로고
    • The 1991 Ulf von Euler Lecture. The L-arginine: nitric oxide pathway
    • Moncada S. The 1991 Ulf von Euler Lecture. The L-arginine: nitric oxide pathway. Acta Physiol. Scand. 1992, 145:201-227.
    • (1992) Acta Physiol. Scand. , vol.145 , pp. 201-227
    • Moncada, S.1
  • 190
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S., Higgs A. The L-arginine-nitric oxide pathway. N. Engl. J. Med. 1993, 329:2002-2012.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 191
    • 0034801560 scopus 로고    scopus 로고
    • Upregulation of vascular NAD(P)H oxidase subunit gp91phox and impairment of the nitric oxide signal transduction pathway in hypertension
    • Morawietz H., Weber M., Rueckschloss U., Lauer N., Hacker A., Kojda G. Upregulation of vascular NAD(P)H oxidase subunit gp91phox and impairment of the nitric oxide signal transduction pathway in hypertension. Biochem. Biophys. Res. Commun. 2001, 285:1130-1135.
    • (2001) Biochem. Biophys. Res. Commun. , vol.285 , pp. 1130-1135
    • Morawietz, H.1    Weber, M.2    Rueckschloss, U.3    Lauer, N.4    Hacker, A.5    Kojda, G.6
  • 192
    • 0031041884 scopus 로고    scopus 로고
    • Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus
    • Morgenstern D.E., Gifford M.A., Li L.L., Doerschuk C.M., Dinauer M.C. Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus. J. Exp. Med. 1997, 185:207-218.
    • (1997) J. Exp. Med. , vol.185 , pp. 207-218
    • Morgenstern, D.E.1    Gifford, M.A.2    Li, L.L.3    Doerschuk, C.M.4    Dinauer, M.C.5
  • 196
    • 0034614284 scopus 로고    scopus 로고
    • Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability
    • Munzel T., Li H., Mollnau H., Hink U., Matheis E., Hartmann M., Oelze M., Skatchkov M., Warnholtz A., Duncker L., Meinertz T., Forstermann U. Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability. Circ. Res. 2000, 86:E7-E12.
    • (2000) Circ. Res. , vol.86
    • Munzel, T.1    Li, H.2    Mollnau, H.3    Hink, U.4    Matheis, E.5    Hartmann, M.6    Oelze, M.7    Skatchkov, M.8    Warnholtz, A.9    Duncker, L.10    Meinertz, T.11    Forstermann, U.12
  • 197
    • 34247847737 scopus 로고    scopus 로고
    • Targeting heme-oxidized soluble guanylate cyclase: solution for all cardiorenal problems in heart failure?
    • Munzel T., Genth-Zotz S., Hink U. Targeting heme-oxidized soluble guanylate cyclase: solution for all cardiorenal problems in heart failure?. Hypertension 2007, 49:974-976.
    • (2007) Hypertension , vol.49 , pp. 974-976
    • Munzel, T.1    Genth-Zotz, S.2    Hink, U.3
  • 198
    • 41649116606 scopus 로고    scopus 로고
    • Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction
    • Munzel T., Sinning C., Post F., Warnholtz A., Schulz E. Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction. Ann. Med. 2008, 40:180-196.
    • (2008) Ann. Med. , vol.40 , pp. 180-196
    • Munzel, T.1    Sinning, C.2    Post, F.3    Warnholtz, A.4    Schulz, E.5
  • 199
    • 0030983708 scopus 로고    scopus 로고
    • Mortality by cause for eight regions of the world: Global Burden of Disease Study
    • Murray C.J., Lopez A.D. Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet 1997, 349:1269-1276.
    • (1997) Lancet , vol.349 , pp. 1269-1276
    • Murray, C.J.1    Lopez, A.D.2
  • 202
    • 0037365968 scopus 로고    scopus 로고
    • Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling
    • Nathan C. Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling. J. Clin. Invest. 2003, 111:769-778.
    • (2003) J. Clin. Invest. , vol.111 , pp. 769-778
    • Nathan, C.1
  • 204
    • 0344541709 scopus 로고    scopus 로고
    • Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic men
    • Nickenig G., Baumer A.T., Temur Y., Kebben D., Jockenhovel F., Bohm M. Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic men. Circulation 1999, 100:2131-2134.
    • (1999) Circulation , vol.100 , pp. 2131-2134
    • Nickenig, G.1    Baumer, A.T.2    Temur, Y.3    Kebben, D.4    Jockenhovel, F.5    Bohm, M.6
  • 206
    • 21644469594 scopus 로고    scopus 로고
    • Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a non-convertible rat liver xanthine dehydrogenase mutant
    • Nishino T., Okamoto K., Kawaguchi Y., Hori H., Matsumura T., Eger B.T., Pai E.F., Nishino T. Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a non-convertible rat liver xanthine dehydrogenase mutant. J. Biol. Chem. 2005, 280:24888-24894.
    • (2005) J. Biol. Chem. , vol.280 , pp. 24888-24894
    • Nishino, T.1    Okamoto, K.2    Kawaguchi, Y.3    Hori, H.4    Matsumura, T.5    Eger, B.T.6    Pai, E.F.7    Nishino, T.8
  • 207
    • 3242785541 scopus 로고    scopus 로고
    • Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men: a prospective cohort study
    • Niskanen L.K., Laaksonen D.E., Nyyssonen K., Alfthan G., Lakka H.M., Lakka T.A., Salonen J.T. Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men: a prospective cohort study. Arch. Intern. Med. 2004, 164:1546-1551.
    • (2004) Arch. Intern. Med. , vol.164 , pp. 1546-1551
    • Niskanen, L.K.1    Laaksonen, D.E.2    Nyyssonen, K.3    Alfthan, G.4    Lakka, H.M.5    Lakka, T.A.6    Salonen, J.T.7
  • 208
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y., Peterson T.E., Harrison D.G. Hypercholesterolemia increases endothelial superoxide anion production. J. Clin. Invest. 1993, 91:2546-2551.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 210
    • 33845620993 scopus 로고    scopus 로고
    • The 'A's and 'O's of NADPH oxidase regulation: a commentary on "Subcellular localization and function of alternatively spliced Noxo1 isoforms"
    • Opitz N., Drummond G.R., Selemidis S., Meurer S., Schmidt H.H. The 'A's and 'O's of NADPH oxidase regulation: a commentary on "Subcellular localization and function of alternatively spliced Noxo1 isoforms". Free Radic. Biol. Med. 2007, 42:175-179.
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 175-179
    • Opitz, N.1    Drummond, G.R.2    Selemidis, S.3    Meurer, S.4    Schmidt, H.H.5
  • 211
    • 0141639811 scopus 로고    scopus 로고
    • Role of monocytes in atherogenesis
    • Osterud B., Bjorklid E. Role of monocytes in atherogenesis. Physiol. Rev. 2003, 83:1069-1112.
    • (2003) Physiol. Rev. , vol.83 , pp. 1069-1112
    • Osterud, B.1    Bjorklid, E.2
  • 214
    • 39849097748 scopus 로고    scopus 로고
    • Redox regulation in the extracellular environment
    • Ottaviano F.G., Handy D.E., Loscalzo J. Redox regulation in the extracellular environment. Circ. J 2008, 72:1-16.
    • (2008) Circ. J , vol.72 , pp. 1-16
    • Ottaviano, F.G.1    Handy, D.E.2    Loscalzo, J.3
  • 215
    • 0032883768 scopus 로고    scopus 로고
    • Nitric oxide-dependent endothelial function is unaffected by allopurinol in hypercholesterolaemic subjects
    • O'Driscoll J.G., Green D.J., Rankin J.M., Taylor R.R. Nitric oxide-dependent endothelial function is unaffected by allopurinol in hypercholesterolaemic subjects. Clin. Exp. Pharmacol. Physiol. 1999, 26:779-783.
    • (1999) Clin. Exp. Pharmacol. Physiol. , vol.26 , pp. 779-783
    • O'Driscoll, J.G.1    Green, D.J.2    Rankin, J.M.3    Taylor, R.R.4
  • 217
    • 38749112555 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction
    • Packard R.R., Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin. Chem. 2008, 54:24-38.
    • (2008) Clin. Chem. , vol.54 , pp. 24-38
    • Packard, R.R.1    Libby, P.2
  • 218
    • 14044254273 scopus 로고    scopus 로고
    • Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: relationship to oxidative stress
    • Pagnin E., Fadini G., de Toni R., Tiengo A., Calo L., Avogaro A. Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: relationship to oxidative stress. J. Clin. Endocrinol Metab. 2005, 90:1130-1136.
    • (2005) J. Clin. Endocrinol Metab. , vol.90 , pp. 1130-1136
    • Pagnin, E.1    Fadini, G.2    de Toni, R.3    Tiengo, A.4    Calo, L.5    Avogaro, A.6
  • 219
    • 4243206075 scopus 로고    scopus 로고
    • "Endothelium, nitric oxide, and atherosclerosis"
    • Panza, J. (1999). "Endothelium, nitric oxide, and atherosclerosis.".
    • (1999)
    • Panza, J.1
  • 220
  • 221
    • 41149150716 scopus 로고    scopus 로고
    • NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities
    • Paravicini T.M., Touyz R.M. NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 2008, 31(Suppl 2):S170-S180.
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL.2
    • Paravicini, T.M.1    Touyz, R.M.2
  • 223
    • 0030779576 scopus 로고    scopus 로고
    • Plasma and vascular tissue arginine are decreased in diabetes: acute arginine supplementation restores endothelium-dependent relaxation by augmenting cGMP production
    • Pieper G.M., Dondlinger L.A. Plasma and vascular tissue arginine are decreased in diabetes: acute arginine supplementation restores endothelium-dependent relaxation by augmenting cGMP production. J. Pharmacol. Exp. Ther. 1997, 283:684-691.
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 684-691
    • Pieper, G.M.1    Dondlinger, L.A.2
  • 225
    • 0025750850 scopus 로고
    • Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells
    • Pollock J.S., Forstermann U., Mitchell J.A., Warner T.D., Schmidt H.H., Nakane M., Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc. Natl. Acad. Sci. U S A 1991, 88:10480-10484.
    • (1991) Proc. Natl. Acad. Sci. U S A , vol.88 , pp. 10480-10484
    • Pollock, J.S.1    Forstermann, U.2    Mitchell, J.A.3    Warner, T.D.4    Schmidt, H.H.5    Nakane, M.6    Murad, F.7
  • 226
    • 0026470180 scopus 로고
    • Generation of superoxide by purified brain nitric oxide synthase
    • Pou S., Pou W.S., Bredt D.S., Snyder S.H., Rosen G.M. Generation of superoxide by purified brain nitric oxide synthase. J. Biol. Chem. 1992, 267:24173-24176.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24173-24176
    • Pou, S.1    Pou, W.S.2    Bredt, D.S.3    Snyder, S.H.4    Rosen, G.M.5
  • 228
    • 21744434763 scopus 로고    scopus 로고
    • Mitochondrial dysfunction as an initiating event in atherogenesis: a plausible hypothesis
    • Puddu P., Puddu G.M., Galletti L., Cravero E., Muscari A. Mitochondrial dysfunction as an initiating event in atherogenesis: a plausible hypothesis. Cardiology 2005, 103:137-141.
    • (2005) Cardiology , vol.103 , pp. 137-141
    • Puddu, P.1    Puddu, G.M.2    Galletti, L.3    Cravero, E.4    Muscari, A.5
  • 230
    • 0031031871 scopus 로고    scopus 로고
    • Coronary vascular nitric oxide activity in hypertension and hypercholesterolemia. Comparison of acetylcholine and substance P.
    • Quyyumi A.A., Mulcahy D., Andrews N.P., Husain S., Panza J.A., Cannon R.O. Coronary vascular nitric oxide activity in hypertension and hypercholesterolemia. Comparison of acetylcholine and substance P. Circulation 1997, 95:104-110.
    • (1997) Circulation , vol.95 , pp. 104-110
    • Quyyumi, A.A.1    Mulcahy, D.2    Andrews, N.P.3    Husain, S.4    Panza, J.A.5    Cannon, R.O.6
  • 231
    • 33644857154 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase: host defense enzyme of the endothelium?
    • Rabelink T.J., Luscher T.F. Endothelial nitric oxide synthase: host defense enzyme of the endothelium?. Arterioscler Thromb Vasc. Biol. 2006, 26:267-271.
    • (2006) Arterioscler Thromb Vasc. Biol. , vol.26 , pp. 267-271
    • Rabelink, T.J.1    Luscher, T.F.2
  • 233
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
    • Rajagopalan S., Kurz S., Munzel T., Tarpey M., Freeman B.A., Griendling K.K., Harrison D.G. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J. Clin. Invest. 1996, 97:1916-1923.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3    Tarpey, M.4    Freeman, B.A.5    Griendling, K.K.6    Harrison, D.G.7
  • 235
    • 14644419622 scopus 로고    scopus 로고
    • Proatherosclerotic mechanisms involving protein kinase C in diabetes and insulin resistance
    • Rask-Madsen C., King G.L. Proatherosclerotic mechanisms involving protein kinase C in diabetes and insulin resistance. Arterioscler Thromb Vasc. Biol. 2005, 25:487-496.
    • (2005) Arterioscler Thromb Vasc. Biol. , vol.25 , pp. 487-496
    • Rask-Madsen, C.1    King, G.L.2
  • 237
    • 59649109442 scopus 로고    scopus 로고
    • Modulation of endothelium and endothelial progenitor cell function by low-density lipoproteins: implication for vascular repair, angiogenesis and vasculogenesis
    • Rodriguez C., Slevin M., Rodriguez-Calvo R., Kumar S., Krupinski J., Tejerina T., Martinez-Gonzalez J. Modulation of endothelium and endothelial progenitor cell function by low-density lipoproteins: implication for vascular repair, angiogenesis and vasculogenesis. Pathobiology 2009, 76:11-22.
    • (2009) Pathobiology , vol.76 , pp. 11-22
    • Rodriguez, C.1    Slevin, M.2    Rodriguez-Calvo, R.3    Kumar, S.4    Krupinski, J.5    Tejerina, T.6    Martinez-Gonzalez, J.7
  • 240
    • 0032849088 scopus 로고    scopus 로고
    • New insights into the regulation of protein kinase C and novel phorbol ester receptors
    • Ron D., Kazanietz M.G. New insights into the regulation of protein kinase C and novel phorbol ester receptors. FASEB J 1999, 13:1658-1676.
    • (1999) FASEB J , vol.13 , pp. 1658-1676
    • Ron, D.1    Kazanietz, M.G.2
  • 241
    • 0025906819 scopus 로고
    • L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits
    • Rossitch E., Alexander E., Black P.M., Cooke J.P. L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits. J. Clin. Invest. 1991, 87:1295-1299.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1295-1299
    • Rossitch, E.1    Alexander, E.2    Black, P.M.3    Cooke, J.P.4
  • 244
    • 0030033842 scopus 로고    scopus 로고
    • Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells
    • Sarkar R., Meinberg E.G., Stanley J.C., Gordon D., Webb R.C. Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells. Circ. Res. 1996, 78:225-230.
    • (1996) Circ. Res. , vol.78 , pp. 225-230
    • Sarkar, R.1    Meinberg, E.G.2    Stanley, J.C.3    Gordon, D.4    Webb, R.C.5
  • 245
    • 0032211819 scopus 로고    scopus 로고
    • Oxidized LDL activates fas-mediated endothelial cell apoptosis
    • Sata M., Walsh K. Oxidized LDL activates fas-mediated endothelial cell apoptosis. J. Clin. Invest. 1998, 102:1682-1689.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1682-1689
    • Sata, M.1    Walsh, K.2
  • 246
    • 20444458775 scopus 로고    scopus 로고
    • Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair
    • Schmidt-Lucke C., Rossig L., Fichtlscherer S., Vasa M., Britten M., Kamper U., Dimmeler S., Zeiher A.M. Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair. Circulation 2005, 111:2981-2987.
    • (2005) Circulation , vol.111 , pp. 2981-2987
    • Schmidt-Lucke, C.1    Rossig, L.2    Fichtlscherer, S.3    Vasa, M.4    Britten, M.5    Kamper, U.6    Dimmeler, S.7    Zeiher, A.M.8
  • 247
    • 55449118234 scopus 로고    scopus 로고
    • Chemokines in vascular dysfunction and remodeling
    • Schober A. Chemokines in vascular dysfunction and remodeling. Arterioscler Thromb Vasc. Biol. 2008, 28:1950-1959.
    • (2008) Arterioscler Thromb Vasc. Biol. , vol.28 , pp. 1950-1959
    • Schober, A.1
  • 248
    • 0037184495 scopus 로고    scopus 로고
    • Molecular understanding of hyperglycemia's adverse effects for diabetic complications
    • Sheetz M.J., King G.L. Molecular understanding of hyperglycemia's adverse effects for diabetic complications. JAMA 2002, 288:2579-2588.
    • (2002) JAMA , vol.288 , pp. 2579-2588
    • Sheetz, M.J.1    King, G.L.2
  • 249
    • 0242298632 scopus 로고    scopus 로고
    • Role of neutral amino acid transport and protein breakdown for substrate supply of nitric oxide synthase in human endothelial cells
    • Simon A., Plies L., Habermeier A., Martine U., Reining M., Closs E.I. Role of neutral amino acid transport and protein breakdown for substrate supply of nitric oxide synthase in human endothelial cells. Circ. Res. 2003, 93:813-820.
    • (2003) Circ. Res. , vol.93 , pp. 813-820
    • Simon, A.1    Plies, L.2    Habermeier, A.3    Martine, U.4    Reining, M.5    Closs, E.I.6
  • 252
    • 0032564864 scopus 로고    scopus 로고
    • Uncoupling: new approaches to an old problem of bioenergetics
    • Skulachev V.P. Uncoupling: new approaches to an old problem of bioenergetics. Biochim. Biophys. Acta 1998, 1363:100-124.
    • (1998) Biochim. Biophys. Acta , vol.1363 , pp. 100-124
    • Skulachev, V.P.1
  • 254
    • 0030667160 scopus 로고    scopus 로고
    • Inhibition of endothelial vascular cell adhesion molecule-1 expression by nitric oxide involves the induction and nuclear translocation of IkappaBalpha
    • Spiecker M., Peng H.B., Liao J.K. Inhibition of endothelial vascular cell adhesion molecule-1 expression by nitric oxide involves the induction and nuclear translocation of IkappaBalpha. J. Biol. Chem. 1997, 272:30969-30974.
    • (1997) J. Biol. Chem. , vol.272 , pp. 30969-30974
    • Spiecker, M.1    Peng, H.B.2    Liao, J.K.3
  • 255
    • 0037453094 scopus 로고    scopus 로고
    • Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation
    • Spiekermann S., Landmesser U., Dikalov S., Bredt M., Gamez G., Tatge H., Reepschlager N., Hornig B., Drexler H., Harrison D.G. Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation 2003, 107:1383-1389.
    • (2003) Circulation , vol.107 , pp. 1383-1389
    • Spiekermann, S.1    Landmesser, U.2    Dikalov, S.3    Bredt, M.4    Gamez, G.5    Tatge, H.6    Reepschlager, N.7    Hornig, B.8    Drexler, H.9    Harrison, D.G.10
  • 256
    • 0024439993 scopus 로고
    • Comparison of biochemical properties of liver arginase from streptozocin-induced diabetic and control mice
    • Spolarics Z., Bond J.S. Comparison of biochemical properties of liver arginase from streptozocin-induced diabetic and control mice. Arch. Biochem. Biophys. 1989, 274:426-433.
    • (1989) Arch. Biochem. Biophys. , vol.274 , pp. 426-433
    • Spolarics, Z.1    Bond, J.S.2
  • 257
    • 0001249135 scopus 로고
    • The regulation of the energy output of the heart
    • Starling E.H., Visscher M.B. The regulation of the energy output of the heart. J. Physiol. 1927, 62:243-261.
    • (1927) J. Physiol. , vol.62 , pp. 243-261
    • Starling, E.H.1    Visscher, M.B.2
  • 258
    • 33644851056 scopus 로고    scopus 로고
    • Tissue factor in cardiovascular diseases: molecular mechanisms and clinical implications
    • Steffel J., Luscher T.F., Tanner F.C. Tissue factor in cardiovascular diseases: molecular mechanisms and clinical implications. Circulation 2006, 113:722-731.
    • (2006) Circulation , vol.113 , pp. 722-731
    • Steffel, J.1    Luscher, T.F.2    Tanner, F.C.3
  • 259
    • 33847613258 scopus 로고    scopus 로고
    • Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin
    • Steffen Y., Jung T., Klotz L.O., Schewe T., Grune T., Sies H. Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin. Free Radic. Biol. Med. 2007, 42:955-970.
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 955-970
    • Steffen, Y.1    Jung, T.2    Klotz, L.O.3    Schewe, T.4    Grune, T.5    Sies, H.6
  • 260
    • 0024603895 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberg D., Parthasarathy S., Carew T.E., Khoo J.C., Witztum J.L. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 1989, 320:915-924.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 261
    • 0000061171 scopus 로고
    • Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids
    • Steinbrecher U.P., Parthasarathy S., Leake D.S., Witztum J.L., Steinberg D. Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc. Natl. Acad. Sci. U S A 1984, 81:3883-3887.
    • (1984) Proc. Natl. Acad. Sci. U S A , vol.81 , pp. 3883-3887
    • Steinbrecher, U.P.1    Parthasarathy, S.2    Leake, D.S.3    Witztum, J.L.4    Steinberg, D.5
  • 264
    • 1242273844 scopus 로고    scopus 로고
    • ADMA and oxidative stress
    • Sydow K., Munzel T. ADMA and oxidative stress. Atheroscler 2003, 4(Suppl):41-51.
    • (2003) Atheroscler , vol.4 , Issue.SUPPL , pp. 41-51
    • Sydow, K.1    Munzel, T.2
  • 266
    • 33750897683 scopus 로고    scopus 로고
    • Regulation of novel superoxide-producing NAD(P)H oxidases
    • Takeya R., Sumimoto H. Regulation of novel superoxide-producing NAD(P)H oxidases. Antioxid Redox Signal 2006, 8:1523-1532.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1523-1532
    • Takeya, R.1    Sumimoto, H.2
  • 267
    • 0024388901 scopus 로고
    • Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor
    • Tayeh M.A., Marletta M.A. Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor. J. Biol. Chem. 1989, 264:19654-19658.
    • (1989) J. Biol. Chem. , vol.264 , pp. 19654-19658
    • Tayeh, M.A.1    Marletta, M.A.2
  • 268
    • 0028274304 scopus 로고
    • Free radicals in diabetic endothelial cell dysfunction
    • Tesfamariam B. Free radicals in diabetic endothelial cell dysfunction. Free Radic. Biol. Med. 1994, 16:383-391.
    • (1994) Free Radic. Biol. Med. , vol.16 , pp. 383-391
    • Tesfamariam, B.1
  • 269
    • 0025832494 scopus 로고
    • Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C
    • Tesfamariam B., Brown M.L., Cohen R.A. Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C. J. Clin. Invest. 1991, 87:1643-1648.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1643-1648
    • Tesfamariam, B.1    Brown, M.L.2    Cohen, R.A.3
  • 270
    • 49849084827 scopus 로고    scopus 로고
    • Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities
    • Thomas S.R., Witting P.K., Drummond G.R. Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal 2008, 10:1713-1765.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1713-1765
    • Thomas, S.R.1    Witting, P.K.2    Drummond, G.R.3
  • 272
    • 0043075965 scopus 로고    scopus 로고
    • Up-regulation of vascular and renal mitogen-activated protein kinases in hypertensive rats is normalized by inhibitors of the Na+/Mg2+ exchanger
    • Touyz R.M., Yao G. Up-regulation of vascular and renal mitogen-activated protein kinases in hypertensive rats is normalized by inhibitors of the Na+/Mg2+ exchanger. Clin. Sci. (Lond) 2003, 105:235-242.
    • (2003) Clin. Sci. (Lond) , vol.105 , pp. 235-242
    • Touyz, R.M.1    Yao, G.2
  • 273
    • 0037783377 scopus 로고    scopus 로고
    • C-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells
    • Touyz R.M., Yao G., Schiffrin E.L. c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells. Arterioscler Thromb. Vasc. Biol. 2003, 23:981-987.
    • (2003) Arterioscler Thromb. Vasc. Biol. , vol.23 , pp. 981-987
    • Touyz, R.M.1    Yao, G.2    Schiffrin, E.L.3
  • 274
    • 2642551439 scopus 로고    scopus 로고
    • Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells
    • Touyz R.M., Yao G., Viel E., Amiri F., Schiffrin E.L. Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells. J. Hypertens 2004, 22:1141-1149.
    • (2004) J. Hypertens , vol.22 , pp. 1141-1149
    • Touyz, R.M.1    Yao, G.2    Viel, E.3    Amiri, F.4    Schiffrin, E.L.5
  • 275
    • 0034737984 scopus 로고    scopus 로고
    • Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques
    • Tricot O., Mallat Z., Heymes C., Belmin J., Leseche G., Tedgui A. Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques. Circulation 2000, 101:2450-2453.
    • (2000) Circulation , vol.101 , pp. 2450-2453
    • Tricot, O.1    Mallat, Z.2    Heymes, C.3    Belmin, J.4    Leseche, G.5    Tedgui, A.6
  • 277
    • 0024271322 scopus 로고
    • Aging and vascular responsiveness
    • Vanhoutte P.M. Aging and vascular responsiveness. J. Cardiovasc. Pharmacol. 1988, 12(Suppl 8):S11-S19.
    • (1988) J. Cardiovasc. Pharmacol. , vol.12 , Issue.SUPPL.8
    • Vanhoutte, P.M.1
  • 278
    • 17644433975 scopus 로고    scopus 로고
    • Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
    • Vasa M., Fichtlscherer S., Aicher A., Adler K., Urbich C., Martin H., Zeiher A.M., Dimmeler S. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ. Res. 2001, 89:E1-E7.
    • (2001) Circ. Res. , vol.89
    • Vasa, M.1    Fichtlscherer, S.2    Aicher, A.3    Adler, K.4    Urbich, C.5    Martin, H.6    Zeiher, A.M.7    Dimmeler, S.8
  • 280
    • 0037086565 scopus 로고    scopus 로고
    • The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study
    • Vasquez-Vivar J., Martasek P., Whitsett J., Joseph J., Kalyanaraman B. The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study. Biochem. J 2002, 362:733-739.
    • (2002) Biochem. J , vol.362 , pp. 733-739
    • Vasquez-Vivar, J.1    Martasek, P.2    Whitsett, J.3    Joseph, J.4    Kalyanaraman, B.5
  • 281
    • 55949104898 scopus 로고    scopus 로고
    • ADMA impairs nitric oxide-mediated arteriolar function due to increased superoxide production by angiotensin II-NAD(P)H oxidase pathway
    • Veresh Z., Racz A., Lotz G., Koller A. ADMA impairs nitric oxide-mediated arteriolar function due to increased superoxide production by angiotensin II-NAD(P)H oxidase pathway. Hypertension 2008, 52:960-966.
    • (2008) Hypertension , vol.52 , pp. 960-966
    • Veresh, Z.1    Racz, A.2    Lotz, G.3    Koller, A.4
  • 283
    • 28644439825 scopus 로고    scopus 로고
    • The protein kinase C-beta inhibitor, ruboxistaurin, for the treatment of diabetic microvascular complications
    • Vinik A. The protein kinase C-beta inhibitor, ruboxistaurin, for the treatment of diabetic microvascular complications. Expert Opin. Investig. Drugs 2005, 14:1547-1559.
    • (2005) Expert Opin. Investig. Drugs , vol.14 , pp. 1547-1559
    • Vinik, A.1
  • 284
    • 1642276271 scopus 로고    scopus 로고
    • Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice
    • Virdis A., Neves M.F., Amiri F., Touyz R.M., Schiffrin E.L. Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. J. Hypertens 2004, 22:535-542.
    • (2004) J. Hypertens , vol.22 , pp. 535-542
    • Virdis, A.1    Neves, M.F.2    Amiri, F.3    Touyz, R.M.4    Schiffrin, E.L.5
  • 286
    • 0034889663 scopus 로고    scopus 로고
    • Endothelium-dependent vasodilation is independent of the plasma L-arginine/ADMA ratio in men with stable angina: lack of effect of oral L-arginine on endothelial function, oxidative stress and exercise performance
    • Walker H.A., McGing E., Fisher I., Boger R.H., Bode-Boger S.M., Jackson G., Ritter J.M., Chowienczyk P.J. Endothelium-dependent vasodilation is independent of the plasma L-arginine/ADMA ratio in men with stable angina: lack of effect of oral L-arginine on endothelial function, oxidative stress and exercise performance. J. Am. Coll. Cardiol. 2001, 38:499-505.
    • (2001) J. Am. Coll. Cardiol. , vol.38 , pp. 499-505
    • Walker, H.A.1    McGing, E.2    Fisher, I.3    Boger, R.H.4    Bode-Boger, S.M.5    Jackson, G.6    Ritter, J.M.7    Chowienczyk, P.J.8
  • 289
    • 33749674128 scopus 로고    scopus 로고
    • Improvement of endothelial function by systemic transfusion of vascular progenitor cells
    • Wassmann S., Werner N., Czech T., Nickenig G. Improvement of endothelial function by systemic transfusion of vascular progenitor cells. Circ. Res. 2006, 99:e74-e83.
    • (2006) Circ. Res. , vol.99
    • Wassmann, S.1    Werner, N.2    Czech, T.3    Nickenig, G.4
  • 293
    • 22444433668 scopus 로고    scopus 로고
    • Oxidant and redox signaling in vascular oxygen sensing mechanisms: basic concepts, current controversies, and potential importance of cytosolic NADPH
    • Wolin M.S., Ahmad M., Gupte S.A. Oxidant and redox signaling in vascular oxygen sensing mechanisms: basic concepts, current controversies, and potential importance of cytosolic NADPH. Am. J. Physiol. Lung Cell Mol. Physiol. 2005, 289:L159-L173.
    • (2005) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.289
    • Wolin, M.S.1    Ahmad, M.2    Gupte, S.A.3
  • 294
    • 0024260976 scopus 로고
    • Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester
    • Wu K.K., Hatzakis H., Lo S.S., Seong D.C., Sanduja S.K., Tai H.H. Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester. J. Biol. Chem. 1988, 263:19043-19047.
    • (1988) J. Biol. Chem. , vol.263 , pp. 19043-19047
    • Wu, K.K.1    Hatzakis, H.2    Lo, S.S.3    Seong, D.C.4    Sanduja, S.K.5    Tai, H.H.6
  • 295
    • 0030033536 scopus 로고    scopus 로고
    • Acute hypertension activates mitogen-activated protein kinases in arterial wall
    • Xu Q., Liu Y., Gorospe M., Udelsman R., Holbrook N.J. Acute hypertension activates mitogen-activated protein kinases in arterial wall. J. Clin. Invest. 1996, 97:508-514.
    • (1996) J. Clin. Invest. , vol.97 , pp. 508-514
    • Xu, Q.1    Liu, Y.2    Gorospe, M.3    Udelsman, R.4    Holbrook, N.J.5
  • 297
    • 0033392430 scopus 로고    scopus 로고
    • Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-kappaB activation
    • Yan Z.Q., Sirsjo A., Bochaton-Piallat M.L., Gabbiani G., Hansson G.K. Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-kappaB activation. Arterioscler Thromb. Vasc. Biol. 1999, 19:2854-2862.
    • (1999) Arterioscler Thromb. Vasc. Biol. , vol.19 , pp. 2854-2862
    • Yan, Z.Q.1    Sirsjo, A.2    Bochaton-Piallat, M.L.3    Gabbiani, G.4    Hansson, G.K.5
  • 299
    • 34447635066 scopus 로고    scopus 로고
    • Identification of c-Jun N-terminal kinase as a therapeutic target for abdominal aortic aneurysm
    • Yoshimura K., Aoki H., Ikeda Y., Furutani A., Hamano K., Matsuzaki M. Identification of c-Jun N-terminal kinase as a therapeutic target for abdominal aortic aneurysm. Ann. N Y Acad. Sci. 2006, 1085:403-406.
    • (2006) Ann. N Y Acad. Sci. , vol.1085 , pp. 403-406
    • Yoshimura, K.1    Aoki, H.2    Ikeda, Y.3    Furutani, A.4    Hamano, K.5    Matsuzaki, M.6
  • 300
    • 0035960630 scopus 로고    scopus 로고
    • Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization
    • Yusuf S., Reddy S., Ounpuu S., Anand S. Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization. Circulation 2001, 104:2746-2753.
    • (2001) Circulation , vol.104 , pp. 2746-2753
    • Yusuf, S.1    Reddy, S.2    Ounpuu, S.3    Anand, S.4
  • 301
    • 0028929453 scopus 로고
    • Tissue endothelin-1 immunoreactivity in the active coronary atherosclerotic plaque. A clue to the mechanism of increased vasoreactivity of the culprit lesion in unstable angina
    • Zeiher A.M., Goebel H., Schachinger V., Ihling C. Tissue endothelin-1 immunoreactivity in the active coronary atherosclerotic plaque. A clue to the mechanism of increased vasoreactivity of the culprit lesion in unstable angina. Circulation 1995, 91:941-947.
    • (1995) Circulation , vol.91 , pp. 941-947
    • Zeiher, A.M.1    Goebel, H.2    Schachinger, V.3    Ihling, C.4
  • 302
    • 50249123892 scopus 로고    scopus 로고
    • The role of inflammatory cytokines in endothelial dysfunction
    • Zhang C. The role of inflammatory cytokines in endothelial dysfunction. Basic Res. Cardiol. 2008, 103:398-406.
    • (2008) Basic Res. Cardiol. , vol.103 , pp. 398-406
    • Zhang, C.1
  • 303
    • 0035347173 scopus 로고    scopus 로고
    • Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function
    • Zhang C., Hein T.W., Wang W., Chang C.I., Kuo L. Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function. FASEB J 2001, 15:1264-1266.
    • (2001) FASEB J , vol.15 , pp. 1264-1266
    • Zhang, C.1    Hein, T.W.2    Wang, W.3    Chang, C.I.4    Kuo, L.5
  • 304
    • 9644282852 scopus 로고    scopus 로고
    • Upregulation of vascular arginase in hypertension decreases nitric oxide-mediated dilation of coronary arterioles
    • Zhang C., Hein T.W., Wang W., Miller M.W., Fossum T.W., McDonald M.M., Humphrey J.D., Kuo L. Upregulation of vascular arginase in hypertension decreases nitric oxide-mediated dilation of coronary arterioles. Hypertension 2004, 44:935-943.
    • (2004) Hypertension , vol.44 , pp. 935-943
    • Zhang, C.1    Hein, T.W.2    Wang, W.3    Miller, M.W.4    Fossum, T.W.5    McDonald, M.M.6    Humphrey, J.D.7    Kuo, L.8
  • 305
    • 31544440725 scopus 로고    scopus 로고
    • Activation of JNK and xanthine oxidase by TNF-alpha impairs nitric oxide-mediated dilation of coronary arterioles
    • Zhang C., Hein T.W., Wang W., Ren Y., Shipley R.D., Kuo L. Activation of JNK and xanthine oxidase by TNF-alpha impairs nitric oxide-mediated dilation of coronary arterioles. J. Mol. Cell Cardiol. 2006, 40:247-257.
    • (2006) J. Mol. Cell Cardiol. , vol.40 , pp. 247-257
    • Zhang, C.1    Hein, T.W.2    Wang, W.3    Ren, Y.4    Shipley, R.D.5    Kuo, L.6


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