Activation of JNK and xanthine oxidase by TNF-α impairs nitric oxide-mediated dilation of coronary arterioles

Journal of Molecular and Cellular Cardiology

Volumn 40, Issue 2, 2006, Pages 247-257

  Zhang, Cuihua ^a,b   Hein, Travis W ^a,c   Wang, Wei ^a   Ren, Yi ^a   Shipley, Robert D ^a   Kuo, Lih ^a  

^a TEXAS A AND M UNIVERSITY SYSTEM   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

Author keywords

c Jun N terminal kinase; Nitric oxide; Tumor necrosis factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOSINE; ALLOPURINOL; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOCYNIN; CERAMIDE; DICOUMAROL; DIMETHYLAMINOPURINE; MITOGEN ACTIVATED PROTEIN KINASE; N(G) METHYLARGININE; NITRIC OXIDE; ROTENONE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ARTICLE; CORONARY ARTERY; CORONARY ARTERY DILATATION; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; HISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SWINE;

ADENOSINE; ANIMALS; ARTERIOLES; CERAMIDES; CORONARY VESSELS; ELECTRON TRANSPORT; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; NADPH OXIDASE; NITRIC OXIDE; SIGNAL TRANSDUCTION; SPHINGOMYELIN PHOSPHODIESTERASE; SUPEROXIDES; SWINE; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR DISEASES; VASODILATION; XANTHINE OXIDASE;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 31544440725     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2005.11.010     Document Type: Article

References (70)

1. C.P. Maury, and A.M. Teppo Circulating tumour necrosis factor-alpha (cachectin) in myocardial infarction J. Intern. Med. 225 1989 333 336
2. Y. Basaran, M.M. Basaran, K.F. Babacan, B. Ener, T. Okay, and H. Gok Serum tumor necrosis factor levels in acute myocardial infarction and unstable angina pectoris Angiology 44 1993 332 337
3. F. Squadrito, A. Domenica, B. Zingarelli, M. Ioculano, G. Calapai, and G.M. Campo Tumor necrosis factor involvement in myocardial ischaemia-reperfusion injury Eur. J. Pharmacol. 237 1993 223 230
4. J. Gurevitch, I. Frolkis, Y. Yuhas, Y. Paz, M. Matsa, and R. Mohr Tumor necrosis factor-alpha is released from the isolated heart undergoing ischemia and reperfusion J. Am. Coll. Cardiol. 28 1996 247 252
5. J. Gurevitch, I.F., Y. Yuhas, B. Lifschitz-Mercer, E. Berger, and Y. Paz Anti-tumor necrosis factor-alpha improves myocardial recovery after ischemia and reperfusion J. Am. Coll. Cardiol. 30 1997 1554 1561
6. P. Barath, M.C. Fishbein, J. Cao, J. Berenson, R.H. Helfant, and J.S. Forrester Detection and localization of tumor necrosis factor in human atheroma Am. J. Cardiol. 65 1990 297 302
7. B. Levine, J. Kalman, L. Mayer, H. Fillit, and M. Packer Elevated circulating levels of tumor necrosis factor in severe chronic heart failure N. Engl. J. Med. 323 1990 236 241
8. S. Fichtlscherer, L. Rossig, S. Breuer, M. Vasa, S. Dimmeler, and A.M. Zeiher Tumor necrosis factor antagonism with etanercept improves systemic endothelial vasoreactivity in patients with advanced heart failure Circulation 104 2001 3023 3025
9. C. Seiler, T. Pohl, M. Billinger, and B. Meier Tumour necrosis factor alpha concentration and collateral flow in patients with coronary artery disease and normal systolic left ventricular function Heart 89 2003 96 97
10. V. Schachinger, M.B. Britten, and A.M. Zeiher Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease Circulation 101 2000 1899 1906
11. R. Nakamura, K. Egashira, K. Arimura, Y. Machida, T. Ide, and H. Tsutsui Increased inactivation of nitric oxide is involved in impaired coronary flow reserve in heart failure Am. J. Physiol. Heart Circ. Physiol. 281 2001 H2619 H2625
12. A.M. Zeiher, H. Drexler, H. Wollschläger, and H. Just Endothelial dysfunction of the coronary microvasculature is associated with impaired coronary blood flow regulation in patients with early atherosclerosis Circulation 84 1991 1984 1992
13. C. Tentolouris, D. Tousoulis, C. Antoniades, E. Bosinakou, M. Kotsopoulou, and A. Trikas Endothelial function and proinflammatory cytokines in patients with ischemic heart disease and dilated cardiomyopathy Int. J. Cardiol. 94 2004 301 305
14. F. Kim, B. Gallis, and M.A. Corson TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells Am. J. Physiol. Cell Physiol. 280 2001 C1057 C1065
15. W.M. Chilian, C.L. Eastham, and M.L. Marcus Microvascular distribution of coronary vascular resistance in beating left ventricle Am. J. Physiol. 251 1986 H779 H788
16. J.M. Li, A.M. Mullen, S. Yun, F. Wientjes, G.Y. Brouns, and A.J. Thrasher Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha Circ. Res. 90 2002 143 150
17. H.P. Friedl, G.O. Till, U.S. Ryan, and P.A. Ward Mediator-induced activation of xanthine oxidase in endothelial cells FASEB J. 3 1989 2512 2518
18. S. Corda, C. Laplace, E. Vicaut, and J. Duranteau Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-alpha is mediated by ceramide Am. J. Respir. Cell Mol. Biol. 24 2001 762 768
19. L.A. Madge, and J.S. Pober TNF signaling in vascular endothelial cells Exp. Mol. Pathol. 70 2001 317 325
20. D.X. Zhang, A.P. Zou, and P.L. Li Ceramide reduces endothelium-dependent vasodilation by increasing superoxide production in small bovine coronary arteries Circ. Res. 88 2001 824 831
21. S. Mathias, L.A. Pena, and R.N. Kolesnick Signal transduction of stress via ceramide Biochem. J. 335 1998 465 480
22. L. Kuo, W.M. Chilian, and M.J. Davis Interaction of pressure- and flow-induced responses in porcine coronary resistance vessels Am. J. Physiol. Heart Circ. Physiol. 261 1991 H1706 H1715
23. ATP channels Circ. Res. 85 1999 634 642
24. C. Zhang, T.W. Hein, W. Wang, C.I. Chang, and L. Kuo Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function FASEB J. 15 2001 1264 1266
25. D.X. Zhang, F.X. Yi, A.P. Zou, and P.L. Li Role of ceramide in TNF-α-induced impairment of endothelium-dependent vasorelaxation in coronary arteries Am. J. Physiol. Heart Circ. Physiol. 283 2002 H1785 H1794
26. K. Bhagat, and P. Vallance Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo Circulation 96 1997 3042 3047
27. A. Erdreich-Epstein, L.B. Tran, O.T. Cox, E.Y. Huang, W.E. Laug, and H. Shimada Endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 involves ceramide metabolic pathways Blood 105 2005 4353 4361
28. C.M. Pilane, and E.F. LaBelle NO induced apoptosis of vascular smooth muscle cells accompanied by ceramide increase J. Cell. Physiol. 199 2004 310 315
29. M.W. Marino, J.D. Dunbar, L.W. Wu, J.R. Ngaiza, H.M. Han, and D. Guo Inhibition of tumor necrosis factor signal transduction in endothelial cells by dimethylaminopurine J. Biol. Chem. 271 1996 28624 28629
30. 2 receptors in modulating coronary microvascular function Circ. Res. 92 2003 322 329
31. 2α Hypertension 33 1999 424 428
32. E. Qamirani, Y. Ren, L. Kuo, and T.W. Hein C-reactive protein inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by activating p38 kinase and NAD(P)H oxidase Arterioscler. Thromb. Vasc. Biol. 25 2005 995 1001
33. F. Borges, E. Fernandes, and F. Roleira Progress towards the discovery of xanthine oxidase inhibitors Curr. Med. Chem. 9 2002 195 217
34. 2 generation play a key role in flow-mediated dilation in human coronary resistance arteries Circ. Res. 93 2003 573 580
35. R.A. Beswick, A.M. Dorrance, R. Leite, and R.C. Webb NADH/NADPH oxidase and enhanced superoxide production in the mineralcorticoid hypertensive rat Hypertension 38 2001 1107 1111
36. B.L. Bennett, D.T. Sasaki, B.W. Murray, E.C. O'Leary, S.T. Sakata, and W. Xu SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase Proc. Natl. Acad. Sci. USA 98 2001 13681 13686
37. D. Krause, A. Lyons, C. Fennelly, and R. O'Connor Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol J. Biol. Chem. 276 2001 19244 19252
38. P.F. Cirillo, C. Pargellis, and J. Regan The non-diaryl heterocycle classes of p38 MAP kinase inhibitors Curr. Top. Med. Chem. 2 2002 1021 1035
39. R.A. Oeckler, P.M. Kaminski, and M.S. Wolin Stretch enhances contraction of bovine coronary arteries via an NAD(P)H oxidase-mediated activation of the extracellular signal-regulated kinase mitogen-activated protein kinase cascade Circ. Res. 92 2003 23 31
40. T.W. Hein, J.C. Liao, and L. Kuo oxLDL specifically impairs endothelium-dependent, NO-mediated dilation of coronary arterioles Am. J. Physiol. Heart Circ. Physiol. 278 2000 H175 H183
41. S. Kofler, T. Nickel, and M. Weis Roles of cytokines in cardiovascular diseases: a focus on endothelial responses to inflammation Clin. Sci. (Lond.) 108 2005 205 213
42. M. Nakamura, H. Yoshida, N. Arakawa, S. Saitoh, M. Satoh, and K. Hiramori Effects of tumor necrosis factor-alpha on basal and stimulated endothelium-dependent vasomotion in human resistance vessel J. Cardiovasc. Pharmacol. 36 2000 487 492
43. A.M. Lefer, and X. Ma Cytokines and growth factors in endothelial dysfunction Crit. Care Med. 21 1993 S9 S14
44. N. Aoki, M. Siegfried, and A.M. Lefer Anti-EDRF effects of tumor necrosis factor in isolated, perfused cat carotid arteries Am. J. Physiol. 256 1989 H1509 H1512
45. S. Greenberg, J. Xie, Y. Wang, B. Cai, J. Kolls, and S. Nelson Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation J. Appl. Physiol. 74 1993 2394 2403
46. P. Wang, Z.F. Ba, and I.H. Chaudry Administration of tumor necrosis factor-alpha in vivo depresses endothelium-dependent relaxation Am. J. Physiol. 266 1994 H2535 H2541
47. J.B. Giardina, G.M. Green, K.L. Cockrell, J.P. Granger, and R.A. Khalil TNF-alpha enhances contraction and inhibits endothelial NO-cGMP relaxation in systemic vessels of pregnant rats Am. J. Physiol. Regul. Integr. Comp. Physiol. 283 2002 R130 R143
48. H.A. Piepot, A.B. Groeneveld, A.A. van Lambalgen, and P. Sipkema Tumor necrosis factor-alpha impairs endothelium-dependent relaxation of rat renal arteries, independent of tyrosine kinase Shock 17 2002 394 398
49. H.S. Murphy, J.A. Shayman, G.O. Till, M. Mahrougui, C.B. Owens, and U.S. Ryan Superoxide responses of endothelial cells to C5a and TNF-alpha: divergent signal transduction pathways Am. J. Physiol. 263 1992 L51 L59
50. S.S. Deshpande, P. Angkeow, J. Huang, M. Ozaki, and K. Irani Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species FASEB J. 14 2000 1705 1714
51. G.W. De Keulenaer, R.W. Alexander, M. Ushio-Fukai, N. Ishizaka, and K.K. Griendling Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle Biochem. J. 329 1998 653 657
52. Z. Ungvari, A. Csiszar, J.G. Edwards, P. Kaminski, M.S. Wolin, and G. Kaley Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase Arterioscler. Thromb. Vasc. Biol. 23 2003 418 424
53. E.A. Kowaluk, P. Seth, and H.-L. Fung Metabolic activation of sodium nitroprusside to nitric oxide in vascular smooth muscle J. Pharmacol. Exp. Ther. 262 1992 916 922
54. J.S. Stamler, D.J. Singel, and J. Loscalzo Biochemistry of nitric oxide and its redox-activated forms Science 258 1992 1898 1902
55. I.S. Severina, O.G. Bussygina, and N.B. Grigorjev Effect of nitroso complexes of some transition metals on the activity of soluble guanylate cyclase Biochem. Int. 26 1992 695 705
56. J.N. Bates, M.T. Baker, R. Guerra Jr., and D.G. Harrison Nitric oxide generation from nitroprusside by vascular tissue. Evidence that reduction of the nitroprusside anion and cyanide loss are required Biochem. Pharmacol. 42 1991 S157 S165
57. A.R. Butler, F.W. Flitney, and D.L.H.N.O. Williams nitrosonium ions, nitroxide ions, nitrosothiols and iron-nitrosyls in biology: a chemist's perspective Trends Pharmacol. Sci. 16 1995 18 22
58. B.T. Mellion, L.J. Ignarro, C.B. Myers, E.H. Ohlstein, B.A. Ballot, and A.L. Hyman Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation Mol. Pharmacol. 23 1983 653 664
59. S. Aleryani, E. Milo, Y. Rose, and P. Kostka Superoxide-mediated decomposition of biological S-nitrosothiols J. Biol. Chem. 273 1998 6041 6045
60. C.A. Gunnett, D.D. Heistad, D.J. Berg, and F.M. Faraci IL-10 deficiency increases superoxide and endothelial dysfunction during inflammation Am. J. Physiol. Heart Circ. Physiol. 279 2000 H1555 H1562
61. D.D. Lund, F.M. Faraci, F.J. Miller Jr, and D.D. Heistad Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits Circulation 101 2000 1027 1033
62. S. Wassmann, K. Wassmann, and G. Nickenig Modulation of oxidant and antioxidant enzyme expression and function in vascular cells Hypertension 44 2004 381 386
63. K.A. Dressler, S. Mathias, and R.N. Kolesnick Tumor necrosis factor-alpha activates the sphingomyelin signal transduction pathway in a cell-free system Science 255 1992 1715 1718
64. S. Mathias, K.A. Dressler, and R.N. Kolesnick Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha Proc. Natl. Acad. Sci. USA 88 1991 10009 10013
65. R. Kolesnick, and D.W. Golde Sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling Cell 77 1994 325 328
66. J.K. Pru, M.P. Lynch, J.S. Davis, and B.R. Rueda Signaling mechanisms in tumor necrosis factor alpha-induced death of microvascular endothelial cells of the corpus luteum Reprod. Biol. Endocrinol. 1 2003 17
67. S. Kinugawa, H. Huang, Z. Wang, P.M. Kaminski, M.S. Wolin, and T.H. Hintze A defect of neuronal nitric oxide synthase increases xanthine oxidase-derived superoxide anion and attenuates the control of myocardial oxygen consumption by nitric oxide derived from endothelial nitric oxide synthase Circ. Res. 96 2005 355 362
68. T. Force, and J.V. Bonventre Growth factors and mitogen-activated protein kinases Hypertension 31 1998 152 161
69. R.M. Berne The role of adenosine in the regulation of coronary blood flow Circ. Res. 47 1980 807 813
70. T. Minamino, M. Kitakaze, Y. Matsumura, K. Nishida, Y. Kato, and K. Hashimura Impact of coronary risk factors on contribution of nitric oxide and adenosine to metabolic coronary vasodilation in humans J. Am. Coll. Cardiol. 31 1998 1274 1279