Effect of Pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of Pravastatin)

American Journal of Cardiology

Volumn 88, Issue 11, 2001, Pages 1291-1294

  Masumoto, Akihiro ^a   Hirooka, Yoshitaka ^a   Hironaga, Kiyoshi ^a   Eshima, Kenichi ^a   Setoguchi, Soko ^a   Egashira, Kensuke ^a   Takeshita, Akira ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; N(G) METHYLARGININE; NITRATE; NITRIC OXIDE; NITRITE; NITROPRUSSIDE SODIUM; PRAVASTATIN; TRIACYLGLYCEROL;

ADULT; AGED; ARTERY DILATATION; BRACHIAL ARTERY; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY RISK; DRUG EFFECT; FOREARM BLOOD FLOW; HEART RATE; HUMAN; MEAN ARTERIAL PRESSURE; PRIORITY JOURNAL; REVIEW; TRIACYLGLYCEROL BLOOD LEVEL; URINARY EXCRETION; VASCULAR ENDOTHELIUM; VASCULAR RESISTANCE;

EID: 0035584083     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(01)02090-2     Document Type: Article

References (13)

1. Upregulation of inhibition of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
2. Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys
3. Effect of L-arginine on acetylcholine-induced endothelium-dependent vasodilation differs between the coronary and forearm vasculatures in humans
4. Effects of L-arginine on impaired acetylcholine-induced and ischemic vasodilation of the forearm in patients with heart failure
5. Long-term treatment with eicosapentaenoic acid augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilatation in patients with coronary artery disease
6. Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia
7. Simvastatin, an HMG-coenzyme: A reductase inhibitor, improves endothelial function within 1 month
8. Increased bioavailability of nitric oxide after lipid-lowering therapy in hypercholesterolemic patients
9. Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes: The RECIFE (REduction of Cholesterol in Ischemia and Function of the Endothelium) trial
10. Improvement of nitric oxide-dependent vasodilation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation
11. Rho, and rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration
12. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by rho GTPase
13. Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback of rho GTPase transcription